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UniProtKB - P17019 (ZN708_HUMAN)

Entry version 179 (02 Dec 2020)
Sequence version 5 (24 Jul 2013)
Previous versions | rss
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Protein

Zinc finger protein 708

Gene

ZNF708

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri76 – 98C2H2-type 1; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri104 – 126C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri132 – 154C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri160 – 182C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri188 – 210C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri216 – 238C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri244 – 266C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri272 – 294C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri300 – 322C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri328 – 350C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri356 – 378C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri384 – 406C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri412 – 434C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri440 – 462C2H2-type 14PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri468 – 490C2H2-type 15PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		P17019

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-212436, Generic Transcription Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 708
Alternative name(s):
Zinc finger protein 15
Zinc finger protein 15-like 1
Zinc finger protein KOX8
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF708
Synonyms:KOX8, ZNF15, ZNF15L1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Eukaryotic Pathogen and Host Database Resources

More...EuPathDBi		HostDB:ENSG00000182141.9

Human Gene Nomenclature Database

More...HGNCi		HGNC:12945, ZNF708

neXtProt; the human protein knowledge platform

More...neXtProti		NX_P17019

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		P17019, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		ZNF708

Domain mapping of disease mutations (DMDM)

More...DMDMi		527504092

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000477061 – 499Zinc finger protein 708Add BLAST499

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei480PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		P17019

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		P17019

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		P17019

MaxQB - The MaxQuant DataBase

More...MaxQBi		P17019

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P17019

PeptideAtlas

More...PeptideAtlasi		P17019

PRoteomics IDEntifications database

More...PRIDEi		P17019

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		53415

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		P17019

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		P17019

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000182141, Expressed in corpus callosum and 171 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		P17019, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		P17019, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000182141, Tissue enhanced (brain)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		113394, 4 interactors

Protein interaction database and analysis system

More...IntActi		P17019, 2 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000349401

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		P17019, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P17019

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the krueppel C2H2-type zinc-finger protein family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri76 – 98C2H2-type 1; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri104 – 126C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri132 – 154C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri160 – 182C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri188 – 210C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri216 – 238C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri244 – 266C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri272 – 294C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri300 – 322C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri328 – 350C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri356 – 378C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri384 – 406C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri412 – 434C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri440 – 462C2H2-type 14PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri468 – 490C2H2-type 15PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1721, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_002678_44_5_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P17019

Database of Orthologous Groups

More...OrthoDBi		1318335at2759

TreeFam database of animal gene trees

More...TreeFami		TF342117

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00096, zf-C2H2, 13 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00355, ZnF_C2H2, 14 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF57667, SSF57667, 8 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 14 hits
PS50157, ZINC_FINGER_C2H2_2, 15 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

P17019-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKRHEMAAKP PAMCSHFAKD LRPEQYIKNS FQQVILRRYG KCGYQKGCKS 
        60         70         80         90        100
VDEHKLHKGG HKGLNRCVTT TQSKIVQCDK YVKVFHKYSN AKRHKIRHTG 
       110        120        130        140        150
KNPFKCKECG KSFCMLSQLT QHEIIHTGEK PYKCEECGKA FKKSSNLTNH 
       160        170        180        190        200
KIIHTGEKPY KCEECGKAFN QSSTLTRHKI IHTGEKLYKC EECGKAFNRS 
       210        220        230        240        250
SNLTKHKIVH TGEKPYKCEE CGKAFKQSSN LTNHKKIHTG EKPYKCGECG 
       260        270        280        290        300
KAFTLSSHLT THKRIHTGEK PYKCEECGKA FSVFSTLTKH KIIHTEEKPY 
       310        320        330        340        350
KCEECGKAFN RSSHLTNHKV IHTGEKPYKC EECGKAFTKS STLTYHKVIH 
       360        370        380        390        400
TGKKPYKCEE CGKAFSIFSI LTKHKVIHTE DKPYKCEECG KTFNYSSNFT 
       410        420        430        440        450
NHKKIHTGEK PYKCEECGKS FILSSHLTTH KIIHTGEKPY KCKECGKAFN 
       460        470        480        490 
QSSTLMKHKI IHTGEKPYKC EECGKAFNQS PNLTKHKRIH TKEKPYKCK
Length:499
Mass (Da):57,357
Last modified:July 24, 2013 - v5
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iED1ECC35F4CBA3F1
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
M0R2V2M0R2V2_HUMAN
Zinc finger protein 708
ZNF708
38Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0QYN4M0QYN4_HUMAN
Zinc finger protein 708
ZNF708
126Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0R1G3M0R1G3_HUMAN
Zinc finger protein 708
ZNF708
65Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAD18665 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_0547957A → V1 PublicationCorresponds to variant dbSNP:rs547516Ensembl.1
Natural variantiVAR_05479649K → E1 PublicationCorresponds to variant dbSNP:rs1781873Ensembl.1
Natural variantiVAR_05479758K → T. Corresponds to variant dbSNP:rs1781872Ensembl.1
Natural variantiVAR_05479866R → Q1 PublicationCorresponds to variant dbSNP:rs504280Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK131527 mRNA Translation: BAD18665.1 Different initiation.
AK095062 mRNA No translation available.
AC022432 Genomic DNA No translation available.
X52339 mRNA Translation: CAA36565.1

Protein sequence database of the Protein Information Resource

More...PIRi		I37976

NCBI Reference Sequences

More...RefSeqi		NP_001284489.1, NM_001297560.1
NP_001284490.1, NM_001297561.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000356929; ENSP00000349401; ENSG00000182141

Database of genes from NCBI RefSeq genomes

More...GeneIDi		7562

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:7562

UCSC genome browser

More...UCSCi		uc002npq.2, human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK131527 mRNA Translation: BAD18665.1 Different initiation.
AK095062 mRNA No translation available.
AC022432 Genomic DNA No translation available.
X52339 mRNA Translation: CAA36565.1
PIRiI37976
RefSeqiNP_001284489.1, NM_001297560.1
NP_001284490.1, NM_001297561.1

3D structure databases

SMRiP17019
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi113394, 4 interactors
IntActiP17019, 2 interactors
STRINGi9606.ENSP00000349401

PTM databases

iPTMnetiP17019
PhosphoSitePlusiP17019

Polymorphism and mutation databases

BioMutaiZNF708
DMDMi527504092

Proteomic databases

EPDiP17019
jPOSTiP17019
MassIVEiP17019
MaxQBiP17019
PaxDbiP17019
PeptideAtlasiP17019
PRIDEiP17019
ProteomicsDBi53415

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		28681, 93 antibodies

The DNASU plasmid repository

More...DNASUi		7562

Genome annotation databases

EnsembliENST00000356929; ENSP00000349401; ENSG00000182141
GeneIDi7562
KEGGihsa:7562
UCSCiuc002npq.2, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		7562
EuPathDBiHostDB:ENSG00000182141.9

GeneCards: human genes, protein and diseases

More...GeneCardsi		ZNF708
HGNCiHGNC:12945, ZNF708
HPAiENSG00000182141, Tissue enhanced (brain)
neXtProtiNX_P17019

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG1721, Eukaryota
HOGENOMiCLU_002678_44_5_1
InParanoidiP17019
OrthoDBi1318335at2759
TreeFamiTF342117

Enzyme and pathway databases

PathwayCommonsiP17019
ReactomeiR-HSA-212436, Generic Transcription Pathway

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		7562, 4 hits in 845 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		ZNF708, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		7562
PharosiP17019, Tdark

Protein Ontology

More...PROi		PR:P17019
RNActiP17019, protein

Gene expression databases

BgeeiENSG00000182141, Expressed in corpus callosum and 171 other tissues
ExpressionAtlasiP17019, baseline and differential
GenevisibleiP17019, HS

Family and domain databases

InterProiView protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF00096, zf-C2H2, 13 hits
SMARTiView protein in SMART
SM00355, ZnF_C2H2, 14 hits
SUPFAMiSSF57667, SSF57667, 8 hits
PROSITEiView protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 14 hits
PS50157, ZINC_FINGER_C2H2_2, 15 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN708_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P17019
Secondary accession number(s): Q6ZMR0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1990
Last sequence update: July 24, 2013
Last modified: December 2, 2020
This is version 179 of the entry and version 5 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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