UniProtKB - P16679 (PHNL_ECOLI)
Protein
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL
Gene
phnL
Organism
Escherichia coli (strain K12)
Status
Functioni
Together with PhnG, PhnH and PhnI is required for the transfer of the ribose triphosphate moiety from ATP to methyl phosphonate.1 Publication
Catalytic activityi
- EC:2.7.8.371 Publication
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 41 – 48 | ATPPROSITE-ProRule annotation | 8 |
GO - Molecular functioni
- alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity Source: UniProtKB-EC
- ATPase activity Source: InterPro
- ATP binding Source: UniProtKB-KW
GO - Biological processi
- organic phosphonate catabolic process Source: EcoCyc
Keywordsi
Molecular function | Transferase |
Ligand | ATP-binding, Nucleotide-binding |
Enzyme and pathway databases
BioCyci | EcoCyc:PHNL-MONOMER MetaCyc:PHNL-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL (EC:2.7.8.37)Short name: RPnTP synthase subunit PhnL |
Gene namesi | Name:phnL Ordered Locus Names:b4096, JW4057 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
GO - Cellular componenti
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000092745 | 1 – 226 | Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnLAdd BLAST | 226 |
Proteomic databases
PaxDbi | P16679 |
PRIDEi | P16679 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4262019, 4 interactors 852905, 1 interactor |
ComplexPortali | CPX-1929, PhnGHIJKL complex |
IntActi | P16679, 4 interactors |
STRINGi | 511145.b4096 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 2 – 226 | ABC transporterPROSITE-ProRule annotationAdd BLAST | 225 |
Sequence similaritiesi
Belongs to the ABC transporter superfamily.Curated
Phylogenomic databases
eggNOGi | COG4778, Bacteria |
HOGENOMi | CLU_000604_1_22_6 |
InParanoidi | P16679 |
PhylomeDBi | P16679 |
Family and domain databases
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR003439, ABC_transporter-like IPR017871, ABC_transporter_CS IPR012701, CP_lyase_PhnL IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00005, ABC_tran, 1 hit |
SMARTi | View protein in SMART SM00382, AAA, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
TIGRFAMsi | TIGR02324, CP_lyasePhnL, 1 hit |
PROSITEi | View protein in PROSITE PS00211, ABC_TRANSPORTER_1, 1 hit PS50893, ABC_TRANSPORTER_2, 1 hit |
i Sequence
Sequence statusi: Complete.
P16679-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MINVQNVSKT FILHQQNGVR LPVLNRASLT VNAGECVVLH GHSGSGKSTL
60 70 80 90 100
LRSLYANYLP DEGQIQIKHG DEWVDLVTAP ARKVVEIRKT TVGWVSQFLR
110 120 130 140 150
VIPRISALEV VMQPLLDTGV PREACAAKAA RLLTRLNVPE RLWHLAPSTF
160 170 180 190 200
SGGEQQRVNI ARGFIVDYPI LLLDEPTASL DAKNSAAVVE LIREAKTRGA
210 220
AIVGIFHDEA VRNDVADRLH PMGASS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | J05260 Genomic DNA Translation: AAA24350.1 D90227 Genomic DNA Translation: BAA14272.1 U14003 Genomic DNA Translation: AAA96995.1 U00096 Genomic DNA Translation: AAC77057.1 AP009048 Genomic DNA Translation: BAE78099.1 |
PIRi | D35719 |
RefSeqi | NP_418520.1, NC_000913.3 WP_000611405.1, NZ_SSZK01000016.1 |
Genome annotation databases
EnsemblBacteriai | AAC77057; AAC77057; b4096 BAE78099; BAE78099; BAE78099 |
GeneIDi | 948612 |
KEGGi | ecj:JW4057 eco:b4096 |
PATRICi | fig|1411691.4.peg.2604 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | J05260 Genomic DNA Translation: AAA24350.1 D90227 Genomic DNA Translation: BAA14272.1 U14003 Genomic DNA Translation: AAA96995.1 U00096 Genomic DNA Translation: AAC77057.1 AP009048 Genomic DNA Translation: BAE78099.1 |
PIRi | D35719 |
RefSeqi | NP_418520.1, NC_000913.3 WP_000611405.1, NZ_SSZK01000016.1 |
3D structure databases
SMRi | P16679 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 4262019, 4 interactors 852905, 1 interactor |
ComplexPortali | CPX-1929, PhnGHIJKL complex |
IntActi | P16679, 4 interactors |
STRINGi | 511145.b4096 |
Proteomic databases
PaxDbi | P16679 |
PRIDEi | P16679 |
Genome annotation databases
EnsemblBacteriai | AAC77057; AAC77057; b4096 BAE78099; BAE78099; BAE78099 |
GeneIDi | 948612 |
KEGGi | ecj:JW4057 eco:b4096 |
PATRICi | fig|1411691.4.peg.2604 |
Organism-specific databases
EchoBASEi | EB0715 |
Phylogenomic databases
eggNOGi | COG4778, Bacteria |
HOGENOMi | CLU_000604_1_22_6 |
InParanoidi | P16679 |
PhylomeDBi | P16679 |
Enzyme and pathway databases
BioCyci | EcoCyc:PHNL-MONOMER MetaCyc:PHNL-MONOMER |
Miscellaneous databases
PROi | PR:P16679 |
Family and domain databases
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR003439, ABC_transporter-like IPR017871, ABC_transporter_CS IPR012701, CP_lyase_PhnL IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00005, ABC_tran, 1 hit |
SMARTi | View protein in SMART SM00382, AAA, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
TIGRFAMsi | TIGR02324, CP_lyasePhnL, 1 hit |
PROSITEi | View protein in PROSITE PS00211, ABC_TRANSPORTER_1, 1 hit PS50893, ABC_TRANSPORTER_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | PHNL_ECOLI | |
Accessioni | P16679Primary (citable) accession number: P16679 Secondary accession number(s): Q2M6K7 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | August 1, 1990 |
Last sequence update: | August 1, 1990 | |
Last modified: | December 2, 2020 | |
This is version 153 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families