UniProtKB - P16685 (PHNG_ECOLI)
Protein
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG
Gene
phnG
Organism
Escherichia coli (strain K12)
Status
Functioni
Together with PhnH, PhnI and PhnL is required for the transfer of the ribose triphosphate moiety from ATP to methyl phosphonate.1 Publication
Miscellaneous
The sequence shown is that of strain K12.
Catalytic activityi
- EC:2.7.8.371 Publication
GO - Molecular functioni
- alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity Source: UniProtKB-EC
GO - Biological processi
- organic phosphonate catabolic process Source: EcoCyc
- organic phosphonate transport Source: InterPro
Keywordsi
Molecular function | Transferase |
Enzyme and pathway databases
BioCyci | EcoCyc:EG10716-MONOMER MetaCyc:EG10716-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG (EC:2.7.8.37)Short name: RPnTP synthase subunit PhnG |
Gene namesi | Name:phnG Ordered Locus Names:b4101, JW4062 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
GO - Cellular componenti
- alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase complex Source: EcoCyc
- carbon phosphorus lyase complex Source: EcoCyc
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000058391 | 1 – 150 | Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnGAdd BLAST | 150 |
Proteomic databases
jPOSTi | P16685 |
PaxDbi | P16685 |
PRIDEi | P16685 |
Interactioni
Subunit structurei
Forms a complex with PhnH, PhnI, PhnJ and PhnK with the suggested composition PhnG4H2I2J2K.
1 PublicationBinary interactionsi
Hide detailsProtein-protein interaction databases
BioGRIDi | 4263094, 3 interactors 852910, 1 interactor |
ComplexPortali | CPX-1929, PhnGHIJKL complex |
DIPi | DIP-10486N |
IntActi | P16685, 6 interactors |
STRINGi | 511145.b4101 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | P16685 |
ModBasei | Search... |
PDBe-KBi | Search... |
Family & Domainsi
Sequence similaritiesi
Belongs to the PhnG family.Curated
Phylogenomic databases
eggNOGi | COG3624, Bacteria |
HOGENOMi | CLU_109242_0_0_6 |
InParanoidi | P16685 |
PhylomeDBi | P16685 |
Family and domain databases
InterProi | View protein in InterPro IPR009609, Phosphonate_metab_PhnG |
Pfami | View protein in Pfam PF06754, PhnG, 1 hit |
TIGRFAMsi | TIGR03293, PhnG_redo, 1 hit |
i Sequence
Sequence statusi: Complete.
P16685-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MHADTATRQH WMSVLAHSQP AELAARLNAL NITADYEVIR AAETGLVQIQ
60 70 80 90 100
ARMGGTGERF FAGDATLTRA AVRLTDGTLG YSWVQGRDKQ HAERCALIDA
110 120 130 140 150
LMQQSRHFQN LSETLIAPLD ADRMARIAAR QAEVNASRVD FFTMVRGDNA
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural varianti | 85 | Q → L in strain: B. | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | J05260 Genomic DNA Translation: AAA24344.1 D90227 Genomic DNA Translation: BAA14267.1 U14003 Genomic DNA Translation: AAA97000.1 U00096 Genomic DNA Translation: AAC77062.1 AP009048 Genomic DNA Translation: BAE78104.1 |
PIRi | D65219 |
RefSeqi | NP_418525.1, NC_000913.3 WP_000542790.1, NZ_SSZK01000016.1 |
Genome annotation databases
EnsemblBacteriai | AAC77062; AAC77062; b4101 BAE78104; BAE78104; BAE78104 |
GeneIDi | 948618 |
KEGGi | ecj:JW4062 eco:b4101 |
PATRICi | fig|1411691.4.peg.2599 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | J05260 Genomic DNA Translation: AAA24344.1 D90227 Genomic DNA Translation: BAA14267.1 U14003 Genomic DNA Translation: AAA97000.1 U00096 Genomic DNA Translation: AAC77062.1 AP009048 Genomic DNA Translation: BAE78104.1 |
PIRi | D65219 |
RefSeqi | NP_418525.1, NC_000913.3 WP_000542790.1, NZ_SSZK01000016.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
4XB6 | X-ray | 1.70 | A/E | 1-150 | [»] | |
SMRi | P16685 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 4263094, 3 interactors 852910, 1 interactor |
ComplexPortali | CPX-1929, PhnGHIJKL complex |
DIPi | DIP-10486N |
IntActi | P16685, 6 interactors |
STRINGi | 511145.b4101 |
Proteomic databases
jPOSTi | P16685 |
PaxDbi | P16685 |
PRIDEi | P16685 |
Genome annotation databases
EnsemblBacteriai | AAC77062; AAC77062; b4101 BAE78104; BAE78104; BAE78104 |
GeneIDi | 948618 |
KEGGi | ecj:JW4062 eco:b4101 |
PATRICi | fig|1411691.4.peg.2599 |
Organism-specific databases
EchoBASEi | EB0710 |
Phylogenomic databases
eggNOGi | COG3624, Bacteria |
HOGENOMi | CLU_109242_0_0_6 |
InParanoidi | P16685 |
PhylomeDBi | P16685 |
Enzyme and pathway databases
BioCyci | EcoCyc:EG10716-MONOMER MetaCyc:EG10716-MONOMER |
Miscellaneous databases
PROi | PR:P16685 |
Family and domain databases
InterProi | View protein in InterPro IPR009609, Phosphonate_metab_PhnG |
Pfami | View protein in Pfam PF06754, PhnG, 1 hit |
TIGRFAMsi | TIGR03293, PhnG_redo, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | PHNG_ECOLI | |
Accessioni | P16685Primary (citable) accession number: P16685 Secondary accession number(s): Q2M6K2 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | August 1, 1990 |
Last sequence update: | November 1, 1991 | |
Last modified: | December 2, 2020 | |
This is version 135 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families