We are aiming to switch to the new UniProt website on Monday, May 9. Please explore and share your feedback.
Take me to the new website.
UniProtKB - P21560 (CBP3_YEAST)
Protein
Protein CBP3, mitochondrial
Gene
CBP3
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
Chaperone required for the assembly of ubiquinol-cytochrome c reductase of the mitochondrial respiratory chain.
Miscellaneous
Present with 14200 molecules/cell in log phase SD medium.1 Publication
GO - Molecular functioni
- mRNA binding Source: SGD
- ribosome binding Source: SGD
GO - Biological processi
- mitochondrial respiratory chain complex III assembly Source: ComplexPortal
- positive regulation of mitochondrial translation Source: SGD
- protein stabilization Source: ComplexPortal
Keywordsi
Molecular function | Chaperone |
Names & Taxonomyi
Protein namesi | Recommended name: Protein CBP3, mitochondrial |
Gene namesi | Name:CBP3 Ordered Locus Names:YPL215W ORF Names:P1775 |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
SGDi | S000006136, CBP3 |
VEuPathDBi | FungiDB:YPL215W |
Subcellular locationi
Mitochondrion
Mitochondrion
- Cbp3p-Cbp6 complex Source: SGD
- integral component of mitochondrial membrane Source: SGD
- mitochondrial ribosome Source: SGD
- mitochondrion Source: SGD
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 152 – 169 | HelicalSequence analysisAdd BLAST | 18 |
Keywords - Cellular componenti
Membrane, MitochondrionPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transit peptidei | 1 – 38 | MitochondrionSequence analysisAdd BLAST | 38 | |
ChainiPRO_0000004775 | 39 – 335 | Protein CBP3, mitochondrialAdd BLAST | 297 |
Proteomic databases
MaxQBi | P21560 |
PaxDbi | P21560 |
PRIDEi | P21560 |
Interactioni
Binary interactionsi
P21560
With | #Exp. | IntAct |
---|---|---|
CBP6 [P07253] | 4 | EBI-4134,EBI-4142 |
MRPL4 [P36517] | 3 | EBI-4134,EBI-402 |
Protein-protein interaction databases
BioGRIDi | 35970, 73 interactors |
ComplexPortali | CPX-384, CBP3-CBP6 complex |
DIPi | DIP-69N |
IntActi | P21560, 10 interactors |
MINTi | P21560 |
STRINGi | 4932.YPL215W |
Miscellaneous databases
RNActi | P21560, protein |
Family & Domainsi
Sequence similaritiesi
Belongs to the CBP3 family.Curated
Keywords - Domaini
Transit peptide, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG2873, Eukaryota |
GeneTreei | ENSGT00390000018118 |
HOGENOMi | CLU_051390_1_0_1 |
InParanoidi | P21560 |
OMAi | SQWFQIT |
Family and domain databases
InterProi | View protein in InterPro IPR021150, Ubiq_cyt_c_chap/UPF0174 IPR007129, Ubiqinol_cyt_c_chaperone_CPB3 |
PANTHERi | PTHR12184, PTHR12184, 1 hit |
Pfami | View protein in Pfam PF03981, Ubiq_cyt_C_chap, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P21560-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MMSVNRFTSG RLPVFLRKSP FYYSRAYLHQ TCVFKQNKET AQDSPELLAK
60 70 80 90 100
SSHLNSKPLD VSNKAPVKTA QNKIPLAHSK YESSKYELPK WKEALGELVI
110 120 130 140 150
RAFHLDMDRV RAGPVAGSYY YKICKEQGLQ YEDEPLSETA KYFYEDLKLP
160 170 180 190 200
RTFSQWFQIT VLHEWILFVR MRAMPFKYGR NYQQKLVDRT FSDIELRLFE
210 220 230 240 250
EMKVNSGRIA DQYLKDFNTQ LRGAIFAYDE GFATDDGTLA TAVWRNLFGG
260 270 280 290 300
RKNIDMVHLE SVVRYIYSQL YVLSRLSDRE FATGKFKFVP PGVKVEKLTP
310 320 330
KQEEELKAKT IAKYEALDKD PKTLPSERSR LSYTN
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | J04830 Genomic DNA Translation: AAA34475.1 Z73571 Genomic DNA Translation: CAA97930.1 BK006949 Genomic DNA Translation: DAA11221.1 |
PIRi | A34290 |
RefSeqi | NP_015109.1, NM_001184029.1 |
Genome annotation databases
EnsemblFungii | YPL215W_mRNA; YPL215W; YPL215W |
GeneIDi | 855886 |
KEGGi | sce:YPL215W |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | J04830 Genomic DNA Translation: AAA34475.1 Z73571 Genomic DNA Translation: CAA97930.1 BK006949 Genomic DNA Translation: DAA11221.1 |
PIRi | A34290 |
RefSeqi | NP_015109.1, NM_001184029.1 |
3D structure databases
SMRi | P21560 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 35970, 73 interactors |
ComplexPortali | CPX-384, CBP3-CBP6 complex |
DIPi | DIP-69N |
IntActi | P21560, 10 interactors |
MINTi | P21560 |
STRINGi | 4932.YPL215W |
Proteomic databases
MaxQBi | P21560 |
PaxDbi | P21560 |
PRIDEi | P21560 |
Genome annotation databases
EnsemblFungii | YPL215W_mRNA; YPL215W; YPL215W |
GeneIDi | 855886 |
KEGGi | sce:YPL215W |
Organism-specific databases
SGDi | S000006136, CBP3 |
VEuPathDBi | FungiDB:YPL215W |
Phylogenomic databases
eggNOGi | KOG2873, Eukaryota |
GeneTreei | ENSGT00390000018118 |
HOGENOMi | CLU_051390_1_0_1 |
InParanoidi | P21560 |
OMAi | SQWFQIT |
Miscellaneous databases
PROi | PR:P21560 |
RNActi | P21560, protein |
Family and domain databases
InterProi | View protein in InterPro IPR021150, Ubiq_cyt_c_chap/UPF0174 IPR007129, Ubiqinol_cyt_c_chaperone_CPB3 |
PANTHERi | PTHR12184, PTHR12184, 1 hit |
Pfami | View protein in Pfam PF03981, Ubiq_cyt_C_chap, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | CBP3_YEAST | |
Accessioni | P21560Primary (citable) accession number: P21560 Secondary accession number(s): D6W3F5 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 1, 1991 |
Last sequence update: | May 1, 1991 | |
Last modified: | February 23, 2022 | |
This is version 165 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD - Yeast chromosome XVI
Yeast (Saccharomyces cerevisiae) chromosome XVI: entries and gene names - SIMILARITY comments
Index of protein domains and families