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UniProtKB - P15556 (NDD_BPT4)
Protein
Nucleoid disruption protein
Gene
ndd
Organism
Enterobacteria phage T4 (Bacteriophage T4)
Status
Functioni
Disorganizes the host nucleoid and inhibits replication, but without host DNA cleavage or degradation. Only the architecture of the nucleoid is affected. May act on the host chromosomal sequences that determine the structure of the nucleoid. Binds to dsDNA but not to ssDNA.
1 PublicationGO - Molecular functioni
- DNA binding Source: UniProtKB-KW
GO - Biological processi
- inhibition of host DNA replication by virus Source: UniProtKB-KW
- modulation by virus of host cell cycle Source: UniProtKB-KW
Keywordsi
Molecular function | DNA-binding |
Biological process | Host-virus interaction, Inhibition of host DNA replication by virus, Modulation of host cell cycle by virus |
Names & Taxonomyi
Protein namesi | Recommended name: Nucleoid disruption protein |
Gene namesi | Name:ndd |
Organismi | Enterobacteria phage T4 (Bacteriophage T4) |
Taxonomic identifieri | 10665 [NCBI] |
Taxonomic lineagei | Viruses › Duplodnaviria › Heunggongvirae › Uroviricota › Caudoviricetes › Caudovirales › Myoviridae › Tevenvirinae › Tequatrovirus |
Virus hosti | Escherichia coli [TaxID: 562] |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000164959 | 1 – 151 | Nucleoid disruption proteinAdd BLAST | 151 |
Structurei
Family & Domainsi
Family and domain databases
InterProi | View protein in InterPro IPR009514, Phage_Ndd |
Pfami | View protein in Pfam PF06591, Phage_T4_Ndd, 1 hit |
i Sequence
Sequence statusi: Complete.
P15556-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKYMTVTDLN DAGATVIGTI KGGEWFLGTP HKDILSKPGF YFLVSKLGGP
60 70 80 90 100
FSNPCVSARF YVGNQRSKQG FSAVLSHIRQ RRSQLARTIA NNNVPYTVFY
110 120 130 140 150
LPASKMKPLT TGFGKGQLAL AFTRNHHSEY QTLEEMNRML ADNFKFVLQA
Y
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural varianti | 63 | G → D in mutant NDD44. | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X75802 Genomic DNA Translation: CAA53438.1 AF158101 Genomic DNA Translation: AAD42615.1 |
PIRi | S01868, NDBPT4 |
RefSeqi | NP_049879.1, NC_000866.4 |
Genome annotation databases
GeneIDi | 1258737 |
KEGGi | vg:1258737 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X75802 Genomic DNA Translation: CAA53438.1 AF158101 Genomic DNA Translation: AAD42615.1 |
PIRi | S01868, NDBPT4 |
RefSeqi | NP_049879.1, NC_000866.4 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
GeneIDi | 1258737 |
KEGGi | vg:1258737 |
Family and domain databases
InterProi | View protein in InterPro IPR009514, Phage_Ndd |
Pfami | View protein in Pfam PF06591, Phage_T4_Ndd, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | NDD_BPT4 | |
Accessioni | P15556Primary (citable) accession number: P15556 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 1, 1990 |
Last sequence update: | February 1, 1995 | |
Last modified: | December 2, 2020 | |
This is version 70 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Viral Protein Annotation Program |