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UniProtKB - P14318 (MP20_DROME)
Protein
Muscle-specific protein 20
Gene
Mp20
Organism
Drosophila melanogaster (Fruit fly)
Status
Functioni
GO - Biological processi
- myoblast fusion Source: FlyBase
- regulation of myoblast fusion Source: FlyBase
Keywordsi
Molecular function | Muscle protein |
Enzyme and pathway databases
SignaLinki | P14318 |
Names & Taxonomyi
Protein namesi | Recommended name: Muscle-specific protein 20 |
Gene namesi | Name:Mp20 Synonyms:Tpn ORF Names:CG4696 |
Organismi | Drosophila melanogaster (Fruit fly) |
Taxonomic identifieri | 7227 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora › |
Proteomesi |
|
Organism-specific databases
FlyBasei | FBgn0002789, Mp20 |
VEuPathDBi | VectorBase:FBgn0002789 |
Subcellular locationi
Cytoskeleton
- cytoskeleton Source: GO_Central
Other locations
- cytoplasm Source: FlyBase
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000204779 | 1 – 184 | Muscle-specific protein 20Add BLAST | 184 |
Proteomic databases
PaxDbi | P14318 |
PRIDEi | P14318 |
Expressioni
Tissue specificityi
Found in synchronous muscle; not found in asynchronous indirect flight muscle.1 Publication
Gene expression databases
Bgeei | FBgn0002789, Expressed in oviduct (Drosophila) and 40 other tissues |
Genevisiblei | P14318, DM |
Interactioni
Protein-protein interaction databases
BioGRIDi | 62231, 8 interactors |
DIPi | DIP-18096N |
IntActi | P14318, 3 interactors |
STRINGi | 7227.FBpp0086858 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 17 – 122 | Calponin-homology (CH)PROSITE-ProRule annotationAdd BLAST | 106 | |
Repeati | 157 – 181 | Calponin-likeAdd BLAST | 25 |
Sequence similaritiesi
Belongs to the calponin family.Curated
Phylogenomic databases
eggNOGi | KOG2046, Eukaryota |
GeneTreei | ENSGT00940000170006 |
HOGENOMi | CLU_055232_1_1_1 |
InParanoidi | P14318 |
OMAi | EYGYMKG |
OrthoDBi | 861989at2759 |
PhylomeDBi | P14318 |
Family and domain databases
CDDi | cd00014, CH, 1 hit |
Gene3Di | 1.10.418.10, 1 hit |
InterProi | View protein in InterPro IPR000557, Calponin_repeat IPR001715, CH-domain IPR036872, CH_dom_sf IPR003096, SM22_calponin |
Pfami | View protein in Pfam PF00402, Calponin, 1 hit PF00307, CH, 1 hit |
PRINTSi | PR00888, SM22CALPONIN |
SMARTi | View protein in SMART SM00033, CH, 1 hit |
SUPFAMi | SSF47576, SSF47576, 1 hit |
PROSITEi | View protein in PROSITE PS01052, CALPONIN_1, 1 hit PS51122, CALPONIN_2, 1 hit PS50021, CH, 1 hit |
i Sequence
Sequence statusi: Complete.
P14318-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSLERAVRAK IASKRNPEMD KEAQEWIEAI IAEKFPAGQS YEDVLKDGQV
60 70 80 90 100
LCKLINVLSP NAVPKVNSSG GQFKFMENIN NFQKALKEYG VPDIDVFQTV
110 120 130 140 150
DLYEKKDIAN VTNTIFALGR ATYKHADFKG PFLGPKPADE CKRDFTEEQL
160 170 180
KAGQTIVGLQ AGSNKGATQA GQNLGAGRKI LLGK
Sequence cautioni
The sequence ABE01209 differs from that shown. Reason: Erroneous initiation.Curated
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 13 | S → G in CAA68746 (PubMed:2537318).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Y00795 Genomic DNA Translation: CAA68746.1 AE013599 Genomic DNA Translation: AAF58396.1 AE013599 Genomic DNA Translation: AAM68603.1 AY071496 mRNA Translation: AAL49118.1 BT024979 mRNA Translation: ABE01209.1 Different initiation. |
PIRi | A30128 |
RefSeqi | NP_001014522.2, NM_001014522.2 NP_476643.1, NM_057295.4 |
Genome annotation databases
EnsemblMetazoai | FBtr0087745; FBpp0086858; FBgn0002789 |
GeneIDi | 36468 |
KEGGi | dme:Dmel_CG4696 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Y00795 Genomic DNA Translation: CAA68746.1 AE013599 Genomic DNA Translation: AAF58396.1 AE013599 Genomic DNA Translation: AAM68603.1 AY071496 mRNA Translation: AAL49118.1 BT024979 mRNA Translation: ABE01209.1 Different initiation. |
PIRi | A30128 |
RefSeqi | NP_001014522.2, NM_001014522.2 NP_476643.1, NM_057295.4 |
3D structure databases
AlphaFoldDBi | P14318 |
SMRi | P14318 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 62231, 8 interactors |
DIPi | DIP-18096N |
IntActi | P14318, 3 interactors |
STRINGi | 7227.FBpp0086858 |
Proteomic databases
PaxDbi | P14318 |
PRIDEi | P14318 |
Protocols and materials databases
DNASUi | 36468 |
Genome annotation databases
EnsemblMetazoai | FBtr0087745; FBpp0086858; FBgn0002789 |
GeneIDi | 36468 |
KEGGi | dme:Dmel_CG4696 |
Organism-specific databases
CTDi | 36468 |
FlyBasei | FBgn0002789, Mp20 |
VEuPathDBi | VectorBase:FBgn0002789 |
Phylogenomic databases
eggNOGi | KOG2046, Eukaryota |
GeneTreei | ENSGT00940000170006 |
HOGENOMi | CLU_055232_1_1_1 |
InParanoidi | P14318 |
OMAi | EYGYMKG |
OrthoDBi | 861989at2759 |
PhylomeDBi | P14318 |
Enzyme and pathway databases
SignaLinki | P14318 |
Miscellaneous databases
BioGRID-ORCSi | 36468, 0 hits in 3 CRISPR screens |
ChiTaRSi | Mp20, fly |
GenomeRNAii | 36468 |
PROi | PR:P14318 |
Gene expression databases
Bgeei | FBgn0002789, Expressed in oviduct (Drosophila) and 40 other tissues |
Genevisiblei | P14318, DM |
Family and domain databases
CDDi | cd00014, CH, 1 hit |
Gene3Di | 1.10.418.10, 1 hit |
InterProi | View protein in InterPro IPR000557, Calponin_repeat IPR001715, CH-domain IPR036872, CH_dom_sf IPR003096, SM22_calponin |
Pfami | View protein in Pfam PF00402, Calponin, 1 hit PF00307, CH, 1 hit |
PRINTSi | PR00888, SM22CALPONIN |
SMARTi | View protein in SMART SM00033, CH, 1 hit |
SUPFAMi | SSF47576, SSF47576, 1 hit |
PROSITEi | View protein in PROSITE PS01052, CALPONIN_1, 1 hit PS51122, CALPONIN_2, 1 hit PS50021, CH, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | MP20_DROME | |
Accessioni | P14318Primary (citable) accession number: P14318 Secondary accession number(s): A4UZF7, Q1WWC7, Q9V6M7 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 1, 1990 |
Last sequence update: | August 2, 2002 | |
Last modified: | May 25, 2022 | |
This is version 176 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Drosophila annotation project |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Drosophila
Drosophila: entries, gene names and cross-references to FlyBase - SIMILARITY comments
Index of protein domains and families