UniProtKB - P20279 (RL3_HALMA)
Protein
50S ribosomal protein L3
Gene
rpl3
Organism
Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
Status
Functioni
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.By similarity
GO - Molecular functioni
- rRNA binding Source: UniProtKB-UniRule
- structural constituent of ribosome Source: InterPro
GO - Biological processi
- translation Source: UniProtKB-UniRule
Keywordsi
Molecular function | Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding |
Names & Taxonomyi
Protein namesi | Recommended name: 50S ribosomal protein L3Alternative name(s): Hl1 Hmal3 |
Gene namesi | Name:rpl3 Ordered Locus Names:rrnAC1611 |
Organismi | Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui) |
Taxonomic identifieri | 272569 [NCBI] |
Taxonomic lineagei | Archaea › Euryarchaeota › Stenosarchaea group › Halobacteria › Halobacteriales › Haloarculaceae › Haloarcula › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Initiator methioninei | Removed | |||
ChainiPRO_0000077207 | 2 – 338 | 50S ribosomal protein L3Add BLAST | 337 |
Interactioni
Subunit structurei
Part of the 50S ribosomal subunit.
Forms a cluster with proteins L14 and L24e.
Interacts weakly with protein L13.
2 PublicationsProtein-protein interaction databases
STRINGi | 272569.rrnAC1611 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | P20279 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P20279 |
Family & Domainsi
Sequence similaritiesi
Belongs to the universal ribosomal protein uL3 family.Curated
Phylogenomic databases
eggNOGi | arCOG04070, Archaea |
HOGENOMi | CLU_033361_2_0_2 |
OMAi | HQRTEYN |
Family and domain databases
HAMAPi | MF_01325_A, Ribosomal_L3_A, 1 hit |
InterProi | View protein in InterPro IPR000597, Ribosomal_L3 IPR019928, Ribosomal_L3_arc IPR019926, Ribosomal_L3_CS IPR009000, Transl_B-barrel_sf |
Pfami | View protein in Pfam PF00297, Ribosomal_L3, 1 hit |
SUPFAMi | SSF50447, SSF50447, 1 hit |
TIGRFAMsi | TIGR03626, L3_arch, 1 hit |
PROSITEi | View protein in PROSITE PS00474, RIBOSOMAL_L3, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P20279-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPQPSRPRKG SLGFGPRKRS TSETPRFNSW PSDDGQPGVQ GFAGYKAGMT
60 70 80 90 100
HVVLVNDEPN SPREGMEETV PVTVIETPPM RAVALRAYED TPYGQRPLTE
110 120 130 140 150
VWTDEFHSEL DRTLDVPEDH DPDAAEEQIR DAHEAGDLGD LRLITHTVPD
160 170 180 190 200
AVPSVPKKKP DVMETRVGGG SVSDRLDHAL DIVEDGGEHA MNDIFRAGEY
210 220 230 240 250
ADVAGVTKGK GTQGPVKRWG VQKRKGKHAR QGWRRRIGNL GPWNPSRVRS
260 270 280 290 300
TVPQQGQTGY HQRTELNKRL IDIGEGDEPT VDGGFVNYGE VDGPYTLVKG
310 320 330
SVPGPDKRLV RFRPAVRPND QPRLDPEVRY VSNESNQG
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 311 | R → P in AAA86859 (PubMed:2406244).Curated | 1 | |
Sequence conflicti | 312 | F → FF AA sequence (PubMed:2406244).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | J05222 Genomic DNA Translation: AAA86859.1 AY596297 Genomic DNA Translation: AAV46528.1 |
PIRi | C35063, R5HS3L |
RefSeqi | WP_004957423.1, NZ_CP039138.1 |
Genome annotation databases
EnsemblBacteriai | AAV46528; AAV46528; rrnAC1611 |
GeneIDi | 40152577 |
KEGGi | hma:rrnAC1611 |
PATRICi | fig|272569.17.peg.2301 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | J05222 Genomic DNA Translation: AAA86859.1 AY596297 Genomic DNA Translation: AAV46528.1 |
PIRi | C35063, R5HS3L |
RefSeqi | WP_004957423.1, NZ_CP039138.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1FFK | X-ray | 2.40 | B | 2-338 | [»] | |
1JJ2 | X-ray | 2.40 | B | 2-338 | [»] | |
1K73 | X-ray | 3.01 | D | 2-338 | [»] | |
1K8A | X-ray | 3.00 | D | 2-338 | [»] | |
1K9M | X-ray | 3.00 | D | 2-338 | [»] | |
1KC8 | X-ray | 3.01 | D | 2-338 | [»] | |
1KD1 | X-ray | 3.00 | D | 2-338 | [»] | |
1KQS | X-ray | 3.10 | B | 2-338 | [»] | |
1M1K | X-ray | 3.20 | D | 2-338 | [»] | |
1M90 | X-ray | 2.80 | D | 2-338 | [»] | |
1ML5 | electron microscopy | 14.00 | e | 2-311 | [»] | |
e | 312-338 | [»] | ||||
1N8R | X-ray | 3.00 | D | 2-338 | [»] | |
1NJI | X-ray | 3.00 | D | 2-338 | [»] | |
1Q7Y | X-ray | 3.20 | D | 2-338 | [»] | |
1Q81 | X-ray | 2.95 | D | 2-338 | [»] | |
1Q82 | X-ray | 2.98 | D | 2-338 | [»] | |
1Q86 | X-ray | 3.00 | D | 2-338 | [»] | |
1QVF | X-ray | 3.10 | B | 2-338 | [»] | |
1QVG | X-ray | 2.90 | B | 2-338 | [»] | |
1S72 | X-ray | 2.40 | B | 1-338 | [»] | |
1VQ4 | X-ray | 2.70 | B | 1-338 | [»] | |
1VQ5 | X-ray | 2.60 | B | 1-338 | [»] | |
1VQ6 | X-ray | 2.70 | B | 1-338 | [»] | |
1VQ7 | X-ray | 2.50 | B | 1-338 | [»] | |
1VQ8 | X-ray | 2.20 | B | 1-338 | [»] | |
1VQ9 | X-ray | 2.40 | B | 1-338 | [»] | |
1VQK | X-ray | 2.30 | B | 1-338 | [»] | |
1VQL | X-ray | 2.30 | B | 1-338 | [»] | |
1VQM | X-ray | 2.30 | B | 1-338 | [»] | |
1VQN | X-ray | 2.40 | B | 1-338 | [»] | |
1VQO | X-ray | 2.20 | B | 1-338 | [»] | |
1VQP | X-ray | 2.25 | B | 1-338 | [»] | |
1W2B | X-ray | 3.50 | B | 2-338 | [»] | |
1YHQ | X-ray | 2.40 | B | 1-338 | [»] | |
1YI2 | X-ray | 2.65 | B | 1-338 | [»] | |
1YIJ | X-ray | 2.60 | B | 1-338 | [»] | |
1YIT | X-ray | 2.80 | B | 1-338 | [»] | |
1YJ9 | X-ray | 2.90 | B | 1-338 | [»] | |
1YJN | X-ray | 3.00 | B | 1-338 | [»] | |
1YJW | X-ray | 2.90 | B | 1-338 | [»] | |
2OTJ | X-ray | 2.90 | B | 1-338 | [»] | |
2OTL | X-ray | 2.70 | B | 2-338 | [»] | |
2QA4 | X-ray | 3.00 | B | 1-338 | [»] | |
2QEX | X-ray | 2.90 | B | 1-338 | [»] | |
3CC2 | X-ray | 2.40 | B | 1-338 | [»] | |
3CC4 | X-ray | 2.70 | B | 1-338 | [»] | |
3CC7 | X-ray | 2.70 | B | 1-338 | [»] | |
3CCE | X-ray | 2.75 | B | 1-338 | [»] | |
3CCJ | X-ray | 2.70 | B | 1-338 | [»] | |
3CCL | X-ray | 2.90 | B | 1-338 | [»] | |
3CCM | X-ray | 2.55 | B | 1-338 | [»] | |
3CCQ | X-ray | 2.90 | B | 1-338 | [»] | |
3CCR | X-ray | 3.00 | B | 1-338 | [»] | |
3CCS | X-ray | 2.95 | B | 1-338 | [»] | |
3CCU | X-ray | 2.80 | B | 1-338 | [»] | |
3CCV | X-ray | 2.90 | B | 1-338 | [»] | |
3CD6 | X-ray | 2.75 | B | 1-338 | [»] | |
3CMA | X-ray | 2.80 | B | 1-338 | [»] | |
3CME | X-ray | 2.95 | B | 1-338 | [»] | |
3CPW | X-ray | 2.70 | B | 1-338 | [»] | |
3CXC | X-ray | 3.00 | B | 2-338 | [»] | |
3G4S | X-ray | 3.20 | B | 2-338 | [»] | |
3G6E | X-ray | 2.70 | B | 2-338 | [»] | |
3G71 | X-ray | 2.85 | B | 2-338 | [»] | |
3I55 | X-ray | 3.11 | B | 1-338 | [»] | |
3I56 | X-ray | 2.90 | B | 1-338 | [»] | |
3OW2 | X-ray | 2.70 | B | 2-338 | [»] | |
4ADX | electron microscopy | 6.60 | B | 1-338 | [»] | |
4V42 | X-ray | 5.50 | BE | 2-338 | [»] | |
4V4R | X-ray | 5.90 | BE | 2-338 | [»] | |
4V4S | X-ray | 6.76 | BE | 2-338 | [»] | |
4V4T | X-ray | 6.46 | E | 2-338 | [»] | |
4V9F | X-ray | 2.40 | B | 1-338 | [»] | |
SMRi | P20279 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
STRINGi | 272569.rrnAC1611 |
Genome annotation databases
EnsemblBacteriai | AAV46528; AAV46528; rrnAC1611 |
GeneIDi | 40152577 |
KEGGi | hma:rrnAC1611 |
PATRICi | fig|272569.17.peg.2301 |
Phylogenomic databases
eggNOGi | arCOG04070, Archaea |
HOGENOMi | CLU_033361_2_0_2 |
OMAi | HQRTEYN |
Miscellaneous databases
EvolutionaryTracei | P20279 |
Family and domain databases
HAMAPi | MF_01325_A, Ribosomal_L3_A, 1 hit |
InterProi | View protein in InterPro IPR000597, Ribosomal_L3 IPR019928, Ribosomal_L3_arc IPR019926, Ribosomal_L3_CS IPR009000, Transl_B-barrel_sf |
Pfami | View protein in Pfam PF00297, Ribosomal_L3, 1 hit |
SUPFAMi | SSF50447, SSF50447, 1 hit |
TIGRFAMsi | TIGR03626, L3_arch, 1 hit |
PROSITEi | View protein in PROSITE PS00474, RIBOSOMAL_L3, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | RL3_HALMA | |
Accessioni | P20279Primary (citable) accession number: P20279 Secondary accession number(s): Q5V1S4 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 1, 1991 |
Last sequence update: | January 23, 2007 | |
Last modified: | April 7, 2021 | |
This is version 140 of the entry and version 5 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencing, Reference proteomeDocuments
- Ribosomal proteins
Ribosomal proteins families and list of entries - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families