UniProtKB - P15207 (ANDR_RAT)
Androgen receptor
Ar
Functioni
Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3 (By similarity).
By similarity2 PublicationsMiscellaneous
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 688 | 17beta-hydroxy-5alpha-androstan-3-oneCombined sources1 Publication | 1 | |
Binding sitei | 735 | 17beta-hydroxy-5alpha-androstan-3-oneCombined sources1 Publication | 1 | |
Binding sitei | 860 | 17beta-hydroxy-5alpha-androstan-3-oneCombined sources1 Publication | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 541 – 614 | Nuclear receptorPROSITE-ProRule annotationAdd BLAST | 74 | |
Zinc fingeri | 542 – 562 | NR C4-typePROSITE-ProRule annotationAdd BLAST | 21 | |
Zinc fingeri | 578 – 602 | NR C4-typePROSITE-ProRule annotationAdd BLAST | 25 |
GO - Molecular functioni
- androgen binding Source: RGD
- androgen receptor binding Source: RGD
- ATPase binding Source: RGD
- beta-catenin binding Source: UniProtKB
- chromatin binding Source: RGD
- DNA binding Source: RGD
- DNA-binding transcription activator activity, RNA polymerase II-specific Source: RGD
- DNA-binding transcription factor activity Source: UniProtKB
- enzyme binding Source: RGD
- nuclear receptor activity Source: RGD
- POU domain binding Source: RGD
- protein domain specific binding Source: RGD
- ribonucleotide binding Source: RGD
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: RGD
- RNA polymerase II general transcription initiation factor binding Source: RGD
- RNA polymerase II-specific DNA-binding transcription factor binding Source: RGD
- sequence-specific DNA binding Source: RGD
- signaling receptor binding Source: UniProtKB
- steroid binding Source: UniProtKB-KW
- transcription cis-regulatory region binding Source: UniProtKB
- transcription coactivator binding Source: RGD
- zinc ion binding Source: InterPro
GO - Biological processi
- activation of prostate induction by androgen receptor signaling pathway Source: RGD
- androgen receptor signaling pathway Source: RGD
- animal organ formation Source: RGD
- cellular response to estrogen stimulus Source: RGD
- cellular response to follicle-stimulating hormone stimulus Source: RGD
- cellular response to steroid hormone stimulus Source: RGD
- cellular response to testosterone stimulus Source: RGD
- copulation Source: RGD
- epithelial cell differentiation involved in prostate gland development Source: RGD
- epithelial cell morphogenesis Source: RGD
- fertilization Source: RGD
- intracellular estrogen receptor signaling pathway Source: RGD
- intracellular receptor signaling pathway Source: UniProtKB
- intracellular steroid hormone receptor signaling pathway Source: GO_Central
- in utero embryonic development Source: RGD
- lateral sprouting involved in mammary gland duct morphogenesis Source: RGD
- Leydig cell differentiation Source: RGD
- male courtship behavior Source: RGD
- male genitalia morphogenesis Source: RGD
- male gonad development Source: RGD
- male sex differentiation Source: RGD
- male somatic sex determination Source: RGD
- mammary gland alveolus development Source: RGD
- morphogenesis of an epithelial fold Source: RGD
- multicellular organism growth Source: RGD
- negative regulation of cell population proliferation Source: RGD
- negative regulation of epithelial cell proliferation Source: RGD
- negative regulation of extrinsic apoptotic signaling pathway Source: UniProtKB
- negative regulation of integrin biosynthetic process Source: UniProtKB
- negative regulation of transcription, DNA-templated Source: RGD
- negative regulation of transcription by RNA polymerase II Source: RGD
- positive regulation of cell differentiation Source: RGD
- positive regulation of cell population proliferation Source: UniProtKB
- positive regulation of epithelial cell proliferation involved in prostate gland development Source: RGD
- positive regulation of gene expression Source: RGD
- positive regulation of insulin-like growth factor receptor signaling pathway Source: RGD
- positive regulation of integrin biosynthetic process Source: RGD
- positive regulation of intracellular estrogen receptor signaling pathway Source: RGD
- positive regulation of MAPK cascade Source: RGD
- positive regulation of NF-kappaB transcription factor activity Source: UniProtKB
- positive regulation of penile erection Source: RGD
- positive regulation of phosphorylation Source: UniProtKB
- positive regulation of transcription, DNA-templated Source: RGD
- positive regulation of transcription by RNA polymerase II Source: UniProtKB
- positive regulation of transcription by RNA polymerase III Source: RGD
- prostate gland epithelium morphogenesis Source: RGD
- prostate gland growth Source: RGD
- regulation of developmental growth Source: RGD
- regulation of gene expression Source: RGD
- regulation of prostatic bud formation Source: RGD
- regulation of protein localization to plasma membrane Source: UniProtKB
- regulation of systemic arterial blood pressure Source: RGD
- regulation of transcription, DNA-templated Source: RGD
- regulation of transcription by RNA polymerase II Source: RGD
- reproductive behavior Source: RGD
- reproductive structure development Source: RGD
- reproductive system development Source: RGD
- response to estradiol Source: RGD
- response to insulin Source: RGD
- response to testosterone Source: RGD
- seminiferous tubule development Source: RGD
- single fertilization Source: RGD
- skeletal muscle hypertrophy Source: RGD
- spermatogenesis Source: RGD
- tertiary branching involved in mammary gland duct morphogenesis Source: RGD
Keywordsi
Molecular function | DNA-binding, Receptor |
Biological process | Transcription, Transcription regulation |
Ligand | Lipid-binding, Metal-binding, Steroid-binding, Zinc |
Enzyme and pathway databases
Reactomei | R-RNO-3371497, HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-RNO-383280, Nuclear Receptor transcription pathway R-RNO-4090294, SUMOylation of intracellular receptors R-RNO-5625886, Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-RNO-5689880, Ub-specific processing proteases |
Names & Taxonomyi
Protein namesi | Recommended name: Androgen receptorAlternative name(s): Dihydrotestosterone receptor Nuclear receptor subfamily 3 group C member 4 |
Gene namesi | Name:Ar Synonyms:Nr3c4 |
Organismi | Rattus norvegicus (Rat) |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 2147, Ar |
Subcellular locationi
Cytoplasm and Cytosol
- Cytoplasm By similarity
Nucleus
- Nucleus 1 Publication
Note: Detected at the promoter of target genes. Predominantly cytoplasmic in unligated form but translocates to the nucleus upon ligand-binding. Can also translocate to the nucleus in unligated form in the presence of RACK1.By similarity
Nucleus
- nuclear speck Source: RGD
- nucleus Source: RGD
Plasma Membrane
- plasma membrane Source: RGD
Other locations
- axon Source: RGD
- chromatin Source: UniProtKB
- cytoplasm Source: RGD
- dendrite Source: RGD
- protein-containing complex Source: RGD
Keywords - Cellular componenti
Cytoplasm, NucleusPathology & Biotechi
Involvement in diseasei
Keywords - Diseasei
Disease variantChemistry databases
ChEMBLi | CHEMBL3072 |
DrugCentrali | P15207 |
GuidetoPHARMACOLOGYi | 628 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000053712 | 1 – 902 | Androgen receptorAdd BLAST | 902 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 61 | Phosphoserine; by CDK9By similarity | 1 | |
Modified residuei | 75 | PhosphoserineBy similarity | 1 | |
Modified residuei | 221 | Phosphotyrosine; by CSKBy similarity | 1 | |
Modified residuei | 254 | PhosphoserineBy similarity | 1 | |
Modified residuei | 265 | Phosphotyrosine; by CSK and TNK2By similarity | 1 | |
Modified residuei | 290 | PhosphoserineCombined sources | 1 | |
Modified residuei | 305 | Phosphotyrosine; by CSKBy similarity | 1 | |
Modified residuei | 344 | Phosphotyrosine; by CSKBy similarity | 1 | |
Modified residuei | 355 | Phosphotyrosine; by CSKBy similarity | 1 | |
Modified residuei | 360 | Phosphotyrosine; by CSKBy similarity | 1 | |
Modified residuei | 361 | Phosphotyrosine; by CSK and TNK2By similarity | 1 | |
Cross-linki | 384 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)By similarity | ||
Modified residuei | 391 | Phosphotyrosine; by CSKBy similarity | 1 | |
Cross-linki | 503 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)By similarity | ||
Modified residuei | 517 | Phosphotyrosine; by CSKBy similarity | 1 | |
Modified residuei | 534 | Phosphotyrosine; by CSKBy similarity | 1 | |
Modified residuei | 633 | PhosphoserineCombined sources | 1 | |
Cross-linki | 828 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)By similarity | ||
Cross-linki | 830 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)By similarity | ||
Modified residuei | 898 | Phosphotyrosine; by CSKBy similarity | 1 |
Post-translational modificationi
Keywords - PTMi
Isopeptide bond, Lipoprotein, Palmitate, Phosphoprotein, Ubl conjugationProteomic databases
PaxDbi | P15207 |
PRIDEi | P15207 |
PTM databases
iPTMneti | P15207 |
PhosphoSitePlusi | P15207 |
Expressioni
Tissue specificityi
Interactioni
Subunit structurei
Binds DNA as a homodimer.
Part of a ternary complex containing AR, EFCAB6/DJBP and PARK7.
Interacts with HIPK3 and NR0B2 in the presence of androgen. The ligand binding domain interacts with KAT7/HBO1 in the presence of dihydrotestosterone.
Interacts with EFCAB6/DJBP, PQBP1, RANBP9, RBAK, SPDEF, SRA1, TGFB1I1, ZNF318 and RREB1.
Interacts with ZMIZ1/ZIMP10 and ZMIZ2/ZMIP7 which both enhance its transactivation activity.
Interacts with SLC30A9 and RAD54L2/ARIP4.
Interacts with MACROD1 (via macro domain) (By similarity).
Interacts via the ligand-binding domain with LXXLL and FXXLF motifs from NCOA1, NCOA2, NCOA3, NCOA4 and MAGEA11. The AR N-terminal poly-Gln region binds Ran resulting in enhancement of AR-mediated transactivation. Ran-binding decreases as the poly-Gln length increases.
Interacts with HIP1 (via coiled coil domain).
Interacts (via ligand-binding domain) with TRIM68.
Interacts with TNK2.
Interacts with USP26.
Interacts with RNF6.
Interacts (regulated by RNF6 probably through polyubiquitination) with RNF14; regulates AR transcriptional activity.
Interacts with PRMT2 and TRIM24.
Interacts with RACK1.
Interacts with RANBP10; this interaction enhances dihydrotestosterone-induced AR transcriptional activity.
Interacts with PRPF6 in a hormone-independent way; this interaction enhances dihydrotestosterone-induced AR transcriptional activity.
Interacts with STK4/MST1.
Interacts with ZIPK/DAPK3.
Interacts with LPXN.
Interacts with MAK.
Part of a complex containing AR, MAK and NCOA3.
Interacts with CRY1.
Interacts with CCAR1 and GATA2 (By similarity).
Interacts with BUD31 (By similarity).
Interacts with ARID4A (By similarity).
Interacts with ARID4B (By similarity).
Interacts (via NR LBD domain) with ZBTB7A; the interaction is direct and androgen-dependent (By similarity).
Interacts with NCOR1 (By similarity).
Interacts with NCOR2 (By similarity).
Interacts with CRY2 in a ligand-dependent manner (By similarity).
By similarity7 PublicationsSites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sitei | 703 | Interaction with coactivator LXXL and FXXFY motifsBy similarity | 1 | |
Sitei | 880 | Interaction with coactivator FXXLF and FXXFY motifsBy similarity | 1 |
GO - Molecular functioni
- androgen receptor binding Source: RGD
- ATPase binding Source: RGD
- beta-catenin binding Source: UniProtKB
- enzyme binding Source: RGD
- POU domain binding Source: RGD
- protein domain specific binding Source: RGD
- RNA polymerase II general transcription initiation factor binding Source: RGD
- RNA polymerase II-specific DNA-binding transcription factor binding Source: RGD
- signaling receptor binding Source: UniProtKB
- transcription coactivator binding Source: RGD
Protein-protein interaction databases
BioGRIDi | 246396, 3 interactors |
DIPi | DIP-5963N |
IntActi | P15207, 1 interactor |
STRINGi | 10116.ENSRNOP00000009129 |
Chemistry databases
BindingDBi | P15207 |
Structurei
Secondary structure
3D structure databases
SMRi | P15207 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P15207 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 651 – 882 | NR LBDPROSITE-ProRule annotationAdd BLAST | 232 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 569 | Interaction with ZNF318By similarityAdd BLAST | 569 | |
Regioni | 1 – 540 | ModulatingAdd BLAST | 540 | |
Regioni | 35 – 146 | DisorderedSequence analysisAdd BLAST | 112 | |
Regioni | 194 – 224 | DisorderedSequence analysisAdd BLAST | 31 | |
Regioni | 439 – 465 | DisorderedSequence analysisAdd BLAST | 27 | |
Regioni | 534 – 901 | Interaction with LPXNBy similarityAdd BLAST | 368 | |
Regioni | 554 – 644 | Interaction with HIPK31 PublicationAdd BLAST | 91 | |
Regioni | 574 – 901 | Interaction with CCAR1By similarityAdd BLAST | 328 | |
Regioni | 607 – 901 | Interaction with KAT7By similarityAdd BLAST | 295 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 59 – 74 | Basic and acidic residuesSequence analysisAdd BLAST | 16 | |
Compositional biasi | 89 – 105 | Polar residuesSequence analysisAdd BLAST | 17 |
Domaini
Sequence similaritiesi
Zinc finger
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 542 – 562 | NR C4-typePROSITE-ProRule annotationAdd BLAST | 21 | |
Zinc fingeri | 578 – 602 | NR C4-typePROSITE-ProRule annotationAdd BLAST | 25 |
Keywords - Domaini
Zinc-fingerPhylogenomic databases
eggNOGi | KOG3575, Eukaryota |
InParanoidi | P15207 |
OrthoDBi | 615449at2759 |
PhylomeDBi | P15207 |
TreeFami | TF350286 |
Family and domain databases
Gene3Di | 1.10.565.10, 1 hit 3.30.50.10, 1 hit |
InterProi | View protein in InterPro IPR001103, Andrgn_rcpt IPR035500, NHR-like_dom_sf IPR000536, Nucl_hrmn_rcpt_lig-bd IPR001628, Znf_hrmn_rcpt IPR013088, Znf_NHR/GATA |
Pfami | View protein in Pfam PF02166, Androgen_recep, 1 hit PF00104, Hormone_recep, 1 hit PF00105, zf-C4, 1 hit |
PRINTSi | PR00521, ANDROGENR PR00047, STROIDFINGER |
SMARTi | View protein in SMART SM00430, HOLI, 1 hit SM00399, ZnF_C4, 1 hit |
SUPFAMi | SSF48508, SSF48508, 1 hit |
PROSITEi | View protein in PROSITE PS51843, NR_LBD, 1 hit PS00031, NUCLEAR_REC_DBD_1, 1 hit PS51030, NUCLEAR_REC_DBD_2, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
10 20 30 40 50
MEVQLGLGRV YPRPPSKTYR GAFQNLFQSV REAIQNPGPR HPEAASIAPP
60 70 80 90 100
GACLQQRQET SPRRRRRQQH PEDGSPQAHI RGTTGYLALE EEQQPSQQQS
110 120 130 140 150
ASEGHPESGC LPEPGAATAP GKGLPQQPPA PPDQDDSAAP STLSLLGPTF
160 170 180 190 200
PGLSSCSADI KDILSEAGTM QLLQQQQQQQ QQQQQQQQQQ QQQQQEVISE
210 220 230 240 250
GSSSVRAREA TGAPSSSKDS YLGGNSTISD SAKELCKAVS VSMGLGVEAL
260 270 280 290 300
EHLSPGEQLR GDCMYASLLG GPPAVRPTPC APLAECKGLS LDEGPGKGTE
310 320 330 340 350
ETAEYSSFKG GYAKGLEGES LGCSGSSEAG SSGTLEIPSS LSLYKSGAVD
360 370 380 390 400
EAAAYQNRDY YNFPLALSGP PHPPPPTHPH ARIKLENPSD YGSAWAAAAA
410 420 430 440 450
QCRYGDLASL HGGSVAGPST GSPPATASSS WHTLFTAEEG QLYGPGGGGG
460 470 480 490 500
SSSPSDAGPV APYGYTRPPQ GLASQEGDFS ASEVWYPGGV VNRVPYPSPS
510 520 530 540 550
CVKSEMGPWM ENYSGPYGDM RLDSTRDHVL PIDYYFPPQK TCLICGDEAS
560 570 580 590 600
GCHYGALTCG SCKVFFKRAA EGKQKYLCAS RNDCTIDKFR RKNCPSCRLR
610 620 630 640 650
KCYEAGMTLG ARKLKKLGNL KLQEEGENSS AGSPTEDPSQ KMTVSHIEGY
660 670 680 690 700
ECQPIFLNVL EAIEPGVVCA GHDNNQPDSF AALLSSLNEL GERQLVHVVK
710 720 730 740 750
WAKALPGFRN LHVDDQMAVI QYSWMGLMVF AMGWRSFTNV NSRMLYFAPD
760 770 780 790 800
LVFNEYRMHK SRMYSQCVRM RHLSQEFGWL QITPQEFLCM KALLLFSIIP
810 820 830 840 850
VDGLKNQKFF DELRMNYIKE LDRIIACKRK NPTSCSRRFY QLTKLLDSVQ
860 870 880 890 900
PIARELHQFT FDLLIKSHMV SVDFPEMMAE IISVQVPKIL SGKVKPIYFH
TQ
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A0G2JSI8 | A0A0G2JSI8_RAT | Androgen receptor | Ar rCG_36439 | 902 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 195 | Missing in AAA40734 (PubMed:2341409).Curated | 1 | |
Sequence conflicti | 389 | S → L in AAA40759 (PubMed:3174628).Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural varianti | 735 | R → Q in TFM; has only 10-15% of the androgen-binding capacity of wild-type AR. 1 Publication | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M20133 mRNA Translation: AAA40733.1 M23264 mRNA Translation: AAA40759.1 J05454 Genomic DNA Translation: AAA40734.1 |
PIRi | B40494 |
RefSeqi | NP_036634.1, NM_012502.1 |
Genome annotation databases
GeneIDi | 24208 |
KEGGi | rno:24208 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M20133 mRNA Translation: AAA40733.1 M23264 mRNA Translation: AAA40759.1 J05454 Genomic DNA Translation: AAA40734.1 |
PIRi | B40494 |
RefSeqi | NP_036634.1, NM_012502.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1I37 | X-ray | 2.00 | A | 647-902 | [»] | |
1I38 | X-ray | 2.00 | A | 647-902 | [»] | |
1R4I | X-ray | 3.10 | A/B | 533-637 | [»] | |
1XNN | X-ray | 2.20 | A | 647-902 | [»] | |
2IHQ | X-ray | 2.00 | A | 647-902 | [»] | |
2NW4 | X-ray | 3.00 | A | 647-902 | [»] | |
3G0W | X-ray | 1.95 | A | 647-902 | [»] | |
SMRi | P15207 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 246396, 3 interactors |
DIPi | DIP-5963N |
IntActi | P15207, 1 interactor |
STRINGi | 10116.ENSRNOP00000009129 |
Chemistry databases
BindingDBi | P15207 |
ChEMBLi | CHEMBL3072 |
DrugCentrali | P15207 |
GuidetoPHARMACOLOGYi | 628 |
PTM databases
iPTMneti | P15207 |
PhosphoSitePlusi | P15207 |
Proteomic databases
PaxDbi | P15207 |
PRIDEi | P15207 |
Genome annotation databases
GeneIDi | 24208 |
KEGGi | rno:24208 |
Organism-specific databases
CTDi | 367 |
RGDi | 2147, Ar |
Phylogenomic databases
eggNOGi | KOG3575, Eukaryota |
InParanoidi | P15207 |
OrthoDBi | 615449at2759 |
PhylomeDBi | P15207 |
TreeFami | TF350286 |
Enzyme and pathway databases
Reactomei | R-RNO-3371497, HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-RNO-383280, Nuclear Receptor transcription pathway R-RNO-4090294, SUMOylation of intracellular receptors R-RNO-5625886, Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-RNO-5689880, Ub-specific processing proteases |
Miscellaneous databases
EvolutionaryTracei | P15207 |
PROi | PR:P15207 |
Family and domain databases
Gene3Di | 1.10.565.10, 1 hit 3.30.50.10, 1 hit |
InterProi | View protein in InterPro IPR001103, Andrgn_rcpt IPR035500, NHR-like_dom_sf IPR000536, Nucl_hrmn_rcpt_lig-bd IPR001628, Znf_hrmn_rcpt IPR013088, Znf_NHR/GATA |
Pfami | View protein in Pfam PF02166, Androgen_recep, 1 hit PF00104, Hormone_recep, 1 hit PF00105, zf-C4, 1 hit |
PRINTSi | PR00521, ANDROGENR PR00047, STROIDFINGER |
SMARTi | View protein in SMART SM00430, HOLI, 1 hit SM00399, ZnF_C4, 1 hit |
SUPFAMi | SSF48508, SSF48508, 1 hit |
PROSITEi | View protein in PROSITE PS51843, NR_LBD, 1 hit PS00031, NUCLEAR_REC_DBD_1, 1 hit PS51030, NUCLEAR_REC_DBD_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | ANDR_RAT | |
Accessioni | P15207Primary (citable) accession number: P15207 Secondary accession number(s): Q63049 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 1, 1990 |
Last sequence update: | April 1, 1990 | |
Last modified: | February 23, 2022 | |
This is version 213 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families