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Protein

Heat shock protein 26

Gene

HSP26

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Not known. One of the major polypeptides produced on heat shock.

Miscellaneous

Present with 19300 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functioni

  • identical protein binding Source: IntAct
  • mRNA binding Source: SGD
  • unfolded protein binding Source: SGD

GO - Biological processi

  • cellular response to heat Source: SGD
  • protein folding Source: SGD

Keywordsi

Biological processStress response

Enzyme and pathway databases

BioCyciYEAST:G3O-29041-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Heat shock protein 26
Alternative name(s):
26 kDa heat shock protein
Gene namesi
Name:HSP26
Ordered Locus Names:YBR072W
ORF Names:YBR0714
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:YBR072W
SGDiS000000276 HSP26

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedCombined sources1 Publication
ChainiPRO_00001260042 – 214Heat shock protein 26Add BLAST213

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylserineCombined sources1
Modified residuei42PhosphothreonineCombined sources1
Modified residuei90PhosphoserineCombined sources1
Modified residuei163PhosphothreonineCombined sources1
Modified residuei208PhosphoserineCombined sources1
Modified residuei211PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

MaxQBiP15992
PaxDbiP15992
PRIDEiP15992
TopDownProteomicsiP15992

PTM databases

CarbonylDBiP15992
iPTMnetiP15992

Expressioni

Developmental stagei

Expressed during the entry into stationary phase resulting from glucose limitation.

Inductioni

By heat shock, and under other conditions of stress, such as increased salt concentration and starvation.

Interactioni

Subunit structurei

Present in large complexes.

Binary interactionsi

Show more details

GO - Molecular functioni

  • identical protein binding Source: IntAct
  • unfolded protein binding Source: SGD

Protein-protein interaction databases

BioGridi32775, 95 interactors
DIPiDIP-3988N
IntActiP15992, 223 interactors
MINTiP15992
STRINGi4932.YBR072W

Structurei

3D structure databases

ProteinModelPortaliP15992
SMRiP15992
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini86 – 207sHSPPROSITE-ProRule annotationAdd BLAST122

Sequence similaritiesi

Belongs to the small heat shock protein (HSP20) family.PROSITE-ProRule annotation

Phylogenomic databases

HOGENOMiHOG000112974
InParanoidiP15992
KOiK13993
OMAiNINIEFH
OrthoDBiEOG092C5G0L

Family and domain databases

Gene3Di2.60.40.790, 1 hit
InterProiView protein in InterPro
IPR002068 A-crystallin/Hsp20_dom
IPR008978 HSP20-like_chaperone
PfamiView protein in Pfam
PF00011 HSP20, 1 hit
SUPFAMiSSF49764 SSF49764, 1 hit
PROSITEiView protein in PROSITE
PS01031 SHSP, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P15992-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSFNSPFFDF FDNINNEVDA FNRLLGEGGL RGYAPRRQLA NTPAKDSTGK
60 70 80 90 100
EVARPNNYAG ALYDPRDETL DDWFDNDLSL FPSGFGFPRS VAVPVDILDH
110 120 130 140 150
DNNYELKVVV PGVKSKKDID IEYHQNKNQI LVSGEIPSTL NEESKDKVKV
160 170 180 190 200
KESSSGKFKR VITLPDYPGV DADNIKADYA NGVLTLTVPK LKPQKDGKNH
210
VKKIEVSSQE SWGN
Length:214
Mass (Da):23,880
Last modified:January 23, 2007 - v3
Checksum:i0CB8B6BD22C5308F
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti32G → A in AAA79010 (PubMed:2673926).Curated1
Sequence conflicti207S → C in AAA79010 (PubMed:2673926).Curated1
Sequence conflicti212W → G in AAT92994 (PubMed:17322287).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M23871 Genomic DNA Translation: AAA66914.1
M26942 Genomic DNA Translation: AAA79010.1
X76294 Genomic DNA Translation: CAA53929.1
Z35941 Genomic DNA Translation: CAA85016.1
AY692975 Genomic DNA Translation: AAT92994.1
BK006936 Genomic DNA Translation: DAA07191.1
PIRiS45465
RefSeqiNP_009628.1, NM_001178420.1

Genome annotation databases

EnsemblFungiiYBR072W; YBR072W; YBR072W
GeneIDi852364
KEGGisce:YBR072W

Similar proteinsi

Entry informationi

Entry nameiHSP26_YEAST
AccessioniPrimary (citable) accession number: P15992
Secondary accession number(s): D6VQ71, Q6B1V5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 1, 1990
Last sequence update: January 23, 2007
Last modified: July 18, 2018
This is version 153 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome II
    Yeast (Saccharomyces cerevisiae) chromosome II: entries and gene names

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