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Entry version 185 (29 Sep 2021)
Sequence version 1 (01 Feb 1991)
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Protein

Galactoside alpha-(1,2)-fucosyltransferase 1

Gene

FUT1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the terminal galactose residue of glycoconjugates through an alpha(1,2) linkage leading to H antigen synthesis that is an intermediate substrate in the synthesis of ABO blood group antigens (PubMed:2118655).

H antigen is essential for maturation of the glomerular layer of the main olfactory bulb, in cell migration and early cell-cell contacts during tumor associated angiogenesis (PubMed:18205178).

Preferentially fucosylates soluble lactose and to a lesser extent fucosylates glycolipids gangliosides GA1 and GM1a (By similarity).

By similarity2 Publications

Miscellaneous

There are two genes (FUT1 and FUT2) which encode galactoside 2-L-fucosyltransferase. They are expressed in a tissue-specific manner with expression restricted to cells of mesodermal or endodermal origin respectively.Curated

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

  1. KM=2.4 mM for phenyl beta-D-galactoside1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: protein glycosylation

This protein is involved in the pathway protein glycosylation, which is part of Protein modification.1 Publication
View all proteins of this organism that are known to be involved in the pathway protein glycosylation and in Protein modification.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionBlood group antigen, Glycosyltransferase, Transferase
Biological processLipid metabolism

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

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BioCyci
MetaCyc:HS10855-MONOMER

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
2.4.1.344, 2681
2.4.1.69, 2681

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
P19526

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-9033807, ABO blood group biosynthesis

SABIO-RK: Biochemical Reaction Kinetics Database

More...
SABIO-RKi
P19526

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00378

Protein family/group databases

Carbohydrate-Active enZymes

More...
CAZyi
GT11, Glycosyltransferase Family 11

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Galactoside alpha-(1,2)-fucosyltransferase 1Curated
Alternative name(s):
Alpha(1,2)FT 1
Blood group H alpha 2-fucosyltransferase
Fucosyltransferase 1
GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1
Type 1 galactoside alpha-(1,2)-fucosyltransferase FUT1By similarity (EC:2.4.1.69By similarity)
Type 2 galactoside alpha-(1,2)-fucosyltransferase FUT1Curated (EC:2.4.1.3441 Publication)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FUT1Imported
Synonyms:H, HSC
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:4012, FUT1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
211100, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P19526

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000174951

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 8CytoplasmicSequence analysis8
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei9 – 25Helical; Signal-anchor for type II membrane proteinSequence analysisAdd BLAST17
Topological domaini26 – 365LumenalSequence analysisAdd BLAST340

Keywords - Cellular componenti

Golgi apparatus, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
2523

MalaCards human disease database

More...
MalaCardsi
FUT1
MIMi616754, phenotype

Open Targets

More...
OpenTargetsi
ENSG00000174951

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA28428

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
P19526, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
FUT1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001490951 – 365Galactoside alpha-(1,2)-fucosyltransferase 1Add BLAST365

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi65N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi327N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P19526

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
P19526

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P19526

PeptideAtlas

More...
PeptideAtlasi
P19526

PRoteomics IDEntifications database

More...
PRIDEi
P19526

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
53671

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...
GlyGeni
P19526, 2 sites

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P19526

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P19526

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Increased by TNF.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000174951, Expressed in vagina and 145 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P19526, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P19526, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000174951, Tissue enhanced (pancreas)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
108799, 21 interactors

Protein interaction database and analysis system

More...
IntActi
P19526, 16 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000312021

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
P19526, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
P19526

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the glycosyltransferase 11 family.Curated

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502S316, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000001450

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_043399_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P19526

Identification of Orthologs from Complete Genome Data

More...
OMAi
MWPPSHR

Database of Orthologous Groups

More...
OrthoDBi
1006406at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P19526

TreeFam database of animal gene trees

More...
TreeFami
TF315810

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002516, Glyco_trans_11

The PANTHER Classification System

More...
PANTHERi
PTHR11927, PTHR11927, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01531, Glyco_transf_11, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P19526-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MWLRSHRQLC LAFLLVCVLS VIFFLHIHQD SFPHGLGLSI LCPDRRLVTP
60 70 80 90 100
PVAIFCLPGT AMGPNASSSC PQHPASLSGT WTVYPNGRFG NQMGQYATLL
110 120 130 140 150
ALAQLNGRRA FILPAMHAAL APVFRITLPV LAPEVDSRTP WRELQLHDWM
160 170 180 190 200
SEEYADLRDP FLKLSGFPCS WTFFHHLREQ IRREFTLHDH LREEAQSVLG
210 220 230 240 250
QLRLGRTGDR PRTFVGVHVR RGDYLQVMPQ RWKGVVGDSA YLRQAMDWFR
260 270 280 290 300
ARHEAPVFVV TSNGMEWCKE NIDTSQGDVT FAGDGQEATP WKDFALLTQC
310 320 330 340 350
NHTIMTIGTF GFWAAYLAGG DTVYLANFTL PDSEFLKIFK PEAAFLPEWV
360
GINADLSPLW TLAKP
Length:365
Mass (Da):41,251
Last modified:February 1, 1991 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4F4442EC375C9D9E
GO

<p>This subsection of the 'Sequence' section provides information on polymorphic variants. If the variant is associated with a disease state, the description of the latter can be found in the <a href="http://www.uniprot.org/manual/involvement_in_disease">'Involvement in disease'</a> subsection.<p><a href='/help/polymorphism' target='_top'>More...</a></p>Polymorphismi

Genetic variations in FUT1 define the H blood group and are responsible for the Bombay and para-Bombay phenotypes [MIMi:616754]. Erythrocytes from individuals with the Bombay and para-Bombay blood group phenotypes are deficient in H antigens.4 Publications

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_02226812A → V1 PublicationCorresponds to variant dbSNP:rs2071699Ensembl.1
Natural variantiVAR_020536148D → Y Found in individuals with para-Bombay phenotype; allele H4. 1 PublicationCorresponds to variant dbSNP:rs747442925Ensembl.1
Natural variantiVAR_003417154Y → C Found in individuals with Bombay phenotype. 1 Publication1
Natural variantiVAR_020537154Y → H Found in individuals with para-Bombay phenotype; allele H5. 1 PublicationCorresponds to variant dbSNP:rs757349699Ensembl.1
Natural variantiVAR_009708164L → H Found in individuals with para-Bombay phenotype. 1 PublicationCorresponds to variant dbSNP:rs104894687EnsemblClinVar.1
Natural variantiVAR_003418171W → C Found in individuals with Bombay phenotype. 1 Publication1
Natural variantiVAR_020538241Y → H Found in individuals with para-Bombay phenotype; allele H3. 1 PublicationCorresponds to variant dbSNP:rs765114567Ensembl.1
Natural variantiVAR_009709242L → R Found in individuals with Bombay phenotype. 1 PublicationCorresponds to variant dbSNP:rs28934588EnsemblClinVar.1
Natural variantiVAR_003419259V → E Found in individuals with Bombay phenotype. 1 Publication1
Natural variantiVAR_003420315A → V Found in individuals with Bombay phenotype. 1 Publication1
Natural variantiVAR_020539348E → K Found in individuals with para-Bombay phenotype; allele H5. 1 PublicationCorresponds to variant dbSNP:rs764739319Ensembl.1
Natural variantiVAR_003421349W → C Found in individuals with Bombay phenotype. 1 PublicationCorresponds to variant dbSNP:rs1438752561Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
M35531 mRNA Translation: AAA52639.1
Z69587 Genomic DNA Translation: CAA93435.1
AB004861 Genomic DNA Translation: BAA20558.1
AB004862 Genomic DNA Translation: BAA20559.1
AB004863 Genomic DNA Translation: BAA20560.1
AY923051 Genomic DNA Translation: AAW82437.1
AC009002 Genomic DNA No translation available.
BC074732 mRNA Translation: AAH74732.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS12733.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A36047

NCBI Reference Sequences

More...
RefSeqi
NP_000139.1, NM_000148.3
NP_001316806.1, NM_001329877.1
XP_016882042.1, XM_017026553.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000645652; ENSP00000494643; ENSG00000174951

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
2523

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:2523

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross_references_section">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

dbRBC/BGMUT

Blood group antigen gene mutation database

SeattleSNPs
Functional Glycomics Gateway - GTase

Fucosyltransferase 1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M35531 mRNA Translation: AAA52639.1
Z69587 Genomic DNA Translation: CAA93435.1
AB004861 Genomic DNA Translation: BAA20558.1
AB004862 Genomic DNA Translation: BAA20559.1
AB004863 Genomic DNA Translation: BAA20560.1
AY923051 Genomic DNA Translation: AAW82437.1
AC009002 Genomic DNA No translation available.
BC074732 mRNA Translation: AAH74732.1
CCDSiCCDS12733.1
PIRiA36047
RefSeqiNP_000139.1, NM_000148.3
NP_001316806.1, NM_001329877.1
XP_016882042.1, XM_017026553.1

3D structure databases

SMRiP19526
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi108799, 21 interactors
IntActiP19526, 16 interactors
STRINGi9606.ENSP00000312021

Protein family/group databases

CAZyiGT11, Glycosyltransferase Family 11

PTM databases

GlyGeniP19526, 2 sites
iPTMnetiP19526
PhosphoSitePlusiP19526

Genetic variation databases

BioMutaiFUT1

Proteomic databases

EPDiP19526
MassIVEiP19526
PaxDbiP19526
PeptideAtlasiP19526
PRIDEiP19526
ProteomicsDBi53671

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
31803, 138 antibodies

The DNASU plasmid repository

More...
DNASUi
2523

Genome annotation databases

EnsembliENST00000645652; ENSP00000494643; ENSG00000174951
GeneIDi2523
KEGGihsa:2523

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
2523
DisGeNETi2523

GeneCards: human genes, protein and diseases

More...
GeneCardsi
FUT1
HGNCiHGNC:4012, FUT1
HPAiENSG00000174951, Tissue enhanced (pancreas)
MalaCardsiFUT1
MIMi211100, gene
616754, phenotype
neXtProtiNX_P19526
OpenTargetsiENSG00000174951
PharmGKBiPA28428
VEuPathDBiHostDB:ENSG00000174951

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502S316, Eukaryota
GeneTreeiENSGT00390000001450
HOGENOMiCLU_043399_0_0_1
InParanoidiP19526
OMAiMWPPSHR
OrthoDBi1006406at2759
PhylomeDBiP19526
TreeFamiTF315810

Enzyme and pathway databases

UniPathwayiUPA00378
BioCyciMetaCyc:HS10855-MONOMER
BRENDAi2.4.1.344, 2681
2.4.1.69, 2681
PathwayCommonsiP19526
ReactomeiR-HSA-9033807, ABO blood group biosynthesis
SABIO-RKiP19526

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
2523, 15 hits in 1016 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
FUT1, human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
FUT1

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
2523
PharosiP19526, Tbio

Protein Ontology

More...
PROi
PR:P19526
RNActiP19526, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000174951, Expressed in vagina and 145 other tissues
ExpressionAtlasiP19526, baseline and differential
GenevisibleiP19526, HS

Family and domain databases

InterProiView protein in InterPro
IPR002516, Glyco_trans_11
PANTHERiPTHR11927, PTHR11927, 1 hit
PfamiView protein in Pfam
PF01531, Glyco_transf_11, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFUT1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P19526
Secondary accession number(s): O14505, O14506, O14507
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1991
Last sequence update: February 1, 1991
Last modified: September 29, 2021
This is version 185 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Blood group antigen proteins
    Nomenclature of blood group antigens and list of entries
  2. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  3. Human entries with genetic variants
    List of human entries with genetic variants
  4. Human variants curated from literature reports
    Index of human variants curated from literature reports
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  6. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  7. SIMILARITY comments
    Index of protein domains and families
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