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UniProtKB - P20279 (RL3_HALMA)

Entry version 130 (08 May 2019)
Sequence version 5 (23 Jan 2007)
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Protein

50S ribosomal protein L3

Gene

rpl3

Organism
Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
50S ribosomal protein L3
Alternative name(s):
Hl1
Hmal3
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:rpl3
Ordered Locus Names:rrnAC1611
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHaloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri272569 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiArchaea › Euryarchaeota › Stenosarchaea group › Halobacteria › Halobacteriales › Haloarculaceae › Haloarcula ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001169 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome I

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

GO - Cellular componenti

Complete GO annotation on QuickGO ...

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemoved
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000772072 – 33850S ribosomal protein L3Add BLAST337

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Part of the 50S ribosomal subunit.

Forms a cluster with proteins L14 and L24e.

Interacts weakly with protein L13.

2 Publications

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		272569.rrnAC1611

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1338
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P20279

Database of comparative protein structure models

More...ModBasei		Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...EvolutionaryTracei		P20279

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the universal ribosomal protein uL3 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		arCOG04070 Archaea
COG0087 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		HOG000107320

KEGG Orthology (KO)

More...KOi		K02906

Identification of Orthologs from Complete Genome Data

More...OMAi		HQRTEYN

Database of Orthologous Groups

More...OrthoDBi		31722at2157

Family and domain databases

HAMAP database of protein families

More...HAMAPi		MF_01325_A Ribosomal_L3_A, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000597 Ribosomal_L3
IPR019928 Ribosomal_L3_arc
IPR019926 Ribosomal_L3_CS
IPR009000 Transl_B-barrel_sf

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00297 Ribosomal_L3, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF50447 SSF50447, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR03626 L3_arch, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00474 RIBOSOMAL_L3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

P20279-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPQPSRPRKG SLGFGPRKRS TSETPRFNSW PSDDGQPGVQ GFAGYKAGMT 
        60         70         80         90        100
HVVLVNDEPN SPREGMEETV PVTVIETPPM RAVALRAYED TPYGQRPLTE 
       110        120        130        140        150
VWTDEFHSEL DRTLDVPEDH DPDAAEEQIR DAHEAGDLGD LRLITHTVPD 
       160        170        180        190        200
AVPSVPKKKP DVMETRVGGG SVSDRLDHAL DIVEDGGEHA MNDIFRAGEY 
       210        220        230        240        250
ADVAGVTKGK GTQGPVKRWG VQKRKGKHAR QGWRRRIGNL GPWNPSRVRS 
       260        270        280        290        300
TVPQQGQTGY HQRTELNKRL IDIGEGDEPT VDGGFVNYGE VDGPYTLVKG 
       310        320        330 
SVPGPDKRLV RFRPAVRPND QPRLDPEVRY VSNESNQG
Length:338
Mass (Da):37,341
Last modified:January 23, 2007 - v5
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i996D3BE503F4DBD4
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti311R → P in AAA86859 (PubMed:2406244).Curated1
Sequence conflicti312F → FF AA sequence (PubMed:2406244).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
J05222 Genomic DNA Translation: AAA86859.1
AY596297 Genomic DNA Translation: AAV46528.1

Protein sequence database of the Protein Information Resource

More...PIRi		C35063 R5HS3L

NCBI Reference Sequences

More...RefSeqi		WP_004957423.1, NC_006396.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...EnsemblBacteriai		AAV46528; AAV46528; rrnAC1611

Database of genes from NCBI RefSeq genomes

More...GeneIDi		3128366

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hma:rrnAC1611

Pathosystems Resource Integration Center (PATRIC)

More...PATRICi		fig|272569.17.peg.2301

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J05222 Genomic DNA Translation: AAA86859.1
AY596297 Genomic DNA Translation: AAV46528.1
PIRiC35063 R5HS3L
RefSeqiWP_004957423.1, NC_006396.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1FFKX-ray2.40B2-338[»]
1JJ2X-ray2.40B2-338[»]
1K73X-ray3.01D2-338[»]
1K8AX-ray3.00D2-338[»]
1K9MX-ray3.00D2-338[»]
1KC8X-ray3.01D2-338[»]
1KD1X-ray3.00D2-338[»]
1KQSX-ray3.10B2-338[»]
1M1KX-ray3.20D2-338[»]
1M90X-ray2.80D2-338[»]
1ML5electron microscopy14.00e2-311[»]
e312-338[»]
1N8RX-ray3.00D2-338[»]
1NJIX-ray3.00D2-338[»]
1Q7YX-ray3.20D2-338[»]
1Q81X-ray2.95D2-338[»]
1Q82X-ray2.98D2-338[»]
1Q86X-ray3.00D2-338[»]
1QVFX-ray3.10B2-338[»]
1QVGX-ray2.90B2-338[»]
1S72X-ray2.40B1-338[»]
1VQ4X-ray2.70B1-338[»]
1VQ5X-ray2.60B1-338[»]
1VQ6X-ray2.70B1-338[»]
1VQ7X-ray2.50B1-338[»]
1VQ8X-ray2.20B1-338[»]
1VQ9X-ray2.40B1-338[»]
1VQKX-ray2.30B1-338[»]
1VQLX-ray2.30B1-338[»]
1VQMX-ray2.30B1-338[»]
1VQNX-ray2.40B1-338[»]
1VQOX-ray2.20B1-338[»]
1VQPX-ray2.25B1-338[»]
1W2BX-ray3.50B2-338[»]
1YHQX-ray2.40B1-338[»]
1YI2X-ray2.65B1-338[»]
1YIJX-ray2.60B1-338[»]
1YITX-ray2.80B1-338[»]
1YJ9X-ray2.90B1-338[»]
1YJNX-ray3.00B1-338[»]
1YJWX-ray2.90B1-338[»]
2OTJX-ray2.90B1-338[»]
2OTLX-ray2.70B2-338[»]
2QA4X-ray3.00B1-338[»]
2QEXX-ray2.90B1-338[»]
3CC2X-ray2.40B1-338[»]
3CC4X-ray2.70B1-338[»]
3CC7X-ray2.70B1-338[»]
3CCEX-ray2.75B1-338[»]
3CCJX-ray2.70B1-338[»]
3CCLX-ray2.90B1-338[»]
3CCMX-ray2.55B1-338[»]
3CCQX-ray2.90B1-338[»]
3CCRX-ray3.00B1-338[»]
3CCSX-ray2.95B1-338[»]
3CCUX-ray2.80B1-338[»]
3CCVX-ray2.90B1-338[»]
3CD6X-ray2.75B1-338[»]
3CMAX-ray2.80B1-338[»]
3CMEX-ray2.95B1-338[»]
3CPWX-ray2.70B1-338[»]
3CXCX-ray3.00B2-338[»]
3G4SX-ray3.20B2-338[»]
3G6EX-ray2.70B2-338[»]
3G71X-ray2.85B2-338[»]
3I55X-ray3.11B1-338[»]
3I56X-ray2.90B1-338[»]
3OW2X-ray2.70B2-338[»]
4ADXelectron microscopy6.60B1-338[»]
4V4TX-ray6.46E2-338[»]
4V9FX-ray2.40B1-338[»]
SMRiP20279
ModBaseiSearch...

Protein-protein interaction databases

STRINGi272569.rrnAC1611

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAV46528; AAV46528; rrnAC1611
GeneIDi3128366
KEGGihma:rrnAC1611
PATRICifig|272569.17.peg.2301

Phylogenomic databases

eggNOGiarCOG04070 Archaea
COG0087 LUCA
HOGENOMiHOG000107320
KOiK02906
OMAiHQRTEYN
OrthoDBi31722at2157

Miscellaneous databases

EvolutionaryTraceiP20279

Family and domain databases

HAMAPiMF_01325_A Ribosomal_L3_A, 1 hit
InterProiView protein in InterPro
IPR000597 Ribosomal_L3
IPR019928 Ribosomal_L3_arc
IPR019926 Ribosomal_L3_CS
IPR009000 Transl_B-barrel_sf
PfamiView protein in Pfam
PF00297 Ribosomal_L3, 1 hit
SUPFAMiSSF50447 SSF50447, 1 hit
TIGRFAMsiTIGR03626 L3_arch, 1 hit
PROSITEiView protein in PROSITE
PS00474 RIBOSOMAL_L3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRL3_HALMA
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P20279
Secondary accession number(s): Q5V1S4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1991
Last sequence update: January 23, 2007
Last modified: May 8, 2019
This is version 130 of the entry and version 5 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Ribosomal proteins
    Ribosomal proteins families and list of entries
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