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UniProtKB - P17024 (ZNF20_HUMAN)

Entry version 194 (07 Apr 2021)
Sequence version 2 (01 Dec 2000)
Previous versions | rss
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Protein

Zinc finger protein 20

Gene

ZNF20

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri103 – 130C2H2-type 1; atypicalPROSITE-ProRule annotationAdd BLAST28
Zinc fingeri143 – 165C2H2-type 2; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri171 – 193C2H2-type 3; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri199 – 221C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri227 – 249C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri255 – 277C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri283 – 305C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri311 – 333C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri339 – 361C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri367 – 389C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri395 – 417C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri423 – 445C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri451 – 473C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri479 – 500C2H2-type 14PROSITE-ProRule annotationAdd BLAST22
Zinc fingeri506 – 528C2H2-type 15PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		P17024

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-212436, Generic Transcription Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 20
Alternative name(s):
Zinc finger protein KOX13
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF20
Synonyms:KOX13
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:12992, ZNF20

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		194557, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_P17024

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000132010.15

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		7568

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA37572

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		P17024, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		ZNF20

Domain mapping of disease mutations (DMDM)

More...DMDMi		12643268

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000473441 – 532Zinc finger protein 20Add BLAST532

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		P17024

MaxQB - The MaxQuant DataBase

More...MaxQBi		P17024

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P17024

PeptideAtlas

More...PeptideAtlasi		P17024

PRoteomics IDEntifications database

More...PRIDEi		P17024

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		53424

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		P17024

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		P17024

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000132010, Expressed in sural nerve and 116 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		P17024, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		P17024, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000132010, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details
P17024
With#Exp.IntAct
ACTA1 [P68133]3EBI-717634,EBI-367510
AHSP [Q9NZD4]3EBI-717634,EBI-720250
ATP1A3 [P13637]3EBI-717634,EBI-948169
C1orf109 [Q9NX04]3EBI-717634,EBI-8643161
CARD9 - isoform 2 [Q9H257-2]3EBI-717634,EBI-11530605
CCDC102B [Q68D86]6EBI-717634,EBI-10171570
CCDC136 - isoform 2 [Q96JN2-2]3EBI-717634,EBI-10171416
CCNDBP1 [O95273]6EBI-717634,EBI-748961
CEP70 [Q8NHQ1]3EBI-717634,EBI-739624
CRACR2A [Q9BSW2]3EBI-717634,EBI-739773
DMWD [G5E9A7]3EBI-717634,EBI-10976677
FSD2 [A1L4K1]3EBI-717634,EBI-5661036
GEM [P55040]3EBI-717634,EBI-744104
GFAP [P14136]3EBI-717634,EBI-744302
GOLGA6L9 [A6NEM1]3EBI-717634,EBI-5916454
GPSM3 [Q9Y4H4]3EBI-717634,EBI-347538
JPH3 [Q8WXH2]3EBI-717634,EBI-1055254
KIFC3 [Q9BVG8]3EBI-717634,EBI-2125614
KIFC3 - isoform 4 [Q9BVG8-5]3EBI-717634,EBI-14069005
KRT31 [Q15323]3EBI-717634,EBI-948001
KRT38 [O76015]3EBI-717634,EBI-1047263
KRT40 [Q6A162]3EBI-717634,EBI-10171697
KRTAP10-5 [P60370]3EBI-717634,EBI-10172150
KRTAP10-7 [P60409]3EBI-717634,EBI-10172290
KRTAP10-8 [P60410]6EBI-717634,EBI-10171774
KRTAP10-9 [P60411]3EBI-717634,EBI-10172052
KRTAP12-3 [P60328]3EBI-717634,EBI-11953334
KRTAP4-12 [Q9BQ66]3EBI-717634,EBI-739863
KRTAP4-2 [Q9BYR5]3EBI-717634,EBI-10172511
KRTAP9-2 [Q9BYQ4]3EBI-717634,EBI-1044640
LMNA [P02545]3EBI-717634,EBI-351935
LZTS2 [Q9BRK4]3EBI-717634,EBI-741037
MTUS2 [Q5JR59]3EBI-717634,EBI-742948
MTUS2 - isoform 2 [Q5JR59-3]3EBI-717634,EBI-11522433
NF2 [P35240]3EBI-717634,EBI-1014472
PECAM1 [P16284]3EBI-717634,EBI-716404
RAB5A [P20339]3EBI-717634,EBI-399437
SCNM1 [Q9BWG6]3EBI-717634,EBI-748391
SOGA1 - isoform 4 [O94964-4]3EBI-717634,EBI-14083835
SPRED1 [Q7Z699]3EBI-717634,EBI-5235340
TEKT4 [Q8WW24]3EBI-717634,EBI-750487
TRAF1 [Q13077]6EBI-717634,EBI-359224
TRIM23 [P36406]3EBI-717634,EBI-740098
TXLNB [Q8N3L3]3EBI-717634,EBI-6116822
VIM [P08670]3EBI-717634,EBI-353844
VWC2L [B2RUY7]3EBI-717634,EBI-11747707
VWCE [Q96DN2]3EBI-717634,EBI-2850497
YARS1 [P54577]3EBI-717634,EBI-1048893
ZNF417 [Q8TAU3]3EBI-717634,EBI-740727

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		113399, 41 interactors

Protein interaction database and analysis system

More...IntActi		P17024, 51 interactors

Molecular INTeraction database

More...MINTi		P17024

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000335437

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		P17024, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P17024

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini7 – 78KRABPROSITE-ProRule annotationAdd BLAST72

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the krueppel C2H2-type zinc-finger protein family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri103 – 130C2H2-type 1; atypicalPROSITE-ProRule annotationAdd BLAST28
Zinc fingeri143 – 165C2H2-type 2; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri171 – 193C2H2-type 3; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri199 – 221C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri227 – 249C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri255 – 277C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri283 – 305C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri311 – 333C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri339 – 361C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri367 – 389C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri395 – 417C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri423 – 445C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri451 – 473C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri479 – 500C2H2-type 14PROSITE-ProRule annotationAdd BLAST22
Zinc fingeri506 – 528C2H2-type 15PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1721, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000164761

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_002678_44_3_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P17024

Identification of Orthologs from Complete Genome Data

More...OMAi		QSHDEAC

Database of Orthologous Groups

More...OrthoDBi		1318335at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		P17024

TreeFam database of animal gene trees

More...TreeFami		TF338854

Family and domain databases

Conserved Domains Database

More...CDDi		cd07765, KRAB_A-box, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR001909, KRAB
IPR036051, KRAB_dom_sf
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01352, KRAB, 1 hit
PF00096, zf-C2H2, 5 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00349, KRAB, 1 hit
SM00355, ZnF_C2H2, 14 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF109640, SSF109640, 1 hit
SSF57667, SSF57667, 8 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50805, KRAB, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 11 hits
PS50157, ZINC_FINGER_C2H2_2, 15 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

P17024-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMFQDSVAFE DVAVSFTQEE WALLDPSQKN LYRDVMQETF KNLTSVGKTW 
        60         70         80         90        100
KVQNIEDEYK NPRRNLSLMR EKLCESKESH HCGESFNQIA DDMLNRKTLP 
       110        120        130        140        150
GITPCESSVC GEVGTGHSSL NTHIRADTGH KSSEYQEYGE NPYRNKECKK 
       160        170        180        190        200
AFSYLDSFQS HDKACTKEKP YDGKECTETF ISHSCIQRHR VMHSGDGPYK 
       210        220        230        240        250
CKFCGKAFYF LNLCLIHERI HTGVKPYKCK QCGKAFTRST TLPVHERTHT 
       260        270        280        290        300
GVNADECKEC GNAFSFPSEI RRHKRSHTGE KPYECKQCGK VFISFSSIQY 
       310        320        330        340        350
HKMTHTGEKP YECKQCGKAF RCGSHLQKHG RTHTGEKPYE CRQCGKAFRC 
       360        370        380        390        400
TSDLQRHEKT HTEDKPYGCK QCGKGFRCAS QLQIHERTHS GEKPHECKEC 
       410        420        430        440        450
GKVFKYFSSL RIHERTHTGE KPHECKQCGK AFRYFSSLHI HERTHTGDKP 
       460        470        480        490        500
YECKVCGKAF TCSSSIRYHE RTHTGEKPYE CKHCGKAFIS NYIRYHERTH 
       510        520        530 
TGEKPYQCKQ CGKAFIRASS CREHERTHTI NR
Length:532
Mass (Da):61,567
Last modified:December 1, 2000 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC92473E875FCAA42
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
C9JIP4C9JIP4_HUMAN
Zinc finger protein 20
ZNF20
169Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0QYR3M0QYR3_HUMAN
Zinc finger protein 20
ZNF20
131Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8WDZ5F8WDZ5_HUMAN
Zinc finger protein 20
ZNF20
40Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AL080125 mRNA Translation: CAB45723.2
CH471106 Genomic DNA Translation: EAW84260.1
BC036714 mRNA Translation: AAH36714.3
X52344 mRNA Translation: CAA36570.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS45986.1

Protein sequence database of the Protein Information Resource

More...PIRi		T12489

NCBI Reference Sequences

More...RefSeqi		NP_066966.2, NM_021143.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000334213; ENSP00000335437; ENSG00000132010

Database of genes from NCBI RefSeq genomes

More...GeneIDi		7568

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:7568

UCSC genome browser

More...UCSCi		uc002mtf.3, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL080125 mRNA Translation: CAB45723.2
CH471106 Genomic DNA Translation: EAW84260.1
BC036714 mRNA Translation: AAH36714.3
X52344 mRNA Translation: CAA36570.1
CCDSiCCDS45986.1
PIRiT12489
RefSeqiNP_066966.2, NM_021143.3

3D structure databases

SMRiP17024
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi113399, 41 interactors
IntActiP17024, 51 interactors
MINTiP17024
STRINGi9606.ENSP00000335437

PTM databases

iPTMnetiP17024
PhosphoSitePlusiP17024

Genetic variation databases

BioMutaiZNF20
DMDMi12643268

Proteomic databases

MassIVEiP17024
MaxQBiP17024
PaxDbiP17024
PeptideAtlasiP17024
PRIDEiP17024
ProteomicsDBi53424

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		6988, 70 antibodies

Genome annotation databases

EnsembliENST00000334213; ENSP00000335437; ENSG00000132010
GeneIDi7568
KEGGihsa:7568
UCSCiuc002mtf.3, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		7568
DisGeNETi7568

GeneCards: human genes, protein and diseases

More...GeneCardsi		ZNF20
HGNCiHGNC:12992, ZNF20
HPAiENSG00000132010, Low tissue specificity
MIMi194557, gene
neXtProtiNX_P17024
PharmGKBiPA37572
VEuPathDBiHostDB:ENSG00000132010.15

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG1721, Eukaryota
GeneTreeiENSGT00940000164761
HOGENOMiCLU_002678_44_3_1
InParanoidiP17024
OMAiQSHDEAC
OrthoDBi1318335at2759
PhylomeDBiP17024
TreeFamiTF338854

Enzyme and pathway databases

PathwayCommonsiP17024
ReactomeiR-HSA-212436, Generic Transcription Pathway

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		7568, 10 hits in 1006 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		7568
PharosiP17024, Tdark

Protein Ontology

More...PROi		PR:P17024
RNActiP17024, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000132010, Expressed in sural nerve and 116 other tissues
ExpressionAtlasiP17024, baseline and differential
GenevisibleiP17024, HS

Family and domain databases

CDDicd07765, KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909, KRAB
IPR036051, KRAB_dom_sf
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF01352, KRAB, 1 hit
PF00096, zf-C2H2, 5 hits
SMARTiView protein in SMART
SM00349, KRAB, 1 hit
SM00355, ZnF_C2H2, 14 hits
SUPFAMiSSF109640, SSF109640, 1 hit
SSF57667, SSF57667, 8 hits
PROSITEiView protein in PROSITE
PS50805, KRAB, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 11 hits
PS50157, ZINC_FINGER_C2H2_2, 15 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZNF20_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P17024
Secondary accession number(s): Q8N457, Q9UG41
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1990
Last sequence update: December 1, 2000
Last modified: April 7, 2021
This is version 194 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families
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