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UniProtKB - P21187 (PABP_DROME)

Entry version 192 (12 Aug 2020)
Sequence version 3 (27 Sep 2005)
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Protein

Polyadenylate-binding protein

Gene

pAbp

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Binds the poly(A) tail of mRNA (PubMed:2125288). Since it interacts with the cap-associating translation initiation factor eIF4G, it is likely that it functions by linking Atx2 to the cap-binding complex (PubMed:28388438). Forms a complex with tyf and Atx2 which functions in adult circadian pacemaker neurons to sustain circadian rhythms likely by switching between activator and repressor modes of post-transcriptional regulation via interaction with Lsm12a or me31B, respectively (PubMed:28388438). The activator complex (Atx2-tyf activator complex) activates the TYF-dependent translation of per to maintain 24 hour periodicity in circadian locomotor behaviors, whereas the repressor complex (Atx2-Not1 repressor complex) promotes Not1-dependent post-transcriptional gene silencing and supports high-amplitude circadian rhythms in a per-independent manner (PubMed:28388438). In 0-1 hour embryos, forms a ribonucleoprotein complex (RNP) with me31B, eIF4E1, tral and cup which binds to various mRNAs including maternal mRNAs, and downregulates their expression during the maternal-to-zygotic transition (PubMed:28875934).3 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRNA-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-DME-156827, L13a-mediated translational silencing of Ceruloplasmin expression
R-DME-429947, Deadenylation of mRNA
R-DME-450408, AUF1 (hnRNP D0) binds and destabilizes mRNA
R-DME-72649, Translation initiation complex formation
R-DME-975956, Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-DME-975957, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Polyadenylate-binding protein
Short name:
PABP
Short name:
Poly(A)-binding protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:pAbp
ORF Names:CG5119
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2R

Organism-specific databases

Drosophila genome database

More...FlyBasei		FBgn0265297, pAbp

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000817131 – 634Polyadenylate-binding proteinAdd BLAST634

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P21187

PRoteomics IDEntifications database

More...PRIDEi		P21187

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed during the first 5 hrs of embryogenesis (at protein level) (PubMed:28875934). Expressed both maternally and zygotically throughout development (PubMed:2125288).2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		FBgn0265297, Expressed in cleaving embryo and 41 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		P21187, DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Core component of the neuromuscular Atx2 complex, composed of at least Atx2, tyf, pAbp, Lsm12a (PubMed:28388438).

Interacts with Atx2 (via PAM2 motif) (PubMed:28388438). Atx2 and pAbp form a subcomplex that can associate with the 5' cap of pre-mRNAs independently of tyf, Lsm12a or me31B (PubMed:28388438).

Forms a ribonucleoprotein complex (RNP) containing at least me31B, eIF4E1, cup, tral and pAbp; this interaction is required for the translational silencing of maternal mRNAs during the maternal-to-zygotic transition (PubMed:28875934). In 1-5 hour embryos, interaction with me31B is severely reduced and there is no detected interaction with cup and tral, however interaction with eIF4E1 and eIF4G1 remains unchanged (PubMed:28875934).

Interacts with gw; this interaction interferes with the binding of pAbp to eIF4G and is required for miRNA-mediated silencing (PubMed:19797087).

Interacts with larp (PubMed:19631203).

4 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		62753, 62 interactors

Database of interacting proteins

More...DIPi		DIP-52140N

The Eukaryotic Linear Motif resource for Functional Sites in Proteins

More...ELMi		P21187

Protein interaction database and analysis system

More...IntActi		P21187, 18 interactors

Molecular INTeraction database

More...MINTi		P21187

STRING: functional protein association networks

More...STRINGi		7227.FBpp0085915

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P21187

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini2 – 80RRM 1PROSITE-ProRule annotationAdd BLAST79
Domaini90 – 167RRM 2PROSITE-ProRule annotationAdd BLAST78
Domaini181 – 259RRM 3PROSITE-ProRule annotationAdd BLAST79
Domaini285 – 362RRM 4PROSITE-ProRule annotationAdd BLAST78
Domaini552 – 629PABCPROSITE-ProRule annotationAdd BLAST78

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the polyadenylate-binding protein type-1 family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0123, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000169027

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_012062_22_2_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P21187

KEGG Orthology (KO)

More...KOi		K13126

Identification of Orthologs from Complete Genome Data

More...OMAi		MQPAVFY

Database of Orthologous Groups

More...OrthoDBi		1027234at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		P21187

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.30.70.330, 4 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR012677, Nucleotide-bd_a/b_plait_sf
IPR036053, PABP-dom
IPR006515, PABP_1234
IPR002004, PABP_HYD
IPR035979, RBD_domain_sf
IPR000504, RRM_dom

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00658, PABP, 1 hit
PF00076, RRM_1, 4 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00517, PolyA, 1 hit
SM00360, RRM, 4 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF54928, SSF54928, 2 hits
SSF63570, SSF63570, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR01628, PABP-1234, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51309, PABC, 1 hit
PS50102, RRM, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P21187-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASLYVGDLP QDVNESGLFD KFSSAGPVLS IRVCRDVITR RSLGYAYVNF 
        60         70         80         90        100
QQPADAERAL DTMNFDLVRN KPIRIMWSQR DPSLRRSGVG NVFIKNLDRA 
       110        120        130        140        150
IDNKAIYDTF SAFGNILSCK VATDEKGNSK GYGFVHFETE EAANTSIDKV 
       160        170        180        190        200
NGMLLNGKKV YVGKFIPRKE REKELGEKAK LFTNVYVKNF TEDFDDEKLK 
       210        220        230        240        250
EFFEPYGKIT SYKVMSKEDG KSKGFGFVAF ETTEAAEAAV QALNGKDMGE 
       260        270        280        290        300
GKSLYVARAQ KKAERQQELK RKFEELKQKR HESVFGVNLY VKNLDDTIDD 
       310        320        330        340        350
DRLRIAFSPY GNITSAKVMT DEEGRSKGFG FVCFNAASEA TCAVTELNGR 
       360        370        380        390        400
VVGSKPLYVA LAQRKEERKA HLASQYMRHM TGMRMQQLGQ IYQPNAASGF 
       410        420        430        440        450
FVPTLPSNQR FFGSQVATQM RNTPRWVPQV RPPAAIQGVQ AGAAAAGGFQ 
       460        470        480        490        500
GTAGAVPTQF RSAAAGARGA QPQVQGTHAA AAAANNMRNT GARAITGQQT 
       510        520        530        540        550
AAPNMQIPGA QIAGGAQQRT SNYKYTSNMR NPPVPQLHQT QPIPQQLQGK 
       560        570        580        590        600
NSEKLIASLL ANAKPQEQKQ ILGERLYPMI EHMHANLAGK ITGMLLEIEN 
       610        620        630 
SELLHMIEDQ EALKAKVEEA VAVLQVHRVT EPAN
Length:634
Mass (Da):69,925
Last modified:September 27, 2005 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA76B204ED206392E
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti171 – 173REK → Q in AAA70421 (PubMed:2125288).Curated3
Sequence conflicti336 – 337AA → PE in AAA70421 (PubMed:2125288).Curated2
Sequence conflicti371H → D in AAA70421 (PubMed:2125288).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
L05109 mRNA Translation: AAA70421.1
AE013599 Genomic DNA Translation: AAF57746.1
AE013599 Genomic DNA Translation: AAM68175.1
AY118528 mRNA Translation: AAM49897.1

Protein sequence database of the Protein Information Resource

More...PIRi		S30887

NCBI Reference Sequences

More...RefSeqi		NP_476667.1, NM_057319.5
NP_725749.1, NM_166264.4
NP_725750.1, NM_166265.2

Genome annotation databases

Ensembl metazoan genome annotation project

More...EnsemblMetazoai		FBtr0086736; FBpp0085915; FBgn0265297
FBtr0086738; FBpp0085917; FBgn0265297
FBtr0086740; FBpp0085919; FBgn0265297

Database of genes from NCBI RefSeq genomes

More...GeneIDi		37070

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		dme:Dmel_CG5119

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L05109 mRNA Translation: AAA70421.1
AE013599 Genomic DNA Translation: AAF57746.1
AE013599 Genomic DNA Translation: AAM68175.1
AY118528 mRNA Translation: AAM49897.1
PIRiS30887
RefSeqiNP_476667.1, NM_057319.5
NP_725749.1, NM_166264.4
NP_725750.1, NM_166265.2

3D structure databases

SMRiP21187
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi62753, 62 interactors
DIPiDIP-52140N
ELMiP21187
IntActiP21187, 18 interactors
MINTiP21187
STRINGi7227.FBpp0085915

Proteomic databases

PaxDbiP21187
PRIDEiP21187

Protocols and materials databases

ABCD curated depository of sequenced antibodies

More...ABCDi		P21187, 15 sequenced antibodies

Genome annotation databases

EnsemblMetazoaiFBtr0086736; FBpp0085915; FBgn0265297
FBtr0086738; FBpp0085917; FBgn0265297
FBtr0086740; FBpp0085919; FBgn0265297
GeneIDi37070
KEGGidme:Dmel_CG5119

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		37070
FlyBaseiFBgn0265297, pAbp

Phylogenomic databases

eggNOGiKOG0123, Eukaryota
GeneTreeiENSGT00940000169027
HOGENOMiCLU_012062_22_2_1
InParanoidiP21187
KOiK13126
OMAiMQPAVFY
OrthoDBi1027234at2759
PhylomeDBiP21187

Enzyme and pathway databases

ReactomeiR-DME-156827, L13a-mediated translational silencing of Ceruloplasmin expression
R-DME-429947, Deadenylation of mRNA
R-DME-450408, AUF1 (hnRNP D0) binds and destabilizes mRNA
R-DME-72649, Translation initiation complex formation
R-DME-975956, Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-DME-975957, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		37070, 1 hit in 5 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		pAbp, fly

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		37070

Protein Ontology

More...PROi		PR:P21187

Gene expression databases

BgeeiFBgn0265297, Expressed in cleaving embryo and 41 other tissues
GenevisibleiP21187, DM

Family and domain databases

Gene3Di3.30.70.330, 4 hits
InterProiView protein in InterPro
IPR012677, Nucleotide-bd_a/b_plait_sf
IPR036053, PABP-dom
IPR006515, PABP_1234
IPR002004, PABP_HYD
IPR035979, RBD_domain_sf
IPR000504, RRM_dom
PfamiView protein in Pfam
PF00658, PABP, 1 hit
PF00076, RRM_1, 4 hits
SMARTiView protein in SMART
SM00517, PolyA, 1 hit
SM00360, RRM, 4 hits
SUPFAMiSSF54928, SSF54928, 2 hits
SSF63570, SSF63570, 1 hit
TIGRFAMsiTIGR01628, PABP-1234, 1 hit
PROSITEiView protein in PROSITE
PS51309, PABC, 1 hit
PS50102, RRM, 4 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPABP_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P21187
Secondary accession number(s): A4UZM5, Q0E932, Q9V8C3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 1991
Last sequence update: September 27, 2005
Last modified: August 12, 2020
This is version 192 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. SIMILARITY comments
    Index of protein domains and families
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