RPL7

Functionⁱ

Component of the large ribosomal subunit (PubMed:12962325). Binds to G-rich structures in 28S rRNA and in mRNAs. Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs.1 Publication

GO - Molecular functionⁱ

DNA binding
Source: MGI
Inferred from direct assayⁱ
- 8441630
mRNA binding
Source: MGI
Inferred from direct assayⁱ
- 8441630
protein homodimerization activity
Source: MGI
Inferred from physical interactionⁱ
- 8441630
RNA binding
Source: UniProtKB
Inferred from high throughput direct assayⁱ
- 22658674
- 22681889
structural constituent of ribosome Source: GO_Central

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

cytoplasmic translation Source: GO_Central
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Source: GO_Central
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay Source: Reactome
ribosomal large subunit biogenesis
Source: UniProtKB
Inferred from mutant phenotypeⁱ
- 18697920
rRNA processing
Source: UniProtKB
Inferred from mutant phenotypeⁱ
- 18697920
SRP-dependent cotranslational protein targeting to membrane Source: Reactome
translation
Source: ProtInc
Traceable author statementⁱ
- 8360149
translational initiation Source: Reactome

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Ribonucleoprotein, Ribosomal protein, RNA-binding

Molecular function

Ribonucleoprotein, Ribosomal protein, RNA-binding

Enzyme and pathway databases

Reactomeⁱ	R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156902 Peptide chain elongation R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane R-HSA-192823 Viral mRNA Translation R-HSA-2408557 Selenocysteine synthesis R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-72689 Formation of a pool of free 40S subunits R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72764 Eukaryotic Translation Termination R-HSA-9010553 Regulation of expression of SLITs and ROBOs R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Reactomeⁱ

R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-HSA-156902 Peptide chain elongation
R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-HSA-192823 Viral mRNA Translation
R-HSA-2408557 Selenocysteine synthesis
R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-HSA-72689 Formation of a pool of free 40S subunits
R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-HSA-72764 Eukaryotic Translation Termination
R-HSA-9010553 Regulation of expression of SLITs and ROBOs
R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: 60S ribosomal protein L7 Alternative name(s): Large ribosomal subunit protein uL301 Publication
Gene namesⁱ	Name:RPL7
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 8

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000147604.13
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:10363 RPL7
MIMⁱ	604166 gene
neXtProtⁱ	NX_P18124

Subcellular locationⁱ

GO - Cellular component

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	6129
Open Targets More...OpenTargetsⁱ	ENSG00000147604
PharmGKBⁱ	PA34759

Polymorphism and mutation databases

BioMutaⁱ	RPL7
DMDMⁱ	133021

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000104633	1 – 248	60S ribosomal protein L7Add BLAST		248

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Modified residueⁱ	1	N-acetylmethionineCombined sources2 Publications	1
Modified residueⁱ	17	PhosphothreonineCombined sources	1
Modified residueⁱ	124	N6-acetyllysineCombined sources	1
Modified residueⁱ	127	N6-succinyllysineBy similarity	1
Modified residueⁱ	139	PhosphotyrosineCombined sources	1

Keywords - PTMⁱ

Acetylation, Phosphoprotein

Proteomic databases

EPDⁱ	P18124
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	P18124
PaxDbⁱ	P18124
PeptideAtlas More...PeptideAtlasⁱ	P18124
PRIDEⁱ	P18124
ProteomicsDBⁱ	53549
TopDownProteomicsⁱ	P18124

2D gel databases

SWISS-2DPAGEⁱ	P18124

SWISS-2DPAGEⁱ

P18124

PTM databases

iPTMnetⁱ	P18124
PhosphoSitePlusⁱ	P18124
SwissPalmⁱ	P18124

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000147604
CleanExⁱ	HS_RPL7
ExpressionAtlasⁱ	P18124 baseline and differential
Genevisibleⁱ	P18124 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA058373

HPAⁱ

HPA058373

Interactionⁱ

Subunit structureⁱ

Component of the large ribosomal subunit (Probable). Homodimer. Interacts with DHX33 (PubMed:26100019).1 Publication1 Publication

Binary interactionsⁱ

With	Entry	#Exp.	IntAct	Notes
IPO5	O00410	4	EBI-350806,EBI-356424
NEDD8	Q15843	2	EBI-350806,EBI-716247

Show more details

GO - Molecular functionⁱ

protein homodimerization activity
Source: MGI
Inferred from physical interactionⁱ
- 8441630

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

BioGridⁱ	112049, 230 interactors
CORUMⁱ	P18124
IntActⁱ	P18124, 55 interactors
Molecular INTeraction database More...MINTⁱ	P18124
STRINGⁱ	9606.ENSP00000339795

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P18124
SMRⁱ	P18124
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Repeatⁱ	7 – 18	1Add BLAST	12
Repeatⁱ	19 – 30	2Add BLAST	12
Repeatⁱ	31 – 42	3Add BLAST	12
Repeatⁱ	43 – 54	4Add BLAST	12

Region

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Regionⁱ	7 – 54	4 X 12 AA tandem repeatsAdd BLAST		48

Sequence similaritiesⁱ

Belongs to the universal ribosomal protein uL30 family.Curated

Keywords - Domainⁱ

Repeat

Phylogenomic databases

eggNOGⁱ	KOG3184 Eukaryota COG1841 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000006213
HOGENOMⁱ	HOG000170917
HOVERGENⁱ	HBG003280
InParanoidⁱ	P18124
KEGG Orthology (KO) More...KOⁱ	K02937
OMAⁱ	PTGGWRT
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0IHS
PhylomeDBⁱ	P18124
TreeFamⁱ	TF300740

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd01657 Ribosomal_L7_archeal_euk, 1 hit
Gene3Dⁱ	1.10.15.30, 1 hit 3.30.1390.20, 2 hits
InterProⁱ	View protein in InterPro IPR036919 L30_ferredoxin-like_sf IPR023106 Ribosomal_L30_central_dom_arc IPR018038 Ribosomal_L30_CS IPR016082 Ribosomal_L30_ferredoxin-like IPR012988 Ribosomal_L30_N IPR005998 Ribosomal_L7_euk IPR035808 Ribosomal_L7_euk_arc
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00327 Ribosomal_L30, 1 hit PF08079 Ribosomal_L30_N, 1 hit
SUPFAMⁱ	SSF55129 SSF55129, 1 hit
TIGRFAMsⁱ	TIGR01310 uL30_euk, 1 hit
PROSITEⁱ	View protein in PROSITE PS00634 RIBOSOMAL_L30, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

P18124-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MEGVEEKKKE VPAVPETLKK KRRNFAELKI KRLRKKFAQK MLRKARRKLI 
        60         70         80         90        100
YEKAKHYHKE YRQMYRTEIR MARMARKAGN FYVPAEPKLA FVIRIRGING 
       110        120        130        140        150
VSPKVRKVLQ LLRLRQIFNG TFVKLNKASI NMLRIVEPYI AWGYPNLKSV 
       160        170        180        190        200
NELIYKRGYG KINKKRIALT DNALIARSLG KYGIICMEDL IHEIYTVGKR 
       210        220        230        240 
FKEANNFLWP FKLSSPRGGM KKKTTHFVEG GDAGNREDQI NRLIRRMN

Length:248

Mass (Da):29,226

Last modified:November 1, 1990 - v1

Checksum:ⁱ070EB4C904E6795A

GO

Sequence cautionⁱ

The sequence CAA41026 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature key	Position(s)	DescriptionActions	Length
Sequence conflictⁱ	48	K → E in CAG33054 (Ref. 4) Curated	1
Sequence conflictⁱ	157	R → L in CAA41026 (PubMed:8441630).Curated	1
Sequence conflictⁱ	157	R → L in CAA41027 (PubMed:8441630).Curated	1
Sequence conflictⁱ	160	G → A in CAA41026 (PubMed:8441630).Curated	1
Sequence conflictⁱ	166	R → Q in CAA41026 (PubMed:8441630).Curated	1
Sequence conflictⁱ	173	A → S in AAA03081 (PubMed:8360149).Curated	1
Sequence conflictⁱ	192	H → R in CAG33054 (Ref. 4) Curated	1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	X57958 mRNA Translation: CAA41026.1 Different initiation. X57959 mRNA Translation: CAA41027.1 L16558 mRNA Translation: AAA03081.1 X52967 mRNA Translation: CAA37139.1 CR456773 mRNA Translation: CAG33054.1 AK291119 mRNA Translation: BAF83808.1 AK313365 mRNA Translation: BAG36165.1 BC006095 mRNA Translation: AAH06095.1 BC008850 mRNA Translation: AAH08850.1 BC009599 mRNA Translation: AAH09599.1 BC071671 mRNA Translation: AAH71671.1 BC071894 mRNA Translation: AAH71894.1 BC071895 mRNA Translation: AAH71895.1 BC087837 mRNA Translation: AAH87837.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS6212.1
PIRⁱ	S11709 R5HU7
NCBI Reference Sequences More...RefSeqⁱ	NP_000962.2, NM_000971.3
UniGeneⁱ	Hs.421257 Hs.571841

Genome annotation databases

Ensemblⁱ	ENST00000352983; ENSP00000339795; ENSG00000147604
GeneIDⁱ	6129
KEGGⁱ	hsa:6129
UCSC genome browser More...UCSCⁱ	uc003xzg.4 human

Protein	Similar proteins		Species	Score	Length
P18124	Ribosomal protein L7		PANTR		248
Ribosomal protein L7		PANPA		248
Uncharacterized protein		GORGO		248
Ribosomal protein L7, isoform CRA_a		HUMAN		259

Protein	Similar proteins		Species	Score	Length
P18124	Ribosomal protein L7		PANTR		248
Ribosomal protein L7		PANPA		248
Uncharacterized protein		GORGO		248
Ribosomal protein L7, isoform CRA_a		HUMAN		259
UPI0004F2012B		PAPAN		263
+38

Protein	Similar proteins		Species	Score	Length
P18124	Ribosomal protein L7		PANTR		248
Ribosomal protein L7		PANPA		248
Uncharacterized protein		GORGO		248
Ribosomal protein L7, isoform CRA_a		HUMAN		259
UPI0004F2012B		PAPAN		263
+223

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	X57958 mRNA Translation: CAA41026.1 Different initiation. X57959 mRNA Translation: CAA41027.1 L16558 mRNA Translation: AAA03081.1 X52967 mRNA Translation: CAA37139.1 CR456773 mRNA Translation: CAG33054.1 AK291119 mRNA Translation: BAF83808.1 AK313365 mRNA Translation: BAG36165.1 BC006095 mRNA Translation: AAH06095.1 BC008850 mRNA Translation: AAH08850.1 BC009599 mRNA Translation: AAH09599.1 BC071671 mRNA Translation: AAH71671.1 BC071894 mRNA Translation: AAH71894.1 BC071895 mRNA Translation: AAH71895.1 BC087837 mRNA Translation: AAH87837.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS6212.1
PIRⁱ	S11709 R5HU7
NCBI Reference Sequences More...RefSeqⁱ	NP_000962.2, NM_000971.3
UniGeneⁱ	Hs.421257 Hs.571841

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	4UG0	electron microscopy	-	LF	1-248	[»]
	4V6X	electron microscopy	5.00	CF	1-248	[»]
	5AJ0	electron microscopy	3.50	AF	1-248	[»]
	5LKS	electron microscopy	3.60	LF	1-248	[»]
	5T2C	electron microscopy	3.60	m	1-248	[»]
	6EK0	electron microscopy	2.90	LF	1-248	[»]
ProteinModelPortalⁱ	P18124
SMRⁱ	P18124
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	112049, 230 interactors
CORUMⁱ	P18124
IntActⁱ	P18124, 55 interactors
Molecular INTeraction database More...MINTⁱ	P18124
STRINGⁱ	9606.ENSP00000339795

PTM databases

iPTMnetⁱ	P18124
PhosphoSitePlusⁱ	P18124
SwissPalmⁱ	P18124

Polymorphism and mutation databases

BioMutaⁱ	RPL7
DMDMⁱ	133021

2D gel databases

SWISS-2DPAGEⁱ	P18124

SWISS-2DPAGEⁱ

P18124

Proteomic databases

EPDⁱ	P18124
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	P18124
PaxDbⁱ	P18124
PeptideAtlas More...PeptideAtlasⁱ	P18124
PRIDEⁱ	P18124
ProteomicsDBⁱ	53549
TopDownProteomicsⁱ	P18124

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	6129
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000352983; ENSP00000339795; ENSG00000147604
GeneIDⁱ	6129
KEGGⁱ	hsa:6129
UCSC genome browser More...UCSCⁱ	uc003xzg.4 human

Organism-specific databases

CTDⁱ	6129
DisGeNET More...DisGeNETⁱ	6129
EuPathDBⁱ	HostDB:ENSG00000147604.13
GeneCardsⁱ	RPL7
H-InvDBⁱ	HIX0058339
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:10363 RPL7
Human Protein Atlas More...HPAⁱ	HPA058373
MIMⁱ	604166 gene
neXtProtⁱ	NX_P18124
Open Targets More...OpenTargetsⁱ	ENSG00000147604
PharmGKBⁱ	PA34759
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG3184 Eukaryota COG1841 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000006213
HOGENOMⁱ	HOG000170917
HOVERGENⁱ	HBG003280
InParanoidⁱ	P18124
KEGG Orthology (KO) More...KOⁱ	K02937
OMAⁱ	PTGGWRT
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0IHS
PhylomeDBⁱ	P18124
TreeFamⁱ	TF300740

Enzyme and pathway databases

Reactomeⁱ	R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156902 Peptide chain elongation R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane R-HSA-192823 Viral mRNA Translation R-HSA-2408557 Selenocysteine synthesis R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-72689 Formation of a pool of free 40S subunits R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72764 Eukaryotic Translation Termination R-HSA-9010553 Regulation of expression of SLITs and ROBOs R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Reactomeⁱ

R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-HSA-156902 Peptide chain elongation
R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-HSA-192823 Viral mRNA Translation
R-HSA-2408557 Selenocysteine synthesis
R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-HSA-72689 Formation of a pool of free 40S subunits
R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-HSA-72764 Eukaryotic Translation Termination
R-HSA-9010553 Regulation of expression of SLITs and ROBOs
R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Miscellaneous databases

ChiTaRSⁱ	RPL7 human
GeneWikiⁱ	RPL7
GenomeRNAiⁱ	6129
Protein Ontology More...PROⁱ	PR:P18124
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000147604
CleanExⁱ	HS_RPL7
ExpressionAtlasⁱ	P18124 baseline and differential
Genevisibleⁱ	P18124 HS

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd01657 Ribosomal_L7_archeal_euk, 1 hit
Gene3Dⁱ	1.10.15.30, 1 hit 3.30.1390.20, 2 hits
InterProⁱ	View protein in InterPro IPR036919 L30_ferredoxin-like_sf IPR023106 Ribosomal_L30_central_dom_arc IPR018038 Ribosomal_L30_CS IPR016082 Ribosomal_L30_ferredoxin-like IPR012988 Ribosomal_L30_N IPR005998 Ribosomal_L7_euk IPR035808 Ribosomal_L7_euk_arc
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00327 Ribosomal_L30, 1 hit PF08079 Ribosomal_L30_N, 1 hit
SUPFAMⁱ	SSF55129 SSF55129, 1 hit
TIGRFAMsⁱ	TIGR01310 uL30_euk, 1 hit
PROSITEⁱ	View protein in PROSITE PS00634 RIBOSOMAL_L30, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	RL7_HUMAN
Accessionⁱ	P18124Primary (citable) accession number: P18124 Secondary accession number(s): A8K504 , Q15289, Q3KQU0, Q5I0X1, Q6IBM9
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	November 1, 1990
	Last sequence update:	November 1, 1990
	Last modified:	July 18, 2018
	This is version 197 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

Human chromosome 8
Human chromosome 8: entries, gene names and cross-references to MIM
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
PDB cross-references
Index of Protein Data Bank (PDB) cross-references
Ribosomal proteins
Ribosomal proteins families and list of entries
SIMILARITY comments
Index of protein domains and families

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Supporting data

UniProtKB - P18124 (RL7_HUMAN)

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60S ribosomal protein L7

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Cytosol

Nucleus

Other locations

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Proteomic databases

2D gel databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Region

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

2D gel databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequence cautionⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ