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Protein

Acidic endochitinase

Gene

CHIB1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

This protein functions as a defense against chitin containing fungal pathogens.

Catalytic activityi

Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei156Proton donorPROSITE-ProRule annotation1

GO - Molecular functioni

  • beta-glucosidase activity Source: TAIR
  • chitinase activity Source: GO_Central
  • chitin binding Source: GO_Central
  • lysozyme activity Source: TAIR

GO - Biological processi

  • cellular response to water deprivation Source: TAIR
  • chitin catabolic process Source: GO_Central
  • pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response Source: TAIR
  • polysaccharide catabolic process Source: UniProtKB-KW
  • response to cold Source: TAIR
  • response to light intensity Source: TAIR
  • response to salt stress Source: TAIR
  • response to wounding Source: TAIR

Keywordsi

Molecular functionGlycosidase, Hydrolase
Biological processCarbohydrate metabolism, Chitin degradation, Polysaccharide degradation

Enzyme and pathway databases

BioCyciARA:AT5G24090-MONOMER

Protein family/group databases

CAZyiGH18 Glycoside Hydrolase Family 18

Names & Taxonomyi

Protein namesi
Recommended name:
Acidic endochitinase (EC:3.2.1.14)
Gene namesi
Name:CHIB1
Ordered Locus Names:At5g24090
ORF Names:MZF18.2
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

AraportiAT5G24090
TAIRilocus:2178702 AT5G24090

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 30Add BLAST30
ChainiPRO_000001191331 – 302Acidic endochitinaseAdd BLAST272

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi49 ↔ 96By similarity
Disulfide bondi79 ↔ 86By similarity
Disulfide bondi188 ↔ 217By similarity

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiP19172
PRIDEiP19172

Expressioni

Inductioni

Expression of the acidic chitinase gene was not detected in normal, untreated plants nor in plants treated with ethylene or salicylic acid.

Gene expression databases

ExpressionAtlasiP19172 baseline and differential
GenevisibleiP19172 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT5G24090.1

Structurei

3D structure databases

ProteinModelPortaliP19172
SMRiP19172
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiKOG4701 Eukaryota
ENOG4111GPA LUCA
InParanoidiP19172
KOiK01183
OMAiQTPEMNL
OrthoDBiEOG09360IVR
PhylomeDBiP19172

Family and domain databases

InterProiView protein in InterPro
IPR001223 Glyco_hydro18_cat
IPR001579 Glyco_hydro_18_chit_AS
IPR017853 Glycoside_hydrolase_SF
PfamiView protein in Pfam
PF00704 Glyco_hydro_18, 1 hit
SUPFAMiSSF51445 SSF51445, 1 hit
PROSITEiView protein in PROSITE
PS01095 CHITINASE_18, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P19172-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTNMTLRKHV IYFLFFISCS LSKPSDASRG GIAIYWGQNG NEGNLSATCA
60 70 80 90 100
TGRYAYVNVA FLVKFGNGQT PELNLAGHCN PAANTCTHFG SQVKDCQSRG
110 120 130 140 150
IKVMLSLGGG IGNYSIGSRE DAKVIADYLW NNFLGGKSSS RPLGDAVLDG
160 170 180 190 200
IDFNIELGSP QHWDDLARTL SKFSHRGRKI YLTGAPQCPF PDRLMGSALN
210 220 230 240 250
TKRFDYVWIQ FYNNPPCSYS SGNTQNLFDS WNKWTTSIAA QKFFLGLPAA
260 270 280 290 300
PEAAGSGYIP PDVLTSQILP TLKKSRKYGG VMLWSKFWDD KNGYSSSILA

SV
Length:302
Mass (Da):33,097
Last modified:January 10, 2003 - v2
Checksum:i522AEB092E6EDCA8
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti255G → D in AAA32768 (PubMed:16667600).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural varianti22S → T in strain: cv. Ci-0. 1
Natural varianti42E → A in strain: cv. Es-0. 1
Natural varianti69Q → R in strain: cv. Ci-0. 1
Natural varianti120E → K in strain: cv. Ci-0. 1
Natural varianti125I → V in strain: cv. Ci-0. 1
Natural varianti169T → S in strain: cv. Ci-0, cv. Ita-0 and cv. Pog-0. 1
Natural varianti173F → Y in strain: cv. Ci-0. 1
Natural varianti174S → T in strain: cv. Yo-0. 1
Natural varianti180I → V in strain: cv. Ita-0 and cv. Pog-0. 1
Natural varianti217C → W in strain: cv. Mt-0. 1
Natural varianti220S → T in strain: cv. Ita-0 and cv. Pog-0. 1
Natural varianti239A → T in strain: cv. Chi-0. 1
Natural varianti243F → I in strain: cv. Ita-0. 1
Natural varianti243F → L in strain: cv. Pog-0. 1
Natural varianti257G → V in strain: cv. Yo-0. 1
Natural varianti274K → N in strain: cv. Ci-0. 1
Natural varianti299L → S in strain: cv. Bla-10. 1
Natural varianti299L → V in strain: cv. Bs-1. 1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M34107 Genomic DNA Translation: AAA32768.1
AB006055 Genomic DNA Translation: BAA21860.1
AB006056 Genomic DNA Translation: BAA21861.1
AB006057 Genomic DNA Translation: BAA21862.1
AB006058 Genomic DNA Translation: BAA21863.1
AB006059 Genomic DNA Translation: BAA21864.1
AB006060 Genomic DNA Translation: BAA21865.1
AB006061 Genomic DNA Translation: BAA21866.1
AB006062 Genomic DNA Translation: BAA21867.1
AB006063 Genomic DNA Translation: BAA21868.1
AB006064 Genomic DNA Translation: BAA21869.1
AB006065 Genomic DNA Translation: BAA21870.1
AB006066 Genomic DNA Translation: BAA21871.1
AB006067 Genomic DNA Translation: BAA21872.1
AB006068 Genomic DNA Translation: BAA21873.1
AB006069 Genomic DNA Translation: BAA21874.1
AB009056 Genomic DNA Translation: BAB08732.1
CP002688 Genomic DNA Translation: AED93255.1
BT020526 mRNA Translation: AAW49295.1
BT021931 mRNA Translation: AAX49380.1
PIRiA45511
RefSeqiNP_197797.1, NM_122314.3
UniGeneiAt.43218

Genome annotation databases

EnsemblPlantsiAT5G24090.1; AT5G24090.1; AT5G24090
GeneIDi832474
GrameneiAT5G24090.1; AT5G24090.1; AT5G24090
KEGGiath:AT5G24090

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiCHIA_ARATH
AccessioniPrimary (citable) accession number: P19172
Secondary accession number(s): O22065
, O22066, O22067, O22068, O22069, O22070, O22071, O22072, O22073, O24614, Q5HYZ8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1990
Last sequence update: January 10, 2003
Last modified: April 25, 2018
This is version 147 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

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