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Entry version 149 (12 Aug 2020)
Sequence version 3 (15 Dec 1998)
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Protein

Protein RhsD

Gene

rhsD

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Rhs elements have a nonessential function. They may play an important role in the natural ecology of the cell.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
EcoCyc:EG10849-MONOMER
ECOL316407:JW0486-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein RhsD
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:rhsD
Ordered Locus Names:b0497, JW0486
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coli (strain K12)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri83333 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000318 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000222281 – 1426Protein RhsDAdd BLAST1426

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P16919

PRoteomics IDEntifications database

More...
PRIDEi
P16919

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Repressed by H-NS, induced by LeuO. Part of the rhsD-ybbC operon.1 Publication

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
4259865, 301 interactors

Database of interacting proteins

More...
DIPi
DIP-10702N

Protein interaction database and analysis system

More...
IntActi
P16919, 18 interactors

STRING: functional protein association networks

More...
STRINGi
511145.b0497

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P16919

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati334 – 35611 PublicationAdd BLAST23
Repeati357 – 37821 PublicationAdd BLAST22
Repeati379 – 42131 PublicationAdd BLAST43
Repeati422 – 44241 PublicationAdd BLAST21
Repeati443 – 46451 PublicationAdd BLAST22
Repeati465 – 48561 PublicationAdd BLAST21
Repeati486 – 50671 PublicationAdd BLAST21
Repeati507 – 52981 PublicationAdd BLAST23
Repeati530 – 55091 PublicationAdd BLAST21
Repeati551 – 571101 PublicationAdd BLAST21
Repeati572 – 592111 PublicationAdd BLAST21
Repeati593 – 613121 PublicationAdd BLAST21
Repeati614 – 633131 PublicationAdd BLAST20
Repeati634 – 654141 PublicationAdd BLAST21
Repeati655 – 675151 PublicationAdd BLAST21
Repeati676 – 695161 PublicationAdd BLAST20
Repeati696 – 715171 PublicationAdd BLAST20
Repeati716 – 738181 PublicationAdd BLAST23
Repeati739 – 762191 PublicationAdd BLAST24
Repeati812 – 832201 PublicationAdd BLAST21
Repeati833 – 861211 PublicationAdd BLAST29
Repeati862 – 882221 PublicationAdd BLAST21
Repeati883 – 905231 PublicationAdd BLAST23
Repeati906 – 941241 PublicationAdd BLAST36
Repeati942 – 970251 PublicationAdd BLAST29
Repeati971 – 995261 PublicationAdd BLAST25
Repeati996 – 1030271 PublicationAdd BLAST35
Repeati1173 – 1197281 PublicationAdd BLAST25

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni320 – 119728 X approximate tandem repeats1 PublicationAdd BLAST878

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Each rhs appears to consist of a highly conserved 141 kDa amino fragment followed by a highly divergent C-terminus.

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the RHS family.Curated

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
COG3209, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_001218_0_1_6

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P16919

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P16919

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR025479, DUF4329
IPR001826, RHS
IPR022385, Rhs_assc_core
IPR031325, RHS_repeat
IPR006530, YD

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF14220, DUF4329, 1 hit
PF03527, RHS, 1 hit
PF05593, RHS_repeat, 6 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00394, RHSPROTEIN

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR03696, Rhs_assc_core, 1 hit
TIGR01643, YD_repeat_2x, 7 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P16919-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSGKPAARQG DMTQYGGPIV QGSAGVRIGA PTGVACSVCP GGMTSGNPVN
60 70 80 90 100
PLLGAKVLPG ETDLALPGPL PFILSRTYSS YRTKTPAPVG VFGPGWKAPS
110 120 130 140 150
DIRLQLRDDG LILNDNGGRS IHFEPLLPGE AVYSRSESMW LVRGGKAAQP
160 170 180 190 200
DGHTLARLWG ALPPDIRLSP HLYLATNSAQ GPWWILGWSE RVPGAEDVLP
210 220 230 240 250
APLPPYRVLT GMADRFGRTL TYRREAAGDL AGEITGVTDG AGREFRLVLT
260 270 280 290 300
TQAQRAEEAR TSSLSSSDSS RPLSASAFPD TLPGTEYGPD RGIRLSAVWL
310 320 330 340 350
MHDPAYPESL PAAPLVRYTY TEAGELLAVY DRSNTQVRAF TYDAQHPGRM
360 370 380 390 400
VAHRYAGRPE MRYRYDDTGR VVEQLNPAGL SYRYLYEQDR ITVTDSLNRR
410 420 430 440 450
EVLHTEGGAG LKRVVKKELA DGSVTRSGYD AAGRLTAQTD AAGRRTEYGL
460 470 480 490 500
NVVSGDITDI TTPDGRETKF YYNDGNQLTA VVSPDGLESR REYDEPGRLV
510 520 530 540 550
SETSRSGETV RYRYDDAHSE LPATTTDATG STRQMTWSRY GQLLAFTDCS
560 570 580 590 600
GYQTRYEYDR FGQMTAVHRE EGISLYRRYD NRGRLTSVKD AQGRETRYEY
610 620 630 640 650
NAAGDLTAVI TPDGNRSETQ YDAWGKAVST TQGGLTRSME YDAAGRVISL
660 670 680 690 700
TNENGSHSVF SYDALDRLVQ QGGFDGRTQR YHYDLTGKLT QSEDEGLVIL
710 720 730 740 750
WYYDESDRIT HRTVNGEPAE QWQYDGHGWL TDISHLSEGH RVAVHYGYDD
760 770 780 790 800
KGRLTGECQT VENPETGELL WQHETKHAYN EQGLANRVTP DSLPPVEWLT
810 820 830 840 850
YGSGYLAGMK LGGTPLVEYT RDRLHRETVR SFGSMAGSNA AYELTSTYTP
860 870 880 890 900
AGQLQSQHLN SLVYDRDYGW SDNGDLVRIS GPRQTREYGY SATGRLESVR
910 920 930 940 950
TLAPDLDIRI PYATDPAGNR LPDPELHPDS TLTVWPDNRI AEDAHYVYRH
960 970 980 990 1000
DEYGRLTEKT DRIPAGVIRT DDERTHHYHY DSQHRLVFYT RIQHGEPLVE
1010 1020 1030 1040 1050
SRYLYDPLGR RMAKRVWRRE RDLTGWMSLS RKPEVTWYGW DGDRLTTVQT
1060 1070 1080 1090 1100
DTTRIQTVYE PGSFTPLIRV ETENGEREKA QRRSLAETLQ QEGSENGHGV
1110 1120 1130 1140 1150
VFPAELVRLL DRLEEEIRAD RVSSESRAWL AQCGLTVEQL ARQVEPEYTP
1160 1170 1180 1190 1200
ARKAHLYHCD HRGLPLALIS EDGNTAWSAE YDEWGNQLNE ENPHHVYQPY
1210 1220 1230 1240 1250
RLPGQQHDEE SGLYYNRHRY YDPLQGRYIT QDPMGLKGGW NLYQYPLNPL
1260 1270 1280 1290 1300
QQIDPMGLLQ TWDDARSGAC TGGVCGVLSR IIGPSKFDST ADAALDALKE
1310 1320 1330 1340 1350
TQNRSLCNDM EYSGIVCKDT NGKYFASKAE TDNLRKESYP LKRKCPTGTD
1360 1370 1380 1390 1400
RVAAYHTHGA DSHGDYVDEF FSSSDKNLVR SKDNNLEAFY LATPDGRFEA
1410 1420
LNNKGEYIFI RNSVPGLSSV CIPYHD
Length:1,426
Mass (Da):159,725
Last modified:December 15, 1998 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i122D697AA449BC2F
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X60999 Genomic DNA Translation: CAA43314.1
U82664 Genomic DNA Translation: AAB40251.1
U00096 Genomic DNA Translation: AAC73599.1
AP009048 Genomic DNA Translation: BAE76276.1
AF044500 Genomic DNA Translation: AAC32467.1

Protein sequence database of the Protein Information Resource

More...
PIRi
H64780

NCBI Reference Sequences

More...
RefSeqi
NP_415030.1, NC_000913.3
WP_000014739.1, NZ_CP047127.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AAC73599; AAC73599; b0497
BAE76276; BAE76276; BAE76276

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
945116

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ecj:JW0486
eco:b0497

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|1411691.4.peg.1779

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X60999 Genomic DNA Translation: CAA43314.1
U82664 Genomic DNA Translation: AAB40251.1
U00096 Genomic DNA Translation: AAC73599.1
AP009048 Genomic DNA Translation: BAE76276.1
AF044500 Genomic DNA Translation: AAC32467.1
PIRiH64780
RefSeqiNP_415030.1, NC_000913.3
WP_000014739.1, NZ_CP047127.1

3D structure databases

SMRiP16919
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi4259865, 301 interactors
DIPiDIP-10702N
IntActiP16919, 18 interactors
STRINGi511145.b0497

Proteomic databases

PaxDbiP16919
PRIDEiP16919

Genome annotation databases

EnsemblBacteriaiAAC73599; AAC73599; b0497
BAE76276; BAE76276; BAE76276
GeneIDi945116
KEGGiecj:JW0486
eco:b0497
PATRICifig|1411691.4.peg.1779

Organism-specific databases

EchoBASE - an integrated post-genomic database for E. coli

More...
EchoBASEi
EB0842

Phylogenomic databases

eggNOGiCOG3209, Bacteria
HOGENOMiCLU_001218_0_1_6
InParanoidiP16919
PhylomeDBiP16919

Enzyme and pathway databases

BioCyciEcoCyc:EG10849-MONOMER
ECOL316407:JW0486-MONOMER

Miscellaneous databases

Protein Ontology

More...
PROi
PR:P16919

Family and domain databases

InterProiView protein in InterPro
IPR025479, DUF4329
IPR001826, RHS
IPR022385, Rhs_assc_core
IPR031325, RHS_repeat
IPR006530, YD
PfamiView protein in Pfam
PF14220, DUF4329, 1 hit
PF03527, RHS, 1 hit
PF05593, RHS_repeat, 6 hits
PRINTSiPR00394, RHSPROTEIN
TIGRFAMsiTIGR03696, Rhs_assc_core, 1 hit
TIGR01643, YD_repeat_2x, 7 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRHSD_ECOLI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P16919
Secondary accession number(s): P77232, Q2MBT0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1990
Last sequence update: December 15, 1998
Last modified: August 12, 2020
This is version 149 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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