UniProtKB - P19801 (AOC1_HUMAN)
Protein
Amiloride-sensitive amine oxidase [copper-containing]
Gene
AOC1
Organism
Homo sapiens (Human)
Status
Functioni
Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function.
Miscellaneous
Inhibited by amiloride in a competitive manner.By similarity
Catalytic activityi
- EC:1.4.3.221 Publication
Cofactori
Protein has several cofactor binding sites:- Cu cation1 PublicationNote: Binds 1 copper ion per subunit.1 Publication
- Ca2+1 PublicationNote: Binds 2 calcium ions per subunit.1 Publication
- L-topaquinone1 PublicationNote: Contains 1 topaquinone per subunit.1 Publication
Activity regulationi
Inhibited by isoniazid, cimetidine, clonidine, pentamidine, berenil and pentamidine.1 Publication
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 373 | Proton acceptor1 Publication | 1 | |
Active sitei | 461 | Schiff-base intermediate with substrate; via topaquinoneCombined sources1 Publication | 1 | |
Metal bindingi | 510 | Copper; via tele nitrogenCombined sources1 Publication | 1 | |
Metal bindingi | 512 | Copper; via tele nitrogenCombined sources1 Publication | 1 | |
Metal bindingi | 519 | Calcium 1Combined sources1 Publication | 1 | |
Metal bindingi | 520 | Calcium 1; via carbonyl oxygenCombined sources1 Publication | 1 | |
Metal bindingi | 521 | Calcium 1Combined sources1 Publication | 1 | |
Metal bindingi | 562 | Calcium 2Combined sources1 Publication | 1 | |
Metal bindingi | 653 | Calcium 2; via carbonyl oxygenCombined sources1 Publication | 1 | |
Metal bindingi | 656 | Calcium 2Combined sources1 Publication | 1 | |
Metal bindingi | 658 | Calcium 2Combined sources1 Publication | 1 | |
Metal bindingi | 664 | Calcium 1Combined sources1 Publication | 1 | |
Metal bindingi | 665 | Calcium 1; via carbonyl oxygenCombined sources1 Publication | 1 | |
Metal bindingi | 675 | Copper; via pros nitrogenCombined sources1 Publication | 1 |
GO - Molecular functioni
- calcium ion binding Source: UniProtKB
- copper ion binding Source: UniProtKB
- diamine oxidase activity Source: UniProtKB
- heparin binding Source: UniProtKB
- histamine oxidase activity Source: UniProtKB-EC
- methylputrescine oxidase activity Source: UniProtKB-EC
- primary amine oxidase activity Source: UniProtKB
- propane-1,3-diamine oxidase activity Source: UniProtKB-EC
- protein-containing complex binding Source: UniProtKB
- protein homodimerization activity Source: UniProtKB
- quinone binding Source: UniProtKB
- zinc ion binding Source: UniProtKB
GO - Biological processi
- amine metabolic process Source: GO_Central
- cellular response to azide Source: UniProtKB
- cellular response to copper ion Source: UniProtKB
- cellular response to copper ion starvation Source: UniProtKB
- cellular response to heparin Source: UniProtKB
- cellular response to histamine Source: UniProtKB
- neutrophil degranulation Source: Reactome
- oxidation-reduction process Source: UniProtKB
- putrescine metabolic process Source: UniProtKB
- response to antibiotic Source: UniProtKB
- xenobiotic metabolic process Source: Reactome
Keywordsi
Molecular function | Heparin-binding, Oxidoreductase |
Ligand | Calcium, Copper, Metal-binding |
Enzyme and pathway databases
BioCyci | MetaCyc:HS00083-MONOMER |
BRENDAi | 1.4.3.22, 2681 |
PathwayCommonsi | P19801 |
Reactomei | R-HSA-211945, Phase I - Functionalization of compounds R-HSA-6798695, Neutrophil degranulation |
Names & Taxonomyi
Protein namesi | Recommended name: Amiloride-sensitive amine oxidase [copper-containing] (EC:1.4.3.221 Publication)Short name: DAO Short name: Diamine oxidase Alternative name(s): Amiloride-binding protein 1 Amine oxidase copper domain-containing protein 1 Histaminase Kidney amine oxidase Short name: KAO |
Gene namesi | Name:AOC1 Synonyms:ABP1, DAO1 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000002726.19 |
HGNCi | HGNC:80, AOC1 |
MIMi | 104610, gene |
neXtProti | NX_P19801 |
Subcellular locationi
Extracellular region or secreted
Extracellular region or secreted
- extracellular exosome Source: UniProtKB
- extracellular region Source: Reactome
- extracellular space Source: UniProtKB
Peroxisome
- peroxisome Source: UniProtKB
Plasma Membrane
- plasma membrane Source: UniProtKB
Other locations
- bicellular tight junction Source: UniProtKB
- specific granule lumen Source: Reactome
Keywords - Cellular componenti
SecretedPathology & Biotechi
Organism-specific databases
DisGeNETi | 26 |
OpenTargetsi | ENSG00000002726 |
PharmGKBi | PA24416 |
Miscellaneous databases
Pharosi | P19801, Tchem |
Chemistry databases
ChEMBLi | CHEMBL2118 |
DrugBanki | DB00594, Amiloride DB01373, Calcium DB09130, Copper DB03608, Diminazene |
DrugCentrali | P19801 |
Polymorphism and mutation databases
BioMutai | AOC1 |
DMDMi | 251757489 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 19 | 1 PublicationAdd BLAST | 19 | |
ChainiPRO_0000035666 | 20 – 751 | Amiloride-sensitive amine oxidase [copper-containing]Add BLAST | 732 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 110 | N-linked (GlcNAc...) asparagineCombined sources1 Publication | 1 | |
Glycosylationi | 168 | N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation | 1 | |
Disulfide bondi | 177 ↔ 181 | Combined sources1 Publication | ||
Disulfide bondi | 391 ↔ 417 | Combined sources1 Publication | ||
Modified residuei | 461 | 2',4',5'-topaquinone1 Publication | 1 | |
Glycosylationi | 538 | N-linked (GlcNAc...) asparagineCombined sources1 Publication | 1 | |
Disulfide bondi | 736 | InterchainCombined sources1 Publication | ||
Glycosylationi | 745 | N-linked (GlcNAc...) asparagineCombined sources1 Publication | 1 |
Post-translational modificationi
Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.By similarity
Keywords - PTMi
Disulfide bond, Glycoprotein, TPQProteomic databases
CPTACi | CPTAC-2204 |
jPOSTi | P19801 |
MassIVEi | P19801 |
PaxDbi | P19801 |
PeptideAtlasi | P19801 |
PRIDEi | P19801 |
ProteomicsDBi | 53688 [P19801-1] 53689 [P19801-2] 8732 |
TopDownProteomicsi | P19801-1 [P19801-1] |
PTM databases
GlyGeni | P19801, 5 sites, 2 O-linked glycans (1 site) |
iPTMneti | P19801 |
PhosphoSitePlusi | P19801 |
Expressioni
Tissue specificityi
Placenta and kidney.
Gene expression databases
Bgeei | ENSG00000002726, Expressed in placenta and 113 other tissues |
ExpressionAtlasi | P19801, baseline and differential |
Genevisiblei | P19801, HS |
Organism-specific databases
HPAi | ENSG00000002726, Group enriched (intestine, placenta) |
Interactioni
Subunit structurei
Homodimer; disulfide-linked.
1 PublicationBinary interactionsi
Hide detailsP19801
GO - Molecular functioni
- protein homodimerization activity Source: UniProtKB
Protein-protein interaction databases
BioGRIDi | 106544, 14 interactors |
IntActi | P19801, 10 interactors |
STRINGi | 9606.ENSP00000411613 |
Chemistry databases
BindingDBi | P19801 |
Miscellaneous databases
RNActi | P19801, protein |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | P19801 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P19801 |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 371 – 381 | Substrate bindingCombined sources1 PublicationAdd BLAST | 11 | |
Regioni | 458 – 463 | Substrate bindingCombined sources1 Publication | 6 | |
Regioni | 568 – 575 | Heparin-bindingBy similarity | 8 |
Sequence similaritiesi
Belongs to the copper/topaquinone oxidase family.Curated
Keywords - Domaini
SignalPhylogenomic databases
eggNOGi | KOG1186, Eukaryota |
GeneTreei | ENSGT00950000183207 |
HOGENOMi | CLU_015739_1_0_1 |
InParanoidi | P19801 |
OMAi | GKKFPRY |
OrthoDBi | 1320015at2759 |
PhylomeDBi | P19801 |
TreeFami | TF314750 |
Family and domain databases
Gene3Di | 2.70.98.20, 1 hit |
InterProi | View protein in InterPro IPR000269, Cu_amine_oxidase IPR015798, Cu_amine_oxidase_C IPR036460, Cu_amine_oxidase_C_sf IPR016182, Cu_amine_oxidase_N-reg IPR015800, Cu_amine_oxidase_N2 IPR015802, Cu_amine_oxidase_N3 |
PANTHERi | PTHR10638, PTHR10638, 1 hit |
Pfami | View protein in Pfam PF01179, Cu_amine_oxid, 1 hit PF02727, Cu_amine_oxidN2, 1 hit PF02728, Cu_amine_oxidN3, 1 hit |
PRINTSi | PR00766, CUDAOXIDASE |
SUPFAMi | SSF49998, SSF49998, 1 hit SSF54416, SSF54416, 2 hits |
PROSITEi | View protein in PROSITE PS01164, COPPER_AMINE_OXID_1, 1 hit PS01165, COPPER_AMINE_OXID_2, 1 hit |
s (2+)i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All
Isoform 1 (identifier: P19801-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MPALGWAVAA ILMLQTAMAE PSPGTLPRKA GVFSDLSNQE LKAVHSFLWS
60 70 80 90 100
KKELRLQPSS TTTMAKNTVF LIEMLLPKKY HVLRFLDKGE RHPVREARAV
110 120 130 140 150
IFFGDQEHPN VTEFAVGPLP GPCYMRALSP RPGYQSSWAS RPISTAEYAL
160 170 180 190 200
LYHTLQEATK PLHQFFLNTT GFSFQDCHDR CLAFTDVAPR GVASGQRRSW
210 220 230 240 250
LIIQRYVEGY FLHPTGLELL VDHGSTDAGH WAVEQVWYNG KFYGSPEELA
260 270 280 290 300
RKYADGEVDV VVLEDPLPGG KGHDSTEEPP LFSSHKPRGD FPSPIHVSGP
310 320 330 340 350
RLVQPHGPRF RLEGNAVLYG GWSFAFRLRS SSGLQVLNVH FGGERIAYEV
360 370 380 390 400
SVQEAVALYG GHTPAGMQTK YLDVGWGLGS VTHELAPGID CPETATFLDT
410 420 430 440 450
FHYYDADDPV HYPRALCLFE MPTGVPLRRH FNSNFKGGFN FYAGLKGQVL
460 470 480 490 500
VLRTTSTVYN YDYIWDFIFY PNGVMEAKMH ATGYVHATFY TPEGLRHGTR
510 520 530 540 550
LHTHLIGNIH THLVHYRVDL DVAGTKNSFQ TLQMKLENIT NPWSPRHRVV
560 570 580 590 600
QPTLEQTQYS WERQAAFRFK RKLPKYLLFT SPQENPWGHK RTYRLQIHSM
610 620 630 640 650
ADQVLPPGWQ EEQAITWARY PLAVTKYRES ELCSSSIYHQ NDPWHPPVVF
660 670 680 690 700
EQFLHNNENI ENEDLVAWVT VGFLHIPHSE DIPNTATPGN SVGFLLRPFN
710 720 730 740 750
FFPEDPSLAS RDTVIVWPRD NGPNYVQRWI PEDRDCSMPP PFSYNGTYRP
V
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketC9J2J4 | C9J2J4_HUMAN | Amine oxidase | AOC1 | 337 | Annotation score: | ||
C9J0G8 | C9J0G8_HUMAN | Amine oxidase | AOC1 | 249 | Annotation score: |
Sequence cautioni
The sequence AAA58358 differs from that shown. Reason: Frameshift.Curated
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length | |
---|---|---|---|---|---|
Sequence conflicti | 28 | R → A AA sequence (PubMed:8144586).Curated | 1 | ||
Sequence conflicti | 280 | P → A in AAA58358 (PubMed:2217167).Curated | 1 | ||
Sequence conflicti | 290 | D → T in AAA58358 (PubMed:2217167).Curated | 1 | ||
Sequence conflicti | 572 | K → R in AAA58358 (PubMed:2217167).Curated | 1 | ||
Sequence conflicti | 592 | T → S in AAA58358 (PubMed:2217167).Curated | 1 | ||
Sequence conflicti | 592 | T → S in CAA55046 (PubMed:8182053).Curated | 1 | ||
Sequence conflicti | 592 | T → S in AAC50270 (PubMed:8595053).Curated | 1 | ||
Sequence conflicti | 592 | T → S in AAB60381 (PubMed:8595053).Curated | 1 | ||
Sequence conflicti | 592 | T → S in AAH14093 (PubMed:15489334).Curated | 1 | ||
Isoform 2 (identifier: P19801-2) | |||||
Sequence conflicti | 632 | A → R in AAB60381 (PubMed:8595053).Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_025078 | 16 | T → M1 PublicationCorresponds to variant dbSNP:rs10156191Ensembl. | 1 | |
Natural variantiVAR_025079 | 332 | S → F2 PublicationsCorresponds to variant dbSNP:rs1049742Ensembl. | 1 | |
Natural variantiVAR_025080 | 479 | M → I1 PublicationCorresponds to variant dbSNP:rs45558339Ensembl. | 1 | |
Natural variantiVAR_007542 | 645 | H → D4 PublicationsCorresponds to variant dbSNP:rs1049793Ensembl. | 1 | |
Natural variantiVAR_025081 | 659 | N → H1 PublicationCorresponds to variant dbSNP:rs35070995EnsemblClinVar. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_055190 | 618 | A → ARTEGGQPRALSQAASPVPG in isoform 2. 1 Publication | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M55602 mRNA Translation: AAA58358.1 Frameshift. X78212 Genomic DNA Translation: CAA55046.1 U11862 mRNA Translation: AAC50270.1 U11863 mRNA Translation: AAB60381.1 AY948960 Genomic DNA Translation: AAX81409.1 AC006343 Genomic DNA No translation available. AC006479 Genomic DNA No translation available. BC014093 mRNA Translation: AAH14093.1 |
CCDSi | CCDS43679.1 [P19801-1] CCDS64797.1 [P19801-2] |
PIRi | A54053 |
RefSeqi | NP_001082.2, NM_001091.3 [P19801-1] NP_001259001.1, NM_001272072.1 [P19801-2] XP_016867433.1, XM_017011944.1 [P19801-2] XP_016867434.1, XM_017011945.1 [P19801-2] XP_016867435.1, XM_017011946.1 [P19801-2] XP_016867436.1, XM_017011947.1 [P19801-1] |
Genome annotation databases
Ensembli | ENST00000360937; ENSP00000354193; ENSG00000002726 [P19801-1] ENST00000416793; ENSP00000411613; ENSG00000002726 [P19801-2] ENST00000467291; ENSP00000418328; ENSG00000002726 [P19801-1] ENST00000493429; ENSP00000418614; ENSG00000002726 [P19801-1] |
GeneIDi | 26 |
KEGGi | hsa:26 |
UCSCi | uc003whz.3, human [P19801-1] |
Keywords - Coding sequence diversityi
Alternative splicing, PolymorphismSimilar proteinsi
Cross-referencesi
Web resourcesi
NIEHS-SNPs |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M55602 mRNA Translation: AAA58358.1 Frameshift. X78212 Genomic DNA Translation: CAA55046.1 U11862 mRNA Translation: AAC50270.1 U11863 mRNA Translation: AAB60381.1 AY948960 Genomic DNA Translation: AAX81409.1 AC006343 Genomic DNA No translation available. AC006479 Genomic DNA No translation available. BC014093 mRNA Translation: AAH14093.1 |
CCDSi | CCDS43679.1 [P19801-1] CCDS64797.1 [P19801-2] |
PIRi | A54053 |
RefSeqi | NP_001082.2, NM_001091.3 [P19801-1] NP_001259001.1, NM_001272072.1 [P19801-2] XP_016867433.1, XM_017011944.1 [P19801-2] XP_016867434.1, XM_017011945.1 [P19801-2] XP_016867435.1, XM_017011946.1 [P19801-2] XP_016867436.1, XM_017011947.1 [P19801-1] |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
3HI7 | X-ray | 1.80 | A/B | 21-751 | [»] | |
3HIG | X-ray | 2.09 | A/B | 21-751 | [»] | |
3HII | X-ray | 2.15 | A/B | 21-751 | [»] | |
3K5T | X-ray | 2.11 | A | 21-751 | [»] | |
3MPH | X-ray | 2.05 | A/B | 21-751 | [»] | |
SMRi | P19801 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 106544, 14 interactors |
IntActi | P19801, 10 interactors |
STRINGi | 9606.ENSP00000411613 |
Chemistry databases
BindingDBi | P19801 |
ChEMBLi | CHEMBL2118 |
DrugBanki | DB00594, Amiloride DB01373, Calcium DB09130, Copper DB03608, Diminazene |
DrugCentrali | P19801 |
PTM databases
GlyGeni | P19801, 5 sites, 2 O-linked glycans (1 site) |
iPTMneti | P19801 |
PhosphoSitePlusi | P19801 |
Polymorphism and mutation databases
BioMutai | AOC1 |
DMDMi | 251757489 |
Proteomic databases
CPTACi | CPTAC-2204 |
jPOSTi | P19801 |
MassIVEi | P19801 |
PaxDbi | P19801 |
PeptideAtlasi | P19801 |
PRIDEi | P19801 |
ProteomicsDBi | 53688 [P19801-1] 53689 [P19801-2] 8732 |
TopDownProteomicsi | P19801-1 [P19801-1] |
Protocols and materials databases
Antibodypediai | 10528, 371 antibodies |
DNASUi | 26 |
Genome annotation databases
Ensembli | ENST00000360937; ENSP00000354193; ENSG00000002726 [P19801-1] ENST00000416793; ENSP00000411613; ENSG00000002726 [P19801-2] ENST00000467291; ENSP00000418328; ENSG00000002726 [P19801-1] ENST00000493429; ENSP00000418614; ENSG00000002726 [P19801-1] |
GeneIDi | 26 |
KEGGi | hsa:26 |
UCSCi | uc003whz.3, human [P19801-1] |
Organism-specific databases
CTDi | 26 |
DisGeNETi | 26 |
EuPathDBi | HostDB:ENSG00000002726.19 |
GeneCardsi | AOC1 |
HGNCi | HGNC:80, AOC1 |
HPAi | ENSG00000002726, Group enriched (intestine, placenta) |
MIMi | 104610, gene |
neXtProti | NX_P19801 |
OpenTargetsi | ENSG00000002726 |
PharmGKBi | PA24416 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG1186, Eukaryota |
GeneTreei | ENSGT00950000183207 |
HOGENOMi | CLU_015739_1_0_1 |
InParanoidi | P19801 |
OMAi | GKKFPRY |
OrthoDBi | 1320015at2759 |
PhylomeDBi | P19801 |
TreeFami | TF314750 |
Enzyme and pathway databases
BioCyci | MetaCyc:HS00083-MONOMER |
BRENDAi | 1.4.3.22, 2681 |
PathwayCommonsi | P19801 |
Reactomei | R-HSA-211945, Phase I - Functionalization of compounds R-HSA-6798695, Neutrophil degranulation |
Miscellaneous databases
BioGRID-ORCSi | 26, 3 hits in 819 CRISPR screens |
ChiTaRSi | AOC1, human |
EvolutionaryTracei | P19801 |
GenomeRNAii | 26 |
Pharosi | P19801, Tchem |
PROi | PR:P19801 |
RNActi | P19801, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000002726, Expressed in placenta and 113 other tissues |
ExpressionAtlasi | P19801, baseline and differential |
Genevisiblei | P19801, HS |
Family and domain databases
Gene3Di | 2.70.98.20, 1 hit |
InterProi | View protein in InterPro IPR000269, Cu_amine_oxidase IPR015798, Cu_amine_oxidase_C IPR036460, Cu_amine_oxidase_C_sf IPR016182, Cu_amine_oxidase_N-reg IPR015800, Cu_amine_oxidase_N2 IPR015802, Cu_amine_oxidase_N3 |
PANTHERi | PTHR10638, PTHR10638, 1 hit |
Pfami | View protein in Pfam PF01179, Cu_amine_oxid, 1 hit PF02727, Cu_amine_oxidN2, 1 hit PF02728, Cu_amine_oxidN3, 1 hit |
PRINTSi | PR00766, CUDAOXIDASE |
SUPFAMi | SSF49998, SSF49998, 1 hit SSF54416, SSF54416, 2 hits |
PROSITEi | View protein in PROSITE PS01164, COPPER_AMINE_OXID_1, 1 hit PS01165, COPPER_AMINE_OXID_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | AOC1_HUMAN | |
Accessioni | P19801Primary (citable) accession number: P19801 Secondary accession number(s): C9J690 Q6GU42 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 1, 1991 |
Last sequence update: | July 7, 2009 | |
Last modified: | December 2, 2020 | |
This is version 204 of the entry and version 4 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencing, Reference proteomeDocuments
- Human chromosome 7
Human chromosome 7: entries, gene names and cross-references to MIM - Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families - Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations