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Entry version 187 (12 Aug 2020)
Sequence version 3 (30 Nov 2010)
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Protein

Zinc finger protein 14

Gene

ZNF14

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri103 – 125C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri141 – 163C2H2-type 2; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri169 – 191C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri197 – 217C2H2-type 4; atypicalPROSITE-ProRule annotationAdd BLAST21
Zinc fingeri223 – 245C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri251 – 273C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri279 – 301C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri307 – 329C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri335 – 357C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri363 – 385C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri391 – 413C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri419 – 441C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri447 – 469C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri475 – 497C2H2-type 14PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri503 – 525C2H2-type 15PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri531 – 553C2H2-type 16PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri559 – 581C2H2-type 17PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri587 – 609C2H2-type 18PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri615 – 637C2H2-type 19PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
P17017

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-212436, Generic Transcription Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 14
Alternative name(s):
Gonadotropin-inducible ovary transcription repressor 4
Short name:
GIOT-4
Zinc finger protein KOX6
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF14
Synonyms:GIOT4, KOX6
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000105708.8

Human Gene Nomenclature Database

More...
HGNCi
HGNC:12924, ZNF14

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
194556, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P17017

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
7561

Open Targets

More...
OpenTargetsi
ENSG00000105708

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA37511

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
P17017, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF14

Domain mapping of disease mutations (DMDM)

More...
DMDMi
313104250

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000473371 – 642Zinc finger protein 14Add BLAST642

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P17017

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
P17017

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
P17017

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P17017

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P17017

PeptideAtlas

More...
PeptideAtlasi
P17017

PRoteomics IDEntifications database

More...
PRIDEi
P17017

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
53414

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P17017

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P17017

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000105708, Expressed in secondary oocyte and 219 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P17017, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000105708, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
113393, 2 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000340514

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
P17017, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P17017

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini4 – 76KRABPROSITE-ProRule annotationAdd BLAST73

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri103 – 125C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri141 – 163C2H2-type 2; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri169 – 191C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri197 – 217C2H2-type 4; atypicalPROSITE-ProRule annotationAdd BLAST21
Zinc fingeri223 – 245C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri251 – 273C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri279 – 301C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri307 – 329C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri335 – 357C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri363 – 385C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri391 – 413C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri419 – 441C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri447 – 469C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri475 – 497C2H2-type 14PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri503 – 525C2H2-type 15PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri531 – 553C2H2-type 16PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri559 – 581C2H2-type 17PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri587 – 609C2H2-type 18PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri615 – 637C2H2-type 19PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000182755

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_002678_44_3_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P17017

KEGG Orthology (KO)

More...
KOi
K09228

Identification of Orthologs from Complete Genome Data

More...
OMAi
CHMVERL

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P17017

TreeFam database of animal gene trees

More...
TreeFami
TF343410

Family and domain databases

Conserved Domains Database

More...
CDDi
cd07765, KRAB_A-box, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001909, KRAB
IPR036051, KRAB_dom_sf
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01352, KRAB, 1 hit
PF00096, zf-C2H2, 12 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00349, KRAB, 1 hit
SM00355, ZnF_C2H2, 18 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF109640, SSF109640, 1 hit
SSF57667, SSF57667, 11 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50805, KRAB, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 17 hits
PS50157, ZINC_FINGER_C2H2_2, 19 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P17017-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDSVSFEDVA VNFTLEEWAL LDSSQKKLYE DVMQETFKNL VCLGKKWEDQ
60 70 80 90 100
DIEDDHRNQG KNRRCHMVER LCESRRGSKC GETTSQMPNV NINKETFTGA
110 120 130 140 150
KPHECSFCGR DFIHHSSLNR HMRSHTGQKP NEYQEYEKQP CKCKAVGKTF
160 170 180 190 200
SYHHCFRKHE RTHTGVKPYE CKQCGKAFIY YQPFQRHERT HAGQKPYECK
210 220 230 240 250
QCGKTFIYYQ SFQKHAHTGK KPYECKQCGK AFICYQSFQR HKRTHTGEKP
260 270 280 290 300
YECKQCGKAF SCPTYFRTHE RTHTGEKPYK CKECGKAFSF LSSFRRHKRT
310 320 330 340 350
HSGEKPYECK ECGKAFFYSA SFRAHVIIHT GARPYKCKEC GKAFNSSNSC
360 370 380 390 400
RVHERTHIGE KPYECKRCGK SFSWSISLRL HERTHTGEKP YECKQCHKTF
410 420 430 440 450
SFSSSLREHE TTHTGEKPYE CKQCGKTFSF SSSLQRHERT HNAEKPYECK
460 470 480 490 500
QCGKAFRCSS YFRIHERSHT GEKPYECKQC GKVFIRSSSF RLHERTHTGE
510 520 530 540 550
KPYECKLCGK TFSFSSSLRE HEKIHTGNKP FECKQCGKAF LRSSQIRLHE
560 570 580 590 600
RTHTGEKPYQ CKQCGKAFIS SSKFRMHERT HTGEKPYRCK QCGKAFRFSS
610 620 630 640
SVRIHERSHT GEKPYECKQC GKAFISSSHF RLHERTHMGE KV
Length:642
Mass (Da):75,353
Last modified:November 30, 2010 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i806374FBDC480CE3
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_054791274T → S1 PublicationCorresponds to variant dbSNP:rs12973901Ensembl.1
Natural variantiVAR_057381379R → Q. Corresponds to variant dbSNP:rs3752153Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB021644 mRNA Translation: BAA86990.1
AC011458 Genomic DNA No translation available.
CH471106 Genomic DNA Translation: EAW84858.1
BC136323 mRNA Translation: AAI36324.1
X52337 mRNA Translation: CAA36563.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS12409.1

Protein sequence database of the Protein Information Resource

More...
PIRi
I37974

NCBI Reference Sequences

More...
RefSeqi
NP_066358.2, NM_021030.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000344099; ENSP00000340514; ENSG00000105708

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
7561

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:7561

UCSC genome browser

More...
UCSCi
uc002nnk.2, human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB021644 mRNA Translation: BAA86990.1
AC011458 Genomic DNA No translation available.
CH471106 Genomic DNA Translation: EAW84858.1
BC136323 mRNA Translation: AAI36324.1
X52337 mRNA Translation: CAA36563.1
CCDSiCCDS12409.1
PIRiI37974
RefSeqiNP_066358.2, NM_021030.2

3D structure databases

SMRiP17017
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi113393, 2 interactors
STRINGi9606.ENSP00000340514

PTM databases

iPTMnetiP17017
PhosphoSitePlusiP17017

Polymorphism and mutation databases

BioMutaiZNF14
DMDMi313104250

Proteomic databases

EPDiP17017
jPOSTiP17017
MassIVEiP17017
MaxQBiP17017
PaxDbiP17017
PeptideAtlasiP17017
PRIDEiP17017
ProteomicsDBi53414

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
28563, 52 antibodies

Genome annotation databases

EnsembliENST00000344099; ENSP00000340514; ENSG00000105708
GeneIDi7561
KEGGihsa:7561
UCSCiuc002nnk.2, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
7561
DisGeNETi7561
EuPathDBiHostDB:ENSG00000105708.8

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZNF14
HGNCiHGNC:12924, ZNF14
HPAiENSG00000105708, Low tissue specificity
MIMi194556, gene
neXtProtiNX_P17017
OpenTargetsiENSG00000105708
PharmGKBiPA37511

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1721, Eukaryota
GeneTreeiENSGT00950000182755
HOGENOMiCLU_002678_44_3_1
InParanoidiP17017
KOiK09228
OMAiCHMVERL
OrthoDBi1318335at2759
PhylomeDBiP17017
TreeFamiTF343410

Enzyme and pathway databases

PathwayCommonsiP17017
ReactomeiR-HSA-212436, Generic Transcription Pathway

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
7561, 77 hits in 871 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
ZNF14, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
7561
PharosiP17017, Tdark

Protein Ontology

More...
PROi
PR:P17017
RNActiP17017, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000105708, Expressed in secondary oocyte and 219 other tissues
GenevisibleiP17017, HS

Family and domain databases

CDDicd07765, KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909, KRAB
IPR036051, KRAB_dom_sf
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF01352, KRAB, 1 hit
PF00096, zf-C2H2, 12 hits
SMARTiView protein in SMART
SM00349, KRAB, 1 hit
SM00355, ZnF_C2H2, 18 hits
SUPFAMiSSF109640, SSF109640, 1 hit
SSF57667, SSF57667, 11 hits
PROSITEiView protein in PROSITE
PS50805, KRAB, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 17 hits
PS50157, ZINC_FINGER_C2H2_2, 19 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZNF14_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P17017
Secondary accession number(s): B9EGA4, Q9ULZ5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1990
Last sequence update: November 30, 2010
Last modified: August 12, 2020
This is version 187 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families
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