UniProtKB - P16113 (PYP_HALHA)
Protein
Photoactive yellow protein
Gene
pyp
Organism
Halorhodospira halophila (Ectothiorhodospira halophila)
Status
Functioni
Photoactive blue light protein. Probably functions as a photoreceptor for a negative phototaxis response.
GO - Molecular functioni
- identical protein binding Source: IntAct
- photoreceptor activity Source: UniProtKB-KW
GO - Biological processi
- phototransduction Source: InterPro
- protein-chromophore linkage Source: UniProtKB-KW
- regulation of transcription, DNA-templated Source: InterPro
Keywordsi
Molecular function | Photoreceptor protein, Receptor |
Biological process | Sensory transduction |
Ligand | Chromophore |
Names & Taxonomyi
Protein namesi | Recommended name: Photoactive yellow proteinShort name: PYP |
Gene namesi | Name:pyp |
Organismi | Halorhodospira halophila (Ectothiorhodospira halophila) |
Taxonomic identifieri | 1053 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Chromatiales › Ectothiorhodospiraceae › Halorhodospira |
Pathology & Biotechi
Chemistry databases
DrugBanki | DB01880, 3,4-Dihydroxycinnamic Acid DB04066, p-Coumaric acid |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000144914 | 1 – 125 | Photoactive yellow proteinAdd BLAST | 125 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 69 | S-(4-hydroxycinnamyl)cysteine1 Publication | 1 |
Post-translational modificationi
The 4-hydroxycinnamic acid (p-coumaric acid) chromophore is covalently bound via a thioester linkage.
Interactioni
Subunit structurei
Monomer.
Binary interactionsi
P16113
With | #Exp. | IntAct |
---|---|---|
itself | 4 | EBI-15592191,EBI-15592191 |
GO - Molecular functioni
- identical protein binding Source: IntAct
Protein-protein interaction databases
DIPi | DIP-61234N |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
BMRBi | P16113 |
SMRi | P16113 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P16113 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 23 – 86 | PASPROSITE-ProRule annotationAdd BLAST | 64 |
Sequence similaritiesi
Belongs to the photoactive yellow protein family.Curated
Family and domain databases
CDDi | cd00130, PAS, 1 hit |
InterProi | View protein in InterPro IPR000014, PAS IPR035965, PAS-like_dom_sf IPR013767, PAS_fold IPR012130, PYP |
Pfami | View protein in Pfam PF00989, PAS, 1 hit |
PIRSFi | PIRSF000087, PYP, 1 hit |
SMARTi | View protein in SMART SM00091, PAS, 1 hit |
SUPFAMi | SSF55785, SSF55785, 1 hit |
TIGRFAMsi | TIGR02373, photo_yellow, 1 hit |
PROSITEi | View protein in PROSITE PS50112, PAS, 1 hit |
i Sequence
Sequence statusi: Complete.
P16113-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEHVAFGSED IENTLAKMDD GQLDGLAFGA IQLDGDGNIL QYNAAEGDIT
60 70 80 90 100
GRDPKQVIGK NFFKDVAPCT DSPEFYGKFK EGVASGNLNT MFEYTFDYQM
110 120
TPTKVKVHMK KALSGDSYWV FVKRV
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 56 | Q → E AA sequence (PubMed:8358295).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U17017 Genomic DNA Translation: AAA61735.1 X98887 Genomic DNA Translation: CAA67391.1 |
PIRi | B55993, JC5446 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U17017 Genomic DNA Translation: AAA61735.1 X98887 Genomic DNA Translation: CAA67391.1 |
PIRi | B55993, JC5446 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1D7E | X-ray | 1.39 | A | 4-125 | [»] | |
1F98 | X-ray | 1.15 | A | 1-125 | [»] | |
1F9I | X-ray | 1.10 | A | 1-125 | [»] | |
1GSV | X-ray | 1.75 | A | 1-125 | [»] | |
1GSW | X-ray | 1.85 | A | 1-125 | [»] | |
1GSX | X-ray | 1.79 | A | 1-125 | [»] | |
1KOU | X-ray | 1.16 | A | 1-125 | [»] | |
1NWZ | X-ray | 0.82 | A | 1-125 | [»] | |
1ODV | X-ray | 1.14 | A/B | 26-125 | [»] | |
1OT6 | X-ray | 0.95 | A | 1-125 | [»] | |
1OT9 | X-ray | 1.00 | A | 1-125 | [»] | |
1OTA | X-ray | 1.10 | A | 1-125 | [»] | |
1OTB | X-ray | 1.10 | A | 1-125 | [»] | |
1OTD | X-ray | 1.25 | A/B | 1-125 | [»] | |
1OTE | X-ray | 1.40 | A | 1-125 | [»] | |
1OTI | X-ray | 1.40 | A | 1-125 | [»] | |
1S1Y | X-ray | 1.60 | A | 1-125 | [»] | |
1S1Z | X-ray | 1.60 | A | 1-125 | [»] | |
1S4R | X-ray | 1.90 | A | 1-125 | [»] | |
1S4S | X-ray | 1.90 | A | 1-125 | [»] | |
1T18 | X-ray | 1.60 | A | 1-125 | [»] | |
1T19 | X-ray | 1.60 | A | 1-125 | [»] | |
1T1A | X-ray | 1.60 | A | 1-125 | [»] | |
1T1B | X-ray | 1.60 | A | 1-125 | [»] | |
1T1C | X-ray | 1.60 | A | 1-125 | [»] | |
1TS0 | X-ray | 1.60 | A | 1-125 | [»] | |
1TS6 | X-ray | 1.60 | A | 1-125 | [»] | |
1TS7 | X-ray | 1.60 | A | 1-125 | [»] | |
1TS8 | X-ray | 1.60 | A | 1-125 | [»] | |
1UGU | X-ray | 1.20 | A | 1-125 | [»] | |
1UWN | X-ray | 1.20 | X | 1-125 | [»] | |
1UWP | X-ray | 1.20 | X | 1-125 | [»] | |
1XFN | NMR | - | A | 26-125 | [»] | |
1XFQ | NMR | - | A | 26-125 | [»] | |
2D01 | X-ray | 1.34 | A | 1-125 | [»] | |
2D02 | X-ray | 1.42 | A | 1-125 | [»] | |
2I9V | X-ray | 2.20 | A | 1-125 | [»] | |
2KX6 | Other | - | A | 1-125 | [»] | |
2PHY | X-ray | 1.40 | A | 1-125 | [»] | |
2PYP | X-ray | 1.90 | A | 1-125 | [»] | |
2PYR | X-ray | 1.90 | A | 1-125 | [»] | |
2QJ5 | X-ray | 1.20 | A | 1-125 | [»] | |
2QJ7 | X-ray | 1.05 | A | 1-125 | [»] | |
2QWS | X-ray | 2.50 | A | 1-125 | [»] | |
2ZOH | X-ray | 1.25 | A | 1-125 | [»] | |
2ZOI | neutron diffraction | 1.50 | A | 1-125 | [»] | |
3PHY | NMR | - | A | 1-125 | [»] | |
3PYP | X-ray | 0.85 | A | 1-125 | [»] | |
3UMD | X-ray | 1.80 | A | 1-125 | [»] | |
3UME | X-ray | 1.80 | A | 1-125 | [»] | |
3VE3 | X-ray | 1.60 | A | 1-125 | [»] | |
3VE4 | X-ray | 1.60 | A | 1-125 | [»] | |
4B9O | X-ray | 1.60 | A | 1-125 | [»] | |
4BBT | X-ray | 1.60 | A | 1-125 | [»] | |
4BBU | X-ray | 1.60 | A | 1-125 | [»] | |
4BBV | X-ray | 1.60 | A | 1-125 | [»] | |
4HY8 | X-ray | 1.60 | A | 1-125 | [»] | |
4I38 | X-ray | 1.60 | A | 1-125 | [»] | |
4I39 | X-ray | 1.60 | A | 1-125 | [»] | |
4I3A | X-ray | 1.60 | A | 1-125 | [»] | |
4I3I | X-ray | 1.60 | A | 1-125 | [»] | |
4I3J | X-ray | 1.60 | A | 1-125 | [»] | |
4WL9 | X-ray | 1.60 | A | 1-125 | [»] | |
4WLA | X-ray | 1.60 | A | 1-125 | [»] | |
5GX9 | neutron diffraction | 1.49 | A | 1-125 | [»] | |
5HD3 | X-ray | 1.60 | A | 1-125 | [»] | |
5HD5 | X-ray | 1.60 | A | 1-125 | [»] | |
5HDC | X-ray | 1.60 | A | 1-125 | [»] | |
5HDD | X-ray | 1.60 | A | 1-125 | [»] | |
5HDS | X-ray | 1.60 | A | 1-125 | [»] | |
6MHI | X-ray | 1.35 | A | 1-125 | [»] | |
6MHN | X-ray | 1.67 | A | 1-125 | [»] | |
6MKT | X-ray | 1.60 | A | 1-125 | [»] | |
6MMD | X-ray | 1.23 | A/B | 1-125 | [»] | |
6P4I | X-ray | 1.60 | A | 1-125 | [»] | |
6P5D | X-ray | 1.60 | A | 1-125 | [»] | |
6P5E | X-ray | 1.60 | A | 1-125 | [»] | |
6P5F | X-ray | 1.70 | A | 1-125 | [»] | |
6P5G | X-ray | 1.60 | A | 1-125 | [»] | |
6UMY | X-ray | 0.92 | A | 1-125 | [»] | |
6UMZ | X-ray | 0.90 | A | 1-125 | [»] | |
6UN0 | X-ray | 0.85 | A | 1-125 | [»] | |
6UN2 | X-ray | 0.97 | A | 1-125 | [»] | |
BMRBi | P16113 | |||||
SMRi | P16113 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
DIPi | DIP-61234N |
Chemistry databases
DrugBanki | DB01880, 3,4-Dihydroxycinnamic Acid DB04066, p-Coumaric acid |
Miscellaneous databases
EvolutionaryTracei | P16113 |
Family and domain databases
CDDi | cd00130, PAS, 1 hit |
InterProi | View protein in InterPro IPR000014, PAS IPR035965, PAS-like_dom_sf IPR013767, PAS_fold IPR012130, PYP |
Pfami | View protein in Pfam PF00989, PAS, 1 hit |
PIRSFi | PIRSF000087, PYP, 1 hit |
SMARTi | View protein in SMART SM00091, PAS, 1 hit |
SUPFAMi | SSF55785, SSF55785, 1 hit |
TIGRFAMsi | TIGR02373, photo_yellow, 1 hit |
PROSITEi | View protein in PROSITE PS50112, PAS, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | PYP_HALHA | |
Accessioni | P16113Primary (citable) accession number: P16113 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 1, 1990 |
Last sequence update: | November 1, 1995 | |
Last modified: | October 7, 2020 | |
This is version 122 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencingDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families