UniProtKB - P14543 (NID1_HUMAN)
Nidogen-1
NID1
Functioni
Sulfated glycoprotein widely distributed in basement membranes and tightly associated with laminin. Also binds to collagen IV and perlecan. It probably has a role in cell-extracellular matrix interactions.
GO - Molecular functioni
- calcium ion binding Source: InterPro
- collagen binding Source: BHF-UCL
- extracellular matrix structural constituent Source: BHF-UCL
- laminin-1 binding Source: Ensembl
- laminin binding Source: BHF-UCL
- proteoglycan binding Source: BHF-UCL
GO - Biological processi
- basement membrane organization Source: BHF-UCL
- cell-matrix adhesion Source: Ensembl
- glomerular basement membrane development Source: Ensembl
- positive regulation of cell adhesion Source: ComplexPortal
- positive regulation of cell-substrate adhesion Source: Ensembl
- positive regulation of integrin-mediated signaling pathway Source: ComplexPortal
- positive regulation of muscle cell differentiation Source: ComplexPortal
- regulation of basement membrane organization Source: ComplexPortal
Keywordsi
Biological process | Cell adhesion |
Ligand | Calcium |
Enzyme and pathway databases
PathwayCommonsi | P14543 |
Reactomei | R-HSA-1474228, Degradation of the extracellular matrix R-HSA-3000157, Laminin interactions |
SignaLinki | P14543 |
SIGNORi | P14543 |
Names & Taxonomyi
Protein namesi | Recommended name: Nidogen-1Short name: NID-1 Alternative name(s): Entactin |
Gene namesi | Name:NID1 Synonyms:NID |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:7821, NID1 |
MIMi | 131390, gene |
neXtProti | NX_P14543 |
VEuPathDBi | HostDB:ENSG00000116962 |
Subcellular locationi
Extracellular region or secreted
Extracellular region or secreted
- extracellular exosome Source: UniProtKB
- extracellular region Source: Reactome
Plasma Membrane
- plasma membrane Source: GO_Central
Other locations
- basement membrane Source: BHF-UCL
- collagen-containing extracellular matrix Source: UniProtKB
- protein complex involved in cell-matrix adhesion Source: ComplexPortal
Keywords - Cellular componenti
Basement membrane, Extracellular matrix, SecretedPathology & Biotechi
Organism-specific databases
DisGeNETi | 4811 |
MalaCardsi | NID1 |
OpenTargetsi | ENSG00000116962 |
Orphaneti | 269215, Isolated Dandy-Walker malformation without hydrocephalus |
PharmGKBi | PA31625 |
Miscellaneous databases
Pharosi | P14543, Tbio |
Chemistry databases
DrugBanki | DB00013, Urokinase |
Genetic variation databases
BioMutai | NID1 |
DMDMi | 251757450 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 28 | Add BLAST | 28 | |
ChainiPRO_0000007669 | 29 – 1247 | Nidogen-1Add BLAST | 1219 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 289 | SulfotyrosineSequence analysis | 1 | |
Modified residuei | 296 | SulfotyrosineSequence analysis | 1 | |
Disulfide bondi | 390 ↔ 403 | By similarity | ||
Disulfide bondi | 397 ↔ 412 | By similarity | ||
Disulfide bondi | 411 ↔ 618 | By similarity | ||
Disulfide bondi | 414 ↔ 425 | By similarity | ||
Disulfide bondi | 672 ↔ 685 | By similarity | ||
Disulfide bondi | 679 ↔ 695 | By similarity | ||
Disulfide bondi | 697 ↔ 708 | By similarity | ||
Disulfide bondi | 714 ↔ 727 | By similarity | ||
Disulfide bondi | 721 ↔ 736 | By similarity | ||
Disulfide bondi | 738 ↔ 750 | By similarity | ||
Disulfide bondi | 762 ↔ 777 | By similarity | ||
Disulfide bondi | 769 ↔ 787 | By similarity | ||
Disulfide bondi | 789 ↔ 800 | By similarity | ||
Disulfide bondi | 806 ↔ 817 | By similarity | ||
Disulfide bondi | 811 ↔ 826 | By similarity | ||
Disulfide bondi | 828 ↔ 839 | By similarity | ||
Disulfide bondi | 849 ↔ 878 | By similarity | ||
Disulfide bondi | 889 ↔ 896 | By similarity | ||
Disulfide bondi | 898 ↔ 919 | By similarity | ||
Glycosylationi | 922 | O-linked (GalNAc...) threonineSequence analysis | 1 | |
Glycosylationi | 935 | O-linked (GalNAc...) threonineSequence analysis | 1 | |
Disulfide bondi | 1212 ↔ 1223 | By similarity | ||
Disulfide bondi | 1219 ↔ 1232 | By similarity | ||
Disulfide bondi | 1234 ↔ 1243 | By similarity |
Post-translational modificationi
Keywords - PTMi
Disulfide bond, Glycoprotein, SulfationProteomic databases
EPDi | P14543 |
jPOSTi | P14543 |
MassIVEi | P14543 |
MaxQBi | P14543 |
PaxDbi | P14543 |
PeptideAtlasi | P14543 |
PRIDEi | P14543 |
ProteomicsDBi | 53056 [P14543-1] 53057 [P14543-2] |
PTM databases
GlyGeni | P14543, 10 sites, 4 O-linked glycans (9 sites) |
iPTMneti | P14543 |
PhosphoSitePlusi | P14543 |
Expressioni
Gene expression databases
Bgeei | ENSG00000116962, Expressed in endometrium and 221 other tissues |
Genevisiblei | P14543, HS |
Organism-specific databases
HPAi | ENSG00000116962, Tissue enhanced (placenta) |
Interactioni
Subunit structurei
Interacts with FBLN1 and LGALS3BP (By similarity).
Interacts with PLXDC1.
By similarity1 PublicationGO - Molecular functioni
- laminin-1 binding Source: Ensembl
- laminin binding Source: BHF-UCL
- proteoglycan binding Source: BHF-UCL
Protein-protein interaction databases
BioGRIDi | 110876, 26 interactors |
ComplexPortali | CPX-1265, Laminin111-nidogen complex CPX-1282, Laminin211-nidogen complex CPX-1285, Laminin221-nidogen complex |
IntActi | P14543, 18 interactors |
MINTi | P14543 |
STRINGi | 9606.ENSP00000264187 |
Miscellaneous databases
RNActi | P14543, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 106 – 268 | NIDOPROSITE-ProRule annotationAdd BLAST | 163 | |
Domaini | 386 – 426 | EGF-like 1PROSITE-ProRule annotationAdd BLAST | 41 | |
Domaini | 430 – 667 | Nidogen G2 beta-barrelPROSITE-ProRule annotationAdd BLAST | 238 | |
Domaini | 668 – 709 | EGF-like 2PROSITE-ProRule annotationAdd BLAST | 42 | |
Domaini | 710 – 751 | EGF-like 3; calcium-bindingPROSITE-ProRule annotationAdd BLAST | 42 | |
Domaini | 758 – 801 | EGF-like 4PROSITE-ProRule annotationAdd BLAST | 44 | |
Domaini | 802 – 840 | EGF-like 5; calcium-bindingPROSITE-ProRule annotationAdd BLAST | 39 | |
Domaini | 846 – 919 | Thyroglobulin type-1PROSITE-ProRule annotationAdd BLAST | 74 | |
Repeati | 990 – 1032 | LDL-receptor class B 1Add BLAST | 43 | |
Repeati | 1033 – 1075 | LDL-receptor class B 2Add BLAST | 43 | |
Repeati | 1076 – 1120 | LDL-receptor class B 3Add BLAST | 45 | |
Repeati | 1121 – 1162 | LDL-receptor class B 4Add BLAST | 42 | |
Domaini | 1208 – 1244 | EGF-like 6PROSITE-ProRule annotationAdd BLAST | 37 |
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 702 – 704 | Cell attachment site | 3 |
Keywords - Domaini
EGF-like domain, Repeat, SignalPhylogenomic databases
eggNOGi | KOG1214, Eukaryota |
GeneTreei | ENSGT00940000156318 |
HOGENOMi | CLU_003163_1_0_1 |
InParanoidi | P14543 |
OMAi | HVSRLQF |
OrthoDBi | 95286at2759 |
PhylomeDBi | P14543 |
TreeFami | TF320666 |
Family and domain databases
CDDi | cd00255, nidG2, 1 hit cd00191, TY, 1 hit |
Gene3Di | 2.120.10.30, 1 hit 2.40.155.10, 1 hit 4.10.800.10, 1 hit |
InterProi | View protein in InterPro IPR011042, 6-blade_b-propeller_TolB-like IPR026823, cEGF IPR001881, EGF-like_Ca-bd_dom IPR000742, EGF-like_dom IPR000152, EGF-type_Asp/Asn_hydroxyl_site IPR018097, EGF_Ca-bd_CS IPR024731, EGF_dom IPR006605, G2_nidogen/fibulin_G2F IPR009017, GFP IPR009030, Growth_fac_rcpt_cys_sf IPR000033, LDLR_classB_rpt IPR003886, NIDO_dom IPR000716, Thyroglobulin_1 IPR036857, Thyroglobulin_1_sf |
Pfami | View protein in Pfam PF12662, cEGF, 1 hit PF12947, EGF_3, 2 hits PF07645, EGF_CA, 1 hit PF07474, G2F, 1 hit PF00058, Ldl_recept_b, 3 hits PF06119, NIDO, 1 hit PF00086, Thyroglobulin_1, 1 hit |
SMARTi | View protein in SMART SM00181, EGF, 6 hits SM00179, EGF_CA, 4 hits SM00682, G2F, 1 hit SM00135, LY, 5 hits SM00539, NIDO, 1 hit SM00211, TY, 1 hit |
SUPFAMi | SSF54511, SSF54511, 1 hit SSF57184, SSF57184, 2 hits SSF57610, SSF57610, 1 hit |
PROSITEi | View protein in PROSITE PS00010, ASX_HYDROXYL, 3 hits PS00022, EGF_1, 1 hit PS01186, EGF_2, 5 hits PS50026, EGF_3, 5 hits PS01187, EGF_CA, 2 hits PS51120, LDLRB, 4 hits PS51220, NIDO, 1 hit PS50993, NIDOGEN_G2, 1 hit PS00484, THYROGLOBULIN_1_1, 1 hit PS51162, THYROGLOBULIN_1_2, 1 hit |
s (2)i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketThis isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MLASSSRIRA AWTRALLLPL LLAGPVGCLS RQELFPFGPG QGDLELEDGD
60 70 80 90 100
DFVSPALELS GALRFYDRSD IDAVYVTTNG IIATSEPPAK ESHPGLFPPT
110 120 130 140 150
FGAVAPFLAD LDTTDGLGKV YYREDLSPSI TQRAAECVHR GFPEISFQPS
160 170 180 190 200
SAVVVTWESV APYQGPSRDP DQKGKRNTFQ AVLASSDSSS YAIFLYPEDG
210 220 230 240 250
LQFHTTFSKK ENNQVPAVVA FSQGSVGFLW KSNGAYNIFA NDRESVENLA
260 270 280 290 300
KSSNSGQQGV WVFEIGSPAT TNGVVPADVI LGTEDGAEYD DEDEDYDLAT
310 320 330 340 350
TRLGLEDVGT TPFSYKALRR GGADTYSVPS VLSPRRAATE RPLGPPTERT
360 370 380 390 400
RSFQLAVETF HQQHPQVIDV DEVEETGVVF SYNTDSRQTC ANNRHQCSVH
410 420 430 440 450
AECRDYATGF CCSCVAGYTG NGRQCVAEGS PQRVNGKVKG RIFVGSSQVP
460 470 480 490 500
IVFENTDLHS YVVMNHGRSY TAISTIPETV GYSLLPLAPV GGIIGWMFAV
510 520 530 540 550
EQDGFKNGFS ITGGEFTRQA EVTFVGHPGN LVIKQRFSGI DEHGHLTIDT
560 570 580 590 600
ELEGRVPQIP FGSSVHIEPY TELYHYSTSV ITSSSTREYT VTEPERDGAS
610 620 630 640 650
PSRIYTYQWR QTITFQECVH DDSRPALPST QQLSVDSVFV LYNQEEKILR
660 670 680 690 700
YALSNSIGPV REGSPDALQN PCYIGTHGCD TNAACRPGPR TQFTCECSIG
710 720 730 740 750
FRGDGRTCYD IDECSEQPSV CGSHTICNNH PGTFRCECVE GYQFSDEGTC
760 770 780 790 800
VAVVDQRPIN YCETGLHNCD IPQRAQCIYT GGSSYTCSCL PGFSGDGQAC
810 820 830 840 850
QDVDECQPSR CHPDAFCYNT PGSFTCQCKP GYQGDGFRCV PGEVEKTRCQ
860 870 880 890 900
HEREHILGAA GATDPQRPIP PGLFVPECDA HGHYAPTQCH GSTGYCWCVD
910 920 930 940 950
RDGREVEGTR TRPGMTPPCL STVAPPIHQG PAVPTAVIPL PPGTHLLFAQ
960 970 980 990 1000
TGKIERLPLE GNTMRKTEAK AFLHVPAKVI IGLAFDCVDK MVYWTDITEP
1010 1020 1030 1040 1050
SIGRASLHGG EPTTIIRQDL GSPEGIAVDH LGRNIFWTDS NLDRIEVAKL
1060 1070 1080 1090 1100
DGTQRRVLFE TDLVNPRGIV TDSVRGNLYW TDWNRDNPKI ETSYMDGTNR
1110 1120 1130 1140 1150
RILVQDDLGL PNGLTFDAFS SQLCWVDAGT NRAECLNPSQ PSRRKALEGL
1160 1170 1180 1190 1200
QYPFAVTSYG KNLYFTDWKM NSVVALDLAI SKETDAFQPH KQTRLYGITT
1210 1220 1230 1240
ALSQCPQGHN YCSVNNGGCT HLCLATPGSR TCRCPDNTLG VDCIEQK
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 33 – 34 | EL → SS in CAA57709 (PubMed:7557988).Curated | 2 | |
Sequence conflicti | 37 – 42 | FGPGQG → SAPDR in CAA57709 (PubMed:7557988).Curated | 6 | |
Sequence conflicti | 653 | L → F in AAA59932 (PubMed:2574658).Curated | 1 | |
Sequence conflicti | 653 | L → F in CAA57709 (PubMed:7557988).Curated | 1 | |
Sequence conflicti | 1115 | T → H in AAA59932 (PubMed:2574658).Curated | 1 | |
Sequence conflicti | 1115 | T → H in CAA57709 (PubMed:7557988).Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_055760 | 31 | R → L. Corresponds to variant dbSNP:rs2071529EnsemblClinVar. | 1 | |
Natural variantiVAR_058123 | 60 | S → R1 PublicationCorresponds to variant dbSNP:rs17857302Ensembl. | 1 | |
Natural variantiVAR_024264 | 246 | V → I4 PublicationsCorresponds to variant dbSNP:rs10733133Ensembl. | 1 | |
Natural variantiVAR_055761 | 302 | R → H. Corresponds to variant dbSNP:rs16833183EnsemblClinVar. | 1 | |
Natural variantiVAR_055762 | 335 | R → H. Corresponds to variant dbSNP:rs34406281EnsemblClinVar. | 1 | |
Natural variantiVAR_055763 | 387 | R → H. Corresponds to variant dbSNP:rs16833154EnsemblClinVar. | 1 | |
Natural variantiVAR_021904 | 669 | Q → R. Corresponds to variant dbSNP:rs3738534EnsemblClinVar. | 1 | |
Natural variantiVAR_058124 | 807 | Q → H1 PublicationCorresponds to variant dbSNP:rs3738531Ensembl. | 1 | |
Natural variantiVAR_055764 | 970 | K → E. Corresponds to variant dbSNP:rs16833060EnsemblClinVar. | 1 | |
Natural variantiVAR_035835 | 1036 | F → S in a colorectal cancer sample; somatic mutation. 1 Publication | 1 | |
Natural variantiVAR_055765 | 1163 | L → V. Corresponds to variant dbSNP:rs16833032EnsemblClinVar. | 1 | |
Natural variantiVAR_055766 | 1226 | T → I. Corresponds to variant dbSNP:rs6662744EnsemblClinVar. | 1 | |
Natural variantiVAR_058125 | 1246 | Q → R3 PublicationsCorresponds to variant dbSNP:rs3213190Ensembl. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_017254 | 710 – 842 | Missing in isoform 2. 2 PublicationsAdd BLAST | 133 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M30269 mRNA Translation: AAA59932.1 X82245 , X84819, X84820, X84821, X84822, X84823, X84824, X84825, X84826, X84827, X84828, X84829, X84830, X84831, X84832, X84833, X84834, X84835, X84836, X84837 Genomic DNA Translation: CAA57709.1 AL122018 Genomic DNA No translation available. AL139161 Genomic DNA No translation available. BC045606 mRNA Translation: AAH45606.1 AB209448 mRNA Translation: BAD92685.1 M27445 mRNA Translation: AAA57261.1 |
CCDSi | CCDS1608.1 [P14543-1] |
PIRi | A33322, MMHUND |
RefSeqi | NP_002499.2, NM_002508.2 [P14543-1] |
Genome annotation databases
Ensembli | ENST00000264187.7; ENSP00000264187.6; ENSG00000116962.15 ENST00000366595.7; ENSP00000355554.3; ENSG00000116962.15 [P14543-2] |
GeneIDi | 4811 |
KEGGi | hsa:4811 |
MANE-Selecti | ENST00000264187.7; ENSP00000264187.6; NM_002508.3; NP_002499.2 |
UCSCi | uc001hxo.4, human [P14543-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M30269 mRNA Translation: AAA59932.1 X82245 , X84819, X84820, X84821, X84822, X84823, X84824, X84825, X84826, X84827, X84828, X84829, X84830, X84831, X84832, X84833, X84834, X84835, X84836, X84837 Genomic DNA Translation: CAA57709.1 AL122018 Genomic DNA No translation available. AL139161 Genomic DNA No translation available. BC045606 mRNA Translation: AAH45606.1 AB209448 mRNA Translation: BAD92685.1 M27445 mRNA Translation: AAA57261.1 |
CCDSi | CCDS1608.1 [P14543-1] |
PIRi | A33322, MMHUND |
RefSeqi | NP_002499.2, NM_002508.2 [P14543-1] |
3D structure databases
AlphaFoldDBi | P14543 |
SMRi | P14543 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 110876, 26 interactors |
ComplexPortali | CPX-1265, Laminin111-nidogen complex CPX-1282, Laminin211-nidogen complex CPX-1285, Laminin221-nidogen complex |
IntActi | P14543, 18 interactors |
MINTi | P14543 |
STRINGi | 9606.ENSP00000264187 |
Chemistry databases
DrugBanki | DB00013, Urokinase |
PTM databases
GlyGeni | P14543, 10 sites, 4 O-linked glycans (9 sites) |
iPTMneti | P14543 |
PhosphoSitePlusi | P14543 |
Genetic variation databases
BioMutai | NID1 |
DMDMi | 251757450 |
Proteomic databases
EPDi | P14543 |
jPOSTi | P14543 |
MassIVEi | P14543 |
MaxQBi | P14543 |
PaxDbi | P14543 |
PeptideAtlasi | P14543 |
PRIDEi | P14543 |
ProteomicsDBi | 53056 [P14543-1] 53057 [P14543-2] |
Protocols and materials databases
Antibodypediai | 4102, 426 antibodies from 34 providers |
DNASUi | 4811 |
Genome annotation databases
Ensembli | ENST00000264187.7; ENSP00000264187.6; ENSG00000116962.15 ENST00000366595.7; ENSP00000355554.3; ENSG00000116962.15 [P14543-2] |
GeneIDi | 4811 |
KEGGi | hsa:4811 |
MANE-Selecti | ENST00000264187.7; ENSP00000264187.6; NM_002508.3; NP_002499.2 |
UCSCi | uc001hxo.4, human [P14543-1] |
Organism-specific databases
CTDi | 4811 |
DisGeNETi | 4811 |
GeneCardsi | NID1 |
HGNCi | HGNC:7821, NID1 |
HPAi | ENSG00000116962, Tissue enhanced (placenta) |
MalaCardsi | NID1 |
MIMi | 131390, gene |
neXtProti | NX_P14543 |
OpenTargetsi | ENSG00000116962 |
Orphaneti | 269215, Isolated Dandy-Walker malformation without hydrocephalus |
PharmGKBi | PA31625 |
VEuPathDBi | HostDB:ENSG00000116962 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG1214, Eukaryota |
GeneTreei | ENSGT00940000156318 |
HOGENOMi | CLU_003163_1_0_1 |
InParanoidi | P14543 |
OMAi | HVSRLQF |
OrthoDBi | 95286at2759 |
PhylomeDBi | P14543 |
TreeFami | TF320666 |
Enzyme and pathway databases
PathwayCommonsi | P14543 |
Reactomei | R-HSA-1474228, Degradation of the extracellular matrix R-HSA-3000157, Laminin interactions |
SignaLinki | P14543 |
SIGNORi | P14543 |
Miscellaneous databases
BioGRID-ORCSi | 4811, 12 hits in 1074 CRISPR screens |
ChiTaRSi | NID1, human |
GeneWikii | Entactin |
GenomeRNAii | 4811 |
Pharosi | P14543, Tbio |
PROi | PR:P14543 |
RNActi | P14543, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000116962, Expressed in endometrium and 221 other tissues |
Genevisiblei | P14543, HS |
Family and domain databases
CDDi | cd00255, nidG2, 1 hit cd00191, TY, 1 hit |
Gene3Di | 2.120.10.30, 1 hit 2.40.155.10, 1 hit 4.10.800.10, 1 hit |
InterProi | View protein in InterPro IPR011042, 6-blade_b-propeller_TolB-like IPR026823, cEGF IPR001881, EGF-like_Ca-bd_dom IPR000742, EGF-like_dom IPR000152, EGF-type_Asp/Asn_hydroxyl_site IPR018097, EGF_Ca-bd_CS IPR024731, EGF_dom IPR006605, G2_nidogen/fibulin_G2F IPR009017, GFP IPR009030, Growth_fac_rcpt_cys_sf IPR000033, LDLR_classB_rpt IPR003886, NIDO_dom IPR000716, Thyroglobulin_1 IPR036857, Thyroglobulin_1_sf |
Pfami | View protein in Pfam PF12662, cEGF, 1 hit PF12947, EGF_3, 2 hits PF07645, EGF_CA, 1 hit PF07474, G2F, 1 hit PF00058, Ldl_recept_b, 3 hits PF06119, NIDO, 1 hit PF00086, Thyroglobulin_1, 1 hit |
SMARTi | View protein in SMART SM00181, EGF, 6 hits SM00179, EGF_CA, 4 hits SM00682, G2F, 1 hit SM00135, LY, 5 hits SM00539, NIDO, 1 hit SM00211, TY, 1 hit |
SUPFAMi | SSF54511, SSF54511, 1 hit SSF57184, SSF57184, 2 hits SSF57610, SSF57610, 1 hit |
PROSITEi | View protein in PROSITE PS00010, ASX_HYDROXYL, 3 hits PS00022, EGF_1, 1 hit PS01186, EGF_2, 5 hits PS50026, EGF_3, 5 hits PS01187, EGF_CA, 2 hits PS51120, LDLRB, 4 hits PS51220, NIDO, 1 hit PS50993, NIDOGEN_G2, 1 hit PS00484, THYROGLOBULIN_1_1, 1 hit PS51162, THYROGLOBULIN_1_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | NID1_HUMAN | |
Accessioni | P14543Primary (citable) accession number: P14543 Secondary accession number(s): Q14942 Q86XD7 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 1, 1990 |
Last sequence update: | July 7, 2009 | |
Last modified: | May 25, 2022 | |
This is version 226 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome 1
Human chromosome 1: entries, gene names and cross-references to MIM - Human entries with genetic variants
List of human entries with genetic variants - Human variants curated from literature reports
Index of human variants curated from literature reports - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot