Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 174 (18 Sep 2019)
Sequence version 1 (01 Feb 1991)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Galactoside 2-alpha-L-fucosyltransferase 1

Gene

FUT1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Gal-beta-) called the H antigen which is an essential substrate for the final step in the soluble A and B antigen synthesis pathway.1 Publication

Miscellaneous

There are two genes (FUT1 and FUT2) which encode galactoside 2-L-fucosyltransferase. They are expressed in a tissue-specific manner with expression restricted to cells of mesodermal or endodermal origin respectively.

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the ‘Function’ section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

  1. KM=2.4 mM for phenyl beta-D-galactoside1 Publication

    <p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: protein glycosylation

    This protein is involved in the pathway protein glycosylation, which is part of Protein modification.
    View all proteins of this organism that are known to be involved in the pathway protein glycosylation and in Protein modification.

    <p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

    GO - Biological processi

    <p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

    Molecular functionBlood group antigen, Glycosyltransferase, Transferase

    Enzyme and pathway databases

    BioCyc Collection of Pathway/Genome Databases

    More...
    BioCyci
    MetaCyc:HS10855-MONOMER

    BRENDA Comprehensive Enzyme Information System

    More...
    BRENDAi
    2.4.1.69 2681

    Reactome - a knowledgebase of biological pathways and processes

    More...
    Reactomei
    R-HSA-9033807 ABO blood group biosynthesis

    SABIO-RK: Biochemical Reaction Kinetics Database

    More...
    SABIO-RKi
    P19526

    UniPathway: a resource for the exploration and annotation of metabolic pathways

    More...
    UniPathwayi
    UPA00378

    Protein family/group databases

    Carbohydrate-Active enZymes

    More...
    CAZyi
    GT11 Glycosyltransferase Family 11

    <p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
    Recommended name:
    Galactoside 2-alpha-L-fucosyltransferase 1 (EC:2.4.1.3441 Publication)
    Alternative name(s):
    Alpha(1,2)FT 1
    Blood group H alpha 2-fucosyltransferase
    Fucosyltransferase 1
    GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
    Name:FUT1
    Synonyms:H, HSC
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
    • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

    Organism-specific databases

    Human Gene Nomenclature Database

    More...
    HGNCi
    HGNC:4012 FUT1

    Online Mendelian Inheritance in Man (OMIM)

    More...
    MIMi
    211100 gene

    neXtProt; the human protein knowledge platform

    More...
    neXtProti
    NX_P19526

    <p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

    Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

    Topology

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 8CytoplasmicSequence analysis8
    <p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei9 – 25Helical; Signal-anchor for type II membrane proteinSequence analysisAdd BLAST17
    Topological domaini26 – 365LumenalSequence analysisAdd BLAST340

    Keywords - Cellular componenti

    Golgi apparatus, Membrane

    <p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

    Organism-specific databases

    DisGeNET

    More...
    DisGeNETi
    2523

    MalaCards human disease database

    More...
    MalaCardsi
    FUT1
    MIMi616754 phenotype

    Open Targets

    More...
    OpenTargetsi
    ENSG00000174951

    The Pharmacogenetics and Pharmacogenomics Knowledge Base

    More...
    PharmGKBi
    PA28428

    Polymorphism and mutation databases

    BioMuta curated single-nucleotide variation and disease association database

    More...
    BioMutai
    FUT1

    <p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

    Molecule processing

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001490951 – 365Galactoside 2-alpha-L-fucosyltransferase 1Add BLAST365

    Amino acid modifications

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi65N-linked (GlcNAc...) asparagineSequence analysis1
    Glycosylationi327N-linked (GlcNAc...) asparagineSequence analysis1

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    Encyclopedia of Proteome Dynamics

    More...
    EPDi
    P19526

    jPOST - Japan Proteome Standard Repository/Database

    More...
    jPOSTi
    P19526

    MassIVE - Mass Spectrometry Interactive Virtual Environment

    More...
    MassIVEi
    P19526

    PaxDb, a database of protein abundance averages across all three domains of life

    More...
    PaxDbi
    P19526

    PeptideAtlas

    More...
    PeptideAtlasi
    P19526

    PRoteomics IDEntifications database

    More...
    PRIDEi
    P19526

    ProteomicsDB human proteome resource

    More...
    ProteomicsDBi
    53671

    PTM databases

    iPTMnet integrated resource for PTMs in systems biology context

    More...
    iPTMneti
    P19526

    Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

    More...
    PhosphoSitePlusi
    P19526

    <p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

    Gene expression databases

    Bgee dataBase for Gene Expression Evolution

    More...
    Bgeei
    ENSG00000174951 Expressed in 135 organ(s), highest expression level in vagina

    ExpressionAtlas, Differential and Baseline Expression

    More...
    ExpressionAtlasi
    P19526 baseline and differential

    Genevisible search portal to normalized and curated expression data from Genevestigator

    More...
    Genevisiblei
    P19526 HS

    <p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

    Protein-protein interaction databases

    The Biological General Repository for Interaction Datasets (BioGrid)

    More...
    BioGridi
    108799, 21 interactors

    Protein interaction database and analysis system

    More...
    IntActi
    P19526, 16 interactors

    STRING: functional protein association networks

    More...
    STRINGi
    9606.ENSP00000312021

    <p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

    <p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

    Belongs to the glycosyltransferase 11 family.Curated

    Keywords - Domaini

    Signal-anchor, Transmembrane, Transmembrane helix

    Phylogenomic databases

    evolutionary genealogy of genes: Non-supervised Orthologous Groups

    More...
    eggNOGi
    ENOG410IFKR Eukaryota
    ENOG4111HG3 LUCA

    Ensembl GeneTree

    More...
    GeneTreei
    ENSGT00390000001450

    The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

    More...
    HOGENOMi
    HOG000261621

    InParanoid: Eukaryotic Ortholog Groups

    More...
    InParanoidi
    P19526

    KEGG Orthology (KO)

    More...
    KOi
    K00718

    Identification of Orthologs from Complete Genome Data

    More...
    OMAi
    FLHIHQD

    Database of Orthologous Groups

    More...
    OrthoDBi
    1006406at2759

    Database for complete collections of gene phylogenies

    More...
    PhylomeDBi
    P19526

    TreeFam database of animal gene trees

    More...
    TreeFami
    TF315810

    Family and domain databases

    Integrated resource of protein families, domains and functional sites

    More...
    InterProi
    View protein in InterPro
    IPR002516 Glyco_trans_11

    The PANTHER Classification System

    More...
    PANTHERi
    PTHR11927 PTHR11927, 1 hit

    Pfam protein domain database

    More...
    Pfami
    View protein in Pfam
    PF01531 Glyco_transf_11, 1 hit

    <p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

    P19526-1 [UniParc]FASTAAdd to basket
    « Hide
            10         20         30         40         50
    MWLRSHRQLC LAFLLVCVLS VIFFLHIHQD SFPHGLGLSI LCPDRRLVTP
    60 70 80 90 100
    PVAIFCLPGT AMGPNASSSC PQHPASLSGT WTVYPNGRFG NQMGQYATLL
    110 120 130 140 150
    ALAQLNGRRA FILPAMHAAL APVFRITLPV LAPEVDSRTP WRELQLHDWM
    160 170 180 190 200
    SEEYADLRDP FLKLSGFPCS WTFFHHLREQ IRREFTLHDH LREEAQSVLG
    210 220 230 240 250
    QLRLGRTGDR PRTFVGVHVR RGDYLQVMPQ RWKGVVGDSA YLRQAMDWFR
    260 270 280 290 300
    ARHEAPVFVV TSNGMEWCKE NIDTSQGDVT FAGDGQEATP WKDFALLTQC
    310 320 330 340 350
    NHTIMTIGTF GFWAAYLAGG DTVYLANFTL PDSEFLKIFK PEAAFLPEWV
    360
    GINADLSPLW TLAKP
    Length:365
    Mass (Da):41,251
    Last modified:February 1, 1991 - v1
    <p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4F4442EC375C9D9E
    GO

    <p>This subsection of the ‘Sequence’ section provides information on polymorphic variants. If the variant is associated with a disease state, the description of the latter can be found in the <a href="http://www.uniprot.org/manual/involvement_in_disease">'Involvement in disease'</a> subsection.<p><a href='/help/polymorphism' target='_top'>More...</a></p>Polymorphismi

    Genetic variations in FUT1 define the H blood group and are responsible for the Bombay and para-Bombay phenotypes [MIMi:616754]. Erythrocytes from individuals with the Bombay and para-Bombay blood group phenotypes are deficient in H antigens.4 Publications

    Natural variant

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_02226812A → V1 PublicationCorresponds to variant dbSNP:rs2071699Ensembl.1
    Natural variantiVAR_020536148D → Y Found in individuals with para-Bombay phenotype; allele H4. 1 PublicationCorresponds to variant dbSNP:rs747442925Ensembl.1
    Natural variantiVAR_003417154Y → C Found in individuals with Bombay phenotype. 1 Publication1
    Natural variantiVAR_020537154Y → H Found in individuals with para-Bombay phenotype; allele H5. 1 PublicationCorresponds to variant dbSNP:rs757349699Ensembl.1
    Natural variantiVAR_009708164L → H Found in individuals with para-Bombay phenotype. 1 PublicationCorresponds to variant dbSNP:rs104894687EnsemblClinVar.1
    Natural variantiVAR_003418171W → C Found in individuals with Bombay phenotype. 1 Publication1
    Natural variantiVAR_020538241Y → H Found in individuals with para-Bombay phenotype; allele H3. 1 PublicationCorresponds to variant dbSNP:rs765114567Ensembl.1
    Natural variantiVAR_009709242L → R Found in individuals with Bombay phenotype. 1 PublicationCorresponds to variant dbSNP:rs28934588EnsemblClinVar.1
    Natural variantiVAR_003419259V → E Found in individuals with Bombay phenotype. 1 Publication1
    Natural variantiVAR_003420315A → V Found in individuals with Bombay phenotype. 1 Publication1
    Natural variantiVAR_020539348E → K Found in individuals with para-Bombay phenotype; allele H5. 1 PublicationCorresponds to variant dbSNP:rs764739319Ensembl.1
    Natural variantiVAR_003421349W → C Found in individuals with Bombay phenotype. 1 PublicationCorresponds to variant dbSNP:rs1438752561Ensembl.1

    Sequence databases

    Select the link destinations:

    EMBL nucleotide sequence database

    More...
    EMBLi

    GenBank nucleotide sequence database

    More...
    GenBanki

    DNA Data Bank of Japan; a nucleotide sequence database

    More...
    DDBJi
    Links Updated
    M35531 mRNA Translation: AAA52639.1
    Z69587 Genomic DNA Translation: CAA93435.1
    AB004861 Genomic DNA Translation: BAA20558.1
    AB004862 Genomic DNA Translation: BAA20559.1
    AB004863 Genomic DNA Translation: BAA20560.1
    AY923051 Genomic DNA Translation: AAW82437.1
    BC074732 mRNA Translation: AAH74732.1

    The Consensus CDS (CCDS) project

    More...
    CCDSi
    CCDS12733.1

    Protein sequence database of the Protein Information Resource

    More...
    PIRi
    A36047

    NCBI Reference Sequences

    More...
    RefSeqi
    NP_000139.1, NM_000148.3
    NP_001316806.1, NM_001329877.1
    XP_016882042.1, XM_017026553.1

    Genome annotation databases

    Ensembl eukaryotic genome annotation project

    More...
    Ensembli
    ENST00000310160; ENSP00000312021; ENSG00000174951
    ENST00000645652; ENSP00000494643; ENSG00000174951

    Database of genes from NCBI RefSeq genomes

    More...
    GeneIDi
    2523

    KEGG: Kyoto Encyclopedia of Genes and Genomes

    More...
    KEGGi
    hsa:2523

    Keywords - Coding sequence diversityi

    Polymorphism

    <p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

    <p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

    <p>This subsection of the <a href="http://www.uniprot.org/manual/cross_references_section">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

    dbRBC/BGMUT

    Blood group antigen gene mutation database

    SeattleSNPs
    Functional Glycomics Gateway - GTase

    Fucosyltransferase 1

    Sequence databases

    Select the link destinations:
    EMBLi
    GenBanki
    DDBJi
    Links Updated
    M35531 mRNA Translation: AAA52639.1
    Z69587 Genomic DNA Translation: CAA93435.1
    AB004861 Genomic DNA Translation: BAA20558.1
    AB004862 Genomic DNA Translation: BAA20559.1
    AB004863 Genomic DNA Translation: BAA20560.1
    AY923051 Genomic DNA Translation: AAW82437.1
    BC074732 mRNA Translation: AAH74732.1
    CCDSiCCDS12733.1
    PIRiA36047
    RefSeqiNP_000139.1, NM_000148.3
    NP_001316806.1, NM_001329877.1
    XP_016882042.1, XM_017026553.1

    3D structure databases

    Database of comparative protein structure models

    More...
    ModBasei
    Search...

    SWISS-MODEL Interactive Workspace

    More...
    SWISS-MODEL-Workspacei
    Submit a new modelling project...

    Protein-protein interaction databases

    BioGridi108799, 21 interactors
    IntActiP19526, 16 interactors
    STRINGi9606.ENSP00000312021

    Protein family/group databases

    CAZyiGT11 Glycosyltransferase Family 11

    PTM databases

    iPTMnetiP19526
    PhosphoSitePlusiP19526

    Polymorphism and mutation databases

    BioMutaiFUT1

    Proteomic databases

    EPDiP19526
    jPOSTiP19526
    MassIVEiP19526
    PaxDbiP19526
    PeptideAtlasiP19526
    PRIDEiP19526
    ProteomicsDBi53671

    Protocols and materials databases

    The DNASU plasmid repository

    More...
    DNASUi
    2523
    Structural Biology KnowledgebaseSearch...

    Genome annotation databases

    EnsembliENST00000310160; ENSP00000312021; ENSG00000174951
    ENST00000645652; ENSP00000494643; ENSG00000174951
    GeneIDi2523
    KEGGihsa:2523

    Organism-specific databases

    Comparative Toxicogenomics Database

    More...
    CTDi
    2523
    DisGeNETi2523

    GeneCards: human genes, protein and diseases

    More...
    GeneCardsi
    FUT1
    HGNCiHGNC:4012 FUT1
    MalaCardsiFUT1
    MIMi211100 gene
    616754 phenotype
    neXtProtiNX_P19526
    OpenTargetsiENSG00000174951
    PharmGKBiPA28428

    GenAtlas: human gene database

    More...
    GenAtlasi
    Search...

    Phylogenomic databases

    eggNOGiENOG410IFKR Eukaryota
    ENOG4111HG3 LUCA
    GeneTreeiENSGT00390000001450
    HOGENOMiHOG000261621
    InParanoidiP19526
    KOiK00718
    OMAiFLHIHQD
    OrthoDBi1006406at2759
    PhylomeDBiP19526
    TreeFamiTF315810

    Enzyme and pathway databases

    UniPathwayiUPA00378
    BioCyciMetaCyc:HS10855-MONOMER
    BRENDAi2.4.1.69 2681
    ReactomeiR-HSA-9033807 ABO blood group biosynthesis
    SABIO-RKiP19526

    Miscellaneous databases

    The Gene Wiki collection of pages on human genes and proteins

    More...
    GeneWikii
    FUT1

    Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

    More...
    GenomeRNAii
    2523

    Pharos

    More...
    Pharosi
    P19526

    Protein Ontology

    More...
    PROi
    PR:P19526

    The Stanford Online Universal Resource for Clones and ESTs

    More...
    SOURCEi
    Search...

    Gene expression databases

    BgeeiENSG00000174951 Expressed in 135 organ(s), highest expression level in vagina
    ExpressionAtlasiP19526 baseline and differential
    GenevisibleiP19526 HS

    Family and domain databases

    InterProiView protein in InterPro
    IPR002516 Glyco_trans_11
    PANTHERiPTHR11927 PTHR11927, 1 hit
    PfamiView protein in Pfam
    PF01531 Glyco_transf_11, 1 hit

    ProtoNet; Automatic hierarchical classification of proteins

    More...
    ProtoNeti
    Search...

    MobiDB: a database of protein disorder and mobility annotations

    More...
    MobiDBi
    Search...

    <p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

    <p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFUT1_HUMAN
    <p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P19526
    Secondary accession number(s): O14505, O14506, O14507
    <p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1991
    Last sequence update: February 1, 1991
    Last modified: September 18, 2019
    This is version 174 of the entry and version 1 of the sequence. See complete history.
    <p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    <p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Human chromosome 19
      Human chromosome 19: entries, gene names and cross-references to MIM
    3. Blood group antigen proteins
      Nomenclature of blood group antigens and list of entries
    4. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    5. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    6. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    7. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    UniProt is an ELIXIR core data resource
    Main funding by: National Institutes of Health

    We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

    Do not show this banner again