UniProtKB - P21190 (IME1_YEAST)
Protein
Meiosis-inducing protein 1
Gene
IME1
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
Transcription factor required for sporulation and for early sporulation-specific genes expression. Positive regulator of SME1/IME2 expression. Directly activates expression of SLZ1 during meiosis.1 Publication
GO - Molecular functioni
- transcription factor binding Source: SGD
GO - Biological processi
- meiotic cell cycle Source: UniProtKB-KW
- positive regulation of transcription by RNA polymerase II Source: SGD
- pseudohyphal growth Source: SGD
- regulation of meiotic nuclear division Source: UniProtKB
- regulation of transcription by RNA polymerase II Source: SGD
- sporulation resulting in formation of a cellular spore Source: UniProtKB-KW
Keywordsi
Molecular function | Activator, Repressor |
Biological process | Meiosis, Sporulation, Transcription, Transcription regulation |
Names & Taxonomyi
Protein namesi | Recommended name: Meiosis-inducing protein 1 |
Gene namesi | Name:IME1 Ordered Locus Names:YJR094C ORF Names:J1916 |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
EuPathDBi | FungiDB:YJR094C |
SGDi | S000003854, IME1 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000084181 | 1 – 360 | Meiosis-inducing protein 1Add BLAST | 360 |
Proteomic databases
PaxDbi | P21190 |
PTM databases
iPTMneti | P21190 |
Expressioni
Inductioni
Starvation of yeast cells may stimulate activity of IME1 through a post-translational mechanism.
Interactioni
Subunit structurei
Interacts with UME6.
Binary interactionsi
Hide detailsGO - Molecular functioni
- transcription factor binding Source: SGD
Protein-protein interaction databases
BioGRIDi | 33848, 249 interactors |
ComplexPortali | CPX-1415, IME1-UME6 transcription activation complex |
DIPi | DIP-1567N |
IntActi | P21190, 2 interactors |
MINTi | P21190 |
STRINGi | 4932.YJR094C |
Miscellaneous databases
RNActi | P21190, protein |
Family & Domainsi
Phylogenomic databases
eggNOGi | ENOG502SCKA, Eukaryota |
HOGENOMi | CLU_889059_0_0_1 |
InParanoidi | P21190 |
OMAi | YETNTNA |
i Sequence
Sequence statusi: Complete.
P21190-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MQADMHGKLH AALEDGFFLF PFEQQQQPNI YYDTTTDQED RPCFSFGSTI
60 70 80 90 100
SPRSWHFEKS DKIASSQLQN LVHTQPIHLI NPQILFNEEF LNLENIDSQP
110 120 130 140 150
ISKETKTTKD CTMATGPERG KKSSESTRSS SLSSLFSNDE SASTFHSSFN
160 170 180 190 200
NHDNFQKSNR NGDDIDISDT IKYETNTNAQ KDIKIFQENF EFNEFPYTQD
210 220 230 240 250
FYPYTTNYTY SKPTNIHESI NSKNTDSYSQ YQDQFPPHTD NIHSFNNRHY
260 270 280 290 300
SNHKSTNCNY YNNTSNNNNA SDNVYEADPF IDEPQVPSYY YPLEIAFDVE
310 320 330 340 350
KSPPPSLQKL NSKELEFLKK LNSKLSRYAA AYSFSSSNDQ DYYDKVRFQE
360
ISYKFSKTYS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M37188 Genomic DNA Translation: AAA86790.1 X52152 Genomic DNA Translation: CAA36400.1 Z49594 Genomic DNA Translation: CAA89622.1 BK006943 Genomic DNA Translation: DAA08878.1 |
PIRi | S57115 |
RefSeqi | NP_012627.1, NM_001181751.1 |
Genome annotation databases
EnsemblFungii | YJR094C_mRNA; YJR094C; YJR094C |
GeneIDi | 853556 |
KEGGi | sce:YJR094C |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M37188 Genomic DNA Translation: AAA86790.1 X52152 Genomic DNA Translation: CAA36400.1 Z49594 Genomic DNA Translation: CAA89622.1 BK006943 Genomic DNA Translation: DAA08878.1 |
PIRi | S57115 |
RefSeqi | NP_012627.1, NM_001181751.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 33848, 249 interactors |
ComplexPortali | CPX-1415, IME1-UME6 transcription activation complex |
DIPi | DIP-1567N |
IntActi | P21190, 2 interactors |
MINTi | P21190 |
STRINGi | 4932.YJR094C |
PTM databases
iPTMneti | P21190 |
Proteomic databases
PaxDbi | P21190 |
Genome annotation databases
EnsemblFungii | YJR094C_mRNA; YJR094C; YJR094C |
GeneIDi | 853556 |
KEGGi | sce:YJR094C |
Organism-specific databases
EuPathDBi | FungiDB:YJR094C |
SGDi | S000003854, IME1 |
Phylogenomic databases
eggNOGi | ENOG502SCKA, Eukaryota |
HOGENOMi | CLU_889059_0_0_1 |
InParanoidi | P21190 |
OMAi | YETNTNA |
Miscellaneous databases
PROi | PR:P21190 |
RNActi | P21190, protein |
Family and domain databases
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | IME1_YEAST | |
Accessioni | P21190Primary (citable) accession number: P21190 Secondary accession number(s): D6VWR2 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 1, 1991 |
Last sequence update: | May 1, 1991 | |
Last modified: | December 2, 2020 | |
This is version 139 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD - Yeast chromosome X
Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names