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Protein

Curculin-1

Gene

CUR09

Organism
Molineria latifolia (Lumbah) (Curculigo latifolia)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Taste-modifying protein; sweet-tasting. After curculin, water elicits a sweet taste, and sour substances induce a stronger sense of sweetness.

GO - Molecular functioni

Keywordsi

Molecular functionTaste-modifying protein
LigandLectin

Names & Taxonomyi

Protein namesi
Recommended name:
Curculin-1
Alternative name(s):
Neoculin basic subunit
Short name:
NBS
Gene namesi
Name:CUR09
Synonyms:CUR37
OrganismiMolineria latifolia (Lumbah) (Curculigo latifolia)
Taxonomic identifieri4676 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaAsparagalesHypoxidaceaeMolineria

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 221 PublicationAdd BLAST22
ChainiPRO_000002104223 – 136Curculin-1Add BLAST114
PropeptideiPRO_0000021043137 – 158Add BLAST22

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi51 ↔ 74
Disulfide bondi99Interchain (with C-131)
Disulfide bondi131Interchain (with C-99)

Keywords - PTMi

Disulfide bond

Interactioni

Subunit structurei

Homodimer and heterodimer with curculin-2; Disulfide-linked.2 Publications

Structurei

Secondary structure

1158
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliP19667
SMRiP19667
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP19667

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini23 – 131Bulb-type lectinPROSITE-ProRule annotationAdd BLAST109

Keywords - Domaini

Signal

Family and domain databases

CDDicd00028 B_lectin, 1 hit
Gene3Di2.90.10.10, 1 hit
InterProiView protein in InterPro
IPR001480 Bulb-type_lectin_dom
IPR036426 Bulb-type_lectin_dom_sf
PfamiView protein in Pfam
PF01453 B_lectin, 1 hit
SMARTiView protein in SMART
SM00108 B_lectin, 1 hit
SUPFAMiSSF51110 SSF51110, 1 hit
PROSITEiView protein in PROSITE
PS50927 BULB_LECTIN, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P19667-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAKFLLTIL VTFAAVASLG MADNVLLSGQ TLHADHSLQA GAYTLTIQNK
60 70 80 90 100
CNLVKYQNGR QIWASNTDRR GSGCRLTLLS DGNLVIYDHN NNDVWGSACW
110 120 130 140 150
GDNGKYALVL QKDGRFVIYG PVLWSLGPNG CRRVNGGITV AKDSTEPQHE

DIKMVINN
Length:158
Mass (Da):17,223
Last modified:July 15, 1998 - v2
Checksum:i65B51E742D34706E
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti50K → N AA sequence (PubMed:2394746).Curated1
Sequence conflicti95W → N AA sequence (PubMed:2394746).Curated1
Sequence conflicti100W → C AA sequence (PubMed:2394746).Curated1
Sequence conflicti103N → A AA sequence (PubMed:2394746).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X64110 mRNA Translation: CAA45476.1
X64111 mRNA Translation: CAA45477.1
PIRiS22365

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X64110 mRNA Translation: CAA45476.1
X64111 mRNA Translation: CAA45477.1
PIRiS22365

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2D04X-ray2.76B/D/F/H23-136[»]
2DPFX-ray1.50A/B/C/D23-136[»]
ProteinModelPortaliP19667
SMRiP19667
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiP19667

Family and domain databases

CDDicd00028 B_lectin, 1 hit
Gene3Di2.90.10.10, 1 hit
InterProiView protein in InterPro
IPR001480 Bulb-type_lectin_dom
IPR036426 Bulb-type_lectin_dom_sf
PfamiView protein in Pfam
PF01453 B_lectin, 1 hit
SMARTiView protein in SMART
SM00108 B_lectin, 1 hit
SUPFAMiSSF51110 SSF51110, 1 hit
PROSITEiView protein in PROSITE
PS50927 BULB_LECTIN, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiCURC1_MOLLA
AccessioniPrimary (citable) accession number: P19667
Secondary accession number(s): Q39530, Q39531
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1991
Last sequence update: July 15, 1998
Last modified: September 12, 2018
This is version 77 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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