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Protein

P-selectin

Gene

SELP

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Ca2+-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with SELPLG.3 Publications

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi121CalciumCombined sources1 Publication1
Metal bindingi123CalciumCombined sources1 Publication1
Binding sitei123CarbohydrateCombined sources1 Publication1
Metal bindingi124CalciumCombined sources1
Binding sitei133CarbohydrateCombined sources1 Publication1
Metal bindingi146CalciumCombined sources1 Publication1
Binding sitei146CarbohydrateCombined sources1 Publication1
Metal bindingi147CalciumCombined sources1 Publication1

GO - Molecular functioni

  • calcium-dependent protein binding Source: Ensembl
  • calcium ion binding Source: UniProtKB
  • fucose binding Source: BHF-UCL
  • glycosphingolipid binding Source: BHF-UCL
  • heparin binding Source: BHF-UCL
  • lipopolysaccharide binding Source: BHF-UCL
  • oligosaccharide binding Source: UniProtKB
  • sialic acid binding Source: BHF-UCL

GO - Biological processi

Keywordsi

Biological processCell adhesion
LigandCalcium, Lectin, Metal-binding

Enzyme and pathway databases

ReactomeiR-HSA-114608 Platelet degranulation
R-HSA-202733 Cell surface interactions at the vascular wall
SIGNORiP16109

Protein family/group databases

UniLectiniP16109

Names & Taxonomyi

Protein namesi
Recommended name:
P-selectin
Alternative name(s):
CD62 antigen-like family member P
Granule membrane protein 140
Short name:
GMP-1401 Publication
Leukocyte-endothelial cell adhesion molecule 3
Short name:
LECAM3
Platelet activation dependent granule-external membrane protein
Short name:
PADGEM
CD_antigen: CD62P
Gene namesi
Name:SELP
Synonyms:GMRP, GRMP
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000174175.16
HGNCiHGNC:10721 SELP
MIMi173610 gene+phenotype
neXtProtiNX_P16109

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini42 – 771ExtracellularSequence analysisAdd BLAST730
Transmembranei772 – 795HelicalSequence analysisAdd BLAST24
Topological domaini796 – 830CytoplasmicSequence analysisAdd BLAST35

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Involvement in diseasei

Ischemic stroke (ISCHSTR)1 Publication
Disease susceptibility is associated with variations affecting the gene represented in this entry.
Disease descriptionA stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors.
See also OMIM:601367

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Mutagenesisi129E → D: Impairs interaction with SELPLG. Abolishes cell rolling on glycan ligands. 1 Publication1

Organism-specific databases

DisGeNETi6403
MalaCardsiSELP
MIMi173610 gene+phenotype
601367 phenotype
PharmGKBiPA35643

Chemistry databases

ChEMBLiCHEMBL5378
DrugBankiDB06779 Dalteparin
DB01109 Heparin
DB03721 N-acetyl-alpha-neuraminic acid
DB08813 Nadroparin

Polymorphism and mutation databases

BioMutaiSELP
DMDMi215274139

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 41Add BLAST41
ChainiPRO_000001749842 – 830P-selectinAdd BLAST789

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi54N-linked (GlcNAc...) asparagine1 Publication1
Disulfide bondi60 ↔ 158Combined sources1 Publication
Glycosylationi98N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi131 ↔ 150Combined sources1 Publication
Disulfide bondi163 ↔ 174Combined sources1 Publication
Disulfide bondi168 ↔ 183Combined sources1 Publication
Glycosylationi180N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi185 ↔ 194Combined sources1 Publication
Disulfide bondi200 ↔ 244By similarity
Glycosylationi212N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi219N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi230 ↔ 257By similarity
Disulfide bondi262 ↔ 306By similarity
Disulfide bondi292 ↔ 319By similarity
Disulfide bondi324 ↔ 368By similarity
Disulfide bondi354 ↔ 381By similarity
Disulfide bondi386 ↔ 430By similarity
Glycosylationi411N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi416 ↔ 443By similarity
Disulfide bondi448 ↔ 492By similarity
Glycosylationi460N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi478 ↔ 505By similarity
Disulfide bondi510 ↔ 554By similarity
Glycosylationi518N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi540 ↔ 567By similarity
Disulfide bondi572 ↔ 616By similarity
Disulfide bondi602 ↔ 629By similarity
Disulfide bondi642 ↔ 686By similarity
Glycosylationi665N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi672 ↔ 699By similarity
Disulfide bondi704 ↔ 748By similarity
Glycosylationi716N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi723N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi734 ↔ 761By similarity
Glycosylationi741N-linked (GlcNAc...) asparagineSequence analysis1
Lipidationi807S-palmitoyl cysteine; alternate1 Publication1
Lipidationi807S-stearoyl cysteine; alternate1 Publication1

Keywords - PTMi

Disulfide bond, Glycoprotein, Lipoprotein, Palmitate

Proteomic databases

PaxDbiP16109
PeptideAtlasiP16109
PRIDEiP16109
ProteomicsDBi53287

PTM databases

iPTMnetiP16109
PhosphoSitePlusiP16109
SwissPalmiP16109

Expressioni

Tissue specificityi

Stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.

Gene expression databases

BgeeiENSG00000174175 Expressed in 136 organ(s), highest expression level in adrenal gland
CleanExiHS_SELP
ExpressionAtlasiP16109 baseline and differential
GenevisibleiP16109 HS

Organism-specific databases

HPAiCAB002145
HPA002655
HPA005990

Interactioni

Subunit structurei

Interacts with SNX17. Interacts with SELPLG/PSGL1 and PODXL2 and mediates neutrophil adhesion and leukocyte rolling. This interaction requires the sialyl-Lewis X epitope of SELPLG and PODXL2, and specific tyrosine sulfation on SELPLG.7 Publications

Binary interactionsi

WithEntry#Exp.IntActNotes
SELPLGQ142424EBI-1030170,EBI-1030190

GO - Molecular functioni

Protein-protein interaction databases

BioGridi112303, 9 interactors
DIPiDIP-37667N
ELMiP16109
IntActiP16109, 2 interactors
STRINGi9606.ENSP00000263686

Chemistry databases

BindingDBiP16109

Structurei

Secondary structure

1830
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliP16109
SMRiP16109
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP16109

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini58 – 158C-type lectinPROSITE-ProRule annotationAdd BLAST101
Domaini159 – 195EGF-likePROSITE-ProRule annotationAdd BLAST37
Domaini198 – 259Sushi 1PROSITE-ProRule annotationAdd BLAST62
Domaini260 – 321Sushi 2PROSITE-ProRule annotationAdd BLAST62
Domaini322 – 383Sushi 3PROSITE-ProRule annotationAdd BLAST62
Domaini384 – 445Sushi 4PROSITE-ProRule annotationAdd BLAST62
Domaini446 – 507Sushi 5PROSITE-ProRule annotationAdd BLAST62
Domaini508 – 569Sushi 6PROSITE-ProRule annotationAdd BLAST62
Domaini570 – 631Sushi 7PROSITE-ProRule annotationAdd BLAST62
Domaini640 – 701Sushi 8PROSITE-ProRule annotationAdd BLAST62
Domaini702 – 763Sushi 9PROSITE-ProRule annotationAdd BLAST62

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni821 – 830Interaction with SNX1710

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi818 – 821Endocytosis signalCurated4

Sequence similaritiesi

Belongs to the selectin/LECAM family.Curated

Keywords - Domaini

EGF-like domain, Repeat, Signal, Sushi, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IS44 Eukaryota
ENOG410Y5JF LUCA
HOGENOMiHOG000236254
HOVERGENiHBG052375
InParanoidiP16109
KOiK06496
OrthoDBiEOG091G00VV
PhylomeDBiP16109
TreeFamiTF326910

Family and domain databases

CDDicd00033 CCP, 9 hits
cd03592 CLECT_selectins_like, 1 hit
Gene3Di3.10.100.10, 1 hit
InterProiView protein in InterPro
IPR001304 C-type_lectin-like
IPR016186 C-type_lectin-like/link_sf
IPR018378 C-type_lectin_CS
IPR016187 CTDL_fold
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR033991 Selectin_CTLD
IPR002396 Selectin_superfamily
IPR035976 Sushi/SCR/CCP_sf
IPR000436 Sushi_SCR_CCP_dom
PfamiView protein in Pfam
PF00059 Lectin_C, 1 hit
PF00084 Sushi, 9 hits
PRINTSiPR00343 SELECTIN
SMARTiView protein in SMART
SM00032 CCP, 9 hits
SM00034 CLECT, 1 hit
SUPFAMiSSF56436 SSF56436, 1 hit
SSF57535 SSF57535, 9 hits
PROSITEiView protein in PROSITE
PS00615 C_TYPE_LECTIN_1, 1 hit
PS50041 C_TYPE_LECTIN_2, 1 hit
PS00022 EGF_1, 1 hit
PS01186 EGF_2, 1 hit
PS50026 EGF_3, 1 hit
PS50923 SUSHI, 9 hits

Sequence (1+)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

P16109-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MANCQIAILY QRFQRVVFGI SQLLCFSALI SELTNQKEVA AWTYHYSTKA
60 70 80 90 100
YSWNISRKYC QNRYTDLVAI QNKNEIDYLN KVLPYYSSYY WIGIRKNNKT
110 120 130 140 150
WTWVGTKKAL TNEAENWADN EPNNKRNNED CVEIYIKSPS APGKWNDEHC
160 170 180 190 200
LKKKHALCYT ASCQDMSCSK QGECLETIGN YTCSCYPGFY GPECEYVREC
210 220 230 240 250
GELELPQHVL MNCSHPLGNF SFNSQCSFHC TDGYQVNGPS KLECLASGIW
260 270 280 290 300
TNKPPQCLAA QCPPLKIPER GNMTCLHSAK AFQHQSSCSF SCEEGFALVG
310 320 330 340 350
PEVVQCTASG VWTAPAPVCK AVQCQHLEAP SEGTMDCVHP LTAFAYGSSC
360 370 380 390 400
KFECQPGYRV RGLDMLRCID SGHWSAPLPT CEAISCEPLE SPVHGSMDCS
410 420 430 440 450
PSLRAFQYDT NCSFRCAEGF MLRGADIVRC DNLGQWTAPA PVCQALQCQD
460 470 480 490 500
LPVPNEARVN CSHPFGAFRY QSVCSFTCNE GLLLVGASVL QCLATGNWNS
510 520 530 540 550
VPPECQAIPC TPLLSPQNGT MTCVQPLGSS SYKSTCQFIC DEGYSLSGPE
560 570 580 590 600
RLDCTRSGRW TDSPPMCEAI KCPELFAPEQ GSLDCSDTRG EFNVGSTCHF
610 620 630 640 650
SCDNGFKLEG PNNVECTTSG RWSATPPTCK GIASLPTPGL QCPALTTPGQ
660 670 680 690 700
GTMYCRHHPG TFGFNTTCYF GCNAGFTLIG DSTLSCRPSG QWTAVTPACR
710 720 730 740 750
AVKCSELHVN KPIAMNCSNL WGNFSYGSIC SFHCLEGQLL NGSAQTACQE
760 770 780 790 800
NGHWSTTVPT CQAGPLTIQE ALTYFGGAVA STIGLIMGGT LLALLRKRFR
810 820 830
QKDDGKCPLN PHSHLGTYGV FTNAAFDPSP
Length:830
Mass (Da):90,834
Last modified:November 25, 2008 - v3
Checksum:iF53BC476AB6F70AC
GO

Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q5R341Q5R341_HUMAN
P-selectin
SELP hCG_38007
768Annotation score:
Q5R342Q5R342_HUMAN
P-selectin
SELP
646Annotation score:
Q5R345Q5R345_HUMAN
P-selectin
SELP
768Annotation score:
Q5R349Q5R349_HUMAN
P-selectin
SELP
789Annotation score:
F6VVT6F6VVT6_HUMAN
P-selectin
SELP
444Annotation score:

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_019381179G → R1 PublicationCorresponds to variant dbSNP:rs3917718Ensembl.1
Natural variantiVAR_013910209V → M2 PublicationsCorresponds to variant dbSNP:rs6125Ensembl.1
Natural variantiVAR_019382230C → F1 PublicationCorresponds to variant dbSNP:rs3917869Ensembl.1
Natural variantiVAR_019383274T → I2 PublicationsCorresponds to variant dbSNP:rs3917724Ensembl.1
Natural variantiVAR_013911301P → L1 PublicationCorresponds to variant dbSNP:rs6124Ensembl.1
Natural variantiVAR_004192331S → N3 PublicationsCorresponds to variant dbSNP:rs6131Ensembl.1
Natural variantiVAR_013912365M → V1 PublicationCorresponds to variant dbSNP:rs6134Ensembl.1
Natural variantiVAR_019384385S → L1 PublicationCorresponds to variant dbSNP:rs3917742Ensembl.1
Natural variantiVAR_013913500S → F1 PublicationCorresponds to variant dbSNP:rs6130Ensembl.1
Natural variantiVAR_019385542E → K1 PublicationCorresponds to variant dbSNP:rs3917769Ensembl.1
Natural variantiVAR_004193603D → N4 PublicationsCorresponds to variant dbSNP:rs6127Ensembl.1
Natural variantiVAR_019386619S → A1 PublicationCorresponds to variant dbSNP:rs2228672Ensembl.1
Natural variantiVAR_019387631G → V1 PublicationCorresponds to variant dbSNP:rs3917812Ensembl.1
Natural variantiVAR_004194640L → V Associated with susceptibility to ischemic stroke. 5 PublicationsCorresponds to variant dbSNP:rs6133Ensembl.1
Natural variantiVAR_019388661T → N1 PublicationCorresponds to variant dbSNP:rs3917814Ensembl.1
Natural variantiVAR_019389673N → S1 PublicationCorresponds to variant dbSNP:rs3917815Ensembl.1
Natural variantiVAR_004195756T → P Reduced frequency in patients with myocardial infarction. 3 PublicationsCorresponds to variant dbSNP:rs6136EnsemblClinVar.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M60234
, M60217, M60218, M60219, M60222, M60223, M60224, M60225, M60226, M60227, M60228, M60229, M60231, M60232, M60233 Genomic DNA Translation: AAA35910.1
M25322 mRNA Translation: AAA35911.1
AF542391 Genomic DNA Translation: AAN06828.1
AL022146 Genomic DNA No translation available.
Z99572 Genomic DNA No translation available.
CH471067 Genomic DNA Translation: EAW90851.1
CCDSiCCDS1282.1
PIRiA30359
RefSeqiNP_002996.2, NM_003005.3
XP_005245492.1, XM_005245435.1
XP_005245493.1, XM_005245436.3
UniGeneiHs.73800

Genome annotation databases

EnsembliENST00000263686; ENSP00000263686; ENSG00000174175
GeneIDi6403
KEGGihsa:6403
UCSCiuc001ggi.5 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Cross-referencesi

Web resourcesi

SeattleSNPs
Functional Glycomics Gateway - Glycan Binding

P-selectin

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M60234
, M60217, M60218, M60219, M60222, M60223, M60224, M60225, M60226, M60227, M60228, M60229, M60231, M60232, M60233 Genomic DNA Translation: AAA35910.1
M25322 mRNA Translation: AAA35911.1
AF542391 Genomic DNA Translation: AAN06828.1
AL022146 Genomic DNA No translation available.
Z99572 Genomic DNA No translation available.
CH471067 Genomic DNA Translation: EAW90851.1
CCDSiCCDS1282.1
PIRiA30359
RefSeqiNP_002996.2, NM_003005.3
XP_005245492.1, XM_005245435.1
XP_005245493.1, XM_005245436.3
UniGeneiHs.73800

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1FSBNMR-A160-199[»]
1G1QX-ray2.40A/B/C/D42-198[»]
1G1RX-ray3.40A/B/C/D42-198[»]
1G1SX-ray1.90A/B42-198[»]
1HESX-ray3.00P813-830[»]
1KJDmodel-A42-161[»]
ProteinModelPortaliP16109
SMRiP16109
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi112303, 9 interactors
DIPiDIP-37667N
ELMiP16109
IntActiP16109, 2 interactors
STRINGi9606.ENSP00000263686

Chemistry databases

BindingDBiP16109
ChEMBLiCHEMBL5378
DrugBankiDB06779 Dalteparin
DB01109 Heparin
DB03721 N-acetyl-alpha-neuraminic acid
DB08813 Nadroparin

Protein family/group databases

UniLectiniP16109

PTM databases

iPTMnetiP16109
PhosphoSitePlusiP16109
SwissPalmiP16109

Polymorphism and mutation databases

BioMutaiSELP
DMDMi215274139

Proteomic databases

PaxDbiP16109
PeptideAtlasiP16109
PRIDEiP16109
ProteomicsDBi53287

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000263686; ENSP00000263686; ENSG00000174175
GeneIDi6403
KEGGihsa:6403
UCSCiuc001ggi.5 human

Organism-specific databases

CTDi6403
DisGeNETi6403
EuPathDBiHostDB:ENSG00000174175.16
GeneCardsiSELP
HGNCiHGNC:10721 SELP
HPAiCAB002145
HPA002655
HPA005990
MalaCardsiSELP
MIMi173610 gene+phenotype
601367 phenotype
neXtProtiNX_P16109
PharmGKBiPA35643
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IS44 Eukaryota
ENOG410Y5JF LUCA
HOGENOMiHOG000236254
HOVERGENiHBG052375
InParanoidiP16109
KOiK06496
OrthoDBiEOG091G00VV
PhylomeDBiP16109
TreeFamiTF326910

Enzyme and pathway databases

ReactomeiR-HSA-114608 Platelet degranulation
R-HSA-202733 Cell surface interactions at the vascular wall
SIGNORiP16109

Miscellaneous databases

EvolutionaryTraceiP16109
GeneWikiiP-selectin
GenomeRNAii6403
PROiPR:P16109
SOURCEiSearch...

Gene expression databases

BgeeiENSG00000174175 Expressed in 136 organ(s), highest expression level in adrenal gland
CleanExiHS_SELP
ExpressionAtlasiP16109 baseline and differential
GenevisibleiP16109 HS

Family and domain databases

CDDicd00033 CCP, 9 hits
cd03592 CLECT_selectins_like, 1 hit
Gene3Di3.10.100.10, 1 hit
InterProiView protein in InterPro
IPR001304 C-type_lectin-like
IPR016186 C-type_lectin-like/link_sf
IPR018378 C-type_lectin_CS
IPR016187 CTDL_fold
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR033991 Selectin_CTLD
IPR002396 Selectin_superfamily
IPR035976 Sushi/SCR/CCP_sf
IPR000436 Sushi_SCR_CCP_dom
PfamiView protein in Pfam
PF00059 Lectin_C, 1 hit
PF00084 Sushi, 9 hits
PRINTSiPR00343 SELECTIN
SMARTiView protein in SMART
SM00032 CCP, 9 hits
SM00034 CLECT, 1 hit
SUPFAMiSSF56436 SSF56436, 1 hit
SSF57535 SSF57535, 9 hits
PROSITEiView protein in PROSITE
PS00615 C_TYPE_LECTIN_1, 1 hit
PS50041 C_TYPE_LECTIN_2, 1 hit
PS00022 EGF_1, 1 hit
PS01186 EGF_2, 1 hit
PS50026 EGF_3, 1 hit
PS50923 SUSHI, 9 hits
ProtoNetiSearch...

Entry informationi

Entry nameiLYAM3_HUMAN
AccessioniPrimary (citable) accession number: P16109
Secondary accession number(s): Q5R344, Q8IVD1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 1, 1990
Last sequence update: November 25, 2008
Last modified: September 12, 2018
This is version 215 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human cell differentiation molecules
    CD nomenclature of surface proteins of human leucocytes and list of entries
  4. SIMILARITY comments
    Index of protein domains and families
  5. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  6. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  7. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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