UniProtKB - P21397 (AOFA_HUMAN)
Protein
Amine oxidase [flavin-containing] A
Gene
MAOA
Organism
Homo sapiens (Human)
Status
Functioni
Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine.
Catalytic activityi
- EC:1.4.3.4
Cofactori
FAD2 Publications
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sitei | 335 | Important for substrate specificityBy similarity | 1 | |
Sitei | 374 | Important for catalytic activity | 1 |
GO - Molecular functioni
- primary amine oxidase activity Source: Ensembl
GO - Biological processi
- cellular biogenic amine metabolic process Source: ProtInc
- cytokine-mediated signaling pathway Source: Reactome
- dopamine catabolic process Source: ParkinsonsUK-UCL
- neurotransmitter catabolic process Source: UniProtKB-KW
- neurotransmitter metabolic process Source: Reactome
- positive regulation of signal transduction Source: Ensembl
Keywordsi
Molecular function | Oxidoreductase |
Biological process | Catecholamine metabolism, Neurotransmitter degradation |
Ligand | FAD, Flavoprotein |
Enzyme and pathway databases
BioCyci | MetaCyc:HS01798-MONOMER |
BRENDAi | 1.4.3.4, 2681 |
PathwayCommonsi | P21397 |
Reactomei | R-HSA-141333, Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB R-HSA-181430, Norepinephrine Neurotransmitter Release Cycle R-HSA-379397, Enzymatic degradation of dopamine by COMT R-HSA-379398, Enzymatic degradation of Dopamine by monoamine oxidase R-HSA-380612, Metabolism of serotonin R-HSA-5579012, Defective MAOA causes Brunner syndrome (BRUNS) R-HSA-6785807, Interleukin-4 and Interleukin-13 signaling |
SABIO-RKi | P21397 |
SIGNORi | P21397 |
Names & Taxonomyi
Protein namesi | Recommended name: Amine oxidase [flavin-containing] A (EC:1.4.3.4)Alternative name(s): Monoamine oxidase type A Short name: MAO-A |
Gene namesi | Name:MAOA |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000189221.9 |
HGNCi | HGNC:6833, MAOA |
MIMi | 309850, gene |
neXtProti | NX_P21397 |
Subcellular locationi
Cytosol
- cytosol Source: HPA
Mitochondrion
- mitochondrial outer membrane Source: ParkinsonsUK-UCL
- mitochondrion Source: HPA
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 497 | Cytoplasmic1 PublicationAdd BLAST | 497 | |
Transmembranei | 498 – 518 | Helical; Anchor for type IV membrane proteinAdd BLAST | 21 | |
Topological domaini | 519 – 527 | Mitochondrial intermembrane1 Publication | 9 |
Keywords - Cellular componenti
Membrane, Mitochondrion, Mitochondrion outer membranePathology & Biotechi
Involvement in diseasei
Brunner syndrome (BRNRS)1 Publication
The disease is caused by mutations affecting the gene represented in this entry.
Disease descriptionA form of X-linked non-dysmorphic mild mental retardation. Male patients are affected by borderline mental retardation and exhibit abnormal behavior, including disturbed regulation of impulsive aggression. Obligate female carriers have normal intelligence and behavior.
Related information in OMIMMutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 165 | C → S: No loss of activity. 1 Publication | 1 | |
Mutagenesisi | 266 | C → S: No loss of activity. 1 Publication | 1 | |
Mutagenesisi | 306 | C → S: No loss of activity. 1 Publication | 1 | |
Mutagenesisi | 321 | C → S: No loss of activity. 1 Publication | 1 | |
Mutagenesisi | 323 | C → S: No loss of activity. 1 Publication | 1 | |
Mutagenesisi | 374 | C → S: Complete loss of activity. 1 Publication | 1 | |
Mutagenesisi | 398 | C → S: No loss of activity. 1 Publication | 1 | |
Mutagenesisi | 406 | C → S: Complete loss of activity. 1 Publication | 1 |
Keywords - Diseasei
Disease mutation, Mental retardationOrganism-specific databases
DisGeNETi | 4128 |
MalaCardsi | MAOA |
MIMi | 300615, phenotype |
OpenTargetsi | ENSG00000189221 |
Orphaneti | 3057, Monoamine oxidase A deficiency |
PharmGKBi | PA236 |
Miscellaneous databases
Pharosi | P21397, Tclin |
Chemistry databases
ChEMBLi | CHEMBL1951 |
DrugBanki | DB01472, 4-Methoxyamphetamine DB00918, Almotriptan DB00182, Amphetamine DB04889, Bicifadine DB13876, Brofaromine DB01445, Bufotenine DB06774, Capsaicin DB04017, Clorgiline DB09130, Copper DB05205, CX157 DB07641, Decyl(dimethyl)phosphine oxide DB00988, Dopamine DB01363, Ephedra sinica root DB00668, Epinephrine DB12329, Eravacycline DB01175, Escitalopram DB03147, Flavin adenine dinucleotide DB14914, Flortaucipir F-18 DB00614, Furazolidone DB07919, Harmine DB04818, Iproniazid DB01247, Isocarboxazid DB00601, Linezolid DB01577, Metamfetamine DB00805, Minaprine DB01442, MMDA DB01171, Moclobemide DB08804, Nandrolone decanoate DB00952, Naratriptan DB04820, Nialamide DB00184, Nicotine DB04821, Nomifensine DB06412, Oxymetholone DB01626, Pargyline DB00780, Phenelzine DB00191, Phentermine DB00388, Phenylephrine DB00397, Phenylpropanolamine DB09244, Pirlindole DB04850, Posizolid DB00721, Procaine DB01168, Procarbazine DB00571, Propranolol DB00852, Pseudoephedrine DB09363, Rauwolfia serpentina root DB00140, Riboflavin DB00953, Rizatriptan DB06654, Safinamide DB01037, Selegiline DB01104, Sertraline DB00669, Sumatriptan DB14569, Tedizolid DB09042, Tedizolid phosphate DB00624, Testosterone DB13943, Testosterone cypionate DB13944, Testosterone enanthate DB13946, Testosterone undecanoate DB09245, Toloxatone DB00752, Tranylcypromine DB15328, Ubrogepant DB04832, Zimelidine DB00315, Zolmitriptan DB00909, Zonisamide |
DrugCentrali | P21397 |
GuidetoPHARMACOLOGYi | 2489 |
Polymorphism and mutation databases
BioMutai | MAOA |
DMDMi | 113978 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000099850 | 1 – 527 | Amine oxidase [flavin-containing] AAdd BLAST | 527 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 1 | N-acetylmethionine1 Publication | 1 | |
Modified residuei | 383 | PhosphoserineBy similarity | 1 | |
Modified residuei | 406 | S-8alpha-FAD cysteineCombined sources1 Publication | 1 |
Keywords - PTMi
Acetylation, PhosphoproteinProteomic databases
EPDi | P21397 |
jPOSTi | P21397 |
MassIVEi | P21397 |
PaxDbi | P21397 |
PeptideAtlasi | P21397 |
PRIDEi | P21397 |
ProteomicsDBi | 4005 53866 [P21397-1] |
PTM databases
iPTMneti | P21397 |
PhosphoSitePlusi | P21397 |
SwissPalmi | P21397 |
Expressioni
Tissue specificityi
Heart, liver, duodenum, blood vessels and kidney.
Gene expression databases
Bgeei | ENSG00000189221, Expressed in small intestine and 238 other tissues |
ExpressionAtlasi | P21397, baseline and differential |
Genevisiblei | P21397, HS |
Organism-specific databases
HPAi | ENSG00000189221, Low tissue specificity |
Interactioni
Subunit structurei
Monomer, homo- or heterodimer (containing two subunits of similar size). Each subunit contains a covalently bound flavin. Enzymatically active as monomer.
2 PublicationsBinary interactionsi
P21397
With | #Exp. | IntAct |
---|---|---|
MAOB [P27338] | 2 | EBI-1190845,EBI-3911344 |
Protein-protein interaction databases
BioGRIDi | 110301, 7 interactors |
IntActi | P21397, 6 interactors |
MINTi | P21397 |
STRINGi | 9606.ENSP00000340684 |
Chemistry databases
BindingDBi | P21397 |
Miscellaneous databases
RNActi | P21397, protein |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | P21397 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P21397 |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 520 – 522 | Interaction with membrane phospholipid headgroupsCurated | 3 |
Sequence similaritiesi
Belongs to the flavin monoamine oxidase family.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0029, Eukaryota |
GeneTreei | ENSGT00940000160514 |
HOGENOMi | CLU_004498_0_1_1 |
InParanoidi | P21397 |
OMAi | EWTRGAY |
PhylomeDBi | P21397 |
TreeFami | TF313314 |
Family and domain databases
Gene3Di | 3.50.50.60, 1 hit |
InterProi | View protein in InterPro IPR002937, Amino_oxidase IPR036188, FAD/NAD-bd_sf IPR001613, Flavin_amine_oxidase |
Pfami | View protein in Pfam PF01593, Amino_oxidase, 1 hit |
PRINTSi | PR00757, AMINEOXDASEF |
SUPFAMi | SSF51905, SSF51905, 1 hit |
s (2)i Sequence
Sequence statusi: Complete.
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketIsoform 1 (identifier: P21397-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MENQEKASIA GHMFDVVVIG GGISGLSAAK LLTEYGVSVL VLEARDRVGG
60 70 80 90 100
RTYTIRNEHV DYVDVGGAYV GPTQNRILRL SKELGIETYK VNVSERLVQY
110 120 130 140 150
VKGKTYPFRG AFPPVWNPIA YLDYNNLWRT IDNMGKEIPT DAPWEAQHAD
160 170 180 190 200
KWDKMTMKEL IDKICWTKTA RRFAYLFVNI NVTSEPHEVS ALWFLWYVKQ
210 220 230 240 250
CGGTTRIFSV TNGGQERKFV GGSGQVSERI MDLLGDQVKL NHPVTHVDQS
260 270 280 290 300
SDNIIIETLN HEHYECKYVI NAIPPTLTAK IHFRPELPAE RNQLIQRLPM
310 320 330 340 350
GAVIKCMMYY KEAFWKKKDY CGCMIIEDED APISITLDDT KPDGSLPAIM
360 370 380 390 400
GFILARKADR LAKLHKEIRK KKICELYAKV LGSQEALHPV HYEEKNWCEE
410 420 430 440 450
QYSGGCYTAY FPPGIMTQYG RVIRQPVGRI FFAGTETATK WSGYMEGAVE
460 470 480 490 500
AGERAAREVL NGLGKVTEKD IWVQEPESKD VPAVEITHTF WERNLPSVSG
510 520
LLKIIGFSTS VTALGFVLYK YKLLPRS
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 397 | W → M AA sequence (PubMed:3178846).Curated | 1 |
Mass spectrometryi
Molecular mass is 60512±6 Da. Determined by ESI. 1 Publication
Polymorphismi
A polymorphism 1.2 kb upstream of the MAOA coding sequences consists of a 30-bp repeated sequence present in 3, 3.5, 4, or 5 copies. The polymorphism affect transcriptional activity of the MAOA gene promoter. Alleles with 3.5 or 4 copies of the repeat sequence are transcribed 2 to 10 times more efficiently than those with 3 or 5 copies of the repeat.
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_036545 | 15 | D → E in a breast cancer sample; somatic mutation. 1 Publication | 1 | |
Natural variantiVAR_064573 | 188 | E → K1 PublicationCorresponds to variant dbSNP:rs77698881Ensembl. | 1 | |
Natural variantiVAR_071963 | 266 | C → F Probable disease-associated variant found in a family with Brunner syndrome-like behavioral disturbances; reduced activity. 1 PublicationCorresponds to variant dbSNP:rs587777457EnsemblClinVar. | 1 | |
Natural variantiVAR_014795 | 314 | F → V. Corresponds to variant dbSNP:rs1799835Ensembl. | 1 | |
Natural variantiVAR_014796 | 520 | K → R. Corresponds to variant dbSNP:rs1800466EnsemblClinVar. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_045173 | 1 – 133 | Missing in isoform 2. 1 PublicationAdd BLAST | 133 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M69226 mRNA Translation: AAA59549.1 M68840 mRNA Translation: AAA59548.1 X60806 Genomic DNA No translation available. X60807 Genomic DNA No translation available. X60808 Genomic DNA No translation available. X60809 Genomic DNA No translation available. X60810 Genomic DNA No translation available. X60811 Genomic DNA No translation available. X60812 Genomic DNA No translation available. X60813 Genomic DNA No translation available. X60814 Genomic DNA No translation available. X60815 Genomic DNA No translation available. X60816 Genomic DNA No translation available. X60817 Genomic DNA No translation available. X60818 Genomic DNA No translation available. X60819 Genomic DNA No translation available. M68857 , M68843, M68844, M68845, M68846, M68847, M68848, M68849, M68850, M68851, M68852, M68853, M68854, M68855, M68856 Genomic DNA Translation: AAA59547.1 AK293926 mRNA Translation: BAG57307.1 AL109855 Genomic DNA No translation available. BX530072 Genomic DNA No translation available. BX537147 Genomic DNA No translation available. BX537148 Genomic DNA No translation available. BC008064 mRNA Translation: AAH08064.1 M89636 Genomic DNA Translation: AAB46385.1 S81371 Genomic DNA Translation: AAD14361.1 S72704 Genomic DNA Translation: AAD14113.1 |
CCDSi | CCDS14260.1 [P21397-1] CCDS59163.1 [P21397-2] |
PIRi | A36175 |
RefSeqi | NP_000231.1, NM_000240.3 [P21397-1] NP_001257387.1, NM_001270458.1 [P21397-2] |
Genome annotation databases
Ensembli | ENST00000338702; ENSP00000340684; ENSG00000189221 [P21397-1] ENST00000542639; ENSP00000440846; ENSG00000189221 [P21397-2] |
GeneIDi | 4128 |
KEGGi | hsa:4128 |
UCSCi | uc011mkw.3, human [P21397-1] |
Keywords - Coding sequence diversityi
Alternative splicing, PolymorphismSimilar proteinsi
Cross-referencesi
Web resourcesi
Wikipedia Monoamine oxidase entry |
Protein Spotlight Approaching happiness - Issue 172 of August 2015 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M69226 mRNA Translation: AAA59549.1 M68840 mRNA Translation: AAA59548.1 X60806 Genomic DNA No translation available. X60807 Genomic DNA No translation available. X60808 Genomic DNA No translation available. X60809 Genomic DNA No translation available. X60810 Genomic DNA No translation available. X60811 Genomic DNA No translation available. X60812 Genomic DNA No translation available. X60813 Genomic DNA No translation available. X60814 Genomic DNA No translation available. X60815 Genomic DNA No translation available. X60816 Genomic DNA No translation available. X60817 Genomic DNA No translation available. X60818 Genomic DNA No translation available. X60819 Genomic DNA No translation available. M68857 , M68843, M68844, M68845, M68846, M68847, M68848, M68849, M68850, M68851, M68852, M68853, M68854, M68855, M68856 Genomic DNA Translation: AAA59547.1 AK293926 mRNA Translation: BAG57307.1 AL109855 Genomic DNA No translation available. BX530072 Genomic DNA No translation available. BX537147 Genomic DNA No translation available. BX537148 Genomic DNA No translation available. BC008064 mRNA Translation: AAH08064.1 M89636 Genomic DNA Translation: AAB46385.1 S81371 Genomic DNA Translation: AAD14361.1 S72704 Genomic DNA Translation: AAD14113.1 |
CCDSi | CCDS14260.1 [P21397-1] CCDS59163.1 [P21397-2] |
PIRi | A36175 |
RefSeqi | NP_000231.1, NM_000240.3 [P21397-1] NP_001257387.1, NM_001270458.1 [P21397-2] |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1H8Q | model | - | A | 14-468 | [»] | |
2BXR | X-ray | 3.00 | A/B | 1-527 | [»] | |
2BXS | X-ray | 3.15 | A/B | 1-527 | [»] | |
2Z5X | X-ray | 2.20 | A | 12-524 | [»] | |
2Z5Y | X-ray | 2.17 | A | 12-524 | [»] | |
SMRi | P21397 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 110301, 7 interactors |
IntActi | P21397, 6 interactors |
MINTi | P21397 |
STRINGi | 9606.ENSP00000340684 |
Chemistry databases
BindingDBi | P21397 |
ChEMBLi | CHEMBL1951 |
DrugBanki | DB01472, 4-Methoxyamphetamine DB00918, Almotriptan DB00182, Amphetamine DB04889, Bicifadine DB13876, Brofaromine DB01445, Bufotenine DB06774, Capsaicin DB04017, Clorgiline DB09130, Copper DB05205, CX157 DB07641, Decyl(dimethyl)phosphine oxide DB00988, Dopamine DB01363, Ephedra sinica root DB00668, Epinephrine DB12329, Eravacycline DB01175, Escitalopram DB03147, Flavin adenine dinucleotide DB14914, Flortaucipir F-18 DB00614, Furazolidone DB07919, Harmine DB04818, Iproniazid DB01247, Isocarboxazid DB00601, Linezolid DB01577, Metamfetamine DB00805, Minaprine DB01442, MMDA DB01171, Moclobemide DB08804, Nandrolone decanoate DB00952, Naratriptan DB04820, Nialamide DB00184, Nicotine DB04821, Nomifensine DB06412, Oxymetholone DB01626, Pargyline DB00780, Phenelzine DB00191, Phentermine DB00388, Phenylephrine DB00397, Phenylpropanolamine DB09244, Pirlindole DB04850, Posizolid DB00721, Procaine DB01168, Procarbazine DB00571, Propranolol DB00852, Pseudoephedrine DB09363, Rauwolfia serpentina root DB00140, Riboflavin DB00953, Rizatriptan DB06654, Safinamide DB01037, Selegiline DB01104, Sertraline DB00669, Sumatriptan DB14569, Tedizolid DB09042, Tedizolid phosphate DB00624, Testosterone DB13943, Testosterone cypionate DB13944, Testosterone enanthate DB13946, Testosterone undecanoate DB09245, Toloxatone DB00752, Tranylcypromine DB15328, Ubrogepant DB04832, Zimelidine DB00315, Zolmitriptan DB00909, Zonisamide |
DrugCentrali | P21397 |
GuidetoPHARMACOLOGYi | 2489 |
PTM databases
iPTMneti | P21397 |
PhosphoSitePlusi | P21397 |
SwissPalmi | P21397 |
Polymorphism and mutation databases
BioMutai | MAOA |
DMDMi | 113978 |
Proteomic databases
EPDi | P21397 |
jPOSTi | P21397 |
MassIVEi | P21397 |
PaxDbi | P21397 |
PeptideAtlasi | P21397 |
PRIDEi | P21397 |
ProteomicsDBi | 4005 53866 [P21397-1] |
Protocols and materials databases
Antibodypediai | 10933, 445 antibodies |
DNASUi | 4128 |
Genome annotation databases
Ensembli | ENST00000338702; ENSP00000340684; ENSG00000189221 [P21397-1] ENST00000542639; ENSP00000440846; ENSG00000189221 [P21397-2] |
GeneIDi | 4128 |
KEGGi | hsa:4128 |
UCSCi | uc011mkw.3, human [P21397-1] |
Organism-specific databases
CTDi | 4128 |
DisGeNETi | 4128 |
EuPathDBi | HostDB:ENSG00000189221.9 |
GeneCardsi | MAOA |
HGNCi | HGNC:6833, MAOA |
HPAi | ENSG00000189221, Low tissue specificity |
MalaCardsi | MAOA |
MIMi | 300615, phenotype 309850, gene |
neXtProti | NX_P21397 |
OpenTargetsi | ENSG00000189221 |
Orphaneti | 3057, Monoamine oxidase A deficiency |
PharmGKBi | PA236 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG0029, Eukaryota |
GeneTreei | ENSGT00940000160514 |
HOGENOMi | CLU_004498_0_1_1 |
InParanoidi | P21397 |
OMAi | EWTRGAY |
PhylomeDBi | P21397 |
TreeFami | TF313314 |
Enzyme and pathway databases
BioCyci | MetaCyc:HS01798-MONOMER |
BRENDAi | 1.4.3.4, 2681 |
PathwayCommonsi | P21397 |
Reactomei | R-HSA-141333, Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB R-HSA-181430, Norepinephrine Neurotransmitter Release Cycle R-HSA-379397, Enzymatic degradation of dopamine by COMT R-HSA-379398, Enzymatic degradation of Dopamine by monoamine oxidase R-HSA-380612, Metabolism of serotonin R-HSA-5579012, Defective MAOA causes Brunner syndrome (BRUNS) R-HSA-6785807, Interleukin-4 and Interleukin-13 signaling |
SABIO-RKi | P21397 |
SIGNORi | P21397 |
Miscellaneous databases
BioGRID-ORCSi | 4128, 4 hits in 471 CRISPR screens |
ChiTaRSi | MAOA, human |
EvolutionaryTracei | P21397 |
GeneWikii | Monoamine_oxidase_A |
GenomeRNAii | 4128 |
Pharosi | P21397, Tclin |
PROi | PR:P21397 |
RNActi | P21397, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000189221, Expressed in small intestine and 238 other tissues |
ExpressionAtlasi | P21397, baseline and differential |
Genevisiblei | P21397, HS |
Family and domain databases
Gene3Di | 3.50.50.60, 1 hit |
InterProi | View protein in InterPro IPR002937, Amino_oxidase IPR036188, FAD/NAD-bd_sf IPR001613, Flavin_amine_oxidase |
Pfami | View protein in Pfam PF01593, Amino_oxidase, 1 hit |
PRINTSi | PR00757, AMINEOXDASEF |
SUPFAMi | SSF51905, SSF51905, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | AOFA_HUMAN | |
Accessioni | P21397Primary (citable) accession number: P21397 Secondary accession number(s): B4DF46, Q16426 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 1, 1991 |
Last sequence update: | May 1, 1991 | |
Last modified: | December 2, 2020 | |
This is version 221 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencing, Reference proteomeDocuments
- Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families - Protein Spotlight
Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries - Human chromosome X
Human chromosome X: entries, gene names and cross-references to MIM - Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations