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UniProtKB - P14768 (XYNA_CELJU)
Protein
Endo-1,4-beta-xylanase A
Gene
xynA
Organism
Cellvibrio japonicus (strain Ueda107) (Pseudomonas fluorescens subsp. cellulosa)
Status
Functioni
Catalytic activityi
- Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans. EC:3.2.1.8
: xylan degradation Pathwayi
This protein is involved in the pathway xylan degradation, which is part of Glycan degradation.View all proteins of this organism that are known to be involved in the pathway xylan degradation and in Glycan degradation.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 391 | Proton donor | 1 | |
Active sitei | 510 | Nucleophile | 1 |
GO - Molecular functioni
- cellulose binding Source: InterPro
- endo-1,4-beta-xylanase activity Source: UniProtKB-EC
GO - Biological processi
- xylan catabolic process Source: UniProtKB-UniPathway
Keywordsi
Molecular function | Glycosidase, Hydrolase |
Biological process | Carbohydrate metabolism, Polysaccharide degradation, Xylan degradation |
Enzyme and pathway databases
UniPathwayi | UPA00114 |
Protein family/group databases
CAZyi | CBM10, Carbohydrate-Binding Module Family 10 CBM2, Carbohydrate-Binding Module Family 2 GH10, Glycoside Hydrolase Family 10 |
Names & Taxonomyi
Protein namesi | Recommended name: Endo-1,4-beta-xylanase A (EC:3.2.1.8)Short name: Xylanase A Alternative name(s): 1,4-beta-D-xylan xylanohydrolase A Short name: XYLA |
Gene namesi | Name:xynA Synonyms:xyn10A Ordered Locus Names:CJA_2471 |
Organismi | Cellvibrio japonicus (strain Ueda107) (Pseudomonas fluorescens subsp. cellulosa) |
Taxonomic identifieri | 498211 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Cellvibrionales › Cellvibrionaceae › Cellvibrio › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 26 | Add BLAST | 26 | |
ChainiPRO_0000007977 | 27 – 611 | Endo-1,4-beta-xylanase AAdd BLAST | 585 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 31 ↔ 125 | By similarity | ||
Disulfide bondi | 184 ↔ 215 | 1 Publication | ||
Disulfide bondi | 194 ↔ 209 | 1 Publication |
Keywords - PTMi
Disulfide bondStructurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | P14768 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P14768 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 27 – 128 | CBM2PROSITE-ProRule annotationAdd BLAST | 102 | |
Domaini | 183 – 212 | CBM10PROSITE-ProRule annotationAdd BLAST | 30 | |
Domaini | 281 – 607 | GH10PROSITE-ProRule annotationAdd BLAST | 327 |
Sequence similaritiesi
Belongs to the glycosyl hydrolase 10 (cellulase F) family.Curated
Keywords - Domaini
SignalPhylogenomic databases
eggNOGi | COG3693, Bacteria |
HOGENOMi | CLU_029617_0_0_6 |
OMAi | GADDWPL |
Family and domain databases
Gene3Di | 2.30.32.30, 1 hit 2.60.40.290, 1 hit |
InterProi | View protein in InterPro IPR001919, CBD2 IPR002883, CBM10/Dockerin_dom IPR036601, CBM10_sf IPR008965, CBM2/CBM3_carb-bd_dom_sf IPR012291, CBM2_carb-bd_dom_sf IPR018366, CBM2_CS IPR009031, CBM_fam10 IPR044846, GH10 IPR031158, GH10_AS IPR001000, GH10_dom IPR017853, Glycoside_hydrolase_SF |
PANTHERi | PTHR31490, PTHR31490, 1 hit |
Pfami | View protein in Pfam PF02013, CBM_10, 1 hit PF00553, CBM_2, 1 hit PF00331, Glyco_hydro_10, 1 hit |
PRINTSi | PR00134, GLHYDRLASE10 |
SMARTi | View protein in SMART SM00637, CBD_II, 1 hit SM01064, CBM_10, 1 hit SM00633, Glyco_10, 1 hit |
SUPFAMi | SSF49384, SSF49384, 1 hit SSF51445, SSF51445, 1 hit SSF57615, SSF57615, 1 hit |
PROSITEi | View protein in PROSITE PS51763, CBM10, 1 hit PS51173, CBM2, 1 hit PS00561, CBM2_A, 1 hit PS00591, GH10_1, 1 hit PS51760, GH10_2, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P14768-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MRTAMAKSLG AAAFLGAALF AHTLAAQTAT CSYNITNEWN TGYTGDITIT
60 70 80 90 100
NRGSSAINGW SVNWQYATNR LSSSWNANVS GSNPYSASNL SWNGNIQPGQ
110 120 130 140 150
SVSFGFQVNK NGGSAERPSV GGSICSGSVA SSSAPASSVP SSIASSSPSS
160 170 180 190 200
VASSVISSMA SSSPVSSSSV ASSTPGSSSG NQQCNWYGTL YPLCVTTTNG
210 220 230 240 250
WGWEDQRSCI ARSTCAAQPA PFGIVGSGSS TPVSSSSSSL SSSSVVSSIR
260 270 280 290 300
SSSSSSSSSV ATGNGLASLA DFPIGVAVAA SGGNADIFTS SARQNIVRAE
310 320 330 340 350
FNQITAENIM KMSYMYSGSN FSFTNSDRLV SWAAQNGQTV HGHALVWHPS
360 370 380 390 400
YQLPNWASDS NANFRQDFAR HIDTVAAHFA GQVKSWDVVN EALFDSADDP
410 420 430 440 450
DGRGSANGYR QSVFYRQFGG PEYIDEAFRR ARAADPTAEL YYNDFNTEEN
460 470 480 490 500
GAKTTALVNL VQRLLNNGVP IDGVGFQMHV MNDYPSIANI RQAMQKIVAL
510 520 530 540 550
SPTLKIKITE LDVRLNNPYD GNSSNDYTNR NDCAVSCAGL DRQKARYKEI
560 570 580 590 600
VQAYLEVVPP GRRGGITVWG IADPDSWLYT HQNLPDWPLL FNDNLQPKPA
610
YQGVVEALSG R
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 432 – 433 | RA → PR in CAA33469 (PubMed:2507868).Curated | 2 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X15429 Genomic DNA Translation: CAA33469.1 CP000934 Genomic DNA Translation: ACE85439.1 |
PIRi | S06047 |
Genome annotation databases
EnsemblBacteriai | ACE85439; ACE85439; CJA_2471 |
KEGGi | cja:CJA_2471 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X15429 Genomic DNA Translation: CAA33469.1 CP000934 Genomic DNA Translation: ACE85439.1 |
PIRi | S06047 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1CLX | X-ray | 1.80 | A/B/C/D | 265-611 | [»] | |
1E5N | X-ray | 3.20 | A/B | 264-611 | [»] | |
1E8R | NMR | - | A | 180-228 | [»] | |
1QLD | NMR | - | A | 180-228 | [»] | |
1W2P | X-ray | 1.45 | A/B | 265-611 | [»] | |
1W2V | X-ray | 1.55 | A/B | 265-611 | [»] | |
1W32 | X-ray | 1.20 | A/B | 265-611 | [»] | |
1W3H | X-ray | 1.50 | A/B | 265-611 | [»] | |
1XYS | X-ray | 2.50 | A/B | 265-611 | [»] | |
SMRi | P14768 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
STRINGi | 498211.CJA_2471 |
Protein family/group databases
CAZyi | CBM10, Carbohydrate-Binding Module Family 10 CBM2, Carbohydrate-Binding Module Family 2 GH10, Glycoside Hydrolase Family 10 |
Genome annotation databases
EnsemblBacteriai | ACE85439; ACE85439; CJA_2471 |
KEGGi | cja:CJA_2471 |
Phylogenomic databases
eggNOGi | COG3693, Bacteria |
HOGENOMi | CLU_029617_0_0_6 |
OMAi | GADDWPL |
Enzyme and pathway databases
UniPathwayi | UPA00114 |
Miscellaneous databases
EvolutionaryTracei | P14768 |
Family and domain databases
Gene3Di | 2.30.32.30, 1 hit 2.60.40.290, 1 hit |
InterProi | View protein in InterPro IPR001919, CBD2 IPR002883, CBM10/Dockerin_dom IPR036601, CBM10_sf IPR008965, CBM2/CBM3_carb-bd_dom_sf IPR012291, CBM2_carb-bd_dom_sf IPR018366, CBM2_CS IPR009031, CBM_fam10 IPR044846, GH10 IPR031158, GH10_AS IPR001000, GH10_dom IPR017853, Glycoside_hydrolase_SF |
PANTHERi | PTHR31490, PTHR31490, 1 hit |
Pfami | View protein in Pfam PF02013, CBM_10, 1 hit PF00553, CBM_2, 1 hit PF00331, Glyco_hydro_10, 1 hit |
PRINTSi | PR00134, GLHYDRLASE10 |
SMARTi | View protein in SMART SM00637, CBD_II, 1 hit SM01064, CBM_10, 1 hit SM00633, Glyco_10, 1 hit |
SUPFAMi | SSF49384, SSF49384, 1 hit SSF51445, SSF51445, 1 hit SSF57615, SSF57615, 1 hit |
PROSITEi | View protein in PROSITE PS51763, CBM10, 1 hit PS51173, CBM2, 1 hit PS00561, CBM2_A, 1 hit PS00591, GH10_1, 1 hit PS51760, GH10_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | XYNA_CELJU | |
Accessioni | P14768Primary (citable) accession number: P14768 Secondary accession number(s): B3PKK3 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 1, 1990 |
Last sequence update: | November 1, 1997 | |
Last modified: | February 23, 2022 | |
This is version 159 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencing, Reference proteomeDocuments
- Glycosyl hydrolases
Classification of glycosyl hydrolase families and list of entries - PATHWAY comments
Index of metabolic and biosynthesis pathways - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families