Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Beta-(1-->2)glucan export ATP-binding/permease protein NdvA

Gene

ndvA

Organism
Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in beta-(1-->2)glucan export which is required for nodulation of legume roots. May be involved in other classes of oligosaccharides export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (Probable).1 Publication

Catalytic activityi

ATP + H2O + beta-glucan(In) = ADP + phosphate + beta-glucan(Out).UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi368 – 375ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase
Biological processSugar transport, Transport
LigandATP-binding, Nucleotide-binding

Protein family/group databases

TCDBi3.A.1.108.1 the atp-binding cassette (abc) superfamily

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-(1-->2)glucan export ATP-binding/permease protein NdvAUniRule annotation (EC:3.6.3.42UniRule annotation)
Gene namesi
Name:ndvAUniRule annotation
Ordered Locus Names:R03283
ORF Names:SMc03900
OrganismiRhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
Taxonomic identifieri266834 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium
Proteomesi
  • UP000001976 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei22 – 42HelicalUniRule annotationAdd BLAST21
Transmembranei55 – 75HelicalUniRule annotationAdd BLAST21
Transmembranei136 – 156HelicalUniRule annotationAdd BLAST21
Transmembranei158 – 178HelicalUniRule annotationAdd BLAST21
Transmembranei245 – 265HelicalUniRule annotationAdd BLAST21
Transmembranei269 – 289HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000926171 – 585Beta-(1-->2)glucan export ATP-binding/permease protein NdvAAdd BLAST585

Proteomic databases

PRIDEiP18767

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi266834.SMc03900

Structurei

3D structure databases

ProteinModelPortaliP18767
SMRiP18767
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini21 – 301ABC transmembrane type-1UniRule annotationAdd BLAST281
Domaini335 – 569ABC transporterUniRule annotationAdd BLAST235

Domaini

In NdvA the ATP-binding domain (NBD) and the transmembrane domain (TMD) are fused.

Sequence similaritiesi

Belongs to the ABC transporter superfamily. Beta-(1-->2)glucan exporter (TC 3.A.1.108.1) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105BZ1 Bacteria
COG1132 LUCA
KOiK06147

Family and domain databases

Gene3Di1.20.1560.10, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR017902 ABC_bGlucan_ATPase
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR005896 NdvA
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00664 ABC_membrane, 1 hit
PF00005 ABC_tran, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
SSF90123 SSF90123, 1 hit
TIGRFAMsiTIGR01192 chvA, 1 hit
PROSITEiView protein in PROSITE
PS50929 ABC_TM1F, 1 hit
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 1 hit
PS51317 NDVA, 1 hit

Sequencei

Sequence statusi: Complete.

P18767-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLFQVYARA LQYLAVHKFR VGAIVIANIV LAAITIAEPI LFGRIIDAIS
60 70 80 90 100
SQKDVAPMLL LWAGFGVFNT IAFVLVSREA DRLAHGRRAS LLTEAFGRIV
110 120 130 140 150
SMPLSWHSQR GTSNALHTLL RACETLFGLW LEFMRQHLAT AVALMLLIPT
160 170 180 190 200
AFAMDVRLSL ILVVLGAAYV MISKVVMSRT KEGQAAVEGH YHTVFSHVSD
210 220 230 240 250
SISNVSVVHS YNRIEAETRE LKKFTQRLLS AQYPVLDWWA LASGLNRIAS
260 270 280 290 300
TISMMAILVI GTVLVQRGEL GVGEVIAFIG FANLLIGRLD QMKAFATQIF
310 320 330 340 350
EARAKLEDFF QLEDSVQDRE EPADAGELKG VVGEVEFRDI SFDFANSAQG
360 370 380 390 400
VRNVSFKAKA GQTIAIVGPT GAGKTTLVNL LQRVHEPKHG QILIDGVDIA
410 420 430 440 450
TVTRKSLRRS IATVFQDAGL MNRSIGENIR LGREDASLDE VMAAAEAAAA
460 470 480 490 500
SDFIEDRLNG YDTVVGERGN RLSGGERQRV AIARAILKNA PILVLDEATS
510 520 530 540 550
ALDVETEARV KDAIDALRKD RTTFIIAHRL STVREADLVI FMDQGRVVEM
560 570 580
GGFHELSQSN GRFAALLRAS GILTDEDVRK SLTAA
Length:585
Mass (Da):63,954
Last modified:June 12, 2007 - v2
Checksum:i2B7F115C2A7333F8
GO

Sequence cautioni

The sequence AAA26304 differs from that shown. Reason: Erroneous initiation.Curated
The sequence CAC47862 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M20726 Genomic DNA Translation: AAA26304.1 Different initiation.
AL591688 Genomic DNA Translation: CAC47862.1 Different initiation.
PIRiA31094 VXZRNA
RefSeqiNP_387389.1, NC_003047.1
WP_010970541.1, NC_003047.1

Genome annotation databases

EnsemblBacteriaiCAC47862; CAC47862; SMc03900
GeneIDi1234977
KEGGisme:SMc03900
PATRICifig|266834.11.peg.4842

Similar proteinsi

Entry informationi

Entry nameiNDVA_RHIME
AccessioniPrimary (citable) accession number: P18767
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1990
Last sequence update: June 12, 2007
Last modified: October 25, 2017
This is version 126 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health