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Protein

Protein B-Myc

Gene

Mycb

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Seems to act as an inhibitor of cellular proliferation.By similarity

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Recommended name:
Protein B-Myc
Gene namesi
Name:Mycb
Synonyms:Bmyc
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 3

Organism-specific databases

RGDi1584970 Bmyc

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001273401 – 168Protein B-MycAdd BLAST168

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei59PhosphoserineBy similarity1
Modified residuei67PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiP15063
PRIDEiP15063

PTM databases

PhosphoSitePlusiP15063

Expressioni

Gene expression databases

BgeeiENSRNOG00000042556 Expressed in 10 organ(s), highest expression level in brain
GenevisibleiP15063 RN

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000059721

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00510000046414
HOGENOMiHOG000041253
HOVERGENiHBG079592
InParanoidiP15063
KOiK09111
OMAiWNGFSAS
OrthoDBiEOG091G0ZJQ
PhylomeDBiP15063

Family and domain databases

InterProiView protein in InterPro
IPR002418 Tscrpt_reg_Myc
IPR012682 Tscrpt_reg_Myc_N
PfamiView protein in Pfam
PF01056 Myc_N, 1 hit
PRINTSiPR00044 LEUZIPPRMYC

Sequencei

Sequence statusi: Complete.

P15063-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPLHVSLANG NRDLDYDSVQ PYFMCDDEEE DVHQQPPQPP APSEDIWKKF
60 70 80 90 100
ELLPTPRPSP GHPGLYSPPC EAVAASFSPR DHDGDSFSTA DLPELPGDAV
110 120 130 140 150
KQSFVCDPDD ETFVKNIILQ DCMWNGFSAS AKLVSKLDPY QAVRKEGASV
160
SPAADVEPAT PPDCTCNT
Length:168
Mass (Da):18,317
Last modified:December 6, 2005 - v3
Checksum:iB7BD2FA88D0D052C
GO

Sequence cautioni

The sequence CAA35499 differs from that shown. Reason: Frameshift at position 156.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X17455 Genomic DNA Translation: CAA35499.1 Frameshift.
DQ191783 mRNA Translation: ABA40415.1
DQ191784 mRNA Translation: ABA40416.1
DQ191785 mRNA Translation: ABA40417.1
DQ191786 mRNA Translation: ABA40418.1
DQ191782 mRNA Translation: ABA40414.1
M21133 Genomic DNA No translation available.
PIRiA45502 TVRTBM
RefSeqiNP_001013181.2, NM_001013163.2
UniGeneiRn.11204

Genome annotation databases

EnsembliENSRNOT00000064358; ENSRNOP00000059721; ENSRNOG00000042556
GeneIDi311807
KEGGirno:311807
UCSCiRGD:1584970 rat

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X17455 Genomic DNA Translation: CAA35499.1 Frameshift.
DQ191783 mRNA Translation: ABA40415.1
DQ191784 mRNA Translation: ABA40416.1
DQ191785 mRNA Translation: ABA40417.1
DQ191786 mRNA Translation: ABA40418.1
DQ191782 mRNA Translation: ABA40414.1
M21133 Genomic DNA No translation available.
PIRiA45502 TVRTBM
RefSeqiNP_001013181.2, NM_001013163.2
UniGeneiRn.11204

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000059721

PTM databases

PhosphoSitePlusiP15063

Proteomic databases

PaxDbiP15063
PRIDEiP15063

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000064358; ENSRNOP00000059721; ENSRNOG00000042556
GeneIDi311807
KEGGirno:311807
UCSCiRGD:1584970 rat

Organism-specific databases

CTDi107771
RGDi1584970 Bmyc

Phylogenomic databases

GeneTreeiENSGT00510000046414
HOGENOMiHOG000041253
HOVERGENiHBG079592
InParanoidiP15063
KOiK09111
OMAiWNGFSAS
OrthoDBiEOG091G0ZJQ
PhylomeDBiP15063

Miscellaneous databases

PROiPR:P15063

Gene expression databases

BgeeiENSRNOG00000042556 Expressed in 10 organ(s), highest expression level in brain
GenevisibleiP15063 RN

Family and domain databases

InterProiView protein in InterPro
IPR002418 Tscrpt_reg_Myc
IPR012682 Tscrpt_reg_Myc_N
PfamiView protein in Pfam
PF01056 Myc_N, 1 hit
PRINTSiPR00044 LEUZIPPRMYC
ProtoNetiSearch...

Entry informationi

Entry nameiMYCB_RAT
AccessioniPrimary (citable) accession number: P15063
Secondary accession number(s): Q3HVJ5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 1, 1990
Last sequence update: December 6, 2005
Last modified: September 12, 2018
This is version 129 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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