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Protein

40S ribosomal protein SA

Gene

Rpsa

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. Acts as a PPP1R16B-dependent substrate of PPP1CA (By similarity). Enables malignant tumor cells to penetrate laminin tissue and vessel barriers. Activates precursor thymic anti-OFA/iLRP specific cytotoxic T-cell. May induce CD8 T-suppressor cells secreting IL-10.UniRule annotation5 Publications

Miscellaneous

This protein appears to have acquired a second function as a laminin receptor specifically in the vertebrate lineage.
It is thought that in vertebrates 37/67 kDa laminin receptor acquired a dual function during evolution. It developed from the ribosomal protein SA, playing an essential role in the protein biosynthesis lacking any laminin binding activity, to a cell surface receptor with laminin binding activity.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • laminin binding Source: MGI
  • laminin receptor activity Source: UniProtKB-UniRule
  • ribosome binding Source: MGI
  • structural constituent of ribosome Source: GO_Central

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionReceptor, Ribonucleoprotein, Ribosomal protein

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
40S ribosomal protein SAUniRule annotation
Alternative name(s):
37 kDa laminin receptor precursorUniRule annotation
Short name:
37LRPUniRule annotation
37 kDa oncofetal antigen
37/67 kDa laminin receptorUniRule annotation
Short name:
LRP/LRUniRule annotation
67 kDa laminin receptorUniRule annotation
Short name:
67LRUniRule annotation
Laminin receptor 1UniRule annotation
Short name:
LamRUniRule annotation
Laminin-binding protein precursor p40UniRule annotation
Short name:
LBP/p40UniRule annotation
OFA/iLRP
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Rpsa
Synonyms:Lamr1, P40-8
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 9

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:105381 Rpsa

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell membrane, Cytoplasm, Membrane, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

More...
ChEMBLi
CHEMBL1075301

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedUniRule annotation1 Publication
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001343592 – 29540S ribosomal protein SAAdd BLAST294

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylserineUniRule annotation1 Publication1
Modified residuei43PhosphoserineBy similarity1
Modified residuei52N6-acetyllysineBy similarity1
Modified residuei89N6-acetyllysine; alternateCombined sources1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki89Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateBy similarity
Modified residuei97PhosphothreonineBy similarity1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Acylated. Acylation may be a prerequisite for conversion of the monomeric 37 kDa laminin receptor precursor (37LRP) to the mature dimeric 67 kDa laminin receptor (67LR), and may provide a mechanism for membrane association.UniRule annotation
Cleaved by stromelysin-3 (ST3) at the cell surface. Cleavage by stromelysin-3 may be a mechanism to alter cell-extracellular matrix interactions.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections (‘Function’, ‘PTM / Processing’, ‘Pathology and Biotech’) according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei115 – 116Cleavage; by ST3; site 1UniRule annotation2
Sitei133 – 134Cleavage; by ST3; site 2UniRule annotation2

Keywords - PTMi

Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
P14206

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
P14206

MaxQB - The MaxQuant DataBase

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MaxQBi
P14206

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
P14206

PeptideAtlas

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PeptideAtlasi
P14206

PRoteomics IDEntifications database

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PRIDEi
P14206

2D gel databases

REPRODUCTION-2DPAGE

More...
REPRODUCTION-2DPAGEi
IPI00123604
P14206

Two-dimensional polyacrylamide gel electrophoresis database from the Geneva University Hospital

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SWISS-2DPAGEi
P14206

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P14206

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

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PhosphoSitePlusi
P14206

SwissPalm database of S-palmitoylation events

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SwissPalmi
P14206

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSMUSG00000032518 Expressed in 127 organ(s), highest expression level in thymus

CleanEx database of gene expression profiles

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CleanExi
MM_RPSA

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
P14206 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

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Genevisiblei
P14206 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Monomer (37LRP) and homodimer (67LR) (By similarity). Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Interacts with RPS21 (By similarity). Interacts with several laminins including at least LAMB1. Interacts with MDK. Interacts with PRNP. The mature dimeric form interacts with PPP1R16B (via its fourth ankyrin repeat). Interacts with PPP1CA only in the presence of PPP1R16B (By similarity).UniRule annotation

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
201107, 5 interactors

Database of interacting proteins

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DIPi
DIP-38089N

Protein interaction database and analysis system

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IntActi
P14206, 19 interactors

Molecular INTeraction database

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MINTi
P14206

STRING: functional protein association networks

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STRINGi
10090.ENSMUSP00000035105

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

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ProteinModelPortali
P14206

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
P14206

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati230 – 232[DE]-W-[ST] 13
Repeati247 – 249[DE]-W-[ST] 23
Repeati266 – 268[DE]-W-[ST] 33
Repeati275 – 277[DE]-W-[ST] 43
Repeati293 – 295[DE]-W-[ST] 53

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni54 – 113Interaction with PPP1R16BUniRule annotationAdd BLAST60
Regioni161 – 180Laminin-bindingUniRule annotationAdd BLAST20
Regioni205 – 229Laminin-bindingUniRule annotationAdd BLAST25
Regioni242 – 295Laminin-bindingUniRule annotationAdd BLAST54

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the universal ribosomal protein uS2 family.UniRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
KOG0830 Eukaryota
COG0052 LUCA

Ensembl GeneTree

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GeneTreei
ENSGT00940000153327

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

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HOGENOMi
HOG000232073

The HOVERGEN Database of Homologous Vertebrate Genes

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HOVERGENi
HBG054466

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
P14206

KEGG Orthology (KO)

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KOi
K02998

Identification of Orthologs from Complete Genome Data

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OMAi
QQKTKDM

Database of Orthologous Groups

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OrthoDBi
1129610at2759

Database for complete collections of gene phylogenies

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PhylomeDBi
P14206

TreeFam database of animal gene trees

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TreeFami
TF300100

Family and domain databases

Conserved Domains Database

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CDDi
cd01425 RPS2, 1 hit

HAMAP database of protein families

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HAMAPi
MF_03015 Ribosomal_S2_euk, 1 hit
MF_03016 Ribosomal_S2_laminin_receptor, 1 hit

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR027504 40S_ribosomal_SA
IPR032281 40S_SA_C
IPR001865 Ribosomal_S2
IPR018130 Ribosomal_S2_CS
IPR027498 Ribosomal_S2_euk
IPR005707 Ribosomal_S2_euk/arc
IPR023591 Ribosomal_S2_flav_dom_sf

The PANTHER Classification System

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PANTHERi
PTHR11489 PTHR11489, 1 hit

Pfam protein domain database

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Pfami
View protein in Pfam
PF16122 40S_SA_C, 1 hit
PF00318 Ribosomal_S2, 2 hits

Protein Motif fingerprint database; a protein domain database

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PRINTSi
PR00395 RIBOSOMALS2

Superfamily database of structural and functional annotation

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SUPFAMi
SSF52313 SSF52313, 1 hit

TIGRFAMs; a protein family database

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TIGRFAMsi
TIGR01012 uS2_euk_arch, 1 hit

PROSITE; a protein domain and family database

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PROSITEi
View protein in PROSITE
PS00962 RIBOSOMAL_S2_1, 1 hit
PS00963 RIBOSOMAL_S2_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

P14206-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSGALDVLQM KEEDVLKFLA AGTHLGGTNL DFQMEQYIYK RKSDGIYIIN
60 70 80 90 100
LKRTWEKLLL AARAIVAIEN PADVSVISSR NTGQRAVLKF AAATGATPIA
110 120 130 140 150
GRFTPGTFTN QIQAAFREPR LLVVTDPRAD HQPLTEASYV NLPTIALCNT
160 170 180 190 200
DSPLRYVDIA IPCNNKGAHS VGLMWWMLAR EVLRMRGTIS REHPWEVMPD
210 220 230 240 250
LYFYRDPEEI EKEEQAAAEK AVTKEEFQGE WTAPAPEFTA AQPEVADWSE
260 270 280 290
GVQVPSVPIQ QFPTEDWSAQ PATEDWSAAP TAQATEWVGA TTEWS
Length:295
Mass (Da):32,838
Last modified:May 1, 2007 - v4
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC698CFA6B759FD2E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1L1SRW0A0A1L1SRW0_MOUSE
40S ribosomal protein SA
Rpsa
93Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1L1SUK3A0A1L1SUK3_MOUSE
40S ribosomal protein SA
Rpsa
133Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti18F → L in AAA39413 (PubMed:2531008).Curated1
Sequence conflicti29N → H in BAB27355 (PubMed:16141072).Curated1
Sequence conflicti155R → A in AAA39413 (PubMed:2531008).Curated1
Sequence conflicti243P → T in AAH92041 (PubMed:15489334).Curated1
Sequence conflicti249S → Y in BAC38701 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
J02870 mRNA Translation: AAA39413.1
X06406 mRNA Translation: CAA29696.1
AF140348 mRNA Translation: AAD26866.1
DQ360291 Genomic DNA Translation: ABC95972.1
DQ360292 Genomic DNA Translation: ABC95977.1
AK010423 mRNA Translation: BAB26926.1
AK010985 mRNA Translation: BAB27306.1
AK011041 mRNA Translation: BAB27353.1
AK011043 mRNA Translation: BAB27355.1
AK075778 mRNA Translation: BAC35952.1
AK075790 mRNA Translation: BAC35960.1
AK082935 mRNA Translation: BAC38701.1
AK088954 mRNA Translation: BAC40671.1
AK134224 mRNA Translation: BAE22057.1
AK135488 mRNA Translation: BAE22550.1
AK160551 mRNA Translation: BAE35867.1
AK160625 mRNA Translation: BAE35924.1
AK165219 mRNA Translation: BAE38083.1
AK166697 mRNA Translation: BAE38953.1
AK166874 mRNA Translation: BAE39085.1
AK167132 mRNA Translation: BAE39278.1
BC003829 mRNA Translation: AAH03829.1
BC037195 mRNA Translation: AAH37195.1
BC055886 mRNA Translation: AAH55886.1
BC081461 mRNA Translation: AAH81461.1
BC084677 mRNA Translation: AAH84677.1
BC092041 mRNA Translation: AAH92041.1
BC094902 mRNA Translation: AAH94902.1
BC099601 mRNA Translation: AAH99601.1
BC110285 mRNA Translation: AAI10286.1

The Consensus CDS (CCDS) project

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CCDSi
CCDS23623.1

Protein sequence database of the Protein Information Resource

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PIRi
A29395

NCBI Reference Sequences

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RefSeqi
NP_035159.3, NM_011029.4

UniGene gene-oriented nucleotide sequence clusters

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UniGenei
Mm.311972
Mm.391708
Mm.4071

Genome annotation databases

Ensembl eukaryotic genome annotation project

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Ensembli
ENSMUST00000035105; ENSMUSP00000035105; ENSMUSG00000032518
ENSMUST00000217317; ENSMUSP00000148933; ENSMUSG00000032518

Database of genes from NCBI RefSeq genomes

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GeneIDi
16785

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
mmu:16785

UCSC genome browser

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UCSCi
uc009scd.2 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J02870 mRNA Translation: AAA39413.1
X06406 mRNA Translation: CAA29696.1
AF140348 mRNA Translation: AAD26866.1
DQ360291 Genomic DNA Translation: ABC95972.1
DQ360292 Genomic DNA Translation: ABC95977.1
AK010423 mRNA Translation: BAB26926.1
AK010985 mRNA Translation: BAB27306.1
AK011041 mRNA Translation: BAB27353.1
AK011043 mRNA Translation: BAB27355.1
AK075778 mRNA Translation: BAC35952.1
AK075790 mRNA Translation: BAC35960.1
AK082935 mRNA Translation: BAC38701.1
AK088954 mRNA Translation: BAC40671.1
AK134224 mRNA Translation: BAE22057.1
AK135488 mRNA Translation: BAE22550.1
AK160551 mRNA Translation: BAE35867.1
AK160625 mRNA Translation: BAE35924.1
AK165219 mRNA Translation: BAE38083.1
AK166697 mRNA Translation: BAE38953.1
AK166874 mRNA Translation: BAE39085.1
AK167132 mRNA Translation: BAE39278.1
BC003829 mRNA Translation: AAH03829.1
BC037195 mRNA Translation: AAH37195.1
BC055886 mRNA Translation: AAH55886.1
BC081461 mRNA Translation: AAH81461.1
BC084677 mRNA Translation: AAH84677.1
BC092041 mRNA Translation: AAH92041.1
BC094902 mRNA Translation: AAH94902.1
BC099601 mRNA Translation: AAH99601.1
BC110285 mRNA Translation: AAI10286.1
CCDSiCCDS23623.1
PIRiA29395
RefSeqiNP_035159.3, NM_011029.4
UniGeneiMm.311972
Mm.391708
Mm.4071

3D structure databases

ProteinModelPortaliP14206
SMRiP14206
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi201107, 5 interactors
DIPiDIP-38089N
IntActiP14206, 19 interactors
MINTiP14206
STRINGi10090.ENSMUSP00000035105

Chemistry databases

ChEMBLiCHEMBL1075301

PTM databases

iPTMnetiP14206
PhosphoSitePlusiP14206
SwissPalmiP14206

2D gel databases

REPRODUCTION-2DPAGEiIPI00123604
P14206
SWISS-2DPAGEiP14206

Proteomic databases

EPDiP14206
jPOSTiP14206
MaxQBiP14206
PaxDbiP14206
PeptideAtlasiP14206
PRIDEiP14206

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000035105; ENSMUSP00000035105; ENSMUSG00000032518
ENSMUST00000217317; ENSMUSP00000148933; ENSMUSG00000032518
GeneIDi16785
KEGGimmu:16785
UCSCiuc009scd.2 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
3921
MGIiMGI:105381 Rpsa

Phylogenomic databases

eggNOGiKOG0830 Eukaryota
COG0052 LUCA
GeneTreeiENSGT00940000153327
HOGENOMiHOG000232073
HOVERGENiHBG054466
InParanoidiP14206
KOiK02998
OMAiQQKTKDM
OrthoDBi1129610at2759
PhylomeDBiP14206
TreeFamiTF300100

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Rpsa mouse

Protein Ontology

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PROi
PR:P14206

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000032518 Expressed in 127 organ(s), highest expression level in thymus
CleanExiMM_RPSA
ExpressionAtlasiP14206 baseline and differential
GenevisibleiP14206 MM

Family and domain databases

CDDicd01425 RPS2, 1 hit
HAMAPiMF_03015 Ribosomal_S2_euk, 1 hit
MF_03016 Ribosomal_S2_laminin_receptor, 1 hit
InterProiView protein in InterPro
IPR027504 40S_ribosomal_SA
IPR032281 40S_SA_C
IPR001865 Ribosomal_S2
IPR018130 Ribosomal_S2_CS
IPR027498 Ribosomal_S2_euk
IPR005707 Ribosomal_S2_euk/arc
IPR023591 Ribosomal_S2_flav_dom_sf
PANTHERiPTHR11489 PTHR11489, 1 hit
PfamiView protein in Pfam
PF16122 40S_SA_C, 1 hit
PF00318 Ribosomal_S2, 2 hits
PRINTSiPR00395 RIBOSOMALS2
SUPFAMiSSF52313 SSF52313, 1 hit
TIGRFAMsiTIGR01012 uS2_euk_arch, 1 hit
PROSITEiView protein in PROSITE
PS00962 RIBOSOMAL_S2_1, 1 hit
PS00963 RIBOSOMAL_S2_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRSSA_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P14206
Secondary accession number(s): Q58E74
, Q8BHL0, Q8BNL2, Q91V31, Q9CY13
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: May 1, 2007
Last modified: January 16, 2019
This is version 182 of the entry and version 4 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families
  3. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
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