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Protein

Zinc finger protein 10

Gene

ZNF10

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri206 – 232C2H2-type 1; atypicalPROSITE-ProRule annotationAdd BLAST27
Zinc fingeri265 – 287C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri293 – 315C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri321 – 343C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri349 – 371C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri377 – 399C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri405 – 427C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri433 – 455C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri461 – 483C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri489 – 511C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri517 – 539C2H2-type 11; atypicalPROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-212436 Generic Transcription Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 10
Alternative name(s):
Zinc finger protein KOX1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF10
Synonyms:KOX1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000256223.5

Human Gene Nomenclature Database

More...
HGNCi
HGNC:12879 ZNF10

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
194538 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P21506

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
7556

Open Targets

More...
OpenTargetsi
ENSG00000256223

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA37468

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF10

Domain mapping of disease mutations (DMDM)

More...
DMDMi
55977778

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000473321 – 573Zinc finger protein 10Add BLAST573

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P21506

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P21506

PeptideAtlas

More...
PeptideAtlasi
P21506

PRoteomics IDEntifications database

More...
PRIDEi
P21506

ProteomicsDB human proteome resource

More...
ProteomicsDBi
53873

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P21506

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P21506

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000256223 Expressed in 185 organ(s), highest expression level in pituitary gland

CleanEx database of gene expression profiles

More...
CleanExi
HS_ZNF10

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P21506 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P21506 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA003204

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts (via the KRAB domain) with TRIM28 (via the RBCC domain).1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
113388, 7 interactors

Protein interaction database and analysis system

More...
IntActi
P21506, 4 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000248211

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
P21506

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P21506

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini14 – 85KRABPROSITE-ProRule annotationAdd BLAST72

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri206 – 232C2H2-type 1; atypicalPROSITE-ProRule annotationAdd BLAST27
Zinc fingeri265 – 287C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri293 – 315C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri321 – 343C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri349 – 371C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri377 – 399C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri405 – 427C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri433 – 455C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri461 – 483C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri489 – 511C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri517 – 539C2H2-type 11; atypicalPROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721 Eukaryota
COG5048 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000162949

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000234617

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG018163

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P21506

KEGG Orthology (KO)

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KOi
K09228

Identification of Orthologs from Complete Genome Data

More...
OMAi
VVHHRTH

Database of Orthologous Groups

More...
OrthoDBi
EOG091G02KC

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P21506

TreeFam database of animal gene trees

More...
TreeFami
TF337898

Family and domain databases

Conserved Domains Database

More...
CDDi
cd07765 KRAB_A-box, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 10 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 10 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 7 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 10 hits
PS50157 ZINC_FINGER_C2H2_2, 11 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

P21506-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDAKSLTAWS RTLVTFKDVF VDFTREEWKL LDTAQQIVYR NVMLENYKNL
60 70 80 90 100
VSLGYQLTKP DVILRLEKGE EPWLVEREIH QETHPDSETA FEIKSSVSSR
110 120 130 140 150
SIFKDKQSCD IKMEGMARND LWYLSLEEVW KCRDQLDKYQ ENPERHLRQV
160 170 180 190 200
AFTQKKVLTQ ERVSESGKYG GNCLLPAQLV LREYFHKRDS HTKSLKHDLV
210 220 230 240 250
LNGHQDSCAS NSNECGQTFC QNIHLIQFAR THTGDKSYKC PDNDNSLTHG
260 270 280 290 300
SSLGISKGIH REKPYECKEC GKFFSWRSNL TRHQLIHTGE KPYECKECGK
310 320 330 340 350
SFSRSSHLIG HQKTHTGEEP YECKECGKSF SWFSHLVTHQ RTHTGDKLYT
360 370 380 390 400
CNQCGKSFVH SSRLIRHQRT HTGEKPYECP ECGKSFRQST HLILHQRTHV
410 420 430 440 450
RVRPYECNEC GKSYSQRSHL VVHHRIHTGL KPFECKDCGK CFSRSSHLYS
460 470 480 490 500
HQRTHTGEKP YECHDCGKSF SQSSALIVHQ RIHTGEKPYE CCQCGKAFIR
510 520 530 540 550
KNDLIKHQRI HVGEETYKCN QCGIIFSQNS PFIVHQIAHT GEQFLTCNQC
560 570
GTALVNTSNL IGYQTNHIRE NAY
Length:573
Mass (Da):66,455
Last modified:November 23, 2004 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5C850DBC8FF4A064
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F8WD46F8WD46_HUMAN
Zinc finger protein 10
ZNF10
439Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F5GZ75F5GZ75_HUMAN
Zinc finger protein 10
ZNF10
72Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F5H311F5H311_HUMAN
Zinc finger protein 10
ZNF10
47Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F5H0R3F5H0R3_HUMAN
Zinc finger protein 10
ZNF10
43Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti149 – 282Missing (PubMed:2288909).CuratedAdd BLAST134
Sequence conflicti374E → H in CAA36558 (PubMed:2288909).Curated1
Sequence conflicti514E → A in CAA36558 (PubMed:2288909).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_052746227Q → R. Corresponds to variant dbSNP:rs11147259Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X52332 mRNA Translation: CAA36558.1
AK314784 mRNA Translation: BAG37318.1
CH471218 Genomic DNA Translation: EAW54791.1
BC024182 mRNA Translation: AAH24182.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS9283.1

Protein sequence database of the Protein Information Resource

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PIRi
S10397

NCBI Reference Sequences

More...
RefSeqi
NP_056209.2, NM_015394.4

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.573983

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000248211; ENSP00000248211; ENSG00000256223
ENST00000426665; ENSP00000393814; ENSG00000256223

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
7556

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:7556

UCSC genome browser

More...
UCSCi
uc001ulq.4 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X52332 mRNA Translation: CAA36558.1
AK314784 mRNA Translation: BAG37318.1
CH471218 Genomic DNA Translation: EAW54791.1
BC024182 mRNA Translation: AAH24182.1
CCDSiCCDS9283.1
PIRiS10397
RefSeqiNP_056209.2, NM_015394.4
UniGeneiHs.573983

3D structure databases

ProteinModelPortaliP21506
SMRiP21506
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi113388, 7 interactors
IntActiP21506, 4 interactors
STRINGi9606.ENSP00000248211

PTM databases

iPTMnetiP21506
PhosphoSitePlusiP21506

Polymorphism and mutation databases

BioMutaiZNF10
DMDMi55977778

Proteomic databases

MaxQBiP21506
PaxDbiP21506
PeptideAtlasiP21506
PRIDEiP21506
ProteomicsDBi53873

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
7556
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000248211; ENSP00000248211; ENSG00000256223
ENST00000426665; ENSP00000393814; ENSG00000256223
GeneIDi7556
KEGGihsa:7556
UCSCiuc001ulq.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
7556
DisGeNETi7556
EuPathDBiHostDB:ENSG00000256223.5

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZNF10
HGNCiHGNC:12879 ZNF10
HPAiHPA003204
MIMi194538 gene
neXtProtiNX_P21506
OpenTargetsiENSG00000256223
PharmGKBiPA37468

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00940000162949
HOGENOMiHOG000234617
HOVERGENiHBG018163
InParanoidiP21506
KOiK09228
OMAiVVHHRTH
OrthoDBiEOG091G02KC
PhylomeDBiP21506
TreeFamiTF337898

Enzyme and pathway databases

ReactomeiR-HSA-212436 Generic Transcription Pathway

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
ZNF10 human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
ZNF10

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
7556

Protein Ontology

More...
PROi
PR:P21506

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000256223 Expressed in 185 organ(s), highest expression level in pituitary gland
CleanExiHS_ZNF10
ExpressionAtlasiP21506 baseline and differential
GenevisibleiP21506 HS

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 10 hits
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 10 hits
SUPFAMiSSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 7 hits
PROSITEiView protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 10 hits
PS50157 ZINC_FINGER_C2H2_2, 11 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZNF10_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P21506
Secondary accession number(s): B2RBS1, Q8TC91
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 1991
Last sequence update: November 23, 2004
Last modified: December 5, 2018
This is version 187 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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