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UniProtKB - P20214 (VINT_SSV1)
Protein
Integrase
Gene
d335
Organism
Sulfolobus spindle-shape virus 1 (SSV1)
Status
Functioni
This protein may encode a site-specific integrase, which is necessary for integration of the phage by site-specific recombination into a tRNA gene of the host chromosome. Essential for virus infection.
2 PublicationsSites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 211 | PROSITE-ProRule annotation | 1 | |
Active sitei | 281 | PROSITE-ProRule annotation | 1 | |
Active sitei | 314 | O-(3'-phospho-DNA)-tyrosine intermediatePROSITE-ProRule annotation | 1 |
GO - Molecular functioni
- DNA binding Source: UniProtKB-KW
- hydrolase activity Source: UniProtKB-KW
- transferase activity Source: UniProtKB-KW
GO - Biological processi
- DNA integration Source: UniProtKB-KW
- DNA recombination Source: UniProtKB-KW
- establishment of integrated proviral latency Source: UniProtKB-KW
- viral entry into host cell Source: UniProtKB-KW
- viral genome integration into host DNA Source: UniProtKB-KW
Keywordsi
Molecular function | DNA-binding, Hydrolase, Transferase |
Biological process | DNA integration, DNA recombination, Viral genome integration, Virus entry into host cell |
Names & Taxonomyi
Protein namesi | |
Gene namesi | ORF Names:d335 |
Organismi | Sulfolobus spindle-shape virus 1 (SSV1) |
Taxonomic identifieri | 244589 [NCBI] |
Taxonomic lineagei | Viruses › Fuselloviridae › Alphafusellovirus |
Virus hosti | Saccharolobus solfataricus (Sulfolobus solfataricus) [TaxID: 2287] |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000197509 | 1 – 335 | IntegraseAdd BLAST | 335 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | P20214 |
ModBasei | Search... |
PDBe-KBi | Search... |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 97 – 189 | Core-binding (CB)PROSITE-ProRule annotationAdd BLAST | 93 | |
Domaini | 174 – 329 | Tyr recombinasePROSITE-ProRule annotationAdd BLAST | 156 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 62 – 82 | DisorderedSequence analysisAdd BLAST | 21 |
Sequence similaritiesi
Belongs to the 'phage' integrase family.Curated
Family and domain databases
Gene3Di | 1.10.443.10, 1 hit |
InterProi | View protein in InterPro IPR044068, CB IPR011010, DNA_brk_join_enz IPR013762, Integrase-like_cat_sf IPR002104, Integrase_catalytic IPR031857, Integrase_SSV1_C IPR012922, ORF_D-335 |
Pfami | View protein in Pfam PF16795, Phage_integr_3, 1 hit PF07935, SSV1_ORF_D-335, 1 hit |
SUPFAMi | SSF56349, SSF56349, 1 hit |
PROSITEi | View protein in PROSITE PS51900, CB, 1 hit PS51898, TYR_RECOMBINASE, 1 hit |
i Sequence
Sequence statusi: Complete.
P20214-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTKDKTRYKY GDYILRERKG RYYVYKLEYE NGEVKERYVG PLADVVESYL
60 70 80 90 100
KMKLGVVGDT PLQADPPGFE PGTSGSGGGK EGTERRKIAL VANLRQYATD
110 120 130 140 150
GNIKAFYDYL MNERGISEKT AKDYINAISK PYKETRDAQK AYRLFARFLA
160 170 180 190 200
SRNIIHDEFA DKILKAVKVK KANADIYIPT LEEIKRTLQL AKDYSENVYF
210 220 230 240 250
IYRIALESGV RLSEILKVLK EPERDICGND VCYYPLSWTR GYKGVFYVFH
260 270 280 290 300
ITPLKRVEVT KWAIADFERR HKDAIAIKYF RKFVASKMAE LSVPLDIIDF
310 320 330
IQGRKPTRVL TQHYVSLFGI AKEQYKKYAE WLKGV
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X07234 Genomic DNA Translation: CAA30211.1 |
PIRi | S03212 |
RefSeqi | NP_039778.1, NC_001338.1 |
Genome annotation databases
GeneIDi | 2559644 |
KEGGi | vg:2559644 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X07234 Genomic DNA Translation: CAA30211.1 |
PIRi | S03212 |
RefSeqi | NP_039778.1, NC_001338.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
3UXU | X-ray | 2.71 | A | 173-335 | [»] | |
3VCF | X-ray | 2.70 | A/B | 174-335 | [»] | |
4DKS | X-ray | 2.70 | A | 174-335 | [»] | |
SMRi | P20214 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Genome annotation databases
GeneIDi | 2559644 |
KEGGi | vg:2559644 |
Family and domain databases
Gene3Di | 1.10.443.10, 1 hit |
InterProi | View protein in InterPro IPR044068, CB IPR011010, DNA_brk_join_enz IPR013762, Integrase-like_cat_sf IPR002104, Integrase_catalytic IPR031857, Integrase_SSV1_C IPR012922, ORF_D-335 |
Pfami | View protein in Pfam PF16795, Phage_integr_3, 1 hit PF07935, SSV1_ORF_D-335, 1 hit |
SUPFAMi | SSF56349, SSF56349, 1 hit |
PROSITEi | View protein in PROSITE PS51900, CB, 1 hit PS51898, TYR_RECOMBINASE, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | VINT_SSV1 | |
Accessioni | P20214Primary (citable) accession number: P20214 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 1, 1991 |
Last sequence update: | February 1, 1991 | |
Last modified: | February 23, 2022 | |
This is version 99 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Viral Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families