AMY2B

Functionⁱ

Catalytic activityⁱ

Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1->4)-alpha-linked D-glucose units.By similarity

Cofactorⁱ

Protein has several cofactor binding sites:

Ca²⁺
By similarity
Manual assertion inferred from sequence similarity toⁱ
- UniProtKB:P04746 (AMYP_HUMAN)
Note: Binds 1 Ca²⁺ ion per subunit.
By similarity
Manual assertion inferred from sequence similarity toⁱ
- UniProtKB:P04746 (AMYP_HUMAN)
chloride
By similarity
Manual assertion inferred from sequence similarity toⁱ
- UniProtKB:P04746 (AMYP_HUMAN)
Note: Binds 1 Cl^- ion per subunit.
By similarity
Manual assertion inferred from sequence similarity toⁱ
- UniProtKB:P04746 (AMYP_HUMAN)

Sites

Feature key	Position(s)	DescriptionActions	Length
Metal bindingⁱ	115	CalciumBy similarity	1
Metal bindingⁱ	173	Calcium; via carbonyl oxygenBy similarity	1
Metal bindingⁱ	182	CalciumBy similarity	1
Binding siteⁱ	210	ChlorideBy similarity	1
Active siteⁱ	212	NucleophileBy similarity	1
Metal bindingⁱ	216	Calcium; via carbonyl oxygenBy similarity	1
Active siteⁱ	248	Proton donorBy similarity	1
Binding siteⁱ	313	ChlorideBy similarity	1
Siteⁱ	315	Transition state stabilizerBy similarity	1
Binding siteⁱ	352	ChlorideBy similarity	1

GO - Molecular functionⁱ

alpha-amylase activity
Source: UniProtKB
Inferred from sequence or structural similarityⁱ
- 2401405
alpha-amylase activity (releasing maltohexaose) Source: UniProtKB-EC
metal ion binding Source: UniProtKB-KW

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

carbohydrate metabolic process Source: UniProtKB-KW

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Glycosidase, Hydrolase
Biological process	Carbohydrate metabolism
Ligand	Calcium, Chloride, Metal-binding

Enzyme and pathway databases

Reactomeⁱ	R-HSA-189085 Digestion of dietary carbohydrate

Reactomeⁱ

R-HSA-189085 Digestion of dietary carbohydrate

Protein family/group databases

Carbohydrate-Active enZymes More...CAZyⁱ	GH13 Glycoside Hydrolase Family 13

CAZyⁱ

GH13 Glycoside Hydrolase Family 13

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Alpha-amylase 2B (EC:3.2.1.1By similarity) Alternative name(s): 1,4-alpha-D-glucan glucanohydrolase 2B Carcinoid alpha-amylase
Gene namesⁱ	Name:AMY2B
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 1

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000240038.6
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:478 AMY2B
MIMⁱ	104660 gene
neXtProtⁱ	NX_P19961

Keywords - Cellular componentⁱ

Secreted

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	280
Open Targets More...OpenTargetsⁱ	ENSG00000240038
PharmGKBⁱ	PA24785

Chemistry databases

Drug and drug target database More...DrugBankⁱ	DB02730 4-Methylthio-Alpha-D-Mannose DB03092 5-Hydroxymethyl-Chonduritol DB03277 alpha-maltotriose DB02379 Beta-D-Glucose DB03323 Maltose DB04417 P-Nitrophenol DB03088 Pyroglutamic Acid

DrugBankⁱ

DB02730 4-Methylthio-Alpha-D-Mannose
DB03092 5-Hydroxymethyl-Chonduritol
DB03277 alpha-maltotriose
DB02379 Beta-D-Glucose
DB03323 Maltose
DB04417 P-Nitrophenol
DB03088 Pyroglutamic Acid

Polymorphism and mutation databases

DMDMⁱ	113789

DMDMⁱ

113789

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Signal peptideⁱ	1 – 15	Add BLAST		15
ChainⁱPRO_0000001402	16 – 511	Alpha-amylase 2BAdd BLAST		496

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Modified residueⁱ	16	Pyrrolidone carboxylic acidBy similarity	1
Disulfide bondⁱ	43 ↔ 101	By similarity
Disulfide bondⁱ	85 ↔ 130	By similarity
Disulfide bondⁱ	156 ↔ 175	By similarity
Disulfide bondⁱ	393 ↔ 399	By similarity
Disulfide bondⁱ	465 ↔ 477	By similarity

Keywords - PTMⁱ

Disulfide bond, Pyrrolidone carboxylic acid

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	P19961
PaxDbⁱ	P19961
PeptideAtlas More...PeptideAtlasⁱ	P19961
PRIDEⁱ	P19961
ProteomicsDBⁱ	53704
TopDownProteomicsⁱ	P19961-1 [P19961-1]

PTM databases

iPTMnetⁱ	P19961
PhosphoSitePlusⁱ	P19961

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000240038 Expressed in 88 organ(s), highest expression level in body of pancreas
CleanExⁱ	HS_AMY2B
ExpressionAtlasⁱ	P19961 baseline and differential
Genevisibleⁱ	P19961 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA045394 HPA045399 HPA046980

HPAⁱ

HPA045394
HPA045399
HPA046980

Interactionⁱ

Subunit structureⁱ

Monomer.By similarity

Protein-protein interaction databases

BioGridⁱ	106777, 3 interactors
IntActⁱ	P19961, 2 interactors
STRINGⁱ	9606.ENSP00000354610

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P19961
SMRⁱ	P19961
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the glycosyl hydrolase 13 family.Curated

Keywords - Domainⁱ

Signal

Phylogenomic databases

eggNOGⁱ	KOG2212 Eukaryota COG0366 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000002882
HOGENOMⁱ	HOG000253313
HOVERGENⁱ	HBG000061
InParanoidⁱ	P19961
KEGG Orthology (KO) More...KOⁱ	K01176
OMAⁱ	WKCQHAW
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G07V6
PhylomeDBⁱ	P19961
TreeFamⁱ	TF312850

Family and domain databases

Gene3Dⁱ	2.60.40.1180, 1 hit
InterProⁱ	View protein in InterPro IPR006048 A-amylase/branching_C IPR031319 A-amylase_C IPR006046 Alpha_amylase IPR006047 Glyco_hydro_13_cat_dom IPR013780 Glyco_hydro_b IPR017853 Glycoside_hydrolase_SF
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00128 Alpha-amylase, 1 hit PF02806 Alpha-amylase_C, 1 hit
PRINTSⁱ	PR00110 ALPHAAMYLASE
SMARTⁱ	View protein in SMART SM00642 Aamy, 1 hit SM00632 Aamy_C, 1 hit
SUPFAMⁱ	SSF51445 SSF51445, 1 hit

Sequences (2+)ⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show all Align All

Isoform 1 (identifier: P19961-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MKFFLLLFTI GFCWAQYSPN TQQGRTSIVH LFEWRWVDIA LECERYLAPK 
        60         70         80         90        100
GFGGVQVSPP NENVAIHNPF RPWWERYQPV SYKLCTRSGN EDEFRNMVTR 
       110        120        130        140        150
CNNVGVRIYV DAVINHMSGN AVSAGTSSTC GSYFNPGSRD FPAVPYSGWD 
       160        170        180        190        200
FNDGKCKTGS GDIENYNDAT QVRDCRLVGL LDLALEKDYV RSKIAEYMNH 
       210        220        230        240        250
LIDIGVAGFR LDASKHMWPG DIKAILDKLH NLNSNWFPAG SKPFIYQEVI 
       260        270        280        290        300
DLGGEPIKSS DYFGNGRVTE FKYGAKLGTV IRKWNGEKMS YLKNWGEGWG 
       310        320        330        340        350
FMPSDRALVF VDNHDNQRGH GAGGASILTF WDARLYKMAV GFMLAHPYGF 
       360        370        380        390        400
TRVMSSYRWP RQFQNGNDVN DWVGPPNNNG VIKEVTINPD TTCGNDWVCE 
       410        420        430        440        450
HRWRQIRNMV NFRNVVDGQP FTNWYDNGSN QVAFGRGNRG FIVFNNDDWT 
       460        470        480        490        500
FSLTLQTGLP AGTYCDVISG DKINGNCTGI KIYVSDDGKA HFSISNSAED 
       510 
PFIAIHAESK L

Length:511

Mass (Da):57,710

Last modified:February 1, 1991 - v1

Checksum:ⁱ05FC3B1EC1143857

GO

Isoform 2 (identifier: P19961-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
368-370: DVN → EHG
371-511: Missing.

« Hide

        10         20         30         40         50
MKFFLLLFTI GFCWAQYSPN TQQGRTSIVH LFEWRWVDIA LECERYLAPK 
        60         70         80         90        100
GFGGVQVSPP NENVAIHNPF RPWWERYQPV SYKLCTRSGN EDEFRNMVTR 
       110        120        130        140        150
CNNVGVRIYV DAVINHMSGN AVSAGTSSTC GSYFNPGSRD FPAVPYSGWD 
       160        170        180        190        200
FNDGKCKTGS GDIENYNDAT QVRDCRLVGL LDLALEKDYV RSKIAEYMNH 
       210        220        230        240        250
LIDIGVAGFR LDASKHMWPG DIKAILDKLH NLNSNWFPAG SKPFIYQEVI 
       260        270        280        290        300
DLGGEPIKSS DYFGNGRVTE FKYGAKLGTV IRKWNGEKMS YLKNWGEGWG 
       310        320        330        340        350
FMPSDRALVF VDNHDNQRGH GAGGASILTF WDARLYKMAV GFMLAHPYGF 
       360        370
TRVMSSYRWP RQFQNGNEHG

Note: No experimental confirmation available.

Show »

Length:370

Mass (Da):42,021

Checksum:ⁱ2E294536A637C8CB

GO

Computationally mapped potential isoform sequencesⁱ

There are 2 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

C9J2Z5	C9J2Z5_HUMAN	Alpha-amylase 2B Alpha-amylase 2B	AMY2B	96	Annotation score:
C9JWK7	C9JWK7_HUMAN	Alpha-amylase 2B Alpha-amylase 2B	AMY2B	86	Annotation score:

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_056932	368 – 370	DVN → EHG in isoform 2. 1 Publication		3
Alternative sequenceⁱVSP_056933	371 – 511	Missing in isoform 2. 1 PublicationAdd BLAST		141

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	M24895 mRNA Translation: AAA35525.1 D90097 Genomic DNA Translation: BAA14130.1 AK095605 mRNA Translation: BAG53093.1 AK127047 mRNA Translation: BAG54429.1 AC105272 Genomic DNA No translation available. CH471097 Genomic DNA Translation: EAW72902.1 CH471097 Genomic DNA Translation: EAW72903.1 CH471097 Genomic DNA Translation: EAW72904.1 BC011179 mRNA Translation: AAH11179.1 BC020861 mRNA Translation: AAH20861.1 X07057 Genomic DNA Translation: CAA30100.1 M18670 Genomic DNA Translation: AAA51725.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS782.1 [P19961-1]
PIRⁱ	JS0165 ALHU2B
NCBI Reference Sequences More...RefSeqⁱ	NP_066188.1, NM_020978.4 [P19961-1]
UniGeneⁱ	Hs.484588

Genome annotation databases

Ensemblⁱ	ENST00000361355; ENSP00000354610; ENSG00000240038 [P19961-1] ENST00000477657; ENSP00000433347; ENSG00000240038 [P19961-2] ENST00000610648; ENSP00000481588; ENSG00000240038 [P19961-1]
GeneIDⁱ	280
KEGGⁱ	hsa:280
UCSC genome browser More...UCSCⁱ	uc001duq.5 human [P19961-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
P19961	Alpha-amylase (Fragment)		PANTR		91	UniRef100_P19961
Alpha-amylase 2B (Fragment)		HUMAN		86
UPI0008F5053E		GORGO		210
AMY2B isoform 4 (Fragment)		PANTR		86
Alpha-amylase 2B (Fragment)		HUMAN		96
+1

Protein	Similar proteins		Species	Score	Length	Source
P19961	Pancreatic alpha-amylase	)	HUMAN		511	UniRef90_P04746
Alpha-amylase		OTOGA		522
Alpha-amylase		CHLSB		513
Alpha-amylase (Fragment)		PANTR		91
Alpha-amylase		MACMU		511
+86
P19961-2	Alpha-amylase		PONAB		386	UniRef90_P19961-2
Alpha-amylase		PANTR		370
Alpha-amylase (Fragment)		PONAB		371

Protein	Similar proteins		Species	Score	Length	Source
P19961	Pancreatic alpha-amylase	)	HUMAN		511	UniRef50_P04746
Alpha-amylase 1		MOUSE		511
Alpha-amylase		OTOGA		522
Alpha-amylase		CHLSB		513
Alpha-amylase		TARSY		511
+254
P19961-2	Alpha-amylase		PONAB		386	UniRef50_P19961-2
Alpha-amylase		PANTR		370
Alpha-amylase (Fragment)		Ornithodoros turicata		407
Alpha-amylase		FUNHE		463
Alpha-amylase		STRMM		386
+6

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	M24895 mRNA Translation: AAA35525.1 D90097 Genomic DNA Translation: BAA14130.1 AK095605 mRNA Translation: BAG53093.1 AK127047 mRNA Translation: BAG54429.1 AC105272 Genomic DNA No translation available. CH471097 Genomic DNA Translation: EAW72902.1 CH471097 Genomic DNA Translation: EAW72903.1 CH471097 Genomic DNA Translation: EAW72904.1 BC011179 mRNA Translation: AAH11179.1 BC020861 mRNA Translation: AAH20861.1 X07057 Genomic DNA Translation: CAA30100.1 M18670 Genomic DNA Translation: AAA51725.1
CCDSⁱ	CCDS782.1 [P19961-1]
PIRⁱ	JS0165 ALHU2B
RefSeqⁱ	NP_066188.1, NM_020978.4 [P19961-1]
UniGeneⁱ	Hs.484588

3D structure databases

ProteinModelPortalⁱ	P19961
SMRⁱ	P19961
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	106777, 3 interactors
IntActⁱ	P19961, 2 interactors
STRINGⁱ	9606.ENSP00000354610

Chemistry databases

DrugBankⁱ	DB02730 4-Methylthio-Alpha-D-Mannose DB03092 5-Hydroxymethyl-Chonduritol DB03277 alpha-maltotriose DB02379 Beta-D-Glucose DB03323 Maltose DB04417 P-Nitrophenol DB03088 Pyroglutamic Acid

DrugBankⁱ

DB02730 4-Methylthio-Alpha-D-Mannose
DB03092 5-Hydroxymethyl-Chonduritol
DB03277 alpha-maltotriose
DB02379 Beta-D-Glucose
DB03323 Maltose
DB04417 P-Nitrophenol
DB03088 Pyroglutamic Acid

Protein family/group databases

CAZyⁱ	GH13 Glycoside Hydrolase Family 13

CAZyⁱ

GH13 Glycoside Hydrolase Family 13

PTM databases

iPTMnetⁱ	P19961
PhosphoSitePlusⁱ	P19961

Polymorphism and mutation databases

DMDMⁱ	113789

DMDMⁱ

113789

Proteomic databases

MaxQBⁱ	P19961
PaxDbⁱ	P19961
PeptideAtlasⁱ	P19961
PRIDEⁱ	P19961
ProteomicsDBⁱ	53704
TopDownProteomicsⁱ	P19961-1 [P19961-1]

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000361355; ENSP00000354610; ENSG00000240038 [P19961-1] ENST00000477657; ENSP00000433347; ENSG00000240038 [P19961-2] ENST00000610648; ENSP00000481588; ENSG00000240038 [P19961-1]
GeneIDⁱ	280
KEGGⁱ	hsa:280
UCSCⁱ	uc001duq.5 human [P19961-1]

Organism-specific databases

CTDⁱ	280
DisGeNETⁱ	280
EuPathDBⁱ	HostDB:ENSG00000240038.6
GeneCardsⁱ	AMY2B
HGNCⁱ	HGNC:478 AMY2B
HPAⁱ	HPA045394 HPA045399 HPA046980
MIMⁱ	104660 gene
neXtProtⁱ	NX_P19961
OpenTargetsⁱ	ENSG00000240038
PharmGKBⁱ	PA24785
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG2212 Eukaryota COG0366 LUCA
GeneTreeⁱ	ENSGT00390000002882
HOGENOMⁱ	HOG000253313
HOVERGENⁱ	HBG000061
InParanoidⁱ	P19961
KOⁱ	K01176
OMAⁱ	WKCQHAW
OrthoDBⁱ	EOG091G07V6
PhylomeDBⁱ	P19961
TreeFamⁱ	TF312850

Enzyme and pathway databases

Reactomeⁱ	R-HSA-189085 Digestion of dietary carbohydrate

Reactomeⁱ

R-HSA-189085 Digestion of dietary carbohydrate

Miscellaneous databases

ChiTaRSⁱ	AMY2B human
GeneWikiⁱ	AMY2B
GenomeRNAiⁱ	280
Protein Ontology More...PROⁱ	PR:P19961
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000240038 Expressed in 88 organ(s), highest expression level in body of pancreas
CleanExⁱ	HS_AMY2B
ExpressionAtlasⁱ	P19961 baseline and differential
Genevisibleⁱ	P19961 HS

Family and domain databases

Gene3Dⁱ	2.60.40.1180, 1 hit
InterProⁱ	View protein in InterPro IPR006048 A-amylase/branching_C IPR031319 A-amylase_C IPR006046 Alpha_amylase IPR006047 Glyco_hydro_13_cat_dom IPR013780 Glyco_hydro_b IPR017853 Glycoside_hydrolase_SF
Pfamⁱ	View protein in Pfam PF00128 Alpha-amylase, 1 hit PF02806 Alpha-amylase_C, 1 hit
PRINTSⁱ	PR00110 ALPHAAMYLASE
SMARTⁱ	View protein in SMART SM00642 Aamy, 1 hit SM00632 Aamy_C, 1 hit
SUPFAMⁱ	SSF51445 SSF51445, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	AMY2B_HUMAN
Accessionⁱ	P19961Primary (citable) accession number: P19961 Secondary accession number(s): B3KTI1 , B3KXB7, D3DT76, Q9UBH3
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	February 1, 1991
	Last sequence update:	February 1, 1991
	Last modified:	November 7, 2018
	This is version 180 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Direct protein sequencing, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Human chromosome 1
Human chromosome 1: entries, gene names and cross-references to MIM
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
Glycosyl hydrolases
Classification of glycosyl hydrolase families and list of entries

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UniProtKB - P19961 (AMY2B_HUMAN)

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Alpha-amylase 2B

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

Protein family/group databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted

Extracellular region or secreted

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Chemistry databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Chemistry databases

Protein family/group databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ