Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Arsenical resistance operon repressor

Gene

arsR

Organism
Escherichia coli
Status
Reviewed-Annotation score: -Protein predictedi

Functioni

Transcriptional repressor for the ars operon. ArsR is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsR is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arsenate (As(V)).1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi33 – 52H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding, Repressor
Biological processArsenical resistance, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Arsenical resistance operon repressor
Gene namesi
Name:arsR
Encoded oniPlasmid R7730 Publication
OrganismiEscherichia coli
Taxonomic identifieri562 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001606111 – 117Arsenical resistance operon repressorAdd BLAST117

Proteomic databases

PRIDEiP15905

Interactioni

Subunit structurei

Binds DNA as a homodimer.

Structurei

3D structure databases

ProteinModelPortaliP15905
SMRiP15905
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 92HTH arsR-typePROSITE-ProRule annotationAdd BLAST92

Family and domain databases

CDDicd00090 HTH_ARSR, 1 hit
Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR011991 ArsR-like_HTH
IPR018334 ArsR_HTH
IPR001845 HTH_ArsR_DNA-bd_dom
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PfamiView protein in Pfam
PF01022 HTH_5, 1 hit
PRINTSiPR00778 HTHARSR
SMARTiView protein in SMART
SM00418 HTH_ARSR, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS00846 HTH_ARSR_1, 1 hit
PS50987 HTH_ARSR_2, 1 hit

Sequencei

Sequence statusi: Complete.

P15905-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLQLTPLQLF KNLSDETRLG IVLLLREMGE LCVCDLCMAL DQSQPKISRH
60 70 80 90 100
LAMLRESGIL LDRKQGKWVH YRLSPHIPSW AAQIIEQAWL SQQDDVQVIA
110
RKLASVNCSG SSKAVCI
Length:117
Mass (Da):13,199
Last modified:April 1, 1990 - v1
Checksum:i1F0D10766E4FD886
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X16045 Genomic DNA Translation: CAA34168.1
PIRiJS0448 BVECAR
RefSeqiWP_011117595.1, NZ_PGIU01000046.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X16045 Genomic DNA Translation: CAA34168.1
PIRiJS0448 BVECAR
RefSeqiWP_011117595.1, NZ_PGIU01000046.1

3D structure databases

ProteinModelPortaliP15905
SMRiP15905
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiP15905

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

CDDicd00090 HTH_ARSR, 1 hit
Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR011991 ArsR-like_HTH
IPR018334 ArsR_HTH
IPR001845 HTH_ArsR_DNA-bd_dom
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PfamiView protein in Pfam
PF01022 HTH_5, 1 hit
PRINTSiPR00778 HTHARSR
SMARTiView protein in SMART
SM00418 HTH_ARSR, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS00846 HTH_ARSR_1, 1 hit
PS50987 HTH_ARSR_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiARSR1_ECOLX
AccessioniPrimary (citable) accession number: P15905
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 1, 1990
Last sequence update: April 1, 1990
Last modified: September 12, 2018
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Plasmid
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again