Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 180 (13 Feb 2019)
Sequence version 3 (05 May 2009)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein

Transcription factor jun-D

Gene

JUND

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Transcription factor binding AP-1 sites.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • DNA-binding transcription factor activity, RNA polymerase II-specific Source: NTNU_SB
  • enzyme binding Source: UniProtKB
  • RNA polymerase II proximal promoter sequence-specific DNA binding Source: GO_Central
  • transcription coactivator activity Source: GO_Central
  • transcription factor binding Source: GO_Central
  • transcription regulatory region DNA binding Source: UniProtKB

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActivator, DNA-binding
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-9018519 Estrogen-dependent gene expression

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...
SignaLinki
P17535

SIGNOR Signaling Network Open Resource

More...
SIGNORi
P17535

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transcription factor jun-D
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:JUND
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000130522.5

Human Gene Nomenclature Database

More...
HGNCi
HGNC:6206 JUND

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
165162 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P17535

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
3727

Open Targets

More...
OpenTargetsi
ENSG00000130522

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA30008

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
JUND

Domain mapping of disease mutations (DMDM)

More...
DMDMi
229462969

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000764421 – 347Transcription factor jun-DAdd BLAST347

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei251PhosphoserineCombined sources1
Modified residuei255PhosphoserineCombined sources1
Modified residuei259PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P17535

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
P17535

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P17535

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P17535

PeptideAtlas

More...
PeptideAtlasi
P17535

PRoteomics IDEntifications database

More...
PRIDEi
P17535

ProteomicsDB human proteome resource

More...
ProteomicsDBi
53481

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P17535

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P17535

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000130522 Expressed in 247 organ(s), highest expression level in mammary gland

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P17535 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P17535 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
CAB005268
HPA063029

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Binds DNA as a dimer (By similarity). Interacts with MEN1; this interaction represses transcriptional activation.By similarity1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
109930, 48 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-497 Menin-JUND transcription inhibition complex

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
P17535

Database of interacting proteins

More...
DIPi
DIP-1053N

Protein interaction database and analysis system

More...
IntActi
P17535, 28 interactors

Molecular INTeraction database

More...
MINTi
P17535

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000252818

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1347
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3U86X-ray2.84B27-39[»]
5VPAX-ray2.83B266-332[»]
5VPBX-ray2.69B/D266-332[»]
5VPCX-ray2.50B/D266-332[»]
5VPDX-ray2.79B/D266-332[»]
5VPEX-ray2.05B/D266-332[»]
5VPFX-ray2.69B/D266-332[»]

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
P17535

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P17535

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini268 – 331bZIPPROSITE-ProRule annotationAdd BLAST64

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni268 – 295Basic motifPROSITE-ProRule annotationAdd BLAST28
Regioni296 – 324Leucine-zipperPROSITE-ProRule annotationAdd BLAST29

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi158 – 166Poly-Ala9

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the bZIP family. Jun subfamily.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0837 Eukaryota
ENOG410XRWH LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000162806

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000006648

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG001722

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P17535

KEGG Orthology (KO)

More...
KOi
K04449

Identification of Orthologs from Complete Genome Data

More...
OMAi
APVYANL

Database of Orthologous Groups

More...
OrthoDBi
1090460at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P17535

TreeFam database of animal gene trees

More...
TreeFami
TF323952

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR004827 bZIP
IPR005643 JNK
IPR029823 JunD
IPR002112 Leuzip_Jun
IPR008917 TF_DNA-bd_sf

The PANTHER Classification System

More...
PANTHERi
PTHR11462:SF7 PTHR11462:SF7, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00170 bZIP_1, 1 hit
PF03957 Jun, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00043 LEUZIPPRJUN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00338 BRLZ, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47454 SSF47454, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50217 BZIP, 1 hit
PS00036 BZIP_BASIC, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

P17535-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
METPFYGDEA LSGLGGGASG SGGSFASPGR LFPGAPPTAA AGSMMKKDAL
60 70 80 90 100
TLSLSEQVAA ALKPAAAPPP TPLRADGAPS AAPPDGLLAS PDLGLLKLAS
110 120 130 140 150
PELERLIIQS NGLVTTTPTS SQFLYPKVAA SEEQEFAEGF VKALEDLHKQ
160 170 180 190 200
NQLGAGAAAA AAAAAAGGPS GTATGSAPPG ELAPAAAAPE APVYANLSSY
210 220 230 240 250
AGGAGGAGGA ATVAFAAEPV PFPPPPPPGA LGPPRLAALK DEPQTVPDVP
260 270 280 290 300
SFGESPPLSP IDMDTQERIK AERKRLRNRI AASKCRKRKL ERISRLEEKV
310 320 330 340
KTLKSQNTEL ASTASLLREQ VAQLKQKVLS HVNSGCQLLP QHQVPAY
Length:347
Mass (Da):35,174
Last modified:May 5, 2009 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFE85A1AA2B5B9597
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
U3KPR5U3KPR5_HUMAN
Transcription factor jun-D
JUND
166Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence CAA40010 differs from that shown. Reason: Frameshift at several positions.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti24S → T in CAA40010 (PubMed:1903194).Curated1
Sequence conflicti157A → R in CAA40010 (PubMed:1903194).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_05524720G → V1 PublicationCorresponds to variant dbSNP:rs41478151Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X56681 mRNA Translation: CAA40010.1 Frameshift.
EF044249 Genomic DNA Translation: ABJ53425.1
AK223630 mRNA Translation: BAD97350.1
CH471106 Genomic DNA Translation: EAW84684.1
X51346 mRNA Translation: CAA35739.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS32959.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A43815
S10184 TVHUJD

NCBI Reference Sequences

More...
RefSeqi
NP_001273897.1, NM_001286968.1
NP_005345.3, NM_005354.5

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.2780

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000252818; ENSP00000252818; ENSG00000130522

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
3727

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:3727

UCSC genome browser

More...
UCSCi
uc002nip.4 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross_references_section">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

NIEHS-SNPs
Atlas of Genetics and Cytogenetics in Oncology and Haematology

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X56681 mRNA Translation: CAA40010.1 Frameshift.
EF044249 Genomic DNA Translation: ABJ53425.1
AK223630 mRNA Translation: BAD97350.1
CH471106 Genomic DNA Translation: EAW84684.1
X51346 mRNA Translation: CAA35739.1
CCDSiCCDS32959.1
PIRiA43815
S10184 TVHUJD
RefSeqiNP_001273897.1, NM_001286968.1
NP_005345.3, NM_005354.5
UniGeneiHs.2780

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3U86X-ray2.84B27-39[»]
5VPAX-ray2.83B266-332[»]
5VPBX-ray2.69B/D266-332[»]
5VPCX-ray2.50B/D266-332[»]
5VPDX-ray2.79B/D266-332[»]
5VPEX-ray2.05B/D266-332[»]
5VPFX-ray2.69B/D266-332[»]
ProteinModelPortaliP17535
SMRiP17535
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi109930, 48 interactors
ComplexPortaliCPX-497 Menin-JUND transcription inhibition complex
CORUMiP17535
DIPiDIP-1053N
IntActiP17535, 28 interactors
MINTiP17535
STRINGi9606.ENSP00000252818

PTM databases

iPTMnetiP17535
PhosphoSitePlusiP17535

Polymorphism and mutation databases

BioMutaiJUND
DMDMi229462969

Proteomic databases

EPDiP17535
jPOSTiP17535
MaxQBiP17535
PaxDbiP17535
PeptideAtlasiP17535
PRIDEiP17535
ProteomicsDBi53481

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000252818; ENSP00000252818; ENSG00000130522
GeneIDi3727
KEGGihsa:3727
UCSCiuc002nip.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
3727
DisGeNETi3727
EuPathDBiHostDB:ENSG00000130522.5

GeneCards: human genes, protein and diseases

More...
GeneCardsi
JUND

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0040163
HGNCiHGNC:6206 JUND
HPAiCAB005268
HPA063029
MIMi165162 gene
neXtProtiNX_P17535
OpenTargetsiENSG00000130522
PharmGKBiPA30008

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG0837 Eukaryota
ENOG410XRWH LUCA
GeneTreeiENSGT00940000162806
HOGENOMiHOG000006648
HOVERGENiHBG001722
InParanoidiP17535
KOiK04449
OMAiAPVYANL
OrthoDBi1090460at2759
PhylomeDBiP17535
TreeFamiTF323952

Enzyme and pathway databases

ReactomeiR-HSA-9018519 Estrogen-dependent gene expression
SignaLinkiP17535
SIGNORiP17535

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
JUND human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
JunD

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
3727

Protein Ontology

More...
PROi
PR:P17535

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000130522 Expressed in 247 organ(s), highest expression level in mammary gland
ExpressionAtlasiP17535 baseline and differential
GenevisibleiP17535 HS

Family and domain databases

InterProiView protein in InterPro
IPR004827 bZIP
IPR005643 JNK
IPR029823 JunD
IPR002112 Leuzip_Jun
IPR008917 TF_DNA-bd_sf
PANTHERiPTHR11462:SF7 PTHR11462:SF7, 1 hit
PfamiView protein in Pfam
PF00170 bZIP_1, 1 hit
PF03957 Jun, 1 hit
PRINTSiPR00043 LEUZIPPRJUN
SMARTiView protein in SMART
SM00338 BRLZ, 1 hit
SUPFAMiSSF47454 SSF47454, 1 hit
PROSITEiView protein in PROSITE
PS50217 BZIP, 1 hit
PS00036 BZIP_BASIC, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiJUND_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P17535
Secondary accession number(s): Q53EK9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1990
Last sequence update: May 5, 2009
Last modified: February 13, 2019
This is version 180 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  5. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  6. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again