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Entry version 130 (29 Sep 2021)
Sequence version 2 (16 Jun 2009)
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Protein

DNA repair protein RecN

Gene

recN

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in recombinational repair of damaged DNA. Seems to be the first protein recruited to repair centers, foci that are the site of double-strand DNA break(s), followed by RecO and then RecF.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi29 – 36ATPSequence analysis8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processDNA damage, DNA repair
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
BSUB:BSU24240-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
DNA repair protein RecN
Alternative name(s):
Recombination protein N
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:recN
Ordered Locus Names:BSU24240
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBacillus subtilis (strain 168)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri224308 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001570 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001880141 – 576DNA repair protein RecNAdd BLAST576

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
P17894

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P17894

PRoteomics IDEntifications database

More...
PRIDEi
P17894

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Forms multimers, possibly octamers; these become larger following DNA damage. Recruited to foci following DNA damage; probably interacts with RecF and RecO.

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
224308.BSU24240

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P17894

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the RecN family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
COG0497, Bacteria

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P17894

Identification of Orthologs from Complete Genome Data

More...
OMAi
QVICVTH

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P17894

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.50.300, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR004604, DNA_recomb/repair_RecN
IPR027417, P-loop_NTPase
IPR038729, Rad50/SbcC_AAA

The PANTHER Classification System

More...
PANTHERi
PTHR11059, PTHR11059, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13476, AAA_23, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF003128, RecN, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540, SSF52540, 2 hits

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00634, recN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P17894-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLAELSIKNF AIIEELTVSF ERGLTVLTGE TGAGKSIIID AISLLVGGRG
60 70 80 90 100
SSEFVRYGEA KAELEGLFLL ESGHPVLGVC AEQGIDVSDE MIVMRRDIST
110 120 130 140 150
SGKSVCRVNG KLVTIASLRE IGRLLLDIHG QHDNQLLMED ENHLQLLDKF
160 170 180 190 200
AGAEVESALK TYQEGYQRYV KLLKKLKQLS ESEQEMAHRL DLIQFQLEEI
210 220 230 240 250
ESAKLELNED EQLQEERQQI SNFEKIYESL QNAYNALRSE QGGLDWVGMA
260 270 280 290 300
SAQLEDISDI NEPLKKMSES VSNSYYLLED ATFQMRNMLD ELEFDPERLN
310 320 330 340 350
YIETRLNEIK QLKRKYGATV EDILEYASKI EEEIDQIENR DSHLQSLKKE
360 370 380 390 400
LDSVGKDVAV EAANVSQIRK TWAKKLADEI HRELKSLYME KSTFDTEFKV
410 420 430 440 450
RTASRNEEAP LVNGQPVQLT EQGIDLVKFL ISTNTGEPLK SLSKVASGGE
460 470 480 490 500
LSRVMLAIKS IFSSQQDVTS IIFDEVDTGV SGRVAQAIAE KIHKVSIGSQ
510 520 530 540 550
VLCITHLPQV AAMADTHLYI AKELKDGRTT TRVKPLSKQE KVAEIGRMIA
560 570
GVEVTDLTKR HAKELLKQAD QVKTTG
Length:576
Mass (Da):64,508
Last modified:June 16, 2009 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i235BED4E4A2EB17D
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti74H → L in AAA22209 (PubMed:2507400).Curated1
Sequence conflicti104 – 111SVCRVNGK → AFAVSMAS in AAA22209 (PubMed:2507400).Curated8
Sequence conflicti189R → L in AAA22691 (PubMed:2106508).Curated1
Sequence conflicti189R → L in BAA12579 (PubMed:8969508).Curated1
Sequence conflicti546 – 548GRM → ERS in AAA22691 (PubMed:2106508).Curated3
Sequence conflicti546 – 548GRM → ERS in BAA12579 (PubMed:8969508).Curated3
Sequence conflicti546 – 548GRM → ERS in AAC44870 (PubMed:9044256).Curated3

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
M30297 Genomic DNA Translation: AAA22691.1
D84432 Genomic DNA Translation: BAA12579.1
AL009126 Genomic DNA Translation: CAB14355.2
M27869 Genomic DNA Translation: AAA22209.1
U68235 Genomic DNA Translation: AAC44870.1

Protein sequence database of the Protein Information Resource

More...
PIRi
B35128

NCBI Reference Sequences

More...
RefSeqi
NP_390304.2, NC_000964.3
WP_003230267.1, NZ_JNCM01000036.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
CAB14355; CAB14355; BSU_24240

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
938656

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
bsu:BSU24240

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|224308.179.peg.2642

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M30297 Genomic DNA Translation: AAA22691.1
D84432 Genomic DNA Translation: BAA12579.1
AL009126 Genomic DNA Translation: CAB14355.2
M27869 Genomic DNA Translation: AAA22209.1
U68235 Genomic DNA Translation: AAC44870.1
PIRiB35128
RefSeqiNP_390304.2, NC_000964.3
WP_003230267.1, NZ_JNCM01000036.1

3D structure databases

SMRiP17894
ModBaseiSearch...

Protein-protein interaction databases

STRINGi224308.BSU24240

Proteomic databases

jPOSTiP17894
PaxDbiP17894
PRIDEiP17894

Genome annotation databases

EnsemblBacteriaiCAB14355; CAB14355; BSU_24240
GeneIDi938656
KEGGibsu:BSU24240
PATRICifig|224308.179.peg.2642

Phylogenomic databases

eggNOGiCOG0497, Bacteria
InParanoidiP17894
OMAiQVICVTH
PhylomeDBiP17894

Enzyme and pathway databases

BioCyciBSUB:BSU24240-MONOMER

Family and domain databases

Gene3Di3.40.50.300, 2 hits
InterProiView protein in InterPro
IPR004604, DNA_recomb/repair_RecN
IPR027417, P-loop_NTPase
IPR038729, Rad50/SbcC_AAA
PANTHERiPTHR11059, PTHR11059, 1 hit
PfamiView protein in Pfam
PF13476, AAA_23, 1 hit
PIRSFiPIRSF003128, RecN, 1 hit
SUPFAMiSSF52540, SSF52540, 2 hits
TIGRFAMsiTIGR00634, recN, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRECN_BACSU
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P17894
Secondary accession number(s): P19671, P71027
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1990
Last sequence update: June 16, 2009
Last modified: September 29, 2021
This is version 130 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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