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Entry version 190 (16 Oct 2019)
Sequence version 3 (24 Mar 2009)
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Protein

Zinc finger and SCAN domain-containing protein 20

Gene

ZSCAN20

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri710 – 732C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri738 – 760C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri766 – 788C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri794 – 816C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri875 – 897C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri903 – 925C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri931 – 953C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri959 – 981C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri987 – 1009C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri1015 – 1037C2H2-type 10PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger and SCAN domain-containing protein 20
Alternative name(s):
Zinc finger protein 31
Zinc finger protein 360
Zinc finger protein KOX29
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZSCAN20
Synonyms:KOX29, ZNF31, ZNF360
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:13093 ZSCAN20

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
611315 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P17040

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
7579

Open Targets

More...
OpenTargetsi
ENSG00000121903

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA37668

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
P17040

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZSCAN20

Domain mapping of disease mutations (DMDM)

More...
DMDMi
229485383

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000473601 – 1043Zinc finger and SCAN domain-containing protein 20Add BLAST1043

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
P17040

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
P17040

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P17040

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P17040

PeptideAtlas

More...
PeptideAtlasi
P17040

PRoteomics IDEntifications database

More...
PRIDEi
P17040

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
53445 [P17040-1]
53446 [P17040-2]
53447 [P17040-3]
53448 [P17040-4]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P17040

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P17040

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000121903 Expressed in 101 organ(s), highest expression level in sperm

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P17040 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA017933

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
A0A0S2Z6X03EBI-16440054,EBI-16431094

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
113408, 60 interactors

Protein interaction database and analysis system

More...
IntActi
P17040, 54 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000355053

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P17040

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini51 – 133SCAN boxPROSITE-ProRule annotationAdd BLAST83

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri710 – 732C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri738 – 760C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri766 – 788C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri794 – 816C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri875 – 897C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri903 – 925C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri931 – 953C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri959 – 981C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri987 – 1009C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri1015 – 1037C2H2-type 10PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721 Eukaryota
COG5048 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000161580

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P17040

KEGG Orthology (KO)

More...
KOi
K09230

Identification of Orthologs from Complete Genome Data

More...
OMAi
DWHREAQ

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P17040

TreeFam database of animal gene trees

More...
TreeFami
TF337082

Family and domain databases

Conserved Domains Database

More...
CDDi
cd07936 SCAN, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.4020.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001005 SANT/Myb
IPR003309 SCAN_dom
IPR038269 SCAN_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02023 SCAN, 1 hit
PF00096 zf-C2H2, 10 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00717 SANT, 2 hits
SM00431 SCAN, 1 hit
SM00355 ZnF_C2H2, 10 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57667 SSF57667, 6 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50804 SCAN_BOX, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 10 hits
PS50157 ZINC_FINGER_C2H2_2, 10 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: P17040-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAMALELQAQ ASPQPEPEEL LIVKLEEDSW GSESKLWEKD RGSVSGPEAS
60 70 80 90 100
RQRFRQFQYR DAAGPHEAFS QLWALCCRWL RPEIRLKEQI LELLVLEQFL
110 120 130 140 150
TILPREVQTW VQARHPESGE EAVALVEDWH RETRTAGQSG LELHTEETRP
160 170 180 190 200
LKTGEEAQSF QLQPVDPWPE GQSQKKGVKN TCPDLPNHLN AEVAPQPLKE
210 220 230 240 250
SAVLTPRVPT LPKMGSVGDW EVTAESQEAL GPGKHAEKEL CKDPPGDDCG
260 270 280 290 300
NSVCLGVPVS KPSNTSEKEQ GPEFWGLSLI NSGKRSTADY SLDNEPAQAL
310 320 330 340 350
TWRDSRAWEE QYQWDVEDMK VSGVHWGYEE TKTFLAILSE SPFSEKLRTC
360 370 380 390 400
HQNRQVYRAI AEQLRARGFL RTLEQCRYRV KNLLRNYRKA KSSHPPGTCP
410 420 430 440 450
FYEELEALVR ARTAIRATDG PGEAVALPRL GYSDAEMDEQ EEGGWDPEEM
460 470 480 490 500
AEDCNGAGLV NVESTQGPRI AGAPALFQSR IAGVHWGYEE TKAFLAILSE
510 520 530 540 550
SPFSEKLRTC HQNSQVYRAI AERLCALGFL RTLEQCRYRF KNLLRSYRKA
560 570 580 590 600
KSSHPPGTCP FYEELDSLMR ARAAVRAMGT VREAAGLPRC GQSSAETDAQ
610 620 630 640 650
EAWGEVANED AVKPSTLCPK APDMGFEMRH EDEDQISEQD IFEGLPGALS
660 670 680 690 700
KCPTEAVCQP LDWGEDSENE NEDEGQWGNP SQEQWQESSS EEDLEKLIDH
710 720 730 740 750
QGLYLAEKPY KCDTCMKSFS RSSHFIAHQR IHTGEKPYKC LECGKNFSDR
760 770 780 790 800
SNLNTHQRIH TGEKPYKCLE CGKSFSDHSN LITHQRIHTG EKPYKCGECW
810 820 830 840 850
KSFNQSSNLL KHQRIHLGGN PDQCSEPGGN FAQSPSFSAH WRNSTEETAP
860 870 880 890 900
EQPQSISKDL NSPGPHSTNS GEKLYECSEC GRSFSKSSAL ISHQRIHTGE
910 920 930 940 950
KPYECAECGK SFSKSSTLAN HQRTHTGEKP YKCVDCGKCF SERSKLITHQ
960 970 980 990 1000
RVHTGEKPYK CLECGKFFRD RSNLITHQRI HTGEKPYKCR ECGKCFNQSS
1010 1020 1030 1040
SLIIHQRIHT GEKPYKCTEC GKDFNNSSHF SAHRRTHAGG KAS
Length:1,043
Mass (Da):117,541
Last modified:March 24, 2009 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1598FB5F243773FE
GO
Isoform 2 (identifier: P17040-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     25-90: Missing.

Show »
Length:977
Mass (Da):109,706
Checksum:i5E283FEE045D4525
GO
Isoform 3 (identifier: P17040-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     482-482: Missing.

Note: No experimental confirmation available.
Show »
Length:1,042
Mass (Da):117,470
Checksum:i68BCA6E9110E3EB0
GO
Isoform 4 (identifier: P17040-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     202-255: Missing.
     482-487: AGVHWG → GKNMGV
     488-1043: Missing.

Note: No experimental confirmation available.
Show »
Length:433
Mass (Da):49,035
Checksum:i63C40A82025DB27B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti100L → P in BAF82884 (PubMed:14702039).Curated1
Sequence conflicti126V → M in BAF82884 (PubMed:14702039).Curated1
Sequence conflicti740C → R in BAD18552 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_054799248D → N. Corresponds to variant dbSNP:rs34446695Ensembl.1
Natural variantiVAR_054800432Y → D3 PublicationsCorresponds to variant dbSNP:rs4403594Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_03673525 – 90Missing in isoform 2. 1 PublicationAdd BLAST66
Alternative sequenceiVSP_036736202 – 255Missing in isoform 4. 1 PublicationAdd BLAST54
Alternative sequenceiVSP_036737482 – 487AGVHWG → GKNMGV in isoform 4. 1 Publication6
Alternative sequenceiVSP_036738482Missing in isoform 3. 1 Publication1
Alternative sequenceiVSP_036739488 – 1043Missing in isoform 4. 1 PublicationAdd BLAST556

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK131405 mRNA Translation: BAD18552.1
AK290195 mRNA Translation: BAF82884.1
AC115285 Genomic DNA No translation available.
AL138837 Genomic DNA No translation available.
CH471059 Genomic DNA Translation: EAX07454.1
BC008827 mRNA Translation: AAH08827.1
BC011404 mRNA Translation: AAH11404.1
X52360 mRNA Translation: CAA36586.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS41300.1 [P17040-1]

Protein sequence database of the Protein Information Resource

More...
PIRi
I37969

NCBI Reference Sequences

More...
RefSeqi
NP_660281.2, NM_145238.3 [P17040-1]
XP_005271228.1, XM_005271171.3 [P17040-3]
XP_006710937.1, XM_006710874.3 [P17040-1]
XP_016857726.1, XM_017002237.1 [P17040-1]
XP_016857727.1, XM_017002238.1 [P17040-3]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000361328; ENSP00000355053; ENSG00000121903 [P17040-1]
ENST00000373413; ENSP00000362512; ENSG00000121903 [P17040-4]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
7579

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:7579

UCSC genome browser

More...
UCSCi
uc001bxj.5 human [P17040-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK131405 mRNA Translation: BAD18552.1
AK290195 mRNA Translation: BAF82884.1
AC115285 Genomic DNA No translation available.
AL138837 Genomic DNA No translation available.
CH471059 Genomic DNA Translation: EAX07454.1
BC008827 mRNA Translation: AAH08827.1
BC011404 mRNA Translation: AAH11404.1
X52360 mRNA Translation: CAA36586.1
CCDSiCCDS41300.1 [P17040-1]
PIRiI37969
RefSeqiNP_660281.2, NM_145238.3 [P17040-1]
XP_005271228.1, XM_005271171.3 [P17040-3]
XP_006710937.1, XM_006710874.3 [P17040-1]
XP_016857726.1, XM_017002237.1 [P17040-1]
XP_016857727.1, XM_017002238.1 [P17040-3]

3D structure databases

SMRiP17040
ModBaseiSearch...

Protein-protein interaction databases

BioGridi113408, 60 interactors
IntActiP17040, 54 interactors
STRINGi9606.ENSP00000355053

PTM databases

iPTMnetiP17040
PhosphoSitePlusiP17040

Polymorphism and mutation databases

BioMutaiZSCAN20
DMDMi229485383

Proteomic databases

jPOSTiP17040
MassIVEiP17040
MaxQBiP17040
PaxDbiP17040
PeptideAtlasiP17040
PRIDEiP17040
ProteomicsDBi53445 [P17040-1]
53446 [P17040-2]
53447 [P17040-3]
53448 [P17040-4]

Protocols and materials databases

ABCD curated depository of sequenced antibodies

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ABCDi
P17040

Genome annotation databases

EnsembliENST00000361328; ENSP00000355053; ENSG00000121903 [P17040-1]
ENST00000373413; ENSP00000362512; ENSG00000121903 [P17040-4]
GeneIDi7579
KEGGihsa:7579
UCSCiuc001bxj.5 human [P17040-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
7579
DisGeNETi7579

GeneCards: human genes, protein and diseases

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GeneCardsi
ZSCAN20
HGNCiHGNC:13093 ZSCAN20
HPAiHPA017933
MIMi611315 gene
neXtProtiNX_P17040
OpenTargetsiENSG00000121903
PharmGKBiPA37668

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00940000161580
InParanoidiP17040
KOiK09230
OMAiDWHREAQ
OrthoDBi1318335at2759
PhylomeDBiP17040
TreeFamiTF337082

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
7579
PharosiP17040

Protein Ontology

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PROi
PR:P17040

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000121903 Expressed in 101 organ(s), highest expression level in sperm
GenevisibleiP17040 HS

Family and domain databases

CDDicd07936 SCAN, 1 hit
Gene3Di1.10.4020.10, 1 hit
InterProiView protein in InterPro
IPR001005 SANT/Myb
IPR003309 SCAN_dom
IPR038269 SCAN_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF02023 SCAN, 1 hit
PF00096 zf-C2H2, 10 hits
SMARTiView protein in SMART
SM00717 SANT, 2 hits
SM00431 SCAN, 1 hit
SM00355 ZnF_C2H2, 10 hits
SUPFAMiSSF57667 SSF57667, 6 hits
PROSITEiView protein in PROSITE
PS50804 SCAN_BOX, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 10 hits
PS50157 ZINC_FINGER_C2H2_2, 10 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZSC20_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P17040
Secondary accession number(s): A8K2D0
, B1ALI4, B1ALI5, B1ALI6, Q6ZN23, Q96FA9, Q96H84
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1990
Last sequence update: March 24, 2009
Last modified: October 16, 2019
This is version 190 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. SIMILARITY comments
    Index of protein domains and families
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
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