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Protein

Pupal cuticle protein

Gene

Pcp

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Component of the cuticle of the pupa of fruit fly.

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Pupal cuticle protein
Gene namesi
Name:Pcp
ORF Names:CG3440
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2L

Organism-specific databases

FlyBaseiFBgn0003046 Pcp

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cuticle

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 15Sequence analysisAdd BLAST15
ChainiPRO_000000639716 – 184Pupal cuticle proteinAdd BLAST169

Proteomic databases

PaxDbiP14484
PRIDEiP14484

Expressioni

Developmental stagei

Expressed throughout both the fourth and the fifth larval instars.

Gene expression databases

BgeeiFBgn0003046 Expressed in 12 organ(s), highest expression level in larva
GenevisibleiP14484 DM

Structurei

3D structure databases

SMRiP14484
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini42 – 103Chitin-binding type R&RPROSITE-ProRule annotationAdd BLAST62

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410KC0S Eukaryota
ENOG4110MQM LUCA
GeneTreeiENSGT00900000141325
InParanoidiP14484
OMAiIRTHPYQ
OrthoDBiEOG091G0KRD
PhylomeDBiP14484

Family and domain databases

InterProiView protein in InterPro
IPR031311 CHIT_BIND_RR_consensus
IPR000618 Insect_cuticle
PfamiView protein in Pfam
PF00379 Chitin_bind_4, 1 hit
PRINTSiPR00947 CUTICLE
PROSITEiView protein in PROSITE
PS00233 CHIT_BIND_RR_1, 1 hit
PS51155 CHIT_BIND_RR_2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P14484-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MYLLVNFIVA LAVLQVQAGS SYIPDSDRNT RTLQNDLQVE RDGKYRYAYE
60 70 80 90 100
TSNGISASQE GLGGVAVQGG SSYTSPEGEV ISVNYVADEF GYHPVGAHIP
110 120 130 140 150
QVPDYILRSL EYIRTHPYQI KDYYTGELKT VEHDAAAFNV YTRNIQDHTI
160 170 180
PQSRPSTTPK TIYLTHPPTT TSRPLRQRRA LPTH
Length:184
Mass (Da):20,633
Last modified:January 1, 1990 - v1
Checksum:i4493B893F61329C2
GO

Sequence cautioni

The sequence ABX00770 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti4L → LQ in AAA28564 (PubMed:3079672).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J02527 Genomic DNA Translation: AAA28564.1
AE014134 Genomic DNA Translation: AAF52475.1
BT031148 mRNA Translation: ABX00770.1 Different initiation.
PIRiB24787 UCFFPM
RefSeqiNP_476673.1, NM_057325.3

Genome annotation databases

EnsemblMetazoaiFBtr0079388; FBpp0079016; FBgn0003046
GeneIDi33985
KEGGidme:Dmel_CG3440

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J02527 Genomic DNA Translation: AAA28564.1
AE014134 Genomic DNA Translation: AAF52475.1
BT031148 mRNA Translation: ABX00770.1 Different initiation.
PIRiB24787 UCFFPM
RefSeqiNP_476673.1, NM_057325.3

3D structure databases

SMRiP14484
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PaxDbiP14484
PRIDEiP14484

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0079388; FBpp0079016; FBgn0003046
GeneIDi33985
KEGGidme:Dmel_CG3440

Organism-specific databases

CTDi18543
FlyBaseiFBgn0003046 Pcp

Phylogenomic databases

eggNOGiENOG410KC0S Eukaryota
ENOG4110MQM LUCA
GeneTreeiENSGT00900000141325
InParanoidiP14484
OMAiIRTHPYQ
OrthoDBiEOG091G0KRD
PhylomeDBiP14484

Miscellaneous databases

GenomeRNAii33985
PROiPR:P14484

Gene expression databases

BgeeiFBgn0003046 Expressed in 12 organ(s), highest expression level in larva
GenevisibleiP14484 DM

Family and domain databases

InterProiView protein in InterPro
IPR031311 CHIT_BIND_RR_consensus
IPR000618 Insect_cuticle
PfamiView protein in Pfam
PF00379 Chitin_bind_4, 1 hit
PRINTSiPR00947 CUTICLE
PROSITEiView protein in PROSITE
PS00233 CHIT_BIND_RR_1, 1 hit
PS51155 CHIT_BIND_RR_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiCUPP_DROME
AccessioniPrimary (citable) accession number: P14484
Secondary accession number(s): A8WHK2, Q9VM52
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: January 1, 1990
Last modified: September 12, 2018
This is version 129 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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