Il9

Protein namesⁱ	Recommended name: Interleukin-9 Short name: IL-9 Alternative name(s): Cytokine P40 T-cell growth factor P40
Gene namesⁱ	Name:Il9
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 13

Organism-specific databases

MGIⁱ	MGI:96563 Il9

Keywords - Cellular componentⁱ

Secreted

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Signal peptideⁱ	1 – 18	1 PublicationAdd BLAST		18
ChainⁱPRO_0000015628	19 – 144	Interleukin-9Add BLAST		126

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Modified residueⁱ	19	Pyrrolidone carboxylic acid1 Publication	1
Glycosylationⁱ	50	N-linked (GlcNAc...) asparagine1 Publication	1
Glycosylationⁱ	78	N-linked (GlcNAc...) asparagine1 Publication	1
Glycosylationⁱ	101	N-linked (GlcNAc...) asparagine1 Publication	1
Glycosylationⁱ	114	N-linked (GlcNAc...) asparagine1 Publication	1

Keywords - PTMⁱ

Glycoprotein, Pyrrolidone carboxylic acid

Proteomic databases

PaxDbⁱ	P15247
PRIDEⁱ	P15247

PTM databases

iPTMnetⁱ	P15247
PhosphoSitePlusⁱ	P15247

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000021538 Expressed in 20 organ(s), highest expression level in adipose tissue
CleanExⁱ	MM_IL9
Genevisibleⁱ	P15247 MM

Interactionⁱ

GO - Molecular functionⁱ

cytokine activity Source: MGI
growth factor activity Source: UniProtKB-KW
interleukin-9 receptor binding Source: MGI

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

STRINGⁱ	10090.ENSMUSP00000022019

STRINGⁱ

10090.ENSMUSP00000022019

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P15247
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the IL-7/IL-9 family.Curated

Keywords - Domainⁱ

Signal

Phylogenomic databases

eggNOGⁱ	ENOG410IYR9 Eukaryota ENOG41114M6 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000015384
HOGENOMⁱ	HOG000113052
HOVERGENⁱ	HBG003933
InParanoidⁱ	P15247
KEGG Orthology (KO) More...KOⁱ	K05432
OMAⁱ	CLCLPIP
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0U4U
PhylomeDBⁱ	P15247
TreeFamⁱ	TF336367

Family and domain databases

InterProⁱ	View protein in InterPro IPR018049 IL-7/IL-9_CS IPR000226 IL-7/IL-9_fam IPR020447 IL-9
PANTHERⁱ	PTHR16926 PTHR16926, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01415 IL7, 1 hit
PRINTSⁱ	PR01926 INTERLEUKIN9
ProDomⁱ	View protein in ProDom or Entries sharing at least one domain PD033324 PD033324, 1 hit
PROSITEⁱ	View protein in PROSITE PS00255 INTERLEUKIN_7_9, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

P15247-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MLVTYILASV LLFSSVLGQR CSTTWGIRDT NYLIENLKDD PPSKCSCSGN 
        60         70         80         90        100
VTSCLCLSVP TDDCTTPCYR EGLLQLTNAT QKSRLLPVFH RVKRIVEVLK 
       110        120        130        140 
NITCPSFSCE KPCNQTMAGN TLSFLKSLLG TFQKTEMQRQ KSRP

Length:144

Mass (Da):16,075

Last modified:April 1, 1990 - v1

Checksum:ⁱECD944632CE837C7

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	X14045 mRNA Translation: CAA32203.1 M30136 Genomic DNA Translation: AAA39874.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS26562.1
PIRⁱ	JL0089
NCBI Reference Sequences More...RefSeqⁱ	NP_032399.1, NM_008373.1
UniGeneⁱ	Mm.3006

Genome annotation databases

Ensemblⁱ	ENSMUST00000022019; ENSMUSP00000022019; ENSMUSG00000021538
GeneIDⁱ	16198
KEGGⁱ	mmu:16198
UCSC genome browser More...UCSCⁱ	uc007qso.1 mouse

Similar proteinsⁱ

50% Identity

Protein	Similar proteins		Species	Score	Length	Source
P15247	interleukin-9		Yangtze finless porpoise		141	UniRef50_P15247
interleukin-9		DELLE		141
interleukin-9		PHYCD		141
interleukin-9		BALAS		141
interleukin-9		LIPVE		141
+4

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	X14045 mRNA Translation: CAA32203.1 M30136 Genomic DNA Translation: AAA39874.1
CCDSⁱ	CCDS26562.1
PIRⁱ	JL0089
RefSeqⁱ	NP_032399.1, NM_008373.1
UniGeneⁱ	Mm.3006

3D structure databases

ProteinModelPortalⁱ	P15247
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10090.ENSMUSP00000022019

STRINGⁱ

10090.ENSMUSP00000022019

PTM databases

iPTMnetⁱ	P15247
PhosphoSitePlusⁱ	P15247

Proteomic databases

PaxDbⁱ	P15247
PRIDEⁱ	P15247

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	16198
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000022019; ENSMUSP00000022019; ENSMUSG00000021538
GeneIDⁱ	16198
KEGGⁱ	mmu:16198
UCSCⁱ	uc007qso.1 mouse

Organism-specific databases

CTDⁱ	3578
MGIⁱ	MGI:96563 Il9

Phylogenomic databases

eggNOGⁱ	ENOG410IYR9 Eukaryota ENOG41114M6 LUCA
GeneTreeⁱ	ENSGT00390000015384
HOGENOMⁱ	HOG000113052
HOVERGENⁱ	HBG003933
InParanoidⁱ	P15247
KOⁱ	K05432
OMAⁱ	CLCLPIP
OrthoDBⁱ	EOG091G0U4U
PhylomeDBⁱ	P15247
TreeFamⁱ	TF336367

Enzyme and pathway databases

Reactomeⁱ	R-MMU-8985947 Interleukin-9 signaling

Reactomeⁱ

R-MMU-8985947 Interleukin-9 signaling

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:P15247
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000021538 Expressed in 20 organ(s), highest expression level in adipose tissue
CleanExⁱ	MM_IL9
Genevisibleⁱ	P15247 MM

Family and domain databases

InterProⁱ	View protein in InterPro IPR018049 IL-7/IL-9_CS IPR000226 IL-7/IL-9_fam IPR020447 IL-9
PANTHERⁱ	PTHR16926 PTHR16926, 1 hit
Pfamⁱ	View protein in Pfam PF01415 IL7, 1 hit
PRINTSⁱ	PR01926 INTERLEUKIN9
ProDomⁱ	View protein in ProDom or Entries sharing at least one domain PD033324 PD033324, 1 hit
PROSITEⁱ	View protein in PROSITE PS00255 INTERLEUKIN_7_9, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	IL9_MOUSE
Accessionⁱ	P15247Primary (citable) accession number: P15247
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	April 1, 1990
	Last sequence update:	April 1, 1990
	Last modified:	November 7, 2018
	This is version 126 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Direct protein sequencing, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - P15247 (IL9_MOUSE)

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Interleukin-9

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted

Extracellular region or secreted

Keywords - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ