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Entry version 119 (08 May 2019)
Sequence version 1 (01 Aug 1991)
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Protein

Amicyanin

Gene

mauC

Organism
Paracoccus denitrificans
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Primary acceptor of electrons from methylamine dehydrogenase. Passes those electrons on either a soluble cytochrome c or to pseudoazurin.

<p>This subsection of the ‘Function’ section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Cu cationNote: Binds 1 copper ion per subunit.

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: methylamine degradation

This protein is involved in the pathway methylamine degradation, which is part of One-carbon metabolism.
View all proteins of this organism that are known to be involved in the pathway methylamine degradation and in One-carbon metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi79Copper1
Metal bindingi118Copper1
Metal bindingi121Copper1
Metal bindingi124Copper1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processElectron transport, Transport
LigandCopper, Metal-binding

Enzyme and pathway databases

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00895

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Amicyanin
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:mauC
Synonyms:ami
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiParacoccus denitrificans
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri266 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeParacoccus

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Periplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Chemistry databases

Drug and drug target database

More...
DrugBanki
DB02467 L-methionine (S)-S-oxide
DB08646 TRW3-(2-AMINO-3-HYDROXY-PROPYL)-6-(N'-CYCLOHEXYL-HYDRAZINO)OCTAHYDRO-INDOL-7-OL

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 261 PublicationAdd BLAST26
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000000284427 – 131AmicyaninAdd BLAST105

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
P22364, 3 interactors

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1131
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1AACX-ray1.31A27-131[»]
1AAJX-ray1.80A27-131[»]
1AANX-ray2.00A27-131[»]
1BXAX-ray1.30A27-131[»]
1MDAX-ray2.50A/B29-131[»]
1MG2X-ray2.25C/G/K/O27-131[»]
1MG3X-ray2.40C/G/K/O27-131[»]
1SF3X-ray1.05A27-131[»]
1SF5X-ray1.10A27-131[»]
1SFDX-ray0.99A/B27-131[»]
1SFHX-ray1.05A/B27-131[»]
1T5KX-ray1.40A/B/C/D27-131[»]
2GB2X-ray1.25A27-131[»]
2GBAX-ray0.92A27-131[»]
2GC4X-ray1.90C/G/K/O27-131[»]
2GC7X-ray1.90C/G/K/O27-131[»]
2IDQX-ray0.90A27-131[»]
2IDSX-ray1.00A27-131[»]
2IDTX-ray1.00A27-131[»]
2IDUX-ray0.95A27-131[»]
2J55X-ray2.15A/B27-131[»]
2J56X-ray2.10A/B27-131[»]
2J57X-ray2.25A/B/C/D27-131[»]
2MTAX-ray2.40A27-131[»]
2OV0X-ray0.75A27-131[»]
2QDVX-ray0.89A27-131[»]
2QDWX-ray0.92A27-131[»]
2RACX-ray1.30A27-131[»]
3IE9X-ray2.10A27-131[»]
3IEAX-ray2.20A27-131[»]
3L45Other1.80A27-131[»]
3PLYX-ray2.20A/B/C/D27-131[»]
3RYMX-ray1.70A/B/C/D27-131[»]
4P5RX-ray1.09A27-131[»]
4P5SX-ray1.02A27-131[»]

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P22364

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
P22364

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini27 – 131Plastocyanin-likeAdd BLAST105

Keywords - Domaini

Signal

Family and domain databases

Conserved Domains Database

More...
CDDi
cd13921 Amicyanin, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.420, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR035668 Amicyanin
IPR002386 Amicyanin/Pseudoazurin
IPR013475 Amicyanin_Para/Methyl
IPR000923 BlueCu_1
IPR028871 BlueCu_1_BS
IPR001235 Copper_blue_Plastocyanin
IPR008972 Cupredoxin

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00127 Copper-bind, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00155 AMICYANIN
PR00156 COPPERBLUE

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49503 SSF49503, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR02657 amicyanin, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00196 COPPER_BLUE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

P22364-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MISATKIRSC LAACVLAAFG ATGALADKAT IPSESPFAAA EVADGAIVVD
60 70 80 90 100
IAKMKYETPE LHVKVGDTVT WINREAMPHN VHFVAGVLGE AALKGPMMKK
110 120 130
EQAYSLTFTE AGTYDYHCTP HPFMRGKVVV E
Length:131
Mass (Da):13,983
Last modified:August 1, 1991 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF7352A865FD089DA
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X55665 Genomic DNA Translation: CAA39199.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A24407
S12972

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X55665 Genomic DNA Translation: CAA39199.1
PIRiA24407
S12972

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1AACX-ray1.31A27-131[»]
1AAJX-ray1.80A27-131[»]
1AANX-ray2.00A27-131[»]
1BXAX-ray1.30A27-131[»]
1MDAX-ray2.50A/B29-131[»]
1MG2X-ray2.25C/G/K/O27-131[»]
1MG3X-ray2.40C/G/K/O27-131[»]
1SF3X-ray1.05A27-131[»]
1SF5X-ray1.10A27-131[»]
1SFDX-ray0.99A/B27-131[»]
1SFHX-ray1.05A/B27-131[»]
1T5KX-ray1.40A/B/C/D27-131[»]
2GB2X-ray1.25A27-131[»]
2GBAX-ray0.92A27-131[»]
2GC4X-ray1.90C/G/K/O27-131[»]
2GC7X-ray1.90C/G/K/O27-131[»]
2IDQX-ray0.90A27-131[»]
2IDSX-ray1.00A27-131[»]
2IDTX-ray1.00A27-131[»]
2IDUX-ray0.95A27-131[»]
2J55X-ray2.15A/B27-131[»]
2J56X-ray2.10A/B27-131[»]
2J57X-ray2.25A/B/C/D27-131[»]
2MTAX-ray2.40A27-131[»]
2OV0X-ray0.75A27-131[»]
2QDVX-ray0.89A27-131[»]
2QDWX-ray0.92A27-131[»]
2RACX-ray1.30A27-131[»]
3IE9X-ray2.10A27-131[»]
3IEAX-ray2.20A27-131[»]
3L45Other1.80A27-131[»]
3PLYX-ray2.20A/B/C/D27-131[»]
3RYMX-ray1.70A/B/C/D27-131[»]
4P5RX-ray1.09A27-131[»]
4P5SX-ray1.02A27-131[»]
SMRiP22364
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP22364, 3 interactors

Chemistry databases

DrugBankiDB02467 L-methionine (S)-S-oxide
DB08646 TRW3-(2-AMINO-3-HYDROXY-PROPYL)-6-(N'-CYCLOHEXYL-HYDRAZINO)OCTAHYDRO-INDOL-7-OL

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayi
UPA00895

Miscellaneous databases

EvolutionaryTraceiP22364

Family and domain databases

CDDicd13921 Amicyanin, 1 hit
Gene3Di2.60.40.420, 1 hit
InterProiView protein in InterPro
IPR035668 Amicyanin
IPR002386 Amicyanin/Pseudoazurin
IPR013475 Amicyanin_Para/Methyl
IPR000923 BlueCu_1
IPR028871 BlueCu_1_BS
IPR001235 Copper_blue_Plastocyanin
IPR008972 Cupredoxin
PfamiView protein in Pfam
PF00127 Copper-bind, 1 hit
PRINTSiPR00155 AMICYANIN
PR00156 COPPERBLUE
SUPFAMiSSF49503 SSF49503, 1 hit
TIGRFAMsiTIGR02657 amicyanin, 1 hit
PROSITEiView protein in PROSITE
PS00196 COPPER_BLUE, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiAMCY_PARDE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P22364
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1991
Last sequence update: August 1, 1991
Last modified: May 8, 2019
This is version 119 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
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