UniProtKB - P14946 (MPAL1_LOLPR)
Protein
Pollen allergen Lol p 1
Gene
N/A
Organism
Lolium perenne (Perennial ryegrass)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Pollen allergen Lol p 1Alternative name(s): Allergen Lol p I Allergen R7 Allergen: Lol p 1 |
Organismi | Lolium perenne (Perennial ryegrass) |
Taxonomic identifieri | 4522 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › Liliopsida › Poales › Poaceae › BOP clade › Pooideae › Poodae › Poeae › Poeae Chloroplast Group 2 (Poeae type) › Loliinae › Lolium |
Subcellular locationi
Extracellular region or secreted
Extracellular region or secreted
- extracellular region Source: UniProtKB-SubCell
Keywords - Cellular componenti
SecretedPathology & Biotechi
Allergenic propertiesi
Causes an allergic reaction in human. Causes grass pollen allergy. Binds to IgE.
Keywords - Diseasei
AllergenProtein family/group databases
Allergomei | 450, Lol p 1 451, Lol p 1.0101 452, Lol p 1.0102 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 23 | 2 PublicationsAdd BLAST | 23 | |
ChainiPRO_0000008720 | 24 – 263 | Pollen allergen Lol p 1Add BLAST | 240 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 32 | N-linked (GlcNAc...) asparagineSequence analysis | 1 |
Keywords - PTMi
GlycoproteinFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 61 – 167 | Expansin-like EG45PROSITE-ProRule annotationAdd BLAST | 107 | |
Domaini | 181 – 262 | Expansin-like CBDPROSITE-ProRule annotationAdd BLAST | 82 |
Sequence similaritiesi
Keywords - Domaini
SignalFamily and domain databases
Gene3Di | 2.40.40.10, 1 hit 2.60.40.760, 1 hit |
InterProi | View protein in InterPro IPR007118, Expan_Lol_pI IPR007112, Expansin/allergen_DPBB_dom IPR007117, Expansin_CBD IPR036749, Expansin_CBD_sf IPR005795, LolPI IPR009009, RlpA-like_DPBB IPR036908, RlpA-like_sf |
Pfami | View protein in Pfam PF03330, DPBB_1, 1 hit PF01357, Expansin_C, 1 hit |
PRINTSi | PR01225, EXPANSNFAMLY PR00829, LOLP1ALLERGN |
SMARTi | View protein in SMART SM00837, DPBB_1, 1 hit |
SUPFAMi | SSF49590, SSF49590, 1 hit SSF50685, SSF50685, 1 hit |
PROSITEi | View protein in PROSITE PS50843, EXPANSIN_CBD, 1 hit PS50842, EXPANSIN_EG45, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P14946-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MASSSSVLLV VALFAVFLGS AHGIAKVPPG PNITAEYGDK WLDAKSTWYG
60 70 80 90 100
KPTGAGPKDN GGACGYKNVD KAPFNGMTGC GNTPIFKDGR GCGSCFEIKC
110 120 130 140 150
TKPESCSGEA VTVTITDDNE EPIAPYHFDL SGHAFGSMAK KGEEQNVRSA
160 170 180 190 200
GELELQFRRV KCKYPDDTKP TFHVEKASNP NYLAILVKYV DGDGDVVAVD
210 220 230 240 250
IKEKGKDKWI ELKESWGAVW RIDTPDKLTG PFTVRYTTEG GTKSEFEDVI
260
PEGWKADTSY SAK
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 28 | P → C AA sequence (PubMed:3718469).Curated | 1 | |
Sequence conflicti | 31 | P → C AA sequence (PubMed:3718469).Curated | 1 | |
Sequence conflicti | 48 | W → WW AA sequence (PubMed:3718469).Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural varianti | 68 | N → D. | 1 | |
Natural varianti | 177 | A → G. | 1 | |
Natural varianti | 210 | I → T. | 1 | |
Natural varianti | 246 | F → V. | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M57474 mRNA Translation: AAA63279.1 M57476 mRNA Translation: AAA63278.1 |
PIRi | A23341 B37881 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M57474 mRNA Translation: AAA63279.1 M57476 mRNA Translation: AAA63278.1 |
PIRi | A23341 B37881 |
3D structure databases
SMRi | P14946 |
ModBasei | Search... |
Protein family/group databases
Allergomei | 450, Lol p 1 451, Lol p 1.0101 452, Lol p 1.0102 |
Family and domain databases
Gene3Di | 2.40.40.10, 1 hit 2.60.40.760, 1 hit |
InterProi | View protein in InterPro IPR007118, Expan_Lol_pI IPR007112, Expansin/allergen_DPBB_dom IPR007117, Expansin_CBD IPR036749, Expansin_CBD_sf IPR005795, LolPI IPR009009, RlpA-like_DPBB IPR036908, RlpA-like_sf |
Pfami | View protein in Pfam PF03330, DPBB_1, 1 hit PF01357, Expansin_C, 1 hit |
PRINTSi | PR01225, EXPANSNFAMLY PR00829, LOLP1ALLERGN |
SMARTi | View protein in SMART SM00837, DPBB_1, 1 hit |
SUPFAMi | SSF49590, SSF49590, 1 hit SSF50685, SSF50685, 1 hit |
PROSITEi | View protein in PROSITE PS50843, EXPANSIN_CBD, 1 hit PS50842, EXPANSIN_EG45, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | MPAL1_LOLPR | |
Accessioni | P14946Primary (citable) accession number: P14946 Secondary accession number(s): P19964 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 1, 1990 |
Last sequence update: | August 1, 1991 | |
Last modified: | October 7, 2020 | |
This is version 106 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Direct protein sequencingDocuments
- Allergens
Nomenclature of allergens and list of entries - SIMILARITY comments
Index of protein domains and families