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Protein

60 kDa chaperonin 2

Gene

groL2

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
Biological processStress response
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperonin 2UniRule annotation
Alternative name(s):
GroEL protein 2UniRule annotation
Protein Cpn60 2UniRule annotation
Gene namesi
Name:groL2UniRule annotation
Synonyms:cpn60-2, groEL-2UniRule annotation, groEL2UniRule annotation
Ordered Locus Names:sll0416
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesMerismopediaceaeSynechocystis
Proteomesi
  • UP000001425 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00000635762 – 55260 kDa chaperonin 2Add BLAST551

Proteomic databases

PaxDbiP22034
PRIDEiP22034

Expressioni

Inductioni

By stress conditions e.g. heat shock.

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

GO - Molecular functioni

Protein-protein interaction databases

IntActiP22034, 1 interactor
STRINGi1148.SYNGTS_2276

Structurei

3D structure databases

ProteinModelPortaliP22034
SMRiP22034
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000076290
InParanoidiP22034
KOiK04077
OMAiCVIKVGA
PhylomeDBiP22034

Family and domain databases

CDDicd03344 GroEL, 1 hit
Gene3Di1.10.560.10, 2 hits
3.30.260.10, 2 hits
3.50.7.10, 1 hit
HAMAPiMF_00600 CH60, 1 hit
InterProiView protein in InterPro
IPR018370 Chaperonin_Cpn60_CS
IPR001844 Chaprnin_Cpn60
IPR002423 Cpn60/TCP-1
IPR027409 GroEL-like_apical_dom_sf
IPR027413 GROEL-like_equatorial_sf
IPR027410 TCP-1-like_intermed_sf
PfamiView protein in Pfam
PF00118 Cpn60_TCP1, 1 hit
PRINTSiPR00298 CHAPERONIN60
SUPFAMiSSF48592 SSF48592, 2 hits
SSF52029 SSF52029, 1 hit
SSF54849 SSF54849, 1 hit
TIGRFAMsiTIGR02348 GroEL, 1 hit
PROSITEiView protein in PROSITE
PS00296 CHAPERONINS_CPN60, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P22034-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKLISFKDE SRRSLEAGIN ALADAVRITL GPKGRNVLLE KQYGAPQIVN
60 70 80 90 100
DGITVAKEIE LSNPEENAGA KLIQEVASKT KEIAGDGTTT ATIIAQALVR
110 120 130 140 150
EGLRNVAAGA NPVALRRGIE KVTTFLVQEI EAVAKPVEGS AIAQVATVSS
160 170 180 190 200
GNDPEVGAMI ADAMDKVTKD GVITVEESKS LNTELEVVEG MQIDRGYISP
210 220 230 240 250
YFITDSDRQL VEFDNPLILI TDKKISAIAE LVPVLEAVAR AGRPLLIIAE
260 270 280 290 300
DIEGEALATL VVNKARGVLN VAAIKAPAFG DRRKAVLQDI AILTGGSVIS
310 320 330 340 350
EDIGLSLDTV SLDQLGQAVK ATLEKDNTIL VAGADKRASA GVKERIEQLR
360 370 380 390 400
KEYAASDSDY DKEKIQERIA KLAGGVAVIK VGAATETELK DRKLRIEDAL
410 420 430 440 450
NATKAAVEEG IVPGGGTTLI RLAGKIESFK AQLSNDEERV AADIIAKALE
460 470 480 490 500
APLHQLASNA GVEGSVIVEK VKEATGNQGY NVITGKIEDL IAAGIIDPAK
510 520 530 540 550
VVRSALQNAA SIAGMVLTTE ALVVEKPEPA APAMPDMGGM GGMGGMGGMG

MM
Length:552
Mass (Da):57,774
Last modified:January 23, 2007 - v4
Checksum:i106B30E99515E8AA
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti152 – 153ND → TN in AAA27284 (PubMed:1670771).Curated2
Sequence conflicti278Missing in AAA27284 (PubMed:1670771).Curated1
Sequence conflicti335D → H in AAA27284 (PubMed:1670771).Curated1
Sequence conflicti338A → R in AAA27284 (PubMed:1670771).Curated1
Sequence conflicti531A → P in AAA27284 (PubMed:1670771).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M57517 Genomic DNA Translation: AAA27284.1
BA000022 Genomic DNA Translation: BAA10240.1
PIRiS74322

Genome annotation databases

EnsemblBacteriaiBAA10240; BAA10240; BAA10240
KEGGisyn:sll0416

Similar proteinsi

Entry informationi

Entry nameiCH602_SYNY3
AccessioniPrimary (citable) accession number: P22034
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1991
Last sequence update: January 23, 2007
Last modified: May 23, 2018
This is version 140 of the entry and version 4 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

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