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UniProtKB - P21278 (GNA11_MOUSE)

Entry version 188 (29 Sep 2021)
Sequence version 1 (01 May 1991)
Previous versions | rss
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Protein

Guanine nucleotide-binding protein subunit alpha-11

Gene

Gna11

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Acts as an activator of phospholipase C. Transduces FFAR4 signaling in response to long-chain fatty acids (LCFAs).

By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi53MagnesiumBy similarity1
Metal bindingi186MagnesiumBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei331GTP; via amide nitrogenBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi46 – 53GTPBy similarity8
Nucleotide bindingi180 – 186GTPBy similarity7
Nucleotide bindingi205 – 209GTPBy similarity5
Nucleotide bindingi274 – 277GTPBy similarity4

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTransducer
LigandGTP-binding, Magnesium, Metal-binding, Nucleotide-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-MMU-112043, PLC beta mediated events
R-MMU-202040, G-protein activation
R-MMU-399997, Acetylcholine regulates insulin secretion
R-MMU-416476, G alpha (q) signalling events
R-MMU-418592, ADP signalling through P2Y purinoceptor 1
R-MMU-428930, Thromboxane signalling through TP receptor
R-MMU-434316, Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion
R-MMU-456926, Thrombin signalling through proteinase activated receptors (PARs)
R-MMU-6814122, Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Guanine nucleotide-binding protein subunit alpha-11
Short name:
G alpha-11
Short name:
G-protein subunit alpha-11
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Gna11
Synonyms:Gna-11
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:95766, Gna11

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSMUSG00000034781

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cell membrane, Cytoplasm, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002037471 – 359Guanine nucleotide-binding protein subunit alpha-11Add BLAST359

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position(s) and the type of covalently attached lipid group(s).<p><a href='/help/lipid' target='_top'>More...</a></p>Lipidationi9S-palmitoyl cysteineBy similarity1
Lipidationi10S-palmitoyl cysteineBy similarity1

Keywords - PTMi

Lipoprotein, Palmitate

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		P21278

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		P21278

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P21278

PeptideAtlas

More...PeptideAtlasi		P21278

PRoteomics IDEntifications database

More...PRIDEi		P21278

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		271410

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		P21278

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		P21278

SwissPalm database of S-palmitoylation events

More...SwissPalmi		P21278

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSMUSG00000034781, Expressed in jejunum and 317 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		P21278, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.

Interacts with RGS22.

Interacts with NTSR1 (By similarity).

By similarity

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		199961, 15 interactors

Database of interacting proteins

More...DIPi		DIP-603N

Protein interaction database and analysis system

More...IntActi		P21278, 2 interactors

STRING: functional protein association networks

More...STRINGi		10090.ENSMUSP00000043190

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		P21278, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P21278

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini38 – 359G-alphaPROSITE-ProRule annotationAdd BLAST322

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni41 – 54G1 motifPROSITE-ProRule annotationAdd BLAST14
Regioni178 – 186G2 motifPROSITE-ProRule annotation9
Regioni201 – 210G3 motifPROSITE-ProRule annotation10
Regioni270 – 277G4 motifPROSITE-ProRule annotation8
Regioni329 – 334G5 motifPROSITE-ProRule annotation6

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the G-alpha family. G(q) subfamily.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0085, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000161033

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_014184_6_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P21278

Identification of Orthologs from Complete Genome Data

More...OMAi		GNCISQM

Database of Orthologous Groups

More...OrthoDBi		754573at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		P21278

TreeFam database of animal gene trees

More...TreeFami		TF300673

Family and domain databases

Conserved Domains Database

More...CDDi		cd00066, G-alpha, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.400.10, 1 hit
3.40.50.300, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000654, Gprotein_alpha_Q
IPR001019, Gprotein_alpha_su
IPR011025, GproteinA_insert
IPR027417, P-loop_NTPase

The PANTHER Classification System

More...PANTHERi		PTHR10218, PTHR10218, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00503, G-alpha, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00318, GPROTEINA
PR00442, GPROTEINAQ

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00275, G_alpha, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF47895, SSF47895, 1 hit
SSF52540, SSF52540, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51882, G_ALPHA, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P21278-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTLESMMACC LSDEVKESKR INAEIEKQLR RDKRDARREL KLLLLGTGES 
        60         70         80         90        100
GKSTFIKQMR IIHGAGYSEE DKRGFTKLVY QNIFTAMQAM VRAMETLKIL 
       110        120        130        140        150
YKYEQNKANA LLIREVDVEK VTTFEHQYVN AIKTLWSDPG VQECYDRRRE 
       160        170        180        190        200
FQLSDSAKYY LTDVDRIATV GYLPTQQDVL RVRVPTTGII EYPFDLENII 
       210        220        230        240        250
FRMVDVGGQR SERRKWIHCF ENVTSIMFLV ALSEYDQVLV ESDNENRMEE 
       260        270        280        290        300
SKALFRTIIT YPWFQNSSVI LFLNKKDLLE DKILHSHLVD YFPEFDGPQR 
       310        320        330        340        350
DAQAAREFIL KMFVDLNPDS DKIIYSHFTC ATDTENIRFV FAAVKDTILQ 

LNLKEYNLV
Length:359
Mass (Da):42,024
Last modified:May 1, 1991 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA33D2D6C6C62F8D5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti77K → L in AAB36839 (PubMed:8838318).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
M55411 mRNA Translation: AAA63305.1
U37413, U37411, U37412 Genomic DNA Translation: AAB36839.1
M57617 mRNA Translation: AAA63301.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS24061.1

Protein sequence database of the Protein Information Resource

More...PIRi		B33833
B38414, RGMS11

NCBI Reference Sequences

More...RefSeqi		NP_034431.1, NM_010301.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000043604; ENSMUSP00000043190; ENSMUSG00000034781

Database of genes from NCBI RefSeq genomes

More...GeneIDi		14672

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mmu:14672

UCSC genome browser

More...UCSCi		uc007gil.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M55411 mRNA Translation: AAA63305.1
U37413, U37411, U37412 Genomic DNA Translation: AAB36839.1
M57617 mRNA Translation: AAA63301.1
CCDSiCCDS24061.1
PIRiB33833
B38414, RGMS11
RefSeqiNP_034431.1, NM_010301.3

3D structure databases

SMRiP21278
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi199961, 15 interactors
DIPiDIP-603N
IntActiP21278, 2 interactors
STRINGi10090.ENSMUSP00000043190

PTM databases

iPTMnetiP21278
PhosphoSitePlusiP21278
SwissPalmiP21278

Proteomic databases

EPDiP21278
jPOSTiP21278
PaxDbiP21278
PeptideAtlasiP21278
PRIDEiP21278
ProteomicsDBi271410

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		53288, 266 antibodies

The DNASU plasmid repository

More...DNASUi		14672

Genome annotation databases

EnsembliENSMUST00000043604; ENSMUSP00000043190; ENSMUSG00000034781
GeneIDi14672
KEGGimmu:14672
UCSCiuc007gil.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		2767
MGIiMGI:95766, Gna11
VEuPathDBiHostDB:ENSMUSG00000034781

Phylogenomic databases

eggNOGiKOG0085, Eukaryota
GeneTreeiENSGT00940000161033
HOGENOMiCLU_014184_6_0_1
InParanoidiP21278
OMAiGNCISQM
OrthoDBi754573at2759
PhylomeDBiP21278
TreeFamiTF300673

Enzyme and pathway databases

ReactomeiR-MMU-112043, PLC beta mediated events
R-MMU-202040, G-protein activation
R-MMU-399997, Acetylcholine regulates insulin secretion
R-MMU-416476, G alpha (q) signalling events
R-MMU-418592, ADP signalling through P2Y purinoceptor 1
R-MMU-428930, Thromboxane signalling through TP receptor
R-MMU-434316, Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion
R-MMU-456926, Thrombin signalling through proteinase activated receptors (PARs)
R-MMU-6814122, Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		14672, 4 hits in 63 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		Gna11, mouse

Protein Ontology

More...PROi		PR:P21278
RNActiP21278, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSMUSG00000034781, Expressed in jejunum and 317 other tissues
GenevisibleiP21278, MM

Family and domain databases

CDDicd00066, G-alpha, 1 hit
Gene3Di1.10.400.10, 1 hit
3.40.50.300, 1 hit
InterProiView protein in InterPro
IPR000654, Gprotein_alpha_Q
IPR001019, Gprotein_alpha_su
IPR011025, GproteinA_insert
IPR027417, P-loop_NTPase
PANTHERiPTHR10218, PTHR10218, 1 hit
PfamiView protein in Pfam
PF00503, G-alpha, 1 hit
PRINTSiPR00318, GPROTEINA
PR00442, GPROTEINAQ
SMARTiView protein in SMART
SM00275, G_alpha, 1 hit
SUPFAMiSSF47895, SSF47895, 1 hit
SSF52540, SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS51882, G_ALPHA, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiGNA11_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P21278
Secondary accession number(s): Q61939
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 1991
Last sequence update: May 1, 1991
Last modified: September 29, 2021
This is version 188 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Direct protein sequencing, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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