Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

50S ribosomal protein L3

Gene

rpl3

Organism
Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L3
Alternative name(s):
Hl1
Hmal3
Gene namesi
Name:rpl3
Ordered Locus Names:rrnAC1611
OrganismiHaloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
Taxonomic identifieri272569 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaStenosarchaea groupHalobacteriaHalobacterialesHaloarculaceaeHaloarcula
Proteomesi
  • UP000001169 Componenti: Chromosome I

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved
ChainiPRO_00000772072 – 33850S ribosomal protein L3Add BLAST337

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e. Interacts weakly with protein L13.2 Publications

Protein-protein interaction databases

STRINGi272569.rrnAC1611

Structurei

Secondary structure

1338
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliP20279
SMRiP20279
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP20279

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiarCOG04070 Archaea
COG0087 LUCA
HOGENOMiHOG000107320
KOiK02906
OMAiHQRTEYN
OrthoDBiPOG093Z05KT

Family and domain databases

HAMAPiMF_01325_A Ribosomal_L3_A, 1 hit
InterProiView protein in InterPro
IPR000597 Ribosomal_L3
IPR019928 Ribosomal_L3_arc
IPR019926 Ribosomal_L3_CS
IPR009000 Transl_B-barrel_sf
PANTHERiPTHR11363:SF5 PTHR11363:SF5, 1 hit
PfamiView protein in Pfam
PF00297 Ribosomal_L3, 1 hit
SUPFAMiSSF50447 SSF50447, 1 hit
TIGRFAMsiTIGR03626 L3_arch, 1 hit
PROSITEiView protein in PROSITE
PS00474 RIBOSOMAL_L3, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P20279-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPQPSRPRKG SLGFGPRKRS TSETPRFNSW PSDDGQPGVQ GFAGYKAGMT
60 70 80 90 100
HVVLVNDEPN SPREGMEETV PVTVIETPPM RAVALRAYED TPYGQRPLTE
110 120 130 140 150
VWTDEFHSEL DRTLDVPEDH DPDAAEEQIR DAHEAGDLGD LRLITHTVPD
160 170 180 190 200
AVPSVPKKKP DVMETRVGGG SVSDRLDHAL DIVEDGGEHA MNDIFRAGEY
210 220 230 240 250
ADVAGVTKGK GTQGPVKRWG VQKRKGKHAR QGWRRRIGNL GPWNPSRVRS
260 270 280 290 300
TVPQQGQTGY HQRTELNKRL IDIGEGDEPT VDGGFVNYGE VDGPYTLVKG
310 320 330
SVPGPDKRLV RFRPAVRPND QPRLDPEVRY VSNESNQG
Length:338
Mass (Da):37,341
Last modified:January 23, 2007 - v5
Checksum:i996D3BE503F4DBD4
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti311R → P in AAA86859 (PubMed:2406244).Curated1
Sequence conflicti312F → FF AA sequence (PubMed:2406244).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J05222 Genomic DNA Translation: AAA86859.1
AY596297 Genomic DNA Translation: AAV46528.1
PIRiC35063 R5HS3L
RefSeqiWP_004957423.1, NC_006396.1

Genome annotation databases

EnsemblBacteriaiAAV46528; AAV46528; rrnAC1611
GeneIDi3128366
KEGGihma:rrnAC1611
PATRICifig|272569.17.peg.2301

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J05222 Genomic DNA Translation: AAA86859.1
AY596297 Genomic DNA Translation: AAV46528.1
PIRiC35063 R5HS3L
RefSeqiWP_004957423.1, NC_006396.1

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1FFKX-ray2.40B2-338[»]
1JJ2X-ray2.40B2-338[»]
1K73X-ray3.01D2-338[»]
1K8AX-ray3.00D2-338[»]
1K9MX-ray3.00D2-338[»]
1KC8X-ray3.01D2-338[»]
1KD1X-ray3.00D2-338[»]
1KQSX-ray3.10B2-338[»]
1M1KX-ray3.20D2-338[»]
1M90X-ray2.80D2-338[»]
1ML5electron microscopy14.00e2-311[»]
e312-338[»]
1N8RX-ray3.00D2-338[»]
1NJIX-ray3.00D2-338[»]
1Q7YX-ray3.20D2-338[»]
1Q81X-ray2.95D2-338[»]
1Q82X-ray2.98D2-338[»]
1Q86X-ray3.00D2-338[»]
1QVFX-ray3.10B2-338[»]
1QVGX-ray2.90B2-338[»]
1S72X-ray2.40B1-338[»]
1VQ4X-ray2.70B1-338[»]
1VQ5X-ray2.60B1-338[»]
1VQ6X-ray2.70B1-338[»]
1VQ7X-ray2.50B1-338[»]
1VQ8X-ray2.20B1-338[»]
1VQ9X-ray2.40B1-338[»]
1VQKX-ray2.30B1-338[»]
1VQLX-ray2.30B1-338[»]
1VQMX-ray2.30B1-338[»]
1VQNX-ray2.40B1-338[»]
1VQOX-ray2.20B1-338[»]
1VQPX-ray2.25B1-338[»]
1W2BX-ray3.50B2-338[»]
1YHQX-ray2.40B1-338[»]
1YI2X-ray2.65B1-338[»]
1YIJX-ray2.60B1-338[»]
1YITX-ray2.80B1-338[»]
1YJ9X-ray2.90B1-338[»]
1YJNX-ray3.00B1-338[»]
1YJWX-ray2.90B1-338[»]
2OTJX-ray2.90B1-338[»]
2OTLX-ray2.70B2-338[»]
2QA4X-ray3.00B1-338[»]
2QEXX-ray2.90B1-338[»]
3CC2X-ray2.40B1-338[»]
3CC4X-ray2.70B1-338[»]
3CC7X-ray2.70B1-338[»]
3CCEX-ray2.75B1-338[»]
3CCJX-ray2.70B1-338[»]
3CCLX-ray2.90B1-338[»]
3CCMX-ray2.55B1-338[»]
3CCQX-ray2.90B1-338[»]
3CCRX-ray3.00B1-338[»]
3CCSX-ray2.95B1-338[»]
3CCUX-ray2.80B1-338[»]
3CCVX-ray2.90B1-338[»]
3CD6X-ray2.75B1-338[»]
3CMAX-ray2.80B1-338[»]
3CMEX-ray2.95B1-338[»]
3CPWX-ray2.70B1-338[»]
3CXCX-ray3.00B2-338[»]
3G4SX-ray3.20B2-338[»]
3G6EX-ray2.70B2-338[»]
3G71X-ray2.85B2-338[»]
3I55X-ray3.11B1-338[»]
3I56X-ray2.90B1-338[»]
3OW2X-ray2.70B2-338[»]
4ADXelectron microscopy6.60B1-338[»]
4V4TX-ray6.46E2-338[»]
4V9FX-ray2.40B1-338[»]
ProteinModelPortaliP20279
SMRiP20279
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272569.rrnAC1611

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAV46528; AAV46528; rrnAC1611
GeneIDi3128366
KEGGihma:rrnAC1611
PATRICifig|272569.17.peg.2301

Phylogenomic databases

eggNOGiarCOG04070 Archaea
COG0087 LUCA
HOGENOMiHOG000107320
KOiK02906
OMAiHQRTEYN
OrthoDBiPOG093Z05KT

Miscellaneous databases

EvolutionaryTraceiP20279

Family and domain databases

HAMAPiMF_01325_A Ribosomal_L3_A, 1 hit
InterProiView protein in InterPro
IPR000597 Ribosomal_L3
IPR019928 Ribosomal_L3_arc
IPR019926 Ribosomal_L3_CS
IPR009000 Transl_B-barrel_sf
PANTHERiPTHR11363:SF5 PTHR11363:SF5, 1 hit
PfamiView protein in Pfam
PF00297 Ribosomal_L3, 1 hit
SUPFAMiSSF50447 SSF50447, 1 hit
TIGRFAMsiTIGR03626 L3_arch, 1 hit
PROSITEiView protein in PROSITE
PS00474 RIBOSOMAL_L3, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiRL3_HALMA
AccessioniPrimary (citable) accession number: P20279
Secondary accession number(s): Q5V1S4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1991
Last sequence update: January 23, 2007
Last modified: October 10, 2018
This is version 128 of the entry and version 5 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again