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Entry version 181 (05 Jun 2019)
Sequence version 1 (01 Feb 1991)
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Protein

E3 ubiquitin-protein ligase UBR1

Gene

UBR1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine. EC:2.3.2.27

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri121 – 194UBR-typePROSITE-ProRule annotationAdd BLAST74
Zinc fingeri1220 – 1324RING-type; atypicalAdd BLAST105

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • proteasome regulatory particle binding Source: SGD
  • ubiquitin protein ligase activity Source: GO_Central
  • ubiquitin-protein transferase activity Source: SGD
  • zinc ion binding Source: InterPro

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTransferase
Biological processUbl conjugation pathway
LigandMetal-binding, Zinc

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
YEAST:G3O-30874-MONOMER

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
2.3.2.B9 984
6.3.2.19 984

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-SCE-983168 Antigen processing: Ubiquitination & Proteasome degradation

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00143

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
E3 ubiquitin-protein ligase UBR1 (EC:2.3.2.27)
Alternative name(s):
N-end-recognizing protein
N-recognin-1
RING-type E3 ubiquitin transferase UBR1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:UBR1
Synonyms:PTR1
Ordered Locus Names:YGR184C
ORF Names:G7168
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri559292 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002311 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome VII

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
FungiDB:YGR184C

Saccharomyces Genome Database

More...
SGDi
S000003416 UBR1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi1168K → S: Impairs interaction with UBC2, but does not affect degradation of N-end rule substrates. 1 Publication1
Mutagenesisi1169R → L: Impairs interaction with UBC2, but does not affect degradation of N-end rule substrates. 1 Publication1
Mutagenesisi1173K → A: Impairs interaction with UBC2, but does not affect degradation of N-end rule substrates. 1 Publication1
Mutagenesisi1220C → S: No effect on interaction with UBC2, but inhibits degradation of N-end rule substrates. 1 Publication1
Mutagenesisi1223C → S: No effect on interaction with UBC2, but inhibits degradation of N-end rule substrates. 1 Publication1
Mutagenesisi1295C → S: No effect on interaction with UBC2, but inhibits degradation of N-end rule substrates. 1 Publication1
Mutagenesisi1297H → A: No effect on interaction with UBC2, but inhibits degradation of N-end rule substrates. 1 Publication1
Mutagenesisi1320C → S: No effect on interaction with UBC2, but inhibits degradation of N-end rule substrates. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000561351 – 1950E3 ubiquitin-protein ligase UBR1Add BLAST1950

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei296PhosphoserineCombined sources1
Modified residuei300PhosphoserineCombined sources1
Modified residuei1938PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P19812

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P19812

PRoteomics IDEntifications database

More...
PRIDEi
P19812

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P19812

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with UBC2. Interacts with RPN2, RPT1 and RPT6 from the 26S proteasome.2 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
33436, 233 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-2918 UBR1-RAD6 ubiquitin ligase complex

Database of interacting proteins

More...
DIPi
DIP-2517N

Protein interaction database and analysis system

More...
IntActi
P19812, 18 interactors

Molecular INTeraction database

More...
MINTi
P19812

STRING: functional protein association networks

More...
STRINGi
4932.YGR184C

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

11950
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P19812

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
P19812

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1117 – 1219Interaction with UBC21 PublicationAdd BLAST103

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The RING-H2 zinc finger is an atypical RING finger with a His ligand in place of the fourth Cys of the classical motif.

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the UBR1 family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri121 – 194UBR-typePROSITE-ProRule annotationAdd BLAST74
Zinc fingeri1220 – 1324RING-type; atypicalAdd BLAST105

Keywords - Domaini

Zinc-finger

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183075

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000142344

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P19812

KEGG Orthology (KO)

More...
KOi
K10625

Identification of Orthologs from Complete Genome Data

More...
OMAi
WANTISM

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR039164 UBR1-like
IPR003126 Znf_UBR

The PANTHER Classification System

More...
PANTHERi
PTHR21497 PTHR21497, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02207 zf-UBR, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00396 ZnF_UBR1, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51157 ZF_UBR, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P19812-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSVADDDLGS LQGHIRRTLR SIHNLPYFRY TRGPTERADM SRALKEFIYR
60 70 80 90 100
YLYFVISNSG ENLPTLFNAH PKQKLSNPEL TVFPDSLEDA VDIDKITSQQ
110 120 130 140 150
TIPFYKIDES RIGDVHKHTG RNCGRKFKIG EPLYRCHECG CDDTCVLCIH
160 170 180 190 200
CFNPKDHVNH HVCTDICTEF TSGICDCGDE EAWNSPLHCK AEEQENDISE
210 220 230 240 250
DPATNADIKE EDVWNDSVNI ALVELVLAEV FDYFIDVFNQ NIEPLPTIQK
260 270 280 290 300
DITIKLREMT QQGKMYERAQ FLNDLKYEND YMFDGTTTAK TSPSNSPEAS
310 320 330 340 350
PSLAKIDPEN YTVIIYNDEY HNYSQATTAL RQGVPDNVHI DLLTSRIDGE
360 370 380 390 400
GRAMLKCSQD LSSVLGGFFA VQTNGLSATL TSWSEYLHQE TCKYIILWIT
410 420 430 440 450
HCLNIPNSSF QTTFRNMMGK TLCSEYLNAT ECRDMTPVVE KYFSNKFDKN
460 470 480 490 500
DPYRYIDLSI LADGNQIPLG HHKILPESST HSLSPLINDV ETPTSRTYSN
510 520 530 540 550
TRLQHILYFD NRYWKRLRKD IQNVIIPTLA SSNLYKPIFC QQVVEIFNHI
560 570 580 590 600
TRSVAYMDRE PQLTAIRECV VQLFTCPTNA KNIFENQSFL DIVWSIIDIF
610 620 630 640 650
KEFCKVEGGV LIWQRVQKSN LTKSYSISFK QGLYTVETLL SKVHDPNIPL
660 670 680 690 700
RPKEIISLLT LCKLFNGAWK IKRKEGEHVL HEDQNFISYL EYTTSIYSII
710 720 730 740 750
QTAEKVSEKS KDSIDSKLFL NAIRIISSFL GNRSLTYKLI YDSHEVIKFS
760 770 780 790 800
VSHERVAFMN PLQTMLSFLI EKVSLKDAYE ALEDCSDFLK ISDFSLRSVV
810 820 830 840 850
LCSQIDVGFW VRNGMSVLHQ ASYYKNNPEL GSYSRDIHLN QLAILWERDD
860 870 880 890 900
IPRIIYNILD RWELLDWFTG EVDYQHTVYE DKISFIIQQF IAFIYQILTE
910 920 930 940 950
RQYFKTFSSL KDRRMDQIKN SIIYNLYMKP LSYSKLLRSV PDYLTEDTTE
960 970 980 990 1000
FDEALEEVSV FVEPKGLADN GVFKLKASLY AKVDPLKLLN LENEFESSAT
1010 1020 1030 1040 1050
IIKSHLAKDK DEIAKVVLIP QVSIKQLDKD ALNLGAFTRN TVFAKVVYKL
1060 1070 1080 1090 1100
LQVCLDMEDS TFLNELLHLV HGIFRDDELI NGKDSIPEAY LSKPICNLLL
1110 1120 1130 1140 1150
SIANAKSDVF SESIVRKADY LLEKMIMKKP NELFESLIAS FGNQYVNDYK
1160 1170 1180 1190 1200
DKKLRQGVNL QETEKERKRR LAKKHQARLL AKFNNQQTKF MKEHESEFDE
1210 1220 1230 1240 1250
QDNDVDMVGE KVYESEDFTC ALCQDSSSTD FFVIPAYHDH SPIFRPGNIF
1260 1270 1280 1290 1300
NPNEFMPMWD GFYNDDEKQA YIDDDVLEAL KENGSCGSRK VFVSCNHHIH
1310 1320 1330 1340 1350
HNCFKRYVQK KRFSSNAFIC PLCQTFSNCT LPLCQTSKAN TGLSLDMFLE
1360 1370 1380 1390 1400
SELSLDTLSR LFKPFTEENY RTINSIFSLM ISQCQGFDKA VRKRANFSHK
1410 1420 1430 1440 1450
DVSLILSVHW ANTISMLEIA SRLEKPYSIS FFRSREQKYK TLKNILVCIM
1460 1470 1480 1490 1500
LFTFVIGKPS MEFEPYPQQP DTVWNQNQLF QYIVRSALFS PVSLRQTVTE
1510 1520 1530 1540 1550
ALTTFSRQFL RDFLQGLSDA EQVTKLYAKA SKIGDVLKVS EQMLFALRTI
1560 1570 1580 1590 1600
SDVRMEGLDS ESIIYDLAYT FLLKSLLPTI RRCLVFIKVL HELVKDSENE
1610 1620 1630 1640 1650
TLVINGHEVE EELEFEDTAE FVNKALKMIT EKESLVDLLT TQESIVSHPY
1660 1670 1680 1690 1700
LENIPYEYCG IIKLIDLSKY LNTYVTQSKE IKLREERSQH MKNADNRLDF
1710 1720 1730 1740 1750
KICLTCGVKV HLRADRHEMT KHLNKNCFKP FGAFLMPNSS EVCLHLTQPP
1760 1770 1780 1790 1800
SNIFISAPYL NSHGEVGRNA MRRGDLTTLN LKRYEHLNRL WINNEIPGYI
1810 1820 1830 1840 1850
SRVMGDEFRV TILSNGFLFA FNREPRPRRI PPTDEDDEDM EEGEDGFFTE
1860 1870 1880 1890 1900
GNDEMDVDDE TGQAANLFGV GAEGIAGGGV RDFFQFFENF RNTLQPQGNG
1910 1920 1930 1940 1950
DDDAPQNPPP ILQFLGPQFD GATIIRNTNP RNLDEDDSDD NDDSDEREIW
Length:1,950
Mass (Da):224,838
Last modified:February 1, 1991 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i33E4CD3A031AF523
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X53747 Genomic DNA Translation: CAA37779.1
X99074 Genomic DNA Translation: CAA67528.1
Z72969 Genomic DNA Translation: CAA97210.1
BK006941 Genomic DNA Translation: DAA08278.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S12332

NCBI Reference Sequences

More...
RefSeqi
NP_011700.1, NM_001181313.1

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
YGR184C_mRNA; YGR184C_mRNA; YGR184C

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
853096

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
sce:YGR184C

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X53747 Genomic DNA Translation: CAA37779.1
X99074 Genomic DNA Translation: CAA67528.1
Z72969 Genomic DNA Translation: CAA97210.1
BK006941 Genomic DNA Translation: DAA08278.1
PIRiS12332
RefSeqiNP_011700.1, NM_001181313.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3NIHX-ray2.10A115-194[»]
3NIIX-ray2.10A115-194[»]
3NIJX-ray2.10A115-194[»]
3NIKX-ray1.85A/B/D/F115-194[»]
3NILX-ray1.75A/B/D/F115-194[»]
3NIMX-ray2.00A/B/D/F115-194[»]
3NINX-ray2.10A/B115-194[»]
3NISX-ray1.68A/B/D/F115-194[»]
3NITX-ray2.60A107-194[»]
SMRiP19812
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi33436, 233 interactors
ComplexPortaliCPX-2918 UBR1-RAD6 ubiquitin ligase complex
DIPiDIP-2517N
IntActiP19812, 18 interactors
MINTiP19812
STRINGi4932.YGR184C

PTM databases

iPTMnetiP19812

Proteomic databases

MaxQBiP19812
PaxDbiP19812
PRIDEiP19812

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYGR184C_mRNA; YGR184C_mRNA; YGR184C
GeneIDi853096
KEGGisce:YGR184C

Organism-specific databases

EuPathDBiFungiDB:YGR184C
SGDiS000003416 UBR1

Phylogenomic databases

GeneTreeiENSGT00950000183075
HOGENOMiHOG000142344
InParanoidiP19812
KOiK10625
OMAiWANTISM

Enzyme and pathway databases

UniPathwayiUPA00143
BioCyciYEAST:G3O-30874-MONOMER
BRENDAi2.3.2.B9 984
6.3.2.19 984
ReactomeiR-SCE-983168 Antigen processing: Ubiquitination & Proteasome degradation

Miscellaneous databases

EvolutionaryTraceiP19812

Protein Ontology

More...
PROi
PR:P19812

Family and domain databases

InterProiView protein in InterPro
IPR039164 UBR1-like
IPR003126 Znf_UBR
PANTHERiPTHR21497 PTHR21497, 1 hit
PfamiView protein in Pfam
PF02207 zf-UBR, 1 hit
SMARTiView protein in SMART
SM00396 ZnF_UBR1, 1 hit
PROSITEiView protein in PROSITE
PS51157 ZF_UBR, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiUBR1_YEAST
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P19812
Secondary accession number(s): D6VUW7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1991
Last sequence update: February 1, 1991
Last modified: June 5, 2019
This is version 181 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome VII
    Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. SIMILARITY comments
    Index of protein domains and families
  5. PATHWAY comments
    Index of metabolic and biosynthesis pathways
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