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Protein

60S ribosomal protein L7

Gene

RPL7

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Component of the large ribosomal subunit (PubMed:12962325). Binds to G-rich structures in 28S rRNA and in mRNAs. Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • DNA binding Source: MGI
  • mRNA binding Source: MGI
  • protein homodimerization activity Source: MGI
  • RNA binding Source: UniProtKB
  • structural constituent of ribosome Source: GO_Central

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-HSA-156902 Peptide chain elongation
R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-HSA-192823 Viral mRNA Translation
R-HSA-2408557 Selenocysteine synthesis
R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-HSA-72689 Formation of a pool of free 40S subunits
R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-HSA-72764 Eukaryotic Translation Termination
R-HSA-9010553 Regulation of expression of SLITs and ROBOs
R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
60S ribosomal protein L7
Alternative name(s):
Large ribosomal subunit protein uL301 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RPL7
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000147604.13

Human Gene Nomenclature Database

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HGNCi
HGNC:10363 RPL7

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
604166 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P18124

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
6129

Open Targets

More...
OpenTargetsi
ENSG00000147604

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA34759

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
RPL7

Domain mapping of disease mutations (DMDM)

More...
DMDMi
133021

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001046331 – 24860S ribosomal protein L7Add BLAST248

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionineCombined sources2 Publications1
Modified residuei17PhosphothreonineCombined sources1
Modified residuei124N6-acetyllysineCombined sources1
Modified residuei127N6-succinyllysineBy similarity1
Modified residuei139PhosphotyrosineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P18124

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P18124

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P18124

PeptideAtlas

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PeptideAtlasi
P18124

PRoteomics IDEntifications database

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PRIDEi
P18124

ProteomicsDB human proteome resource

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ProteomicsDBi
53549

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
P18124

2D gel databases

Two-dimensional polyacrylamide gel electrophoresis database from the Geneva University Hospital

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SWISS-2DPAGEi
P18124

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P18124

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P18124

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
P18124

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSG00000147604 Expressed in 180 organ(s), highest expression level in colon

CleanEx database of gene expression profiles

More...
CleanExi
HS_RPL7

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P18124 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P18124 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA058373

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the large ribosomal subunit (Probable). Homodimer. Interacts with DHX33 (PubMed:26100019).1 Publication1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
112049, 232 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
P18124

Protein interaction database and analysis system

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IntActi
P18124, 51 interactors

Molecular INTeraction database

More...
MINTi
P18124

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000339795

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
P18124

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
P18124

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati7 – 181Add BLAST12
Repeati19 – 302Add BLAST12
Repeati31 – 423Add BLAST12
Repeati43 – 544Add BLAST12

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni7 – 544 X 12 AA tandem repeatsAdd BLAST48

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3184 Eukaryota
COG1841 LUCA

Ensembl GeneTree

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GeneTreei
ENSGT00940000153091

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000170917

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG003280

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
P18124

KEGG Orthology (KO)

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KOi
K02937

Identification of Orthologs from Complete Genome Data

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OMAi
PTGGWRT

Database of Orthologous Groups

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OrthoDBi
EOG091G0IHS

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P18124

TreeFam database of animal gene trees

More...
TreeFami
TF300740

Family and domain databases

Conserved Domains Database

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CDDi
cd01657 Ribosomal_L7_archeal_euk, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

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Gene3Di
1.10.15.30, 1 hit
3.30.1390.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036919 L30_ferredoxin-like_sf
IPR023106 Ribosomal_L30_central_dom_arc
IPR018038 Ribosomal_L30_CS
IPR016082 Ribosomal_L30_ferredoxin-like
IPR012988 Ribosomal_L30_N
IPR039699 Ribosomal_L7/L30
IPR005998 Ribosomal_L7_euk
IPR035808 Ribosomal_L7_euk_arc

The PANTHER Classification System

More...
PANTHERi
PTHR11524 PTHR11524, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00327 Ribosomal_L30, 1 hit
PF08079 Ribosomal_L30_N, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF55129 SSF55129, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01310 uL30_euk, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00634 RIBOSOMAL_L30, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

P18124-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEGVEEKKKE VPAVPETLKK KRRNFAELKI KRLRKKFAQK MLRKARRKLI
60 70 80 90 100
YEKAKHYHKE YRQMYRTEIR MARMARKAGN FYVPAEPKLA FVIRIRGING
110 120 130 140 150
VSPKVRKVLQ LLRLRQIFNG TFVKLNKASI NMLRIVEPYI AWGYPNLKSV
160 170 180 190 200
NELIYKRGYG KINKKRIALT DNALIARSLG KYGIICMEDL IHEIYTVGKR
210 220 230 240
FKEANNFLWP FKLSSPRGGM KKKTTHFVEG GDAGNREDQI NRLIRRMN
Length:248
Mass (Da):29,226
Last modified:November 1, 1990 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i070EB4C904E6795A
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A8MUD9A8MUD9_HUMAN
60S ribosomal protein L7
RPL7
208Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JIJ5C9JIJ5_HUMAN
60S ribosomal protein L7
RPL7
99Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JZ88C9JZ88_HUMAN
60S ribosomal protein L7
RPL7
88Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence CAA41026 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti48K → E in CAG33054 (Ref. 4) Curated1
Sequence conflicti157R → L in CAA41026 (PubMed:8441630).Curated1
Sequence conflicti157R → L in CAA41027 (PubMed:8441630).Curated1
Sequence conflicti160G → A in CAA41026 (PubMed:8441630).Curated1
Sequence conflicti166R → Q in CAA41026 (PubMed:8441630).Curated1
Sequence conflicti173A → S in AAA03081 (PubMed:8360149).Curated1
Sequence conflicti192H → R in CAG33054 (Ref. 4) Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X57958 mRNA Translation: CAA41026.1 Different initiation.
X57959 mRNA Translation: CAA41027.1
L16558 mRNA Translation: AAA03081.1
X52967 mRNA Translation: CAA37139.1
CR456773 mRNA Translation: CAG33054.1
AK291119 mRNA Translation: BAF83808.1
AK313365 mRNA Translation: BAG36165.1
BC006095 mRNA Translation: AAH06095.1
BC008850 mRNA Translation: AAH08850.1
BC009599 mRNA Translation: AAH09599.1
BC071671 mRNA Translation: AAH71671.1
BC071894 mRNA Translation: AAH71894.1
BC071895 mRNA Translation: AAH71895.1
BC087837 mRNA Translation: AAH87837.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS6212.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S11709 R5HU7

NCBI Reference Sequences

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RefSeqi
NP_000962.2, NM_000971.3

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.421257
Hs.571841

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000352983; ENSP00000339795; ENSG00000147604

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
6129

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:6129

UCSC genome browser

More...
UCSCi
uc003xzg.4 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X57958 mRNA Translation: CAA41026.1 Different initiation.
X57959 mRNA Translation: CAA41027.1
L16558 mRNA Translation: AAA03081.1
X52967 mRNA Translation: CAA37139.1
CR456773 mRNA Translation: CAG33054.1
AK291119 mRNA Translation: BAF83808.1
AK313365 mRNA Translation: BAG36165.1
BC006095 mRNA Translation: AAH06095.1
BC008850 mRNA Translation: AAH08850.1
BC009599 mRNA Translation: AAH09599.1
BC071671 mRNA Translation: AAH71671.1
BC071894 mRNA Translation: AAH71894.1
BC071895 mRNA Translation: AAH71895.1
BC087837 mRNA Translation: AAH87837.1
CCDSiCCDS6212.1
PIRiS11709 R5HU7
RefSeqiNP_000962.2, NM_000971.3
UniGeneiHs.421257
Hs.571841

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

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PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4UG0electron microscopy-LF1-248[»]
4V6Xelectron microscopy5.00CF1-248[»]
5AJ0electron microscopy3.50AF1-248[»]
5LKSelectron microscopy3.60LF1-248[»]
5T2Celectron microscopy3.60m1-248[»]
6EK0electron microscopy2.90LF1-248[»]
ProteinModelPortaliP18124
SMRiP18124
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi112049, 232 interactors
CORUMiP18124
IntActiP18124, 51 interactors
MINTiP18124
STRINGi9606.ENSP00000339795

PTM databases

iPTMnetiP18124
PhosphoSitePlusiP18124
SwissPalmiP18124

Polymorphism and mutation databases

BioMutaiRPL7
DMDMi133021

2D gel databases

SWISS-2DPAGEiP18124

Proteomic databases

EPDiP18124
MaxQBiP18124
PaxDbiP18124
PeptideAtlasiP18124
PRIDEiP18124
ProteomicsDBi53549
TopDownProteomicsiP18124

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
6129
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000352983; ENSP00000339795; ENSG00000147604
GeneIDi6129
KEGGihsa:6129
UCSCiuc003xzg.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
6129
DisGeNETi6129
EuPathDBiHostDB:ENSG00000147604.13

GeneCards: human genes, protein and diseases

More...
GeneCardsi
RPL7

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0058339
HGNCiHGNC:10363 RPL7
HPAiHPA058373
MIMi604166 gene
neXtProtiNX_P18124
OpenTargetsiENSG00000147604
PharmGKBiPA34759

GenAtlas: human gene database

More...
GenAtlasi
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Phylogenomic databases

eggNOGiKOG3184 Eukaryota
COG1841 LUCA
GeneTreeiENSGT00940000153091
HOGENOMiHOG000170917
HOVERGENiHBG003280
InParanoidiP18124
KOiK02937
OMAiPTGGWRT
OrthoDBiEOG091G0IHS
PhylomeDBiP18124
TreeFamiTF300740

Enzyme and pathway databases

ReactomeiR-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-HSA-156902 Peptide chain elongation
R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-HSA-192823 Viral mRNA Translation
R-HSA-2408557 Selenocysteine synthesis
R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-HSA-72689 Formation of a pool of free 40S subunits
R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-HSA-72764 Eukaryotic Translation Termination
R-HSA-9010553 Regulation of expression of SLITs and ROBOs
R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
RPL7 human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
RPL7

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
6129

Protein Ontology

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PROi
PR:P18124

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000147604 Expressed in 180 organ(s), highest expression level in colon
CleanExiHS_RPL7
ExpressionAtlasiP18124 baseline and differential
GenevisibleiP18124 HS

Family and domain databases

CDDicd01657 Ribosomal_L7_archeal_euk, 1 hit
Gene3Di1.10.15.30, 1 hit
3.30.1390.20, 1 hit
InterProiView protein in InterPro
IPR036919 L30_ferredoxin-like_sf
IPR023106 Ribosomal_L30_central_dom_arc
IPR018038 Ribosomal_L30_CS
IPR016082 Ribosomal_L30_ferredoxin-like
IPR012988 Ribosomal_L30_N
IPR039699 Ribosomal_L7/L30
IPR005998 Ribosomal_L7_euk
IPR035808 Ribosomal_L7_euk_arc
PANTHERiPTHR11524 PTHR11524, 1 hit
PfamiView protein in Pfam
PF00327 Ribosomal_L30, 1 hit
PF08079 Ribosomal_L30_N, 1 hit
SUPFAMiSSF55129 SSF55129, 1 hit
TIGRFAMsiTIGR01310 uL30_euk, 1 hit
PROSITEiView protein in PROSITE
PS00634 RIBOSOMAL_L30, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRL7_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P18124
Secondary accession number(s): A8K504
, Q15289, Q3KQU0, Q5I0X1, Q6IBM9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1990
Last sequence update: November 1, 1990
Last modified: December 5, 2018
This is version 201 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome 8
    Human chromosome 8: entries, gene names and cross-references to MIM
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families
  4. Ribosomal proteins
    Ribosomal proteins families and list of entries
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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