UniProtKB - P14291 (RED1_YEAST)
Protein
Protein RED1
Gene
RED1
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
Probable constituent of the synaptonemal complex during meiosis. May interact with HOP1. Required for meiosis I chromosome segregation.
GO - Molecular functioni
- chromatin DNA binding Source: SGD
- identical protein binding Source: IntAct
- structural molecule activity Source: SGD
GO - Biological processi
- meiotic recombination checkpoint Source: SGD
- positive regulation of catalytic activity Source: SGD
- reciprocal meiotic recombination Source: InterPro
- sporulation resulting in formation of a cellular spore Source: UniProtKB-KW
- synaptonemal complex assembly Source: SGD
Keywordsi
Biological process | Meiosis, Sporulation |
Names & Taxonomyi
Protein namesi | Recommended name: Protein RED1Alternative name(s): Reductional division protein 1 |
Gene namesi | Name:RED1 Ordered Locus Names:YLR263W ORF Names:L8479.6 |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
SGDi | S000004253, RED1 |
VEuPathDBi | FungiDB:YLR263W |
Subcellular locationi
Nucleus
Nucleus
- lateral element Source: SGD
Keywords - Cellular componenti
NucleusPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000097234 | 1 – 827 | Protein RED1Add BLAST | 827 |
Proteomic databases
PaxDbi | P14291 |
PRIDEi | P14291 |
PTM databases
iPTMneti | P14291 |
Expressioni
Developmental stagei
Meiosis-specific.
Interactioni
Binary interactionsi
Hide detailsP14291
With | #Exp. | IntAct |
---|---|---|
HOP1 [P20050] | 3 | EBI-14909,EBI-3768303 |
itself | 3 | EBI-14909,EBI-14909 |
SMT3 [Q12306] | 9 | EBI-14909,EBI-17490 |
GO - Molecular functioni
- identical protein binding Source: IntAct
Protein-protein interaction databases
BioGRIDi | 31531, 68 interactors |
ComplexPortali | CPX-1387, Synaptonemal complex |
DIPi | DIP-2372N |
IntActi | P14291, 13 interactors |
MINTi | P14291 |
STRINGi | 4932.YLR263W |
Miscellaneous databases
RNActi | P14291, protein |
Family & Domainsi
Phylogenomic databases
eggNOGi | ENOG502QVW0, Eukaryota |
HOGENOMi | CLU_334647_0_0_1 |
InParanoidi | P14291 |
OMAi | MRRESTK |
Family and domain databases
InterProi | View protein in InterPro IPR012491, Red1/Rec10 |
Pfami | View protein in Pfam PF07964, Red1, 1 hit |
PIRSFi | PIRSF001747, Rec10_Red1, 1 hit |
i Sequence
Sequence statusi: Complete.
P14291-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEGLKKKIFG VCLKNDLAQT RNETKGIHYG LMTLETSKQL QEFLHLLVIK
60 70 80 90 100
REVIQNFELL FHIINVAVKI TDSNLPSDDI WHFILKLRFS SEINIDEDSK
110 120 130 140 150
VLNYLLETGI AMENPVSWKC LAVISSILSS VPQSKKIITN LIETEHAKKI
160 170 180 190 200
GQLFDNIQDL QQGNFLVEIL SNCFKKSASN SKKVEKIPQL WQSRSKNKFF
210 220 230 240 250
FENEFYPFSS KNGSLQTCQF LCNNFMSTLS FTGILRQVSY SGSETLKNLR
260 270 280 290 300
IFKKKDDENS YFIQCIYNKI YLWLDEKAPL EFERKKIRIT KNLKNKIQIK
310 320 330 340 350
LRQPFHECVR TTADKTALLF NKTKGFQLEF EDEKLGETFF HNVNNIPKIS
360 370 380 390 400
EVQNFLVLDY IEEEPENEGE EEEQIGRADE QKEDEEEESL DELSTPMVYP
410 420 430 440 450
IKSSIPHNHN EKVQLVTPDR SVSIRSDEWD LKSNTEDEEG NVLADLKISS
460 470 480 490 500
TKETKRQTDY VHIDSEDQSP VVSAQMRKMR RESTKTLEIL RQEFKDKDVQ
510 520 530 540 550
NKEDQSEQIQ NPFVNTSSLV VGKSCLVNPK EKPNIDQTVV GITELKSNSS
560 570 580 590 600
IKKRDINILD TIFGQPPSKK QKQFHKKEKK KQQKKLTNFK PIIDVPSQDK
610 620 630 640 650
RNLRSNAPTK PKSIKVSKLR TDKKVTGEKS SPETAAEKVD DQTVRSNDEQ
660 670 680 690 700
AMSRATKEKC FPDVNEGKEI TKDDAKVSLE SKKNNETFVD SSVVEKHTPP
710 720 730 740 750
DKDCNNCNIT DILESTTVID LQSPHGLSAP GQNTFTNKLQ EQIYSSINHF
760 770 780 790 800
SNELVRKISI INQELNKKIL KELSEKYQKL FSELQDNFQN DTNEMLKFMG
810 820
EIKDMMNLPE DQLVHAIRTR KFDNNKR
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X16183 Genomic DNA Translation: CAA34306.1 U17244 Genomic DNA Translation: AAB67376.1 BK006945 Genomic DNA Translation: DAA09576.1 |
PIRi | JQ0308, COBYD1 |
RefSeqi | NP_013365.1, NM_001182150.1 |
Genome annotation databases
EnsemblFungii | YLR263W_mRNA; YLR263W; YLR263W |
GeneIDi | 850968 |
KEGGi | sce:YLR263W |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X16183 Genomic DNA Translation: CAA34306.1 U17244 Genomic DNA Translation: AAB67376.1 BK006945 Genomic DNA Translation: DAA09576.1 |
PIRi | JQ0308, COBYD1 |
RefSeqi | NP_013365.1, NM_001182150.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 31531, 68 interactors |
ComplexPortali | CPX-1387, Synaptonemal complex |
DIPi | DIP-2372N |
IntActi | P14291, 13 interactors |
MINTi | P14291 |
STRINGi | 4932.YLR263W |
PTM databases
iPTMneti | P14291 |
Proteomic databases
PaxDbi | P14291 |
PRIDEi | P14291 |
Genome annotation databases
EnsemblFungii | YLR263W_mRNA; YLR263W; YLR263W |
GeneIDi | 850968 |
KEGGi | sce:YLR263W |
Organism-specific databases
SGDi | S000004253, RED1 |
VEuPathDBi | FungiDB:YLR263W |
Phylogenomic databases
eggNOGi | ENOG502QVW0, Eukaryota |
HOGENOMi | CLU_334647_0_0_1 |
InParanoidi | P14291 |
OMAi | MRRESTK |
Miscellaneous databases
PROi | PR:P14291 |
RNActi | P14291, protein |
Family and domain databases
InterProi | View protein in InterPro IPR012491, Red1/Rec10 |
Pfami | View protein in Pfam PF07964, Red1, 1 hit |
PIRSFi | PIRSF001747, Rec10_Red1, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | RED1_YEAST | |
Accessioni | P14291Primary (citable) accession number: P14291 Secondary accession number(s): D6VYR0 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 1, 1990 |
Last sequence update: | January 1, 1990 | |
Last modified: | February 10, 2021 | |
This is version 162 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD - Yeast chromosome XII
Yeast (Saccharomyces cerevisiae) chromosome XII: entries and gene names