UniProtKB - P19320 (VCAM1_HUMAN)
Vascular cell adhesion protein 1
VCAM1
Functioni
Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.
GO - Molecular functioni
- cell adhesion molecule binding Source: BHF-UCL
- integrin binding Source: BHF-UCL
- primary amine oxidase activity Source: UniProtKB
GO - Biological processi
- acute inflammatory response Source: Ensembl
- aging Source: Ensembl
- amine metabolic process Source: UniProtKB
- B cell differentiation Source: BHF-UCL
- calcium-mediated signaling using intracellular calcium source Source: UniProtKB
- cardiac neuron differentiation Source: Ensembl
- cell adhesion Source: BHF-UCL
- cell-cell adhesion in response to extracellular stimulus Source: ARUK-UCL
- cell chemotaxis Source: Ensembl
- cell-matrix adhesion Source: UniProtKB
- cellular response to amyloid-beta Source: ARUK-UCL
- cellular response to tumor necrosis factor Source: Ensembl
- cellular response to vascular endothelial growth factor stimulus Source: Ensembl
- chronic inflammatory response Source: Ensembl
- heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules Source: BHF-UCL
- heterotypic cell-cell adhesion Source: ARUK-UCL
- innervation Source: Ensembl
- leukocyte cell-cell adhesion Source: BHF-UCL
- leukocyte tethering or rolling Source: UniProtKB
- membrane to membrane docking Source: BHF-UCL
- positive regulation of T cell proliferation Source: BHF-UCL
- response to ethanol Source: Ensembl
- response to hypoxia Source: Ensembl
- response to ionizing radiation Source: Ensembl
- response to lipopolysaccharide Source: Ensembl
- response to nicotine Source: Ensembl
- response to nutrient Source: Ensembl
- response to zinc ion Source: Ensembl
Keywordsi
Biological process | Cell adhesion |
Enzyme and pathway databases
PathwayCommonsi | P19320 |
Reactomei | R-HSA-198933, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-216083, Integrin cell surface interactions R-HSA-6785807, Interleukin-4 and Interleukin-13 signaling R-HSA-877300, Interferon gamma signaling |
SignaLinki | P19320 |
SIGNORi | P19320 |
Names & Taxonomyi
Protein namesi | Recommended name: Vascular cell adhesion protein 1Short name: V-CAM 1 Short name: VCAM-1 Alternative name(s): INCAM-100 CD_antigen: CD106 |
Gene namesi | Name:VCAM1 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:12663, VCAM1 |
MIMi | 192225, gene |
neXtProti | NX_P19320 |
VEuPathDBi | HostDB:ENSG00000162692 |
Subcellular locationi
Other locations
Cytoskeleton
- podosome Source: BHF-UCL
Endoplasmic reticulum
- endoplasmic reticulum Source: UniProtKB
Endosome
- early endosome Source: UniProtKB
Extracellular region or secreted
- extracellular exosome Source: UniProtKB
- extracellular space Source: BHF-UCL
Golgi apparatus
- Golgi apparatus Source: UniProtKB
Plasma Membrane
- alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex Source: BHF-UCL
- external side of plasma membrane Source: BHF-UCL
- integral component of plasma membrane Source: GO_Central
- plasma membrane Source: Reactome
- sarcolemma Source: Ensembl
Other locations
- apical part of cell Source: BHF-UCL
- cell surface Source: UniProtKB
- filopodium Source: BHF-UCL
- microvillus Source: BHF-UCL
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 25 – 698 | ExtracellularSequence analysisAdd BLAST | 674 | |
Transmembranei | 699 – 720 | HelicalSequence analysisAdd BLAST | 22 | |
Topological domaini | 721 – 739 | CytoplasmicSequence analysisAdd BLAST | 19 |
Keywords - Cellular componenti
MembranePathology & Biotechi
Organism-specific databases
DisGeNETi | 7412 |
OpenTargetsi | ENSG00000162692 |
PharmGKBi | PA37286 |
Miscellaneous databases
Pharosi | P19320, Tchem |
Chemistry databases
ChEMBLi | CHEMBL3735 |
DrugBanki | DB01136, Carvedilol DB11338, Clove oil DB00898, Ethanol DB05399, Succinobucol |
Genetic variation databases
BioMutai | VCAM1 |
DMDMi | 137560 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 24 | 1 PublicationAdd BLAST | 24 | |
ChainiPRO_0000014997 | 25 – 739 | Vascular cell adhesion protein 1Add BLAST | 715 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 47 ↔ 95 | 1 Publication | ||
Disulfide bondi | 52 ↔ 99 | 1 Publication | ||
Disulfide bondi | 137 ↔ 195 | 1 Publication | ||
Disulfide bondi | 246 ↔ 291 | PROSITE-ProRule annotation | ||
Glycosylationi | 273 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 335 ↔ 383 | PROSITE-ProRule annotation | ||
Glycosylationi | 365 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 417 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 463 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 531 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 534 ↔ 579 | PROSITE-ProRule annotation | ||
Glycosylationi | 561 | N-linked (GlcNAc...) asparagine1 Publication | 1 |
Post-translational modificationi
Keywords - PTMi
Disulfide bond, GlycoproteinProteomic databases
jPOSTi | P19320 |
MassIVEi | P19320 |
MaxQBi | P19320 |
PaxDbi | P19320 |
PeptideAtlasi | P19320 |
PRIDEi | P19320 |
ProteomicsDBi | 19636 53645 [P19320-1] 53646 [P19320-2] |
PTM databases
GlyConnecti | 1984, 6 N-Linked glycans (2 sites) |
GlyGeni | P19320, 10 sites, 6 N-linked glycans (2 sites), 1 O-linked glycan (3 sites) |
iPTMneti | P19320 |
PhosphoSitePlusi | P19320 |
Expressioni
Tissue specificityi
Inductioni
Gene expression databases
Bgeei | ENSG00000162692, Expressed in tendon and 214 other tissues |
ExpressionAtlasi | P19320, baseline and differential |
Genevisiblei | P19320, HS |
Organism-specific databases
HPAi | ENSG00000162692, Tissue enriched (lymphoid) |
Interactioni
GO - Molecular functioni
- cell adhesion molecule binding Source: BHF-UCL
- integrin binding Source: BHF-UCL
Protein-protein interaction databases
BioGRIDi | 113255, 463 interactors |
CORUMi | P19320 |
IntActi | P19320, 638 interactors |
MINTi | P19320 |
STRINGi | 9606.ENSP00000294728 |
Chemistry databases
BindingDBi | P19320 |
Miscellaneous databases
RNActi | P19320, protein |
Structurei
Secondary structure
3D structure databases
SMRi | P19320 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P19320 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 25 – 105 | Ig-like C2-type 1Add BLAST | 81 | |
Domaini | 109 – 212 | Ig-like C2-type 2Add BLAST | 104 | |
Domaini | 223 – 309 | Ig-like C2-type 3Add BLAST | 87 | |
Domaini | 312 – 399 | Ig-like C2-type 4Add BLAST | 88 | |
Domaini | 408 – 506 | Ig-like C2-type 5Add BLAST | 99 | |
Domaini | 511 – 595 | Ig-like C2-type 6Add BLAST | 85 | |
Domaini | 600 – 684 | Ig-like C2-type 7Add BLAST | 85 |
Domaini
Keywords - Domaini
Immunoglobulin domain, Repeat, Signal, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | ENOG502QSKQ, Eukaryota |
GeneTreei | ENSGT00940000156511 |
InParanoidi | P19320 |
OMAi | YTIHKAQ |
OrthoDBi | 544376at2759 |
PhylomeDBi | P19320 |
TreeFami | TF333571 |
Family and domain databases
Gene3Di | 2.60.40.10, 7 hits |
InterProi | View protein in InterPro IPR003987, ICAM_VCAM_N IPR007110, Ig-like_dom IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR008424, Ig_C2-set IPR013098, Ig_I-set IPR003599, Ig_sub IPR003598, Ig_sub2 IPR013106, Ig_V-set IPR013151, Immunoglobulin IPR003989, VCAM-1 |
PANTHERi | PTHR13771:SF14, PTHR13771:SF14, 6 hits |
Pfami | View protein in Pfam PF05790, C2-set, 2 hits PF07679, I-set, 3 hits PF00047, ig, 1 hit |
PRINTSi | PR01472, ICAMVCAM1 PR01474, VCAM1 |
SMARTi | View protein in SMART SM00409, IG, 5 hits SM00408, IGc2, 5 hits SM00406, IGv, 2 hits |
SUPFAMi | SSF48726, SSF48726, 7 hits |
PROSITEi | View protein in PROSITE PS50835, IG_LIKE, 5 hits |
s (3+)i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
This entry describes 3 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 3 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MPGKMVVILG ASNILWIMFA ASQAFKIETT PESRYLAQIG DSVSLTCSTT
60 70 80 90 100
GCESPFFSWR TQIDSPLNGK VTNEGTTSTL TMNPVSFGNE HSYLCTATCE
110 120 130 140 150
SRKLEKGIQV EIYSFPKDPE IHLSGPLEAG KPITVKCSVA DVYPFDRLEI
160 170 180 190 200
DLLKGDHLMK SQEFLEDADR KSLETKSLEV TFTPVIEDIG KVLVCRAKLH
210 220 230 240 250
IDEMDSVPTV RQAVKELQVY ISPKNTVISV NPSTKLQEGG SVTMTCSSEG
260 270 280 290 300
LPAPEIFWSK KLDNGNLQHL SGNATLTLIA MRMEDSGIYV CEGVNLIGKN
310 320 330 340 350
RKEVELIVQE KPFTVEISPG PRIAAQIGDS VMLTCSVMGC ESPSFSWRTQ
360 370 380 390 400
IDSPLSGKVR SEGTNSTLTL SPVSFENEHS YLCTVTCGHK KLEKGIQVEL
410 420 430 440 450
YSFPRDPEIE MSGGLVNGSS VTVSCKVPSV YPLDRLEIEL LKGETILENI
460 470 480 490 500
EFLEDTDMKS LENKSLEMTF IPTIEDTGKA LVCQAKLHID DMEFEPKQRQ
510 520 530 540 550
STQTLYVNVA PRDTTVLVSP SSILEEGSSV NMTCLSQGFP APKILWSRQL
560 570 580 590 600
PNGELQPLSE NATLTLISTK MEDSGVYLCE GINQAGRSRK EVELIIQVTP
610 620 630 640 650
KDIKLTAFPS ESVKEGDTVI ISCTCGNVPE TWIILKKKAE TGDTVLKSID
660 670 680 690 700
GAYTIRKAQL KDAGVYECES KNKVGSQLRS LTLDVQGREN NKDYFSPELL
710 720 730
VLYFASSLII PAIGMIIYFA RKANMKGSYS LVEAQKSKV
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketE9PDD2 | E9PDD2_HUMAN | Vascular cell adhesion protein 1 | VCAM1 | 540 | Annotation score: | ||
A0A3B3ISS8 | A0A3B3ISS8_HUMAN | Vascular cell adhesion protein 1 | VCAM1 | 116 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 182 | F → G (PubMed:1377228).Curated | 1 | |
Sequence conflicti | 402 | S → T (PubMed:1707234).Curated | 1 | |
Sequence conflicti | 728 | S → P in BAG59286 (PubMed:14702039).Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_049951 | 18 | M → I. Corresponds to variant dbSNP:rs34228330Ensembl. | 1 | |
Natural variantiVAR_014309 | 318 | S → F1 PublicationCorresponds to variant dbSNP:rs3783611Ensembl. | 1 | |
Natural variantiVAR_014310 | 384 | T → A1 PublicationCorresponds to variant dbSNP:rs3783612Ensembl. | 1 | |
Natural variantiVAR_014311 | 413 | G → A1 PublicationCorresponds to variant dbSNP:rs3783613Ensembl. | 1 | |
Natural variantiVAR_049952 | 421 | V → I. Corresponds to variant dbSNP:rs34100871Ensembl. | 1 | |
Natural variantiVAR_049953 | 488 | H → R. Corresponds to variant dbSNP:rs34199378EnsemblClinVar. | 1 | |
Natural variantiVAR_014312 | 716 | I → L1 PublicationCorresponds to variant dbSNP:rs3783615Ensembl. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_044636 | 52 – 113 | Missing in isoform 3. 1 PublicationAdd BLAST | 62 | |
Alternative sequenceiVSP_002580 | 310 – 402 | EKPFT…VELYS → A in isoform 2. 1 PublicationAdd BLAST | 93 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M30257 mRNA Translation: AAA51917.1 X53051 mRNA Translation: CAA37218.1 M60335 mRNA Translation: AAA61269.1 M73255 Genomic DNA Translation: AAA61270.1 AF536818 Genomic DNA Translation: AAM96190.1 AK291732 mRNA Translation: BAF84421.1 AK296692 mRNA Translation: BAG59286.1 AC093428 Genomic DNA No translation available. CH471097 Genomic DNA Translation: EAW72950.1 BC017276 mRNA Translation: AAH17276.3 BC068490 mRNA Translation: AAH68490.2 BC085003 mRNA Translation: AAH85003.1 M92431 Genomic DNA No translation available. |
CCDSi | CCDS55617.1 [P19320-3] CCDS773.1 [P19320-1] CCDS774.1 [P19320-2] |
PIRi | A41288 B41288 |
RefSeqi | NP_001069.1, NM_001078.3 [P19320-1] NP_001186763.1, NM_001199834.1 [P19320-3] NP_542413.1, NM_080682.2 [P19320-2] |
Genome annotation databases
Ensembli | ENST00000294728; ENSP00000294728; ENSG00000162692 ENST00000347652; ENSP00000304611; ENSG00000162692 [P19320-2] ENST00000370119; ENSP00000359137; ENSG00000162692 [P19320-3] |
GeneIDi | 7412 |
KEGGi | hsa:7412 |
MANE-Selecti | ENST00000294728.7; ENSP00000294728.2; NM_001078.4; NP_001069.1 |
UCSCi | uc001dti.5, human [P19320-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Web resourcesi
Wikipedia VCAM1 entry |
SeattleSNPs |
Functional Glycomics Gateway - Glycan Binding VCAM-1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M30257 mRNA Translation: AAA51917.1 X53051 mRNA Translation: CAA37218.1 M60335 mRNA Translation: AAA61269.1 M73255 Genomic DNA Translation: AAA61270.1 AF536818 Genomic DNA Translation: AAM96190.1 AK291732 mRNA Translation: BAF84421.1 AK296692 mRNA Translation: BAG59286.1 AC093428 Genomic DNA No translation available. CH471097 Genomic DNA Translation: EAW72950.1 BC017276 mRNA Translation: AAH17276.3 BC068490 mRNA Translation: AAH68490.2 BC085003 mRNA Translation: AAH85003.1 M92431 Genomic DNA No translation available. |
CCDSi | CCDS55617.1 [P19320-3] CCDS773.1 [P19320-1] CCDS774.1 [P19320-2] |
PIRi | A41288 B41288 |
RefSeqi | NP_001069.1, NM_001078.3 [P19320-1] NP_001186763.1, NM_001199834.1 [P19320-3] NP_542413.1, NM_080682.2 [P19320-2] |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1IJ9 | X-ray | 3.00 | A | 25-220 | [»] | |
1VCA | X-ray | 1.80 | A/B | 25-226 | [»] | |
1VSC | X-ray | 1.90 | A/B | 25-219 | [»] | |
SMRi | P19320 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 113255, 463 interactors |
CORUMi | P19320 |
IntActi | P19320, 638 interactors |
MINTi | P19320 |
STRINGi | 9606.ENSP00000294728 |
Chemistry databases
BindingDBi | P19320 |
ChEMBLi | CHEMBL3735 |
DrugBanki | DB01136, Carvedilol DB11338, Clove oil DB00898, Ethanol DB05399, Succinobucol |
PTM databases
GlyConnecti | 1984, 6 N-Linked glycans (2 sites) |
GlyGeni | P19320, 10 sites, 6 N-linked glycans (2 sites), 1 O-linked glycan (3 sites) |
iPTMneti | P19320 |
PhosphoSitePlusi | P19320 |
Genetic variation databases
BioMutai | VCAM1 |
DMDMi | 137560 |
Proteomic databases
jPOSTi | P19320 |
MassIVEi | P19320 |
MaxQBi | P19320 |
PaxDbi | P19320 |
PeptideAtlasi | P19320 |
PRIDEi | P19320 |
ProteomicsDBi | 19636 53645 [P19320-1] 53646 [P19320-2] |
Protocols and materials databases
ABCDi | P19320, 2 sequenced antibodies |
Antibodypediai | 3955, 2152 antibodies from 52 providers |
CPTCi | P19320, 1 antibody |
DNASUi | 7412 |
Genome annotation databases
Ensembli | ENST00000294728; ENSP00000294728; ENSG00000162692 ENST00000347652; ENSP00000304611; ENSG00000162692 [P19320-2] ENST00000370119; ENSP00000359137; ENSG00000162692 [P19320-3] |
GeneIDi | 7412 |
KEGGi | hsa:7412 |
MANE-Selecti | ENST00000294728.7; ENSP00000294728.2; NM_001078.4; NP_001069.1 |
UCSCi | uc001dti.5, human [P19320-1] |
Organism-specific databases
CTDi | 7412 |
DisGeNETi | 7412 |
GeneCardsi | VCAM1 |
HGNCi | HGNC:12663, VCAM1 |
HPAi | ENSG00000162692, Tissue enriched (lymphoid) |
MIMi | 192225, gene |
neXtProti | NX_P19320 |
OpenTargetsi | ENSG00000162692 |
PharmGKBi | PA37286 |
VEuPathDBi | HostDB:ENSG00000162692 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | ENOG502QSKQ, Eukaryota |
GeneTreei | ENSGT00940000156511 |
InParanoidi | P19320 |
OMAi | YTIHKAQ |
OrthoDBi | 544376at2759 |
PhylomeDBi | P19320 |
TreeFami | TF333571 |
Enzyme and pathway databases
PathwayCommonsi | P19320 |
Reactomei | R-HSA-198933, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-216083, Integrin cell surface interactions R-HSA-6785807, Interleukin-4 and Interleukin-13 signaling R-HSA-877300, Interferon gamma signaling |
SignaLinki | P19320 |
SIGNORi | P19320 |
Miscellaneous databases
BioGRID-ORCSi | 7412, 8 hits in 1044 CRISPR screens |
ChiTaRSi | VCAM1, human |
EvolutionaryTracei | P19320 |
GeneWikii | VCAM-1 |
GenomeRNAii | 7412 |
Pharosi | P19320, Tchem |
PROi | PR:P19320 |
RNActi | P19320, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000162692, Expressed in tendon and 214 other tissues |
ExpressionAtlasi | P19320, baseline and differential |
Genevisiblei | P19320, HS |
Family and domain databases
Gene3Di | 2.60.40.10, 7 hits |
InterProi | View protein in InterPro IPR003987, ICAM_VCAM_N IPR007110, Ig-like_dom IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR008424, Ig_C2-set IPR013098, Ig_I-set IPR003599, Ig_sub IPR003598, Ig_sub2 IPR013106, Ig_V-set IPR013151, Immunoglobulin IPR003989, VCAM-1 |
PANTHERi | PTHR13771:SF14, PTHR13771:SF14, 6 hits |
Pfami | View protein in Pfam PF05790, C2-set, 2 hits PF07679, I-set, 3 hits PF00047, ig, 1 hit |
PRINTSi | PR01472, ICAMVCAM1 PR01474, VCAM1 |
SMARTi | View protein in SMART SM00409, IG, 5 hits SM00408, IGc2, 5 hits SM00406, IGv, 2 hits |
SUPFAMi | SSF48726, SSF48726, 7 hits |
PROSITEi | View protein in PROSITE PS50835, IG_LIKE, 5 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | VCAM1_HUMAN | |
Accessioni | P19320Primary (citable) accession number: P19320 Secondary accession number(s): A8K6R7 Q6NUP8 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1990 |
Last sequence update: | November 1, 1990 | |
Last modified: | February 23, 2022 | |
This is version 247 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencing, Reference proteomeDocuments
- Human cell differentiation molecules
CD nomenclature of surface proteins of human leucocytes and list of entries - Human chromosome 1
Human chromosome 1: entries, gene names and cross-references to MIM - Human entries with genetic variants
List of human entries with genetic variants - Human variants curated from literature reports
Index of human variants curated from literature reports - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references