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UniProtKB - P15063 (MYCB_RAT)
Protein
Protein B-Myc
Gene
Mycb
Organism
Rattus norvegicus (Rat)
Status
Functioni
Seems to act as an inhibitor of cellular proliferation.
By similarityGO - Molecular functioni
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO_Central
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central
GO - Biological processi
- positive regulation of cell population proliferation Source: GO_Central
- regulation of transcription by RNA polymerase II Source: GO_Central
Names & Taxonomyi
Protein namesi | Recommended name: Protein B-Myc |
Gene namesi | Name:Mycb Synonyms:Bmyc |
Organismi | Rattus norvegicus (Rat) |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 1584970, Bmyc |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000127340 | 1 – 168 | Protein B-MycAdd BLAST | 168 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 59 | PhosphoserineBy similarity | 1 | |
Modified residuei | 67 | PhosphoserineBy similarity | 1 |
Keywords - PTMi
PhosphoproteinProteomic databases
PaxDbi | P15063 |
PTM databases
PhosphoSitePlusi | P15063 |
Expressioni
Gene expression databases
Bgeei | ENSRNOG00000042556, Expressed in cerebellum and 21 other tissues |
Genevisiblei | P15063, RN |
Structurei
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 26 – 94 | DisorderedSequence analysisAdd BLAST | 69 | |
Regioni | 146 – 168 | DisorderedSequence analysisAdd BLAST | 23 |
Phylogenomic databases
eggNOGi | KOG2483, Eukaryota |
GeneTreei | ENSGT00940000155285 |
HOGENOMi | CLU_135109_0_0_1 |
InParanoidi | P15063 |
OMAi | PDCTCNT |
OrthoDBi | 877891at2759 |
PhylomeDBi | P15063 |
Family and domain databases
InterProi | View protein in InterPro IPR002418, Tscrpt_reg_Myc IPR012682, Tscrpt_reg_Myc_N |
Pfami | View protein in Pfam PF01056, Myc_N, 1 hit |
PRINTSi | PR00044, LEUZIPPRMYC |
i Sequence
Sequence statusi: Complete.
P15063-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPLHVSLANG NRDLDYDSVQ PYFMCDDEEE DVHQQPPQPP APSEDIWKKF
60 70 80 90 100
ELLPTPRPSP GHPGLYSPPC EAVAASFSPR DHDGDSFSTA DLPELPGDAV
110 120 130 140 150
KQSFVCDPDD ETFVKNIILQ DCMWNGFSAS AKLVSKLDPY QAVRKEGASV
160
SPAADVEPAT PPDCTCNT
Sequence cautioni
The sequence CAA35499 differs from that shown. Reason: Frameshift.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X17455 Genomic DNA Translation: CAA35499.1 Frameshift. DQ191783 mRNA Translation: ABA40415.1 DQ191784 mRNA Translation: ABA40416.1 DQ191785 mRNA Translation: ABA40417.1 DQ191786 mRNA Translation: ABA40418.1 DQ191782 mRNA Translation: ABA40414.1 M21133 Genomic DNA No translation available. |
PIRi | A45502, TVRTBM |
RefSeqi | NP_001013181.2, NM_001013163.2 |
Genome annotation databases
Ensembli | ENSRNOT00000064358; ENSRNOP00000059721; ENSRNOG00000042556 |
GeneIDi | 311807 |
KEGGi | rno:311807 |
UCSCi | RGD:1584970, rat |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X17455 Genomic DNA Translation: CAA35499.1 Frameshift. DQ191783 mRNA Translation: ABA40415.1 DQ191784 mRNA Translation: ABA40416.1 DQ191785 mRNA Translation: ABA40417.1 DQ191786 mRNA Translation: ABA40418.1 DQ191782 mRNA Translation: ABA40414.1 M21133 Genomic DNA No translation available. |
PIRi | A45502, TVRTBM |
RefSeqi | NP_001013181.2, NM_001013163.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000059721 |
PTM databases
PhosphoSitePlusi | P15063 |
Proteomic databases
PaxDbi | P15063 |
Genome annotation databases
Ensembli | ENSRNOT00000064358; ENSRNOP00000059721; ENSRNOG00000042556 |
GeneIDi | 311807 |
KEGGi | rno:311807 |
UCSCi | RGD:1584970, rat |
Organism-specific databases
CTDi | 107771 |
RGDi | 1584970, Bmyc |
Phylogenomic databases
eggNOGi | KOG2483, Eukaryota |
GeneTreei | ENSGT00940000155285 |
HOGENOMi | CLU_135109_0_0_1 |
InParanoidi | P15063 |
OMAi | PDCTCNT |
OrthoDBi | 877891at2759 |
PhylomeDBi | P15063 |
Miscellaneous databases
PROi | PR:P15063 |
Gene expression databases
Bgeei | ENSRNOG00000042556, Expressed in cerebellum and 21 other tissues |
Genevisiblei | P15063, RN |
Family and domain databases
InterProi | View protein in InterPro IPR002418, Tscrpt_reg_Myc IPR012682, Tscrpt_reg_Myc_N |
Pfami | View protein in Pfam PF01056, Myc_N, 1 hit |
PRINTSi | PR00044, LEUZIPPRMYC |
MobiDBi | Search... |
Entry informationi
Entry namei | MYCB_RAT | |
Accessioni | P15063Primary (citable) accession number: P15063 Secondary accession number(s): Q3HVJ5 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 1, 1990 |
Last sequence update: | December 6, 2005 | |
Last modified: | September 29, 2021 | |
This is version 143 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |