Mycb

Functionⁱ

Seems to act as an inhibitor of cellular proliferation.By similarity

GO - Molecular functionⁱ

DNA-binding transcription factor activity Source: InterPro

View the complete GO annotation on QuickGO ...

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Protein B-Myc
Gene namesⁱ	Name:Mycb Synonyms:Bmyc
Organismⁱ	Rattus norvegicus (Rat)
Taxonomic identifierⁱ	10116 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus
Proteomesⁱ	UP000002494 Componentⁱ: Chromosome 3

Organism-specific databases

Rat genome database More...RGDⁱ	1584970 Bmyc

RGDⁱ

1584970 Bmyc

Keywords - Cellular componentⁱ

Nucleus

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000127340	1 – 168	Protein B-MycAdd BLAST		168

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Modified residueⁱ	59	PhosphoserineBy similarity		1
Modified residueⁱ	67	PhosphoserineBy similarity		1

Keywords - PTMⁱ

Phosphoprotein

Proteomic databases

PaxDbⁱ	P15063
PRIDEⁱ	P15063

PTM databases

PhosphoSitePlusⁱ	P15063

PhosphoSitePlusⁱ

P15063

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSRNOG00000042556 Expressed in 10 organ(s), highest expression level in brain
Genevisibleⁱ	P15063 RN

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000059721

STRINGⁱ

10116.ENSRNOP00000059721

Family & Domainsⁱ

Phylogenomic databases

Ensembl GeneTree More...GeneTreeⁱ	ENSGT00510000046414
HOGENOMⁱ	HOG000041253
HOVERGENⁱ	HBG079592
InParanoidⁱ	P15063
KEGG Orthology (KO) More...KOⁱ	K09111
OMAⁱ	WNGFSAS
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0ZJQ
PhylomeDBⁱ	P15063

Family and domain databases

InterProⁱ	View protein in InterPro IPR002418 Tscrpt_reg_Myc IPR012682 Tscrpt_reg_Myc_N
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01056 Myc_N, 1 hit
PRINTSⁱ	PR00044 LEUZIPPRMYC

Sequenceⁱ

Sequence statusⁱ: Complete.

P15063-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MPLHVSLANG NRDLDYDSVQ PYFMCDDEEE DVHQQPPQPP APSEDIWKKF 
        60         70         80         90        100
ELLPTPRPSP GHPGLYSPPC EAVAASFSPR DHDGDSFSTA DLPELPGDAV 
       110        120        130        140        150
KQSFVCDPDD ETFVKNIILQ DCMWNGFSAS AKLVSKLDPY QAVRKEGASV 
       160 
SPAADVEPAT PPDCTCNT

Length:168

Mass (Da):18,317

Last modified:December 6, 2005 - v3

Checksum:ⁱB7BD2FA88D0D052C

GO

Sequence cautionⁱ

The sequence CAA35499 differs from that shown. Reason: Frameshift at position 156.Curated

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	X17455 Genomic DNA Translation: CAA35499.1 Frameshift. DQ191783 mRNA Translation: ABA40415.1 DQ191784 mRNA Translation: ABA40416.1 DQ191785 mRNA Translation: ABA40417.1 DQ191786 mRNA Translation: ABA40418.1 DQ191782 mRNA Translation: ABA40414.1 M21133 Genomic DNA No translation available.
PIRⁱ	A45502 TVRTBM
NCBI Reference Sequences More...RefSeqⁱ	NP_001013181.2, NM_001013163.2
UniGeneⁱ	Rn.11204

Genome annotation databases

Ensemblⁱ	ENSRNOT00000064358; ENSRNOP00000059721; ENSRNOG00000042556
GeneIDⁱ	311807
KEGGⁱ	rno:311807
UCSC genome browser More...UCSCⁱ	RGD:1584970 rat

Similar proteinsⁱ

90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
P15063	protein B-Myc		MESAU		197	UniRef90_P15063
Protein B-Myc		CRIGR		173
UPI00042AAEAD		PERMB		195

Protein	Similar proteins		Species	Score	Length	Source
P15063	Protein B-Myc		MOUSE		170	UniRef50_Q6P8Z1
protein B-Myc		MESAU		197
Protein B-Myc		CRIGR		173
UPI000A315E04		MUSCR		170
UPI000A312E0D		MUSPA		169
+4

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	X17455 Genomic DNA Translation: CAA35499.1 Frameshift. DQ191783 mRNA Translation: ABA40415.1 DQ191784 mRNA Translation: ABA40416.1 DQ191785 mRNA Translation: ABA40417.1 DQ191786 mRNA Translation: ABA40418.1 DQ191782 mRNA Translation: ABA40414.1 M21133 Genomic DNA No translation available.
PIRⁱ	A45502 TVRTBM
RefSeqⁱ	NP_001013181.2, NM_001013163.2
UniGeneⁱ	Rn.11204

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000059721

STRINGⁱ

10116.ENSRNOP00000059721

PTM databases

PhosphoSitePlusⁱ	P15063

PhosphoSitePlusⁱ

P15063

Proteomic databases

PaxDbⁱ	P15063
PRIDEⁱ	P15063

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSRNOT00000064358; ENSRNOP00000059721; ENSRNOG00000042556
GeneIDⁱ	311807
KEGGⁱ	rno:311807
UCSCⁱ	RGD:1584970 rat

Organism-specific databases

CTDⁱ	107771
RGDⁱ	1584970 Bmyc

Phylogenomic databases

GeneTreeⁱ	ENSGT00510000046414
HOGENOMⁱ	HOG000041253
HOVERGENⁱ	HBG079592
InParanoidⁱ	P15063
KOⁱ	K09111
OMAⁱ	WNGFSAS
OrthoDBⁱ	EOG091G0ZJQ
PhylomeDBⁱ	P15063

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:P15063

PROⁱ

PR:P15063

Gene expression databases

Bgeeⁱ	ENSRNOG00000042556 Expressed in 10 organ(s), highest expression level in brain
Genevisibleⁱ	P15063 RN

Family and domain databases

InterProⁱ	View protein in InterPro IPR002418 Tscrpt_reg_Myc IPR012682 Tscrpt_reg_Myc_N
Pfamⁱ	View protein in Pfam PF01056 Myc_N, 1 hit
PRINTSⁱ	PR00044 LEUZIPPRMYC
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	MYCB_RAT
Accessionⁱ	P15063Primary (citable) accession number: P15063 Secondary accession number(s): Q3HVJ5
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	April 1, 1990
	Last sequence update:	December 6, 2005
	Last modified:	September 12, 2018
	This is version 129 of the entry and version 3 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - P15063 (MYCB_RAT)

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Protein B-Myc

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Cytoskeleton

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

Family and domain databases

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

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Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Family & Domainsⁱ

Sequence cautionⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ