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UniProtKB - P21630 (BRAG_PSEAE)
Protein
High-affinity branched-chain amino acid transport ATP-binding protein BraG
Gene
braG
Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Functioni
Component of the high affinity leucine, isoleucine, valine, transport system (LIV-I), which is operative without Na+ and is specific for alanine and threonine, in addition to branched-chain amino acids.
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 34 – 41 | ATPPROSITE-ProRule annotation | 8 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- branched-chain amino acid transmembrane transporter activity Source: InterPro
GO - Biological processi
- D-alanine transport Source: PseudoCAP
- L-alanine transport Source: PseudoCAP
- L-amino acid transport Source: GO_Central
Keywordsi
Biological process | Amino-acid transport, Transport |
Ligand | ATP-binding, Nucleotide-binding |
Protein family/group databases
TCDBi | 3.A.1.4.8, the atp-binding cassette (abc) superfamily |
Names & Taxonomyi
Protein namesi | Recommended name: High-affinity branched-chain amino acid transport ATP-binding protein BraG |
Gene namesi | Name:braG Ordered Locus Names:PA1070 |
Organismi | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) |
Taxonomic identifieri | 208964 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas › |
Proteomesi |
|
Organism-specific databases
PseudoCAPi | PA1070 |
Subcellular locationi
Plasma membrane
- Cell inner membrane Curated; Peripheral membrane protein Curated
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000091949 | 1 – 233 | High-affinity branched-chain amino acid transport ATP-binding protein BraGAdd BLAST | 233 |
Proteomic databases
PaxDbi | P21630 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 2 – 233 | ABC transporterPROSITE-ProRule annotationAdd BLAST | 232 |
Sequence similaritiesi
Belongs to the ABC transporter superfamily.Curated
Phylogenomic databases
HOGENOMi | CLU_000604_1_2_6 |
InParanoidi | P21630 |
OMAi | IMMQKIM |
PhylomeDBi | P21630 |
Family and domain databases
Gene3Di | 3.40.50.300, 1 hit |
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR030660, ABC_branched_ATPase_LivF/BraG IPR003439, ABC_transporter-like_ATP-bd IPR017871, ABC_transporter-like_CS IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00005, ABC_tran, 1 hit |
PIRSFi | PIRSF039137, ABC_branched_ATPase, 1 hit |
SMARTi | View protein in SMART SM00382, AAA, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS00211, ABC_TRANSPORTER_1, 1 hit PS50893, ABC_TRANSPORTER_2, 1 hit |
i Sequence
Sequence statusi: Complete.
P21630-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLSFDKVSTY YGKIQALHDV SVEVKKGEIV TLIGANGAGK STLLMTLCGS
60 70 80 90 100
PQAASGSIRY EGEELVGLPS STIMRKSIAV VPEGRRVFSR LTVEENLAMG
110 120 130 140 150
GFFTDKDDYQ VQMDKVLELF PRLKERYEQR AGTMSGGEQQ MLAIGRALMS
160 170 180 190 200
KPKLLLLDEP SLGLAPIIIQ QIFEIIEQLR REGVTVFLVE QNANQALKLA
210 220 230
DRAYVLENGR IVMHDTGAAL LTNPKVRDAY LGG
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D90223 Genomic DNA Translation: BAA14258.1 AE004091 Genomic DNA Translation: AAG04459.1 |
PIRi | E36125 |
RefSeqi | NP_249761.1, NC_002516.2 WP_003086389.1, NZ_QZGE01000006.1 |
Genome annotation databases
EnsemblBacteriai | AAG04459; AAG04459; PA1070 |
GeneIDi | 878069 |
KEGGi | pae:PA1070 |
PATRICi | fig|208964.12.peg.1108 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D90223 Genomic DNA Translation: BAA14258.1 AE004091 Genomic DNA Translation: AAG04459.1 |
PIRi | E36125 |
RefSeqi | NP_249761.1, NC_002516.2 WP_003086389.1, NZ_QZGE01000006.1 |
3D structure databases
AlphaFoldDBi | P21630 |
SMRi | P21630 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 287.DR97_873 |
Protein family/group databases
TCDBi | 3.A.1.4.8, the atp-binding cassette (abc) superfamily |
Proteomic databases
PaxDbi | P21630 |
Protocols and materials databases
DNASUi | 878069 |
Genome annotation databases
EnsemblBacteriai | AAG04459; AAG04459; PA1070 |
GeneIDi | 878069 |
KEGGi | pae:PA1070 |
PATRICi | fig|208964.12.peg.1108 |
Organism-specific databases
PseudoCAPi | PA1070 |
Phylogenomic databases
HOGENOMi | CLU_000604_1_2_6 |
InParanoidi | P21630 |
OMAi | IMMQKIM |
PhylomeDBi | P21630 |
Family and domain databases
Gene3Di | 3.40.50.300, 1 hit |
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR030660, ABC_branched_ATPase_LivF/BraG IPR003439, ABC_transporter-like_ATP-bd IPR017871, ABC_transporter-like_CS IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00005, ABC_tran, 1 hit |
PIRSFi | PIRSF039137, ABC_branched_ATPase, 1 hit |
SMARTi | View protein in SMART SM00382, AAA, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS00211, ABC_TRANSPORTER_1, 1 hit PS50893, ABC_TRANSPORTER_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | BRAG_PSEAE | |
Accessioni | P21630Primary (citable) accession number: P21630 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 1, 1991 |
Last sequence update: | May 1, 1991 | |
Last modified: | May 25, 2022 | |
This is version 132 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families