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UniProtKB - P19876 (CXCL3_HUMAN)

Entry version 179 (25 May 2022)
Sequence version 1 (01 Feb 1991)
Previous versions | rss
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Protein

C-X-C motif chemokine 3

Gene

CXCL3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Ligand for CXCR2 (By similarity).

Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes.

By similarity1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionCytokine
Biological processChemotaxis, Inflammatory response

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		P19876

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-380108, Chemokine receptors bind chemokines
R-HSA-418594, G alpha (i) signalling events

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		P19876

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
C-X-C motif chemokine 3
Alternative name(s):
GRO-gamma(1-73)
Growth-regulated protein gamma
Short name:
GRO-gamma
Macrophage inflammatory protein 2-beta
Short name:
MIP2-beta
Cleaved into the following chain:
GRO-gamma(5-73)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CXCL3
Synonyms:GRO3, GROG, SCYB3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:4604, CXCL3

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		139111, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_P19876

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000163734

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		2921

Open Targets

More...OpenTargetsi		ENSG00000163734

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA35052

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		P19876, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		CXCL3

Domain mapping of disease mutations (DMDM)

More...DMDMi		127086

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 341 PublicationAdd BLAST34
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000000506535 – 107C-X-C motif chemokine 3Add BLAST73
ChainiPRO_000000506639 – 107GRO-gamma(5-73)Add BLAST69

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi43 ↔ 69By similarity
Disulfide bondi45 ↔ 85By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

N-terminal processed form GRO-gamma(5-73) is produced by proteolytic cleavage after secretion from peripheral blood monocytes.1 Publication

Keywords - PTMi

Disulfide bond

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		P19876

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		P19876

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P19876

PeptideAtlas

More...PeptideAtlasi		P19876

PRoteomics IDEntifications database

More...PRIDEi		P19876

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		53698

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000163734, Expressed in smooth muscle tissue and 163 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		P19876, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000163734, Tissue enhanced (adipose tissue, cervix)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		109178, 12 interactors

Database of interacting proteins

More...DIPi		DIP-5909N

Protein interaction database and analysis system

More...IntActi		P19876, 4 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000296026

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		P19876, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

AlphaFold Protein Structure Database

More...AlphaFoldDBi		P19876

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P19876

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the intercrine alpha (chemokine CxC) family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502S7MM, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000163986

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_143902_1_1_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P19876

Identification of Orthologs from Complete Genome Data

More...OMAi		QPEVIAM

Database of Orthologous Groups

More...OrthoDBi		1618797at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		P19876

TreeFam database of animal gene trees

More...TreeFami		TF333433

Family and domain databases

Conserved Domains Database

More...CDDi		cd00273, Chemokine_CXC, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR001089, Chemokine_CXC
IPR018048, Chemokine_CXC_CS
IPR001811, Chemokine_IL8-like_dom
IPR033899, CXC_Chemokine_domain
IPR036048, Interleukin_8-like_sf

The PANTHER Classification System

More...PANTHERi		PTHR10179, PTHR10179, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00048, IL8, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00437, SMALLCYTKCXC

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00199, SCY, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF54117, SSF54117, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00471, SMALL_CYTOKINES_CXC, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

P19876-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAHATLSAAP SNPRLLRVAL LLLLLVAASR RAAGASVVTE LRCQCLQTLQ 
        60         70         80         90        100
GIHLKNIQSV NVRSPGPHCA QTEVIATLKN GKKACLNPAS PMVQKIIEKI 

LNKGSTN
Length:107
Mass (Da):11,342
Last modified:February 1, 1991 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i97A69946B7F1F070
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti27 – 28AA → G in AAA63184 (PubMed:2217207).Curated2

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_0592103H → R. Corresponds to variant dbSNP:rs352043Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
X53800 mRNA Translation: CAA37809.1
M36821 mRNA Translation: AAA63184.1
AC097709 Genomic DNA Translation: AAY41006.1
CH471057 Genomic DNA Translation: EAX05698.1
BC016308 mRNA Translation: AAH16308.1
BC065743 mRNA Translation: AAH65743.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS34007.1

Protein sequence database of the Protein Information Resource

More...PIRi		JH0282, B38290

NCBI Reference Sequences

More...RefSeqi		NP_002081.2, NM_002090.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000296026.4; ENSP00000296026.4; ENSG00000163734.4

Database of genes from NCBI RefSeq genomes

More...GeneIDi		2921

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:2921

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000296026.4; ENSP00000296026.4; NM_002090.3; NP_002081.2

UCSC genome browser

More...UCSCi		uc003hhl.5, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross%5Freferences%5Fsection">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Wikipedia

CXCL3 entry

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X53800 mRNA Translation: CAA37809.1
M36821 mRNA Translation: AAA63184.1
AC097709 Genomic DNA Translation: AAY41006.1
CH471057 Genomic DNA Translation: EAX05698.1
BC016308 mRNA Translation: AAH16308.1
BC065743 mRNA Translation: AAH65743.1
CCDSiCCDS34007.1
PIRiJH0282, B38290
RefSeqiNP_002081.2, NM_002090.2

3D structure databases

AlphaFoldDBiP19876
SMRiP19876
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi109178, 12 interactors
DIPiDIP-5909N
IntActiP19876, 4 interactors
STRINGi9606.ENSP00000296026

Genetic variation databases

BioMutaiCXCL3
DMDMi127086

Proteomic databases

EPDiP19876
MassIVEiP19876
PaxDbiP19876
PeptideAtlasiP19876
PRIDEiP19876
ProteomicsDBi53698

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		13341, 288 antibodies from 29 providers

The DNASU plasmid repository

More...DNASUi		2921

Genome annotation databases

EnsembliENST00000296026.4; ENSP00000296026.4; ENSG00000163734.4
GeneIDi2921
KEGGihsa:2921
MANE-SelectiENST00000296026.4; ENSP00000296026.4; NM_002090.3; NP_002081.2
UCSCiuc003hhl.5, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		2921
DisGeNETi2921

GeneCards: human genes, protein and diseases

More...GeneCardsi		CXCL3
HGNCiHGNC:4604, CXCL3
HPAiENSG00000163734, Tissue enhanced (adipose tissue, cervix)
MIMi139111, gene
neXtProtiNX_P19876
OpenTargetsiENSG00000163734
PharmGKBiPA35052
VEuPathDBiHostDB:ENSG00000163734

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG502S7MM, Eukaryota
GeneTreeiENSGT00940000163986
HOGENOMiCLU_143902_1_1_1
InParanoidiP19876
OMAiQPEVIAM
OrthoDBi1618797at2759
PhylomeDBiP19876
TreeFamiTF333433

Enzyme and pathway databases

PathwayCommonsiP19876
ReactomeiR-HSA-380108, Chemokine receptors bind chemokines
R-HSA-418594, G alpha (i) signalling events
SignaLinkiP19876

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		2921, 15 hits in 1008 CRISPR screens

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		CXCL3

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		2921
PharosiP19876, Tbio

Protein Ontology

More...PROi		PR:P19876
RNActiP19876, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000163734, Expressed in smooth muscle tissue and 163 other tissues
GenevisibleiP19876, HS

Family and domain databases

CDDicd00273, Chemokine_CXC, 1 hit
InterProiView protein in InterPro
IPR001089, Chemokine_CXC
IPR018048, Chemokine_CXC_CS
IPR001811, Chemokine_IL8-like_dom
IPR033899, CXC_Chemokine_domain
IPR036048, Interleukin_8-like_sf
PANTHERiPTHR10179, PTHR10179, 1 hit
PfamiView protein in Pfam
PF00048, IL8, 1 hit
PRINTSiPR00437, SMALLCYTKCXC
SMARTiView protein in SMART
SM00199, SCY, 1 hit
SUPFAMiSSF54117, SSF54117, 1 hit
PROSITEiView protein in PROSITE
PS00471, SMALL_CYTOKINES_CXC, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCXCL3_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P19876
Secondary accession number(s): Q4W5H9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1991
Last sequence update: February 1, 1991
Last modified: May 25, 2022
This is version 179 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families
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