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Protein

Cytochrome c oxidase subunit 3

Gene

COIII

Organism
Strongylocentrotus purpuratus (Purple sea urchin)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 3 (EC:1.9.3.1)
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene namesi
Name:COIII
Encoded oniMitochondrion
OrganismiStrongylocentrotus purpuratus (Purple sea urchin)
Taxonomic identifieri7668 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEchinodermataEleutherozoaEchinozoaEchinoideaEuechinoideaEchinaceaEchinoidaStrongylocentrotidaeStrongylocentrotus
Proteomesi
  • UP000007110 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei41 – 61HelicalSequence analysisAdd BLAST21
Transmembranei81 – 101HelicalSequence analysisAdd BLAST21
Transmembranei133 – 153HelicalSequence analysisAdd BLAST21
Transmembranei161 – 181HelicalSequence analysisAdd BLAST21
Transmembranei196 – 216HelicalSequence analysisAdd BLAST21
Transmembranei238 – 258HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001838581 – 260Cytochrome c oxidase subunit 3Add BLAST260

Proteomic databases

PRIDEiP15546

Structurei

3D structure databases

ProteinModelPortaliP15546
SMRiP15546
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoidiP15546

Family and domain databases

CDDicd01665 Cyt_c_Oxidase_III, 1 hit
Gene3Di1.20.120.80, 1 hit
InterProiView protein in InterPro
IPR024791 Cyt_c/ubiquinol_Oxase_su3
IPR033945 Cyt_c_oxase_su3_dom
IPR000298 Cyt_c_oxidase-like_su3
IPR035973 Cyt_c_oxidase_su3-like_sf
IPR013833 Cyt_c_oxidase_su3_a-hlx
PANTHERiPTHR11403 PTHR11403, 1 hit
PfamiView protein in Pfam
PF00510 COX3, 1 hit
SUPFAMiSSF81452 SSF81452, 1 hit
PROSITEiView protein in PROSITE
PS50253 COX3, 1 hit

Sequencei

Sequence statusi: Complete.

P15546-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAIQHPYHLV DQSPWPLDGA FSGLMMTSGN VLWFHTQKTN LTLVGFLLLI
60 70 80 90 100
TNMVNWWRDI IRKANFQGSH TAIVNKGMRY GMILFITSEV CFFFAFFWAF
110 120 130 140 150
FHSSLAPSVE IGVAWPPSGI TPLNPFLVPL LNTGVLLSSG VTLSWSHHSI
160 170 180 190 200
LAGNRTESIQ ALFLTVALGS YFTALQAWEY IDAPFTIADS VYGSTFFVAT
210 220 230 240 250
GFHGLQVIIG TTFLMVCLFR TAGRHFSTHH HFGFEAAAWY WHFVDVVWFV
260
LYWLIYWWGA
Length:260
Mass (Da):29,489
Last modified:April 1, 1990 - v1
Checksum:i7416670412F81A00
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X12631 Genomic DNA No translation available.
PIRiS01506

Similar proteinsi

Entry informationi

Entry nameiCOX3_STRPU
AccessioniPrimary (citable) accession number: P15546
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 1, 1990
Last sequence update: April 1, 1990
Last modified: May 23, 2018
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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