UniProtKB - P14135 (RL6_HALMA)
Protein
50S ribosomal protein L6
Gene
rpl6
Organism
Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
Status
Functioni
This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
GO - Molecular functioni
- rRNA binding Source: UniProtKB-UniRule
- structural constituent of ribosome Source: InterPro
GO - Biological processi
- translation Source: UniProtKB-UniRule
Keywordsi
Molecular function | Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding |
Names & Taxonomyi
Protein namesi | Recommended name: 50S ribosomal protein L6UniRule annotationAlternative name(s): Hl10 Hmal6 |
Gene namesi | Name:rpl6UniRule annotation Ordered Locus Names:rrnAC1596 |
Organismi | Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui) |
Taxonomic identifieri | 272569 [NCBI] |
Taxonomic lineagei | Archaea › Euryarchaeota › Stenosarchaea group › Halobacteria › Halobacteriales › Haloarculaceae › Haloarcula › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Initiator methioninei | Removed2 Publications | |||
ChainiPRO_0000131083 | 2 – 178 | 50S ribosomal protein L6Add BLAST | 177 |
Interactioni
Subunit structurei
Part of the 50S ribosomal subunit.
Interacts weakly with protein L13.
UniRule annotation2 PublicationsProtein-protein interaction databases
STRINGi | 272569.rrnAC1596 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | P14135 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P14135 |
Family & Domainsi
Sequence similaritiesi
Belongs to the universal ribosomal protein uL6 family.UniRule annotation
Phylogenomic databases
eggNOGi | arCOG04090, Archaea |
HOGENOMi | CLU_065464_0_0_2 |
OMAi | VFQDGIY |
Family and domain databases
Gene3Di | 3.90.930.12, 2 hits |
HAMAPi | MF_01365_A, Ribosomal_L6_A, 1 hit |
InterProi | View protein in InterPro IPR000702, Ribosomal_L6 IPR020040, Ribosomal_L6_a/b-dom IPR036789, Ribosomal_L6_a/b-dom_sf IPR002359, Ribosomal_L6_CS2 IPR019907, Ribosomal_L6P_arc |
PANTHERi | PTHR11655, PTHR11655, 1 hit |
Pfami | View protein in Pfam PF00347, Ribosomal_L6, 2 hits |
PIRSFi | PIRSF002162, Ribosomal_L6, 1 hit |
SUPFAMi | SSF56053, SSF56053, 2 hits |
TIGRFAMsi | TIGR03653, uL6_arch, 1 hit |
PROSITEi | View protein in PROSITE PS00700, RIBOSOMAL_L6_2, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P14135-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPRVELEIPE DVDAEQDHLD ITVEGDNGSV TRRLWYPDID VSVDGDTVVI
60 70 80 90 100
ESDEDNAKTM STIGTFQSHI ENMFHGVTEG WEYGMEVFYS HFPMQVNVEG
110 120 130 140 150
DEVVIENFLG EKAPRRTTIH GDTDVEIDGE ELTVSGPDIE AVGQTAADIE
160 170
QLTRINDKDV RVFQDGVYIT RKPNRGDA
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural varianti | 3 | R → S. | 1 | |
Natural varianti | 24 | E → S. | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X58395 Genomic DNA Translation: CAA41287.1 AY596297 Genomic DNA Translation: AAV46514.1 |
PIRi | S16538, R5HS6L |
RefSeqi | WP_011223740.1, NZ_CP039138.1 |
Genome annotation databases
EnsemblBacteriai | AAV46514; AAV46514; rrnAC1596 |
GeneIDi | 40152561 |
KEGGi | hma:rrnAC1596 |
PATRICi | fig|272569.17.peg.2285 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X58395 Genomic DNA Translation: CAA41287.1 AY596297 Genomic DNA Translation: AAV46514.1 |
PIRi | S16538, R5HS6L |
RefSeqi | WP_011223740.1, NZ_CP039138.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1C04 | X-ray | 5.00 | B | 21-25 | [»] | |
1FFK | X-ray | 2.40 | 1 | 2-178 | [»] | |
1JJ2 | X-ray | 2.40 | E | 2-178 | [»] | |
1K73 | X-ray | 3.01 | G | 2-178 | [»] | |
1K8A | X-ray | 3.00 | G | 2-178 | [»] | |
1K9M | X-ray | 3.00 | G | 2-178 | [»] | |
1KC8 | X-ray | 3.01 | G | 2-178 | [»] | |
1KD1 | X-ray | 3.00 | G | 2-178 | [»] | |
1KQS | X-ray | 3.10 | E | 2-178 | [»] | |
1M1K | X-ray | 3.20 | G | 2-178 | [»] | |
1M90 | X-ray | 2.80 | G | 2-178 | [»] | |
1N8R | X-ray | 3.00 | G | 2-178 | [»] | |
1NJI | X-ray | 3.00 | G | 2-178 | [»] | |
1Q7Y | X-ray | 3.20 | G | 2-178 | [»] | |
1Q81 | X-ray | 2.95 | G | 2-178 | [»] | |
1Q82 | X-ray | 2.98 | G | 2-178 | [»] | |
1Q86 | X-ray | 3.00 | G | 2-178 | [»] | |
1QVF | X-ray | 3.10 | E | 2-178 | [»] | |
1QVG | X-ray | 2.90 | E | 2-178 | [»] | |
1S72 | X-ray | 2.40 | E | 1-178 | [»] | |
1VQ4 | X-ray | 2.70 | E | 1-178 | [»] | |
1VQ5 | X-ray | 2.60 | E | 1-178 | [»] | |
1VQ6 | X-ray | 2.70 | E | 1-178 | [»] | |
1VQ7 | X-ray | 2.50 | E | 1-178 | [»] | |
1VQ8 | X-ray | 2.20 | E | 1-178 | [»] | |
1VQ9 | X-ray | 2.40 | E | 1-178 | [»] | |
1VQK | X-ray | 2.30 | E | 1-178 | [»] | |
1VQL | X-ray | 2.30 | E | 1-178 | [»] | |
1VQM | X-ray | 2.30 | E | 1-178 | [»] | |
1VQN | X-ray | 2.40 | E | 1-178 | [»] | |
1VQO | X-ray | 2.20 | E | 1-178 | [»] | |
1VQP | X-ray | 2.25 | E | 1-178 | [»] | |
1W2B | X-ray | 3.50 | E | 2-178 | [»] | |
1YHQ | X-ray | 2.40 | E | 1-178 | [»] | |
1YI2 | X-ray | 2.65 | E | 1-178 | [»] | |
1YIJ | X-ray | 2.60 | E | 1-178 | [»] | |
1YIT | X-ray | 2.80 | E | 1-178 | [»] | |
1YJ9 | X-ray | 2.90 | E | 1-178 | [»] | |
1YJN | X-ray | 3.00 | E | 1-178 | [»] | |
1YJW | X-ray | 2.90 | E | 1-178 | [»] | |
2OTJ | X-ray | 2.90 | E | 1-178 | [»] | |
2OTL | X-ray | 2.70 | E | 1-178 | [»] | |
2QA4 | X-ray | 3.00 | E | 1-178 | [»] | |
2QEX | X-ray | 2.90 | E | 1-178 | [»] | |
3CC2 | X-ray | 2.40 | E | 1-178 | [»] | |
3CC4 | X-ray | 2.70 | E | 1-178 | [»] | |
3CC7 | X-ray | 2.70 | E | 1-178 | [»] | |
3CCE | X-ray | 2.75 | E | 1-178 | [»] | |
3CCJ | X-ray | 2.70 | E | 1-178 | [»] | |
3CCL | X-ray | 2.90 | E | 1-178 | [»] | |
3CCM | X-ray | 2.55 | E | 1-178 | [»] | |
3CCQ | X-ray | 2.90 | E | 1-178 | [»] | |
3CCR | X-ray | 3.00 | E | 1-178 | [»] | |
3CCS | X-ray | 2.95 | E | 1-178 | [»] | |
3CCU | X-ray | 2.80 | E | 1-178 | [»] | |
3CCV | X-ray | 2.90 | E | 1-178 | [»] | |
3CD6 | X-ray | 2.75 | E | 1-178 | [»] | |
3CMA | X-ray | 2.80 | E | 1-178 | [»] | |
3CME | X-ray | 2.95 | E | 1-178 | [»] | |
3CPW | X-ray | 2.70 | E | 1-178 | [»] | |
3CXC | X-ray | 3.00 | E | 2-178 | [»] | |
3G4S | X-ray | 3.20 | E | 2-173 | [»] | |
3G6E | X-ray | 2.70 | E | 2-173 | [»] | |
3G71 | X-ray | 2.85 | E | 2-173 | [»] | |
3I55 | X-ray | 3.11 | E | 1-178 | [»] | |
3I56 | X-ray | 2.90 | E | 1-178 | [»] | |
3OW2 | X-ray | 2.70 | E | 2-173 | [»] | |
4ADX | electron microscopy | 6.60 | E | 1-178 | [»] | |
4V9F | X-ray | 2.40 | E | 1-178 | [»] | |
SMRi | P14135 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
STRINGi | 272569.rrnAC1596 |
Genome annotation databases
EnsemblBacteriai | AAV46514; AAV46514; rrnAC1596 |
GeneIDi | 40152561 |
KEGGi | hma:rrnAC1596 |
PATRICi | fig|272569.17.peg.2285 |
Phylogenomic databases
eggNOGi | arCOG04090, Archaea |
HOGENOMi | CLU_065464_0_0_2 |
OMAi | VFQDGIY |
Miscellaneous databases
EvolutionaryTracei | P14135 |
Family and domain databases
Gene3Di | 3.90.930.12, 2 hits |
HAMAPi | MF_01365_A, Ribosomal_L6_A, 1 hit |
InterProi | View protein in InterPro IPR000702, Ribosomal_L6 IPR020040, Ribosomal_L6_a/b-dom IPR036789, Ribosomal_L6_a/b-dom_sf IPR002359, Ribosomal_L6_CS2 IPR019907, Ribosomal_L6P_arc |
PANTHERi | PTHR11655, PTHR11655, 1 hit |
Pfami | View protein in Pfam PF00347, Ribosomal_L6, 2 hits |
PIRSFi | PIRSF002162, Ribosomal_L6, 1 hit |
SUPFAMi | SSF56053, SSF56053, 2 hits |
TIGRFAMsi | TIGR03653, uL6_arch, 1 hit |
PROSITEi | View protein in PROSITE PS00700, RIBOSOMAL_L6_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | RL6_HALMA | |
Accessioni | P14135Primary (citable) accession number: P14135 Secondary accession number(s): P12739, Q5V1T8 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 1, 1990 |
Last sequence update: | January 23, 2007 | |
Last modified: | December 2, 2020 | |
This is version 145 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencing, Reference proteomeDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families - Ribosomal proteins
Ribosomal proteins families and list of entries