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UniProtKB - P14720 (DFRA_PETHY)
Protein
Dihydroflavonol 4-reductase
Gene
DFRA
Organism
Petunia hybrida (Petunia)
Status
Functioni
Bifunctional enzyme involved in flavonoid metabolism.
By similarityCatalytic activityi
: anthocyanin biosynthesis Pathwayi
This protein is involved in the pathway anthocyanin biosynthesis, which is part of Pigment biosynthesis.View all proteins of this organism that are known to be involved in the pathway anthocyanin biosynthesis and in Pigment biosynthesis.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 54 | NADPBy similarity | 1 | |
Binding sitei | 173 | NADPBy similarity | 1 |
GO - Molecular functioni
- dihydrokaempferol 4-reductase activity Source: UniProtKB-EC
- flavanone 4-reductase activity Source: UniProtKB-EC
GO - Biological processi
- anthocyanin-containing compound biosynthetic process Source: UniProtKB-UniPathway
Keywordsi
Molecular function | Oxidoreductase |
Biological process | Flavonoid biosynthesis |
Ligand | NADP |
Enzyme and pathway databases
UniPathwayi | UPA00009 |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:DFRA Synonyms:AN6 |
Organismi | Petunia hybrida (Petunia) |
Taxonomic identifieri | 4102 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › asterids › lamiids › Solanales › Solanaceae › Petunioideae › Petunia |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000215571 | 1 – 380 | Dihydroflavonol 4-reductaseAdd BLAST | 380 |
Family & Domainsi
Sequence similaritiesi
Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.Curated
Family and domain databases
InterProi | View protein in InterPro IPR001509, Epimerase_deHydtase IPR036291, NAD(P)-bd_dom_sf |
Pfami | View protein in Pfam PF01370, Epimerase, 1 hit |
SUPFAMi | SSF51735, SSF51735, 1 hit |
i Sequence
Sequence statusi: Complete.
P14720-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MASEAVHAPS PPVAVPTVCV TGAAGFIGSW LVMRLLERGY NVHATVRDPE
60 70 80 90 100
NKKKVKHLLE LPKADTNLTL WKADLTVEGS FDEAIQGCQG VFHVATPMDF
110 120 130 140 150
ESKDPENEVI KPTVRGMLSI IESCAKANTV KRLVFTSSAG TLDVQEQQKL
160 170 180 190 200
FYDQTSWSDL DFIYAKKMTG WMYFASKILA EKAAMEEAKK KNIDFISIIP
210 220 230 240 250
PLVVGPFITP TFPPSLITAL SLITGNEAHY CIIKQGQYVH LDDLCEAHIF
260 270 280 290 300
LYEHPKADGR FICSSHHAII YDVAKMVREK WPEYYVPTEF KGIDKDLPVV
310 320 330 340 350
SFSSKKLTDM GFQFKYTLED MYKGAIDTCR QKQLLPFSTR SAEDNGHNRE
360 370 380
AIAISAQNYA SGKENAPVAN HTEMLSNVEV
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 1 – 16 | MASEA…PVAVP → MPLHLRCSA (PubMed:2491667).CuratedAdd BLAST | 16 | |
Sequence conflicti | 71 | W → L in CAA33544 (PubMed:2491667).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X79723 Genomic DNA Translation: CAA56160.1 X15537 mRNA Translation: CAA33544.1 |
PIRi | S07463 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X79723 Genomic DNA Translation: CAA56160.1 X15537 mRNA Translation: CAA33544.1 |
PIRi | S07463 |
3D structure databases
SMRi | P14720 |
ModBasei | Search... |
Protocols and materials databases
ABCDi | P14720, 5 sequenced antibodies |
Enzyme and pathway databases
UniPathwayi | UPA00009 |
Family and domain databases
InterProi | View protein in InterPro IPR001509, Epimerase_deHydtase IPR036291, NAD(P)-bd_dom_sf |
Pfami | View protein in Pfam PF01370, Epimerase, 1 hit |
SUPFAMi | SSF51735, SSF51735, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | DFRA_PETHY | |
Accessioni | P14720Primary (citable) accession number: P14720 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 1, 1990 |
Last sequence update: | October 1, 1996 | |
Last modified: | December 2, 2020 | |
This is version 89 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Documents
- PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families