UniProtKB - P21503 (YCAD_ECOLI)
Protein
Uncharacterized MFS-type transporter YcaD
Gene
ycaD
Organism
Escherichia coli (strain K12)
Status
Functioni
GO - Molecular functioni
- transmembrane transporter activity Source: UniProtKB-UniRule
Keywordsi
Biological process | Transport |
Enzyme and pathway databases
BioCyci | EcoCyc:YCAD-MONOMER |
Protein family/group databases
TCDBi | 2.A.1.26.1, the major facilitator superfamily (mfs) |
Names & Taxonomyi
Protein namesi | Recommended name: Uncharacterized MFS-type transporter YcaD |
Gene namesi | Name:ycaD Ordered Locus Names:b0898, JW0881 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
Plasma Membrane
- plasma membrane Source: EcoCyc
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 13 | CytoplasmicSequence analysisAdd BLAST | 13 | |
Transmembranei | 14 – 34 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 35 – 44 | PeriplasmicSequence analysis | 10 | |
Transmembranei | 45 – 65 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 66 – 78 | CytoplasmicSequence analysisAdd BLAST | 13 | |
Transmembranei | 79 – 99 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 100 – 101 | PeriplasmicSequence analysis | 2 | |
Transmembranei | 102 – 122 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 123 – 130 | CytoplasmicSequence analysis | 8 | |
Transmembranei | 131 – 151 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 152 – 156 | PeriplasmicSequence analysis | 5 | |
Transmembranei | 157 – 177 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 178 – 203 | CytoplasmicSequence analysisAdd BLAST | 26 | |
Transmembranei | 204 – 224 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 225 – 234 | PeriplasmicSequence analysis | 10 | |
Transmembranei | 235 – 255 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 256 – 269 | CytoplasmicSequence analysisAdd BLAST | 14 | |
Transmembranei | 270 – 290 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 291 – 311 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 312 – 324 | CytoplasmicSequence analysisAdd BLAST | 13 | |
Transmembranei | 325 – 345 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 346 – 347 | PeriplasmicSequence analysis | 2 | |
Transmembranei | 348 – 368 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 369 – 382 | CytoplasmicSequence analysisAdd BLAST | 14 |
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000084889 | 1 – 382 | Uncharacterized MFS-type transporter YcaDAdd BLAST | 382 |
Proteomic databases
PaxDbi | P21503 |
PRIDEi | P21503 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4261691, 135 interactors |
STRINGi | 511145.b0898 |
Family & Domainsi
Sequence similaritiesi
Belongs to the major facilitator superfamily. YcaD (TC 2.A.1.26) family. [View classification]Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG0477, Bacteria |
HOGENOMi | CLU_035018_1_2_6 |
InParanoidi | P21503 |
PhylomeDBi | P21503 |
Family and domain databases
HAMAPi | MF_01149, MFS_YcaD, 1 hit |
InterProi | View protein in InterPro IPR011701, MFS IPR020846, MFS_dom IPR036259, MFS_trans_sf IPR023745, MFS_YcaD |
Pfami | View protein in Pfam PF07690, MFS_1, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit |
i Sequence
Sequence statusi: Complete.
P21503-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSTYTQPVML LLSGLLLLTL AIAVLNTLVP LWLAQEHMST WQVGVVSSSY
60 70 80 90 100
FTGNLVGTLL TGYVIKRIGF NRSYYLASFI FAAGCAGLGL MIGFWSWLAW
110 120 130 140 150
RFVAGVGCAM IWVVVESALM CSGTSRNRGR LLAAYMMVYY VGTFLGQLLV
160 170 180 190 200
SKVSTELMSV LPWVTGLTLA GILPLLFTRV LNQQAENHDS TSITSMLKLR
210 220 230 240 250
QARLGVNGCI ISGIVLGSLY GLMPLYLNHK GVSNASIGFW MAVLVSAGIL
260 270 280 290 300
GQWPIGRLAD KFGRLLVLRV QVFVVILGSI AMLSQAAMAP ALFILGAAGF
310 320 330 340 350
TLYPVAMAWA CEKVEHHQLV AMNQALLLSY TVGSLLGPSF TAMLMQNFSD
360 370 380
NLLFIMIASV SFIYLLMLLR NAGHTPKPVA HV
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC73984.1 AP009048 Genomic DNA Translation: BAA35630.1 J03412 Genomic DNA Translation: AAA83847.1 |
PIRi | A64829 |
RefSeqi | NP_415418.1, NC_000913.3 WP_000109259.1, NZ_SSZK01000002.1 |
Genome annotation databases
EnsemblBacteriai | AAC73984; AAC73984; b0898 BAA35630; BAA35630; BAA35630 |
GeneIDi | 57728309 945515 |
KEGGi | ecj:JW0881 eco:b0898 |
PATRICi | fig|1411691.4.peg.1378 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC73984.1 AP009048 Genomic DNA Translation: BAA35630.1 J03412 Genomic DNA Translation: AAA83847.1 |
PIRi | A64829 |
RefSeqi | NP_415418.1, NC_000913.3 WP_000109259.1, NZ_SSZK01000002.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 4261691, 135 interactors |
STRINGi | 511145.b0898 |
Protein family/group databases
TCDBi | 2.A.1.26.1, the major facilitator superfamily (mfs) |
Proteomic databases
PaxDbi | P21503 |
PRIDEi | P21503 |
Genome annotation databases
EnsemblBacteriai | AAC73984; AAC73984; b0898 BAA35630; BAA35630; BAA35630 |
GeneIDi | 57728309 945515 |
KEGGi | ecj:JW0881 eco:b0898 |
PATRICi | fig|1411691.4.peg.1378 |
Organism-specific databases
EchoBASEi | EB1224 |
Phylogenomic databases
eggNOGi | COG0477, Bacteria |
HOGENOMi | CLU_035018_1_2_6 |
InParanoidi | P21503 |
PhylomeDBi | P21503 |
Enzyme and pathway databases
BioCyci | EcoCyc:YCAD-MONOMER |
Miscellaneous databases
PROi | PR:P21503 |
Family and domain databases
HAMAPi | MF_01149, MFS_YcaD, 1 hit |
InterProi | View protein in InterPro IPR011701, MFS IPR020846, MFS_dom IPR036259, MFS_trans_sf IPR023745, MFS_YcaD |
Pfami | View protein in Pfam PF07690, MFS_1, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | YCAD_ECOLI | |
Accessioni | P21503Primary (citable) accession number: P21503 Secondary accession number(s): P75834 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 1, 1991 |
Last sequence update: | November 1, 1997 | |
Last modified: | February 10, 2021 | |
This is version 146 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families