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UniProtKB - P20099 (BISC_ECOLI)

Protein

Biotin sulfoxide reductase

Gene

bisC

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

This enzyme may serve as a scavenger, allowing the cell to utilize biotin sulfoxide as a biotin source. It reduces a spontaneous oxidation product of biotin, D-biotin D-sulfoxide (BSO or BDS), back to biotin. Also exhibits methionine-(S)-sulfoxide (Met-S-SO) reductase activity, acting specifically on the (S) enantiomer in the free, but not the protein-bound form. It thus plays a role in assimilation of oxidized methionines.2 Publications

Miscellaneous

Requires a small thioredoxin-like protein for activity.

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the ‘Function’ section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Mo-bis(molybdopterin guanine dinucleotide)2 PublicationsNote: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.2 Publications

<p>This subsection of the ‘Function’ section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

kcat is 3.2 min(-1) for the reduction of Met-S-SO using benzyl viologen as an artificial electron donor.
  1. KM=17 µM for L-methionine (S)-S-oxide1 Publication

    Sites

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘Function’ section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi148MolybdenumBy similarity1

    <p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

    • electron transfer activity Source: GO_Central
    • L-methionine:thioredoxin-disulfide S-oxidoreductase activity Source: EcoCyc
    • molybdenum ion binding Source: EcoCyc
    • molybdopterin cofactor binding Source: InterPro
    View the complete GO annotation on QuickGO ...

    GO - Biological processi

    View the complete GO annotation on QuickGO ...

    <p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

    Molecular functionOxidoreductase
    LigandMetal-binding, Molybdenum

    Enzyme and pathway databases

    BioCyc Collection of Pathway/Genome Databases

    More...    BioCyci    		EcoCyc:EG10124-MONOMER
    MetaCyc:EG10124-MONOMER

    SABIO-RK: Biochemical Reaction Kinetics Database

    More...    SABIO-RKi    		P20099

    Protein family/group databases

    Transport Classification Database

    More...    TCDBi    		5.A.3.4.3 the prokaryotic molybdopterin-containing oxidoreductase (pmo) family

    <p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
    Recommended name:
    Biotin sulfoxide reductase (EC:1.-.-.-)
    Short name:
    BDS reductase
    Short name:
    BSO reductase
    Alternative name(s):
    L-methionine-(S)-sulfoxide reductase (EC:1.8.4.13)
    Short name:
    Met-S-SO reductase
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
    Name:bisC
    Ordered Locus Names:b3551, JW5940
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coli (strain K12)
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri83333 [NCBI]
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia ›
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
    • UP000000318 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome
    • UP000000625 Componenti: Chromosome

    Organism-specific databases

    Escherichia coli strain K12 genome database

    More...    EcoGenei    		EG10124 bisC

    <p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

    GO - Cellular componenti

    View the complete GO annotation on QuickGO ...

    <p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

    <p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

    Cells lacking this gene together with metB1, msrA and msrB are unable to use Met-S-SO for growth but retain the ability to use the enantiomer Met-R-SO, while a metB1/msrA/msrB deletion mutant is able to use both compounds.1 Publication

    <p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

    Molecule processing

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000632191 – 777Biotin sulfoxide reductaseAdd BLAST777

    Proteomic databases

    jPOST - Japan Proteome Standard Repository/Database

    More...    jPOSTi    		P20099

    PaxDb, a database of protein abundance averages across all three domains of life

    More...    PaxDbi    		P20099

    PRoteomics IDEntifications database

    More...    PRIDEi    		P20099

    <p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

    Protein-protein interaction databases

    The Biological General Repository for Interaction Datasets (BioGrid)

    More...    BioGridi    		4261247, 8 interactors

    STRING: functional protein association networks

    More...    STRINGi    		316385.ECDH10B_3730

    <p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

    3D structure databases

    Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

    More...    ProteinModelPortali    		P20099

    SWISS-MODEL Repository - a database of annotated 3D protein structure models

    More...    SMRi    		P20099

    Database of comparative protein structure models

    More...    ModBasei    		Search...

    MobiDB: a database of protein disorder and mobility annotations

    More...    MobiDBi    		Search...

    <p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

    <p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

    The N-terminal 39 residues are essential for activity.1 Publication

    <p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

    Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.Curated

    Phylogenomic databases

    evolutionary genealogy of genes: Non-supervised Orthologous Groups

    More...    eggNOGi    		ENOG4107QY8 Bacteria
    COG0243 LUCA

    The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

    More...    HOGENOMi    		HOG000284391

    InParanoid: Eukaryotic Ortholog Groups

    More...    InParanoidi    		P20099

    KEGG Orthology (KO)

    More...    KOi    		K08351

    Database for complete collections of gene phylogenies

    More...    PhylomeDBi    		P20099

    Family and domain databases

    Integrated resource of protein families, domains and functional sites

    More...    InterProi    		View protein in InterPro
    IPR009010 Asp_de-COase-like_dom_sf
    IPR006658 BisC
    IPR006657 MoPterin_dinucl-bd_dom
    IPR006656 Mopterin_OxRdtase
    IPR006655 Mopterin_OxRdtase_prok_CS

    Pfam protein domain database

    More...    Pfami    		View protein in Pfam
    PF00384 Molybdopterin, 1 hit
    PF01568 Molydop_binding, 1 hit

    Superfamily database of structural and functional annotation

    More...    SUPFAMi    		SSF50692 SSF50692, 1 hit

    TIGRFAMs; a protein family database

    More...    TIGRFAMsi    		TIGR00509 bisC_fam, 1 hit

    PROSITE; a protein domain and family database

    More...    PROSITEi    		View protein in PROSITE
    PS00490 MOLYBDOPTERIN_PROK_2, 1 hit
    PS00932 MOLYBDOPTERIN_PROK_3, 1 hit

    <p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

    P20099-1 [UniParc]FASTAAdd to basket
    « Hide
            10         20         30         40         50
    MANSSSRYSV LTAAHWGPML VETDGETVFS SRGALATGME NSLQSAVRDQ 
            60         70         80         90        100
    VHSNTRVRFP MVRKGFLASP ENPQGIRGQD EFVRVSWDEA LDLIHQQHKR 
           110        120        130        140        150
    IREAYGPASI FAGSYGWRSN GVLHKASTLL QRYMALAGGY TGHLGDYSTG 
           160        170        180        190        200
    AAQAIMPYVV GGSEVYQQQT SWPLVLEHSD VVVLWSANPL NTLKIAWNAS 
           210        220        230        240        250
    DEQGLSYFSA LRDSGKKLIC IDPMRSETVD FFGDKMEWVA PHMGTDVALM 
           260        270        280        290        300
    LGIAHTLVEN GWHDEAFLAR CTTGYAVFAS YLLGESDGIA KTAEWAAEIC 
           310        320        330        340        350
    GVGAAKIREL AAIFHQNTTM LMAGWGMQRQ QFGEQKHWMI VTLAAMLGQI 
           360        370        380        390        400
    GTPGGGFGLS YHFANGGNPT RRSAVLSSMQ GSLPGGCDAV DKIPVARIVE 
           410        420        430        440        450
    ALENPGGAYQ HNGMNRHFPD IRFIWWAGGA NFTHHQDTNR LIRAWQKPEL 
           460        470        480        490        500
    VVISECFWTA AAKHADIVLP ATTSFERNDL TMTGDYSNQH LVPMKQVVPP 
           510        520        530        540        550
    RYEARNDFDV FAELSERWEK GGYARFTEGK SELQWLETFY NVARQRGASQ 
           560        570        580        590        600
    QVELPPFAEF WQANQLIEMP ENPDSERFIR FADFCRDPLA HPLKTASGKI 
           610        620        630        640        650
    EIFSQRIADY GYPDCPGHPM WLEPDEWQGN AEPEQLQVLS AHPAHRLHSQ 
           660        670        680        690        700
    LNYSSLRELY AVANREPVTI HPDDAQERGI QDGDTVRLWN ARGQILAGAV 
           710        720        730        740        750
    ISEGIKPGVI CIHEGAWPDL DLTADGICKN GAVNVLTKDL PSSRLGNGCA 
           760        770 
    GNTALAWLEK YNGPELTLTA FEPPASS
    Length:777
    Mass (Da):85,851
    Last modified:May 30, 2000 - v3
    <p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i51087D957E4FB38B
    GO

    <p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

    The sequence AAB18528 differs from that shown. Reason: Erroneous initiation.Curated
    The sequence BAE77744 differs from that shown. Reason: Erroneous initiation.Curated

    Experimental Info

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti583 – 591DFCRDPLAH → AFLPRSAGD in AAA23522 (PubMed:2180922).Curated9
    Sequence conflicti596 – 598ASG → QR in AAA23522 (PubMed:2180922).Curated3
    Sequence conflicti747 – 777NGCAG…PPASS → MAVRVIRRWHGWKNTTVRN in AAA23522 (PubMed:2180922).CuratedAdd BLAST31

    Sequence databases

    Select the link destinations:

    EMBL nucleotide sequence database

    More...    EMBLi

    GenBank nucleotide sequence database

    More...    GenBanki

    DNA Data Bank of Japan; a nucleotide sequence database

    More...    DDBJi
    Links Updated
    		M34827 Genomic DNA Translation: AAA23522.1 Frameshift.
    U00039 Genomic DNA Translation: AAB18528.1 Different initiation.
    U00096 Genomic DNA Translation: AAC76575.3
    AP009048 Genomic DNA Translation: BAE77744.1 Different initiation.

    Protein sequence database of the Protein Information Resource

    More...    PIRi    		S47772

    NCBI Reference Sequences

    More...    RefSeqi    		NP_418007.3, NC_000913.3
    WP_000013950.1, NZ_LN832404.1

    Genome annotation databases

    Ensembl bacterial and archaeal genome annotation project

    More...    EnsemblBacteriai    		AAC76575; AAC76575; b3551
    BAE77744; BAE77744; BAE77744

    Database of genes from NCBI RefSeq genomes

    More...    GeneIDi    		946915

    KEGG: Kyoto Encyclopedia of Genes and Genomes

    More...    KEGGi    		ecj:JW5940
    eco:b3551

    Pathosystems Resource Integration Center (PATRIC)

    More...    PATRICi    		fig|1411691.4.peg.3163

    <p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

    <p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBLi
    GenBanki
    DDBJi
    Links Updated
    		M34827 Genomic DNA Translation: AAA23522.1 Frameshift.
    U00039 Genomic DNA Translation: AAB18528.1 Different initiation.
    U00096 Genomic DNA Translation: AAC76575.3
    AP009048 Genomic DNA Translation: BAE77744.1 Different initiation.
    PIRiS47772
    RefSeqiNP_418007.3, NC_000913.3
    WP_000013950.1, NZ_LN832404.1

    3D structure databases

    ProteinModelPortaliP20099
    SMRiP20099
    ModBaseiSearch...
    MobiDBiSearch...

    Protein-protein interaction databases

    BioGridi4261247, 8 interactors
    STRINGi316385.ECDH10B_3730

    Protein family/group databases

    TCDBi5.A.3.4.3 the prokaryotic molybdopterin-containing oxidoreductase (pmo) family

    Proteomic databases

    jPOSTiP20099
    PaxDbiP20099
    PRIDEiP20099

    Protocols and materials databases

    Structural Biology KnowledgebaseSearch...

    Genome annotation databases

    EnsemblBacteriaiAAC76575; AAC76575; b3551
    BAE77744; BAE77744; BAE77744
    GeneIDi946915
    KEGGiecj:JW5940
    eco:b3551
    PATRICifig|1411691.4.peg.3163

    Organism-specific databases

    EchoBASE - an integrated post-genomic database for E. coli

    More...    EchoBASEi    		EB0122
    EcoGeneiEG10124 bisC

    Phylogenomic databases

    eggNOGiENOG4107QY8 Bacteria
    COG0243 LUCA
    HOGENOMiHOG000284391
    InParanoidiP20099
    KOiK08351
    PhylomeDBiP20099

    Enzyme and pathway databases

    BioCyciEcoCyc:EG10124-MONOMER
    MetaCyc:EG10124-MONOMER
    SABIO-RKiP20099

    Miscellaneous databases

    Protein Ontology

    More...    PROi    		PR:P20099

    Family and domain databases

    InterProiView protein in InterPro
    IPR009010 Asp_de-COase-like_dom_sf
    IPR006658 BisC
    IPR006657 MoPterin_dinucl-bd_dom
    IPR006656 Mopterin_OxRdtase
    IPR006655 Mopterin_OxRdtase_prok_CS
    PfamiView protein in Pfam
    PF00384 Molybdopterin, 1 hit
    PF01568 Molydop_binding, 1 hit
    SUPFAMiSSF50692 SSF50692, 1 hit
    TIGRFAMsiTIGR00509 bisC_fam, 1 hit
    PROSITEiView protein in PROSITE
    PS00490 MOLYBDOPTERIN_PROK_2, 1 hit
    PS00932 MOLYBDOPTERIN_PROK_3, 1 hit

    ProtoNet; Automatic hierarchical classification of proteins

    More...    ProtoNeti    		Search...

    <p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

    <p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiBISC_ECOLI
    <p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P20099
    Secondary accession number(s): Q2M7L2
    <p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1991
    Last sequence update: May 30, 2000
    Last modified: January 16, 2019
    This is version 148 of the entry and version 3 of the sequence. See complete history.
    <p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    <p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Escherichia coli
      Escherichia coli (strain K12): entries and cross-references to EcoGene
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